All Stories

  1. Combination therapy with broadly neutralizing antibodies, antiretroviral therapy and CCR5 blockade limits viral reservoir seeding in infant macaque model of HIV
  2. Planning for the future of the American Society for Microbiology’s Health Unit by the Council on Microbial Sciences
  3. Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines
  4. Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis
  5. CD4+ T Cells Are Dispensable for Induction of Broad Heterologous HIV Neutralizing Antibodies in Rhesus Macaques
  6. A large repertoire of B cell lineages targeting one cluster of epitopes in a vaccinated rhesus macaque
  7. Protection of Newborn Macaques by Plant-Derived HIV Broadly Neutralizing Antibodies: a Model for Passive Immunotherapy during Breastfeeding
  8. Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques
  9. Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
  10. Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic
  11. Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques
  12. Polyfunctional Tier 2–Neutralizing Antibodies Cloned following HIV-1 Env Macaque Immunization Mirror Native Antibodies in a Human Donor
  13. Virus Control in Vaccinated Rhesus Macaques Is Associated with Neutralizing and Capturing Antibodies against the SHIV Challenge Virus but Not with V1V2 Vaccine–Induced Anti-V2 Antibodies Alone
  14. Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge
  15. ACTIVating Resources for the COVID-19 Pandemic: In Vivo Models for Vaccines and Therapeutics
  16. An HIV Vaccine Targeting the V2 Region of the HIV Envelope Induces a Highly Durable Polyfunctional Fc-Mediated Antibody Response in Rhesus Macaques
  17. Rapid Induction of Multifunctional Antibodies in Rabbits and Macaques by Clade C HIV-1 CAP257 Envelopes Circulating During Epitope-Specific Neutralization Breadth Development
  18. Adenosine deaminase-1 enhances germinal center formation and functional antibody responses to HIV-1 Envelope DNA and protein vaccines
  19. Pediatric HIV: the Potential of Immune Therapeutics to Achieve Viral Remission and Functional Cure
  20. Cloning and functional testing of rhesus macaque (Macaca mulatta) IL‐9 and IL‐33
  21. Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity
  22. A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge
  23. Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses
  24. Simian-Human Immunodeficiency Virus SHIV.CH505 Infection of Rhesus Macaques Results in Persistent Viral Replication and Induces Intestinal Immunopathology
  25. Human natural killer cells mediate adaptive immunity to viral antigens
  26. Antibodies Tip the Balance Towards an HIV Cure
  27. IL-33 enhances the kinetics and quality of the antibody response to a DNA and protein-based HIV-1 Env vaccine
  28. Divergent HIV-1-Directed Immune Responses Generated by Systemic and Mucosal Immunization with Replicating Single-Cycle Adenoviruses in Rhesus Macaques
  29. Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth
  30. Tribute to Bonnie Mathieson
  31. Antibodies pose a double threat to HIV
  32. Reduced Cell-Associated DNA and Improved Viral Control in Macaques following Passive Transfer of a Single Anti-V2 Monoclonal Antibody and Repeated Simian/Human Immunodeficiency Virus Challenges
  33. Functional Antibody Response Against V1V2 and V3 of HIV gp120 in the VAX003 and VAX004 Vaccine Trials
  34. Passive and active antibody studies in primates to inform HIV vaccines
  35. Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses
  36. Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques
  37. Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge
  38. The Critical Role of Nonhuman Primates in Medical Research - White Paper
  39. Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination
  40. Pre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Env-specific antibody response in SHIV-infected rhesus macaques
  41. Use of broadly neutralizing antibodies for HIV-1 prevention
  42. E2 multimeric scaffold for vaccine formulation: immune response by intranasal delivery and transcriptome profile of E2-pulsed dendritic cells
  43. Evaluation of protection induced by a dengue virus serotype 2 envelope domain III protein scaffold/DNA vaccine in non-human primates
  44. Induction of neutralizing antibodies in rhesus macaques using V3 mimotope peptides
  45. Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques
  46. Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens
  47. Animal models in HIV-1 protection and therapy
  48. Functional and Molecular Characteristics of Novel and Conserved Cross-Clade HIV Envelope Specific Human Monoclonal Antibodies
  49. Tied down by its own receptor
  50. Multimeric Scaffolds Displaying the HIV-1 Envelope MPER Induce MPER-Specific Antibodies and Cross-Neutralizing Antibodies when Co-Immunized with gp160 DNA
  51. Development of Broadly Neutralizing Anti-HIV-1 Antibodies during Natural Infection through Early Epitope Acquisition and Subsequent Maturation
