All Stories

  1. The Whole Blood Transcriptomic Analysis in Sickle Cell Disease Reveals RUNX3 as a Potential Marker for Vaso-Occlusive Crises
  2. Navigating multiple sclerosis: From clinical categories to clinical management
  3. Enhanced Cytotoxicity and Receptor Modulation by SMA-WIN 55,212-2 Micelles in Glioblastoma Cells
  4. Progressive Elevation of Store-Operated Calcium Entry-Associated Regulatory Factor (SARAF) and Calcium Pathway Dysregulation in Multiple Sclerosis
  5. Calcium Homeostasis Disrupted—How Store-Operated Calcium Entry Factor SARAF Silencing Impacts HepG2 Liver Cancer Cells
  6. Transcriptome dissection reveals the molecular basis of systemic associations in psoriasis
  7. Recombinant ISRAA modulates the cytokine profile in IFN-γ-mediated model of psoriasis in vitro
  8. Recombinant ISRAA ameliorates imiquimod-induced psoriasis and knocking out Israa delays its onset
  9. Association of Leukocyte Telomere Length and the Risk of Disease Severity and Metabolic Comorbidities in Arab Patients with Psoriasis
  10. Recombinant ISRAA ameliorates imiquimod-induced psoriasis and knocking out Israa delays its onset
  11. Pragmatic solutions for the global burden of stroke
  12. Pragmatic solutions for the global burden of stroke
  13. Pragmatic Solutions to Reduce Global Stroke Burden: World Stroke Organization – Lancet Neurology Commission Report
  14. A Rare 46,X,t(Y;10)(q12;p14) Balanced Translocation in Non-Obstructive Azoospermic Patient with Elevated FSH and LH Levels
  15. Acacia nilotica Pod Extract has an Anti-cancer Effect on the U937 Cell Line
  16. Akt1 players promote PMA U937 cell line differentiation into macrophage-like cells
  17. Upregulation of REL and WSB1 in patients with psoriasis and metabolic syndrome
  18. Clinical phenotyping and genetic diagnosis of a large cohort of Sudanese families with hereditary spinocerebellar degenerations
  19. Using a Madurella mycetomatis‐specific PCR on grains obtained via non‐invasive fine‐needle aspirated material is more accurate than cytology
  20. Mirror image polydactyly in a foot of young female with late presentation: management and three years follow-up
  21. Comparing the performance of the common used eumycetoma diagnostic tests
  22. Cross-cultural comparison of mental illness stigma and help-seeking attitudes: a multinational population-based study from 16 Arab countries and 10,036 individuals
  23. Why the mycetoma patients are still neglected
  24. Mitochondrial DNA haplogroup analysis in Saudi Arab patients with multiple sclerosis
  25. Diagnostics to support mycetoma management—Development of two target product profiles
  26. Genomics and metagenomics of Madurella mycetomatis, a causative agent of black grain mycetoma in Sudan
  27. Staphylococcus aureus causing primary foot botryomycosis mimicking actinomycetoma: a case report from Sudan
  28. Role of socioeconomic factors in developing mycetoma: Results from a household survey in Sennar State, Sudan
  29. Wako β‐D‐glucan assay can be used to measure serum β‐D‐glucan in Sudanese patients to aid with diagnosis of eumycetoma caused by Madurella mycetomatis
  30. Estimating the burden of mycetoma in Sudan for the period 1991–2018 using a model-based geostatistical approach
  31. Metagenomic detection of eumycetoma causative agents   from households of patients residing in two Sudanese endemic villages in White Nile State
  32. Epidemiological cut‐off values for itraconazole and ravuconazole for Madurella mycetomatis, the most common causative agent of mycetoma
  33. Individual Risk Factors of Mycetoma Occurrence in Eastern Sennar Locality, Sennar State, Sudan: A Case-Control Study
  34. Mycetoma management and clinical outcomes: the Mycetoma Research Center experience
  35. Systematic whole-genome sequencing reveals an unexpected diversity among actinomycetoma pathogens and provides insights into their antibacterial susceptibilities
  36. Ultrasound‐guided fine‐needle aspiration cytology significantly improved mycetoma diagnosis
  37. Madurella mycetomatis grains within a eumycetoma lesion are clonal
  38. Analysis of the entire mitochondrial genome reveals Leber’s hereditary optic neuropathy mitochondrial DNA mutations in an Arab cohort with multiple sclerosis
  39. Visual ethnographic documentation: a novel tool for mycetoma awareness and advocacy
