All Stories

  1. Uncovering viral protein acquisition events and human-specific folds with pairwise comparisons of predicted protein structures

    Article • Molecular Biology and Evolution, April 2026, Oxford University Press (OUP)

    Noam Auslander

  2. Single-cell lineage tracing maps clonal and transcriptional dynamics in melanoma metastasis

    Article • April 2026, openRxiv

    Noam Auslander

  3. Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance

    Article • Molecular Cancer, March 2026, Springer Science + Business Media

    Noam Auslander

  4. OncoBERT: Context-Aware Modeling of Somatic Mutations for Precision Oncology

    Article • February 2026, openRxiv

    Noam Auslander

  5. A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis

    Article • December 2025, openRxiv

    Noam Auslander

  6. Taxonomy-free fecal microbiome profiles enable robust prediction of immunotherapy response and toxicity in melanoma

    Article • November 2025, openRxiv

    Noam Auslander

  7. Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer

    Article • Genes & Development, November 2025, Cold Spring Harbor Laboratory Press

    Noam Auslander

  8. kMermaid: Ultrafast metagenomic read assignment to protein clusters by hashing of amino acid k-mer frequencies

    Article • PLoS Computational Biology, September 2025, PLOS

    Noam Auslander

  9. Targeting LxCxE Cleft Pocket of Retinoblastoma Protein in Immunosuppressive Macrophages Inhibits Ovarian Cancer Progression

    Article • Cancer Immunology Research, September 2025, American Association for Cancer Research (AACR)

    Noam Auslander

  10. Parkin activates innate immunity and promotes antitumor immune responses

    Article • Journal of Clinical Investigation, August 2024, American Society for Clinical Investigation

    Noam Auslander

  11. A selective S-acyltransferase inhibitor suppresses tumor growth

    Article • July 2024, openRxiv

    Noam Auslander

  12. Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease

    Article • Nature Microbiology, May 2024, Springer Science + Business Media

    Noam Auslander

  13. Microbial gene expression analysis of healthy and cancerous esophagus uncovers bacterial biomarkers of clinical outcomes

    Article • ISME Communications, December 2023, Oxford University Press (OUP)

    Noam Auslander

  14. An African-Specific Variant of TP5 3 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

    Article • Cancer Discovery, May 2023, American Association for Cancer Research (AACR)

    Noam Auslander

  15. Computational Methods Summarizing Mutational Patterns in Cancer: Promise and Limitations for Clinical Applications

    Article • Cancers, March 2023, MDPI AG

    Noam Auslander

  16. A deep learning approach reveals unexplored landscape of viral expression in cancer

    Article • Nature Communications, February 2023, Springer Science + Business Media

    Noam Auslander

  17. The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer

    Article • Science Immunology, September 2022, American Association for the Advancement of Science

    Noam Auslander

  18. Mutated processes predict immune checkpoint inhibitor therapy benefit in metastatic melanoma

    Article • Nature Communications, September 2022, Springer Science + Business Media

    Noam Auslander

  19. Gene-expression profiles of pretreatment biopsies predict complete response of rectal cancer patients to preoperative chemoradiotherapy

    Article • British Journal of Cancer, May 2022, Springer Science + Business Media

    Noam Auslander

  20. Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

    Article • Genome Medicine, May 2021, Springer Science + Business Media

    Noam Auslander

  21. Identification of combinations of somatic mutations that predict cancer survival and immunotherapy benefit

    Article • NAR Cancer, April 2021, Oxford University Press (OUP)

    Noam Auslander

  22. Incorporating Machine Learning into Established Bioinformatics Frameworks

    Article • International Journal of Molecular Sciences, March 2021, MDPI AG

    Noam Auslander

  23. The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases

    Article • Molecular Systems Biology, December 2020, Springer Science + Business Media

    Noam Auslander

  24. Prediction of the incubation period for COVID-19 and future virus disease outbreaks

    Article • BMC Biology, November 2020, Springer Science + Business Media

    Noam Auslander

  25. Seeker: alignment-free identification of bacteriophage genomes by deep learning

    Article • Nucleic Acids Research, October 2020, Oxford University Press (OUP)

    Noam Auslander

  26. Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

    Article • Cancer Research, October 2020, American Association for Cancer Research (AACR)

    Noam Auslander

  27. Single-Cell–Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response

    Article • Clinical Cancer Research, July 2020, American Association for Cancer Research (AACR)

    Noam Auslander

  28. Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

    Article • Proceedings of the National Academy of Sciences, June 2020, Proceedings of the National Academy of Sciences

    Noam Auslander

  29. Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability

    Article • Nature Communications, March 2020, Springer Science + Business Media

    Noam Auslander

  30. Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer

    Article • Scientific Reports, November 2019, Springer Science + Business Media

    Noam Auslander

  31. A unique insert in the genomes of high-risk human papillomaviruses with a predicted dual role in conferring oncogenic risk

    Article • F1000Research, October 2019, Faculty of 1000, Ltd.

    Noam Auslander

  32. A sequence unique to high risk HPV, that it may confer the oncogenic potential of these strains

    Article • F1000Research, July 2019, Faculty of 1000, Ltd.

    Noam Auslander

  33. In silico learning of tumor evolution through mutational time series

    Article • Proceedings of the National Academy of Sciences, April 2019, Proceedings of the National Academy of Sciences

    Noam Auslander

  34. Predicting Complete Remission of Acute Myeloid Leukemia: Machine Learning Applied to Gene Expression

    Article • Cancer Informatics, January 2019, SAGE Publications

    Yu Fan, Noam Auslander

  35. Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

    Article • Cell, September 2018, Elsevier

    Noam Auslander

  36. Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

    Article • Nature Medicine, August 2018, Springer Science + Business Media

    Noam Auslander

  37. Harnessing synthetic lethality to predict the response to cancer treatment

    Article • Nature Communications, June 2018, Springer Science + Business Media

    Noam Auslander

  38. An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer

    Article • Molecular Systems Biology, December 2017, EMBO

    Noam Auslander

  39. Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

    Article • Molecular Cancer Research, October 2017, American Association for Cancer Research (AACR)

    Noam Auslander

  40. Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome

    Article • eLife, October 2017, eLife

    Noam Auslander

  41. Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction

    Article • PLoS Computational Biology, September 2016, PLOS

    Noam Auslander

  42. A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer

    Article • Scientific Reports, July 2016, Springer Science + Business Media

    Noam Auslander