  52. Envelope Variants Circulating as Initial Neutralization Breadth Developed in Two HIV-Infected Subjects Stimulate Multiclade Neutralizing Antibodies in Rabbits
  53. Emergence of Broadly Neutralizing Antibodies and Viral Coevolution in Two Subjects during the Early Stages of Infection with Human Immunodeficiency Virus Type 1
  54. Vaccine Delivery to the Oral Cavity Using Coated Microneedles Induces Systemic and Mucosal Immunity
  55. Improvement of antibody responses by HIV envelope DNA and protein co-immunization
  56. HIV-1 Envelope Glycoprotein Resistance to Monoclonal Antibody 2G12 Is Subject-Specific and Context-Dependent in Macaques and Humans
  57. SIV infection of rhesus macaques of Chinese origin: a suitable model for HIV infection in humans
  58. Neutralizing Polyclonal IgG Present during Acute Infection Prevents Rapid Disease Onset in Simian-Human Immunodeficiency Virus SHIVSF162P3-Infected Infant Rhesus Macaques
  59. E2 multimeric scaffolds displaying HIV-1 Envelope regions elicit V3 and MPER-specific neutralizing antibody and T cell responses when combined with gp160 plasmid DNA
  60. Motif-optimized subtype A HIV envelope-based DNA vaccines rapidly elicit neutralizing antibodies when delivered sequentially
  61. Lessons in Nonhuman Primate Models for AIDS Vaccine Research: From Minefields to Milestones
  62. Co-Immunization with Multimeric Scaffolds and DNA Rapidly Induces Potent Autologous HIV-1 Neutralizing Antibodies and CD8+ T Cells
  63. Neutralizing Antibodies and Control of HIV: Moves and Countermoves
  64. Sequential Immunization with a Subtype B HIV-1 Envelope Quasispecies Partially Mimics the In Vivo Development of Neutralizing Antibodies
  65. HIV-1 Gag p17 presented as virus-like particles on the E2 scaffold from Geobacillus stearothermophilus induces sustained humoral and cellular immune responses in the absence of IFNγ production by CD4+ T cells
  66. Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques
  67. Introduction
  68. Update on animal models for HIV research
  69. Blocking and tackling HIV
  70. Nonhuman primate models for pediatric AIDS
  71. The Infectious Molecular Clone and Pseudotyped Virus Models of Human Immunodeficiency Virus Type 1 Exhibit Significant Differences in Virion Composition with Only Moderate Differences in Infectivity and Inhibition Sensitivity
  72. Immune Responses to Measles and Tetanus Vaccines Among Kenyan Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Children Pre- and Post-Highly Active Antiretroviral Therapy and Revaccination
  73. High Specific Infectivity of Plasma Virus from the Pre-Ramp-Up and Ramp-Up Stages of Acute Simian Immunodeficiency Virus Infection
  74. Continuous Viral Escape and Selection by Autologous Neutralizing Antibodies in Drug-Naïve Human Immunodeficiency Virus Controllers
  75. Too close for comfort
  76. The Use of Nonhuman Primate Models in HIV Vaccine Development
  77. Pediatric AIDS: Maternal–Fetal and Maternal–Infant Transmission of Lentiviruses and Effects on Infant Development in Nonhuman Primates
  78. Transmission of HIV-1 in the Face of Neutralizing Antibodies
  79. Mutations in Envelope gp120 Can Impact Proteolytic Processing of the gp160 Precursor and Thereby Affect Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 Pseudoviruses
  80. Macaques Infected with a CCR5-Tropic Simian/Human Immunodeficiency Virus (SHIV) Develop Broadly Reactive Anti-HIV Neutralizing Antibodies
  81. Evidence for Persistent, Occult Infection in Neonatal Macaques following Perinatal Transmission of Simian-Human Immunodeficiency Virus SF162P3
  82. Evaluation of Passively Transferred, Nonneutralizing Antibody-Dependent Cellular Cytotoxicity-Mediating IgG in Protection of Neonatal Rhesus Macaques against Oral SIVmac251 Challenge
  83. Insights into neutralizing antibodies and HIV Envelope
  84. Consistent Patterns of Change during the Divergence of Human Immunodeficiency Virus Type 1 Envelope from That of the Inoculated Virus in Simian/Human Immunodeficiency Virus-Infected Macaques
  85. Differentiation of a passive vaccine and the humoral immune response toward infection: Analysis of phage displayed peptides
  86. Animal models for perinatal transmission of HIV-1
  87. High Maternal HIV-1 Viral Load During Pregnancy Is Associated With Reduced Placental Transfer of Measles IgG Antibody
  88. Infection with a molecularly cloned SIVsm virus elicits high titer homologous neutralizing antibodies with heterologous neutralizing activity
  89. Human Immunodeficiency Virus Type 1 Subtype B Ancestral Envelope Protein Is Functional and Elicits Neutralizing Antibodies in Rabbits Similar to Those Elicited by a Circulating Subtype B Envelope
  90. Recommendations for the Design and Use of Standard Virus Panels To Assess Neutralizing Antibody Responses Elicited by Candidate Human Immunodeficiency Virus Type 1 Vaccines
  91. Multigene DNA Priming-Boosting Vaccines Protect Macaques from Acute CD4+-T-Cell Depletion after Simian-Human Immunodeficiency Virus SHIV89.6P Mucosal Challenge
  92. New recombinant vaccines based on the use of prokaryotic antigen-display systems