  40. Mycobacterium avium subsp. paratuberculosis and microbiome profile of patients in a referral gastrointestinal diseases centre in the Sudan
  41. Next-generation sequencing of the whole mitochondrial genome identifies functionally deleterious mutations in patients with multiple sclerosis
  42. Genetic diagnosis in Sudanese and Tunisian families with syndromic intellectual disability through exome sequencing
  43. Systematic whole-genome sequencing reveals an unexpected diversity among actinomycetoma pathogens and provides insights into their antibacterial susceptibilities
  44. Primary stroke prevention worldwide: translating evidence into action
  45. Clinical delineation of myasthenia gravis in the Kingdom of Bahrain
  46. The developed molecular biological identification tools for mycetoma causative agents: An update
  47. Clinical epidemiological characteristics of mycetoma in Eastern Sennar locality, Sennar State, Sudan
  48. Investigation of extreme ultraviolet radiation of highly charged Mo ions from a laser-produced plasma
  49. Prevalence of depression and anxiety among adult patients undergoing chemotherapy in Khartoum, Sudan: A cross-sectional study
  50. Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease
  51. Knocking down Israa, the Zmiz1 intron-nested gene, unveils interrelated T cell activation functions in mouse
  52. Multiple Sclerosis Presenting with Sixth Nerve Palsy in a Child
  53. The Mycetoma Research Centre experience during the COVID-19 pandemic: obstacles and beyond
  54. Flow Cytometry Detection of Sperm DNA Fragmentation and Apoptotic Markers in the Semen of Infertile Males
  55. The state of stroke services across the globe: Report of World Stroke Organization–World Health Organization surveys
  56. Modelling the spatial distribution of mycetoma in Sudan
  57. A role for the immune system-released activating agent (ISRAA) in the ontogenetic development of brain astrocytes
  58. SARS-CoV-2: Targeted managements and vaccine development
  59. A novel bi‐allelic loss‐of‐function mutation in STIM1 expands the phenotype of STIM1 ‐related diseases
  60. Population genetics of 30 insertion/deletion polymorphisms in the Bahraini population
  61. A possible role for ticks in the transmission of Madurella mycetomatis in a mycetoma-endemic village in Sudan
  62. Invasive, aggressive mastoid bone eumycetoma: a treatment challenge
  63. Next‑generation sequencing of the whole mitochondrial genome identifies novel and common variants in patients with psoriasis, type 2 diabetes mellitus and psoriasis with comorbid type 2 diabetes mellitus
  64. A role for the immune system-released activating agent (ISRAA) in the ontogenetic development of brain astrocytes
  65. Analysis of ion radiation characteristics in the middle and late stages of laser-produced Cd plasma evolution in vacuum
  66. Mycetoma spatial geographical distribution in the Eastern Sennar locality, Sennar State, Sudan
  67. Mycetoma caused byMicroascus gracilis:a novel agent of human eumycetoma in Sudan
  68. Surgery in mycetoma-endemic villages: unique experience
  69. The challenges of recruitment in clinical trials in developing countries: the Mycetoma Research Centre experience
  70. Metagenomics of black grains: new highlights in the understanding of eumycetoma
  71. Multiple extensive Madurella mycetomatis eumycetoma lesions: a case report and review of the literature
  72. Human actinomycetoma caused by Actinomadura mexicana in Sudan: the first report
  73. Experimental and theoretical investigation of EUV radiation behavior of laser-produced Zr plasmas
  74. Oral Insulin Delivery Using Poly (Styrene Co-Maleic Acid) Micelles in a Diabetic Mouse Model
  75. Mitochondrial Haplogroup Reveals the Genetic Basis of Diabetes Mellitus Type 2 Comorbidity in Psoriasis
  76. Analysis of extreme ultraviolet spectra of laser-produced Cd plasmas*
  77. Geographical structuring and low diversity of paternal lineages in Bahrain shown by analysis of 27 Y-STRs
  78. A Critical Role for Immune System-released Activating Agent (Israa) in the Ontogenetic Development of the Brain
  79. Host genetic susceptibility to mycetoma
  80. Scaling up mental health services in Sudan: Sudanese psychiatrists’ opinions
  81. Intelligence quotient (IQ) among children with epilepsy: National epidemiological study – Sudan
  82. Mitochondrial DNA Copy Number in Peripheral Blood as a Potential Non-invasive Biomarker for Multiple Sclerosis
