All Stories

  1. Design of Hybrid Bioactive Peptides Derived From Cecropin and Cathepsin for Therapeutic Application

    Article • Chemical Biology & Drug Design, November 2025, Wiley

    Dr Montserrat Heras

  2. Unleashing IbKTP-NH2, a kyotorphin derivative, against bacterial and fungal multispecies biofilm adhesion and viability on materials

    Article • Journal of Applied Microbiology, August 2025, Oxford University Press (OUP)

    Dr Montserrat Heras

  3. Design of Natterins-based peptides improves antimicrobial and antiviral activities

    Article • Biotechnology Reports, March 2025, Elsevier

    Dr Montserrat Heras

  4. Mechanistic insights on the antibacterial action of the kyotorphin peptide derivatives revealed by in vitro studies and Galleria mellonella proteomic analysis

    Article • Microbial Pathogenesis, April 2024, Elsevier

    Dr Montserrat Heras

  5. Evaluation of the Anti-biofilm Efficacy of Kyotorphin Derivatives and Biosafety Assessment: In Vitro and In Vivo Investigations Targeting Bacterial and Fungal Pathogens

    Article • International Journal of Peptide Research and Therapeutics, March 2024, Springer Science + Business Media

    Dr Montserrat Heras

  6. TUTORING PROGRAM FOR FIRST-YEAR UNIVERSITY STUDENTS: AN ESSENTIAL APPROACH TO REDUCE DROPOUT RATES

    Article • March 2023, IATED Academy, S.L.

    Dr Montserrat Heras, Dr Marcel Verges

  7. Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors

    Article • Journal of Venomous Animals and Toxins including Tropical Diseases, January 2021, FapUNIFESP (SciELO)

    Dr Montserrat Heras

  8. The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer’s Disease Pathophysiology

    Article • Frontiers in Pharmacology, July 2020, Frontiers

    Margarida Martins, Dr Montserrat Heras

  9. Antifungal and anti-biofilm activity of designed derivatives from kyotorphin

    Article • Fungal Biology, May 2020, Elsevier

    Miguel Castanho, Dr Montserrat Heras

  10. Neuropeptide Kyotorphin Impacts on Lipopolysaccharide-Induced Glucocorticoid-Mediated Inflammatory Response. A Molecular Link to Nociception, Neuroprotection, and Anti-Inflammatory Action

    Article • ACS Chemical Neuroscience, May 2017, American Chemical Society (ACS)

    Miguel Castanho, Dr Montserrat Heras

  11. Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance

    Article • Scientific Reports, March 2017, Nature

    Miguel Castanho, Dr Montserrat Heras

  12. Endothelium-Mediated Action of Analogues of the Endogenous Neuropeptide Kyotorphin (Tyrosil-Arginine): Mechanistic Insights from Permeation and Effects on Microcirculation

    Article • ACS Chemical Neuroscience, June 2016, American Chemical Society (ACS)

    Miguel Castanho, Dr Montserrat Heras

  13. Amidated and Ibuprofen-Conjugated Kyotorphins Promote Neuronal Rescue and Memory Recovery in Cerebral Hypoperfusion Dementia Model

    Article • Frontiers in Aging Neuroscience, January 2016, Frontiers

    Miguel Castanho, Dr Montserrat Heras

  14. Improvement of the pharmacological properties of amidated kyotorphin by means of iodination

    Article • MedChemComm, January 2016, Royal Society of Chemistry

    Miguel Castanho, Dr Montserrat Heras

  15. The anti-inflammatory action of the analgesic kyotorphin neuropeptide derivatives: insights of a lipid-mediated mechanism

    Article • Amino Acids, September 2015, Springer Science + Business Media

    Miguel Castanho, Dr Montserrat Heras

  16. Synthesis of new unnatural Nα-Fmoc pyrimidin-4-one amino acids: use of the p-benzyloxybenzyloxy group as a pyrimidinone masking group

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Dr Montserrat Heras

  17. Correlation between membrane translocation and analgesic efficacy in kyotorphin derivatives

    Article • Biopolymers, January 2015, Wiley

    Miguel Castanho, Dr Montserrat Heras

  18. DEPBT as Coupling Reagent To Avoid Racemization in a Solution-Phase Synthesis of a Kyotorphin Derivative

    Article • Synthesis, April 2014, Thieme Publishing Group

    Dr Montserrat Heras

  19. Lyngbouilloside and Related Macrolides from Marine Cyanobacteria

    Article • Natural Product Communications, July 2013, SAGE Publications

    Dr Montserrat Heras

  20. Side-effects of analgesic kyotorphin derivatives: advantages over clinical opioid drugs

    Article • Amino Acids, March 2013, Springer Science + Business Media

    Miguel Castanho, Dr Montserrat Heras

  21. Antimicrobial properties of analgesic kyotorphin peptides unraveled through atomic force microscopy

    Article • Biochemical and Biophysical Research Communications, April 2012, Elsevier