  93. Perinatal transmission of SHIV‐SF162P3 in Macaca nemestrina
  94. Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin
  95. Passive Immunotherapy in Simian Immunodeficiency Virus-Infected Macaques Accelerates the Development of Neutralizing Antibodies
  96. Protective Immunity to SIV Challenge Elicited by Vaccination of Macaques with Multigenic DNA Vaccines Producing Virus-Like Particles
  97. Immunoprophylaxis to Prevent Mother-to-Child Transmission of HIV-1
  98. Macaque blood-derived antigen-presenting cells elicit SIV-specific immune responses
  99. Transfer of neutralizing IgG to macaques 6 h but not 24 h after SHIV infection confers sterilizing protection: Implications for HIV-1 vaccine development
  100. Multigene DNA Priming-Boosting Vaccines Protect Macaques from Acute CD4+-T-Cell Depletion after Simian-Human Immunodeficiency Virus SHIV89.6P Mucosal Challenge
  101. DNA vaccine strategies: candidates for immune modulation and immunization regimens
  102. Multigene DNA prime-boost vaccines for SHIV89.6P
  103. Role of neutralizing antibodies in HIV infection
  104. Determination of a Statistically Valid Neutralization Titer in Plasma That Confers Protection against Simian-Human Immunodeficiency Virus Challenge following Passive Transfer of High-Titered Neutralizing Antibodies
  105. Progress and challenges in therapies for AIDS in nonhuman primate models
  106. Immunization against SIVmne in macaques using multigenic DNA vaccines
  107. Neutralizing antibody responses in Africa green monkeys naturally infected with simian immunodeficiency virus (SIVagm)
  108. Protection from pathogenic SIV challenge using multigenic DNA vaccines
  109. Human immunodeficiency virus type 1 neutralizing antibodies accelerate clearance of cell–free virions from blood plasma
  110. Neutralizing antibody directed against the HIV–1 envelope glycoprotein can completely block HIV–1/SIV chimeric virus infections of macaque monkeys
  111. Early Postinfection Antiviral Treatment Reduces Viral Load and Prevents CD4 + Cell Decline in HIV Type 2-Infected Macaques
  112. Titration of a Vaccine Stock Preparation of Human Immunodeficiency Virus Type 1 sf2 in Cultured Lymphocytes and in Chimpanzees
  113. Passive immune globulin therapy in the SIV/macaque model: early intervention can alter disease profile
  114. Resistance of chimpanzees immunized with recombinant gp120SF2 to challenge by HIV-1SF2
  115. Characterization of a CD4-Expressing Macaque Cell Line That Can Detect Virus after a Single Replication Cycle and Can Be Infected by Diverse Simian Immunodeficiency Virus Isolates
  116. Fine Analysis of Humoral Antibody Response to Envelope Glycoprotein of SIV in Infected and Vaccinated Macaques
  117. Reduced Virus Load in Rhesus Macaques Immunized with Recombinant gp160 and Challenged with Simian Immunodeficiency Virus
  118. V3 variability can influence the ability of an antibody to neutralize or enhance infection by diverse strains of human immunodeficiency virus type 1.
  119. Nonaffinity Purification of Recombinant gp120 for Use in AIDS Vaccine Development
  120. B-Cell Abnormalities in AIDS: Stable and Clonally-Restricted Antibody Response in HIV-1 Infection
  121. HIV-1 Envelope gp120 Alters Astrocytes in Human Brain Cultures
  122. Molecular Profile of an Antibody Response to HIV-1 as Probed by Combinatorial Libraries
  123. Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis
  124. Inactivated Whole SIV Vaccine in Macaques: Evaluation of Protective Efficacy Against Challenge with Cell-Free Virus or Infected Cells
  125. SIV and FIV Vaccine Studies at UC Davis: 1991 Update
  126. Distinction of human immunodeficiency virus type 1 neutralization and infection enhancement by human monoclonal antibodies to glycoprotein 120.
  127. Antibodies are produced to the variable regions of the external envelope glycoprotein of human immunodeficiency virus type 1 in chimpanzees infected with the virus and baboons immunized with a candidate recombinant vaccine
  128. Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge.
  129. Functional and Immunological Characterization of SIV Envelope Glycoprotein Produced in Genetically Engineered Mammalian Cells
  130. Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/CD4 binding in human immunodeficiency virus 1-infected humans.
  131. Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells
  132. Antibody Reactivity to Deletion Mutants of the HIV-1 SF2 Envelope
  133. Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope protein.
  134. Importance of Hypervariable Regions of HIV-1 gp120 in the Generation of Virus Neutralizing Antibodies
  135. Variants of human tissue-type plasminogen activator substituted at the protease cleavage site and glycosylation sites, and truncated at the N- and C-termini
  136. Locations of three repetitive sequence families found in BALB/c adult β-globin clones
  137. DNA sequence organization of the β-globin complex in the BALB/c mouse
  138. The recognition site of type II restriction enzyme BglI is interrupted
  139. Gene Enrichment
  140. Nonhuman Primate Models for AIDS