    Miguel Castanho, Dr Montserrat Heras

  22. Total Synthesis of Nominal Lyngbouilloside Aglycon

    Article • Organic Letters, December 2011, American Chemical Society (ACS)

    Dr Montserrat Heras, Dr Stellios Arseniyadis

  23. Chemical Conjugation of the Neuropeptide Kyotorphin and Ibuprofen Enhances Brain Targeting and Analgesia

    Article • Molecular Pharmaceutics, October 2011, American Chemical Society (ACS)

    Miguel Castanho, Dr Montserrat Heras

  24. Inhibition of nociceptive responses after systemic administration of amidated kyotorphin

    Article • British Journal of Pharmacology, June 2011, Wiley

    Miguel Castanho, Dr Montserrat Heras

  25. Coupling reaction between electron-rich pyrimidinones and α-amino acids promoted by phosphonium salts

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Dr Montserrat Heras

  26. Expedient Synthesis of a Stereoisomer of Acremolide B

    Article • The Journal of Organic Chemistry, November 2010, American Chemical Society (ACS)

    Dr Montserrat Heras, Dr Stellios Arseniyadis

  27. Two Concise Total Syntheses of (−)-Bitungolide F

    Article • Organic Letters, August 2010, American Chemical Society (ACS)

    Dr Montserrat Heras, Dr Stellios Arseniyadis

  28. A simple approach for the synthesis of new pyrimidinyl α-amino acids

    Article • Tetrahedron, January 2010, Elsevier

    Dr Montserrat Heras

  29. Synthesis of pyrimidinyl arylglycines through subsequent Mitsunobu and Petasis reactions

    Article • Tetrahedron, May 2008, Elsevier

    Dr Montserrat Heras

  30. A simple approach for the regioselective synthesis of imidazo[1,2-a]pyrimidiones and pyrimido[1,2-a]pyrimidinones

    Article • Tetrahedron, February 2006, Elsevier

    Dr Montserrat Heras, Anthony Linden

  31. A Hetero-Diels−Alder Approach to Phosphonothiashikimic Acid and New Thiaglycosides

    Article • European Journal of Organic Chemistry, January 2004, Wiley

    Dr Montserrat Heras

  32. Synthesis of Triazolo[1,5‐a]triazin‐7‐one Derivatives and Highly Functionalized [1,2,4]Triazoles

    Article • Helvetica Chimica Acta, September 2003, Wiley

    Dr Montserrat Heras, Anthony Linden

  33. Solution- and Solid-Phase Parallel Synthesis of 4-Alkoxy-Substituted Pyrimidines with High Molecular Diversity

    Article • Journal of Combinatorial Chemistry, February 2003, American Chemical Society (ACS)

    Dr Montserrat Heras

  34. Development of an Efficient and Straightforward Methodology Toward the Synthesis of Molecularly Diverse 2,6-Disubstituted 3,4-Dihydropyrimidin-4(3 H )-ones

    Article • Synthesis, January 2002, Thieme Publishing Group

    Dr Montserrat Heras

  35. Synthesis of Novel 2,3-Dihydroimidazo[2,1- b ][1,3]oxazoles Through Intramolecular Nucleophilic ipso -Substitution in 2-Alkylsulfonylimidazoles

    Article • Synthesis, January 2002, Thieme Publishing Group

    Dr Montserrat Heras

  36. Reaction of α-iminomethylene amino esters with mono- and bidentate nucleophiles: a straightforward route to 2-amino-1H-5-imidazolones

    Article • Tetrahedron, May 2001, Elsevier

    Dr Montserrat Heras, Anthony Linden

  37. First synthesis of a phosphonothiashikimic acid derivative

    Article • Chemical Communications, January 2001, Royal Society of Chemistry

    Dr Montserrat Heras

  38. Phosphonodithioformates as heterodienophiles: synthesis of (3,6-dihydro-2H-thiopyran-2-yl)phosphonates

    Article • Tetrahedron Letters, September 2000, Elsevier

    Dr Montserrat Heras

  39. A New Class of Fused Imidazoles by Intramolecular Nucleophilic ipso-Substitution in 2-Alkylsulfonylimidazoles: Synthesis of 2,3-Dihydroimidazo[2,1-b][1,3]oxazoles

    Article • Synthesis, September 1999, Thieme Publishing Group

    Dr Montserrat Heras