  83. Metagenomics of Black Grains: New Highlights in the Understanding Eumycetoma
  84. Diagnosis of Acute Kidney Injury in Children Hospitalized in a Sub-Saharan African Unit by Saliva Urea Nitrogen Dipstick Test
  85. Classification and management of epilepsy and epileptic syndromes in a cohort of 202 school children- a 2 year follow up study- Sudan
  86. Four novel mutations in the mitochondrial ND4 gene of complex�I in patients with multiple sclerosis
  87. Population genetic analysis of 12 X-STRs in a Bahraini population sample (Allele and haplotype frequencies of 12 X-STRs in Bahraini population)
  88. Genetic variation at 27 y-strs in four regions of bahrain
  89. Is Mycetoma a Vector-Borne Disease: The First Report on the Detection of Madurella mycetomatis in Ticks
  90. Sudan's mental health service: challenges and future horizons
  91. The Accuracy of Histopathological and Cytopathological Techniques in the Identification of the Mycetoma Causative Agents
  92. Population genetic data of the 21 autosomal STRs included in GlobalFiler kit of a population sample from the Kingdom of Bahrain
  93. Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan
  94. Interleukin-17 and matrix metalloprotease-9 expression in the mycetoma granuloma
  95. The mouse intron-nested gene, Israa, is expressed in the lymphoid organs and involved in T-cell activation and signaling
  96. Child and adolescent psychiatry training and services in the Middle East region: a current status assessment
  97. Chaetomium atrobrunneum causing human eumycetoma: The first report
  98. Population genetic data of the 21 autosomal STRs included in GlobalFilerTM kit of a population sample from the Kingdom of Bahrain
  99. Associations between ApoE gene and psychological consequences post stroke in a Bahraini cohort
  100. Transverse colonic volvulus after resection of sigmoid volvulus: Presentation of a case report
  101. The Accuracy of Histopathological and Cytopathological Techniques in the Identification of the Mycetoma Causative Agents
  102. Distinct HLA class I and II genotypes and haplotypes are associated with multiple sclerosis in Bahrain
  103. Circulating matrix metalloproteinases and their tissue inhibitors as markers for ethnic variation in pelvic floor tissue integrity
  104. Peripheral blood mitochondrial DNA copy number as a novel potential biomarker for diabetic nephropathy in type�2 diabetes patients
  105. A holistic approach to the mycetoma management
  106. A case report of neurological complications owing to lately diagnosed hyperargininemia emphasizing the role of national neonatal screening policies in the kingdom of Bahrain
  107. Nanomedicine: is it lost in translation?
  108. Can endotracheal intubation be the first step in management of nonconvulsive status epilepticus?
  109. Idiopathic nephrotic syndrome in South African children.
  110. Personalized medicine is the future sustainable knowledge for human well-being
  111. Sphenopalatine Ganglion Block for the Treatment of Acute Migraine Headache
  112. Sildenafil citrate improves the delivery and anticancer activity of doxorubicin formulations in a mouse model of breast cancer
  113. Interleukin 1 receptor antagonist and 2′-5′-oligoadenylate synthetase-like molecules as novel biomarkers for multiple sclerosis patients in Bahrain
  114. Styrene maleic acid encapsulated raloxifene micelles for management of inflammatory bowel disease
  115. The Immunoexpression of Glucocorticoid Receptors in Breast Carcinomas, Lactational Change, and Normal Breast Epithelium and Its Possible Role in Mammary Carcinogenesis
  116. Predictors of Vascular Cognitive Impairment Poststroke in a Middle Eastern (Bahrain) Cohort: A Proposed Case-Control Comparison
  117. Association Between Metacognition and Mood Symptoms Poststroke
  118. Nervous System-Dependent ISRAA: A Novel Fyn Binding Protein
  119. Increased expression of mitochondrial DNA-encoded genes in human renal mesangial cells in response to high glucose-induced reactive oxygen species
  120. Increased oncogenic microRNA-18a expression in the peripheral blood of patients with prostate cancer: A potential novel non-invasive biomarker
  121. Diabetic peripheral neuropathy, is it an autoimmune disease?
  122. Induction of dissociated cytokine profiles by ISRAA with selective critical involvement of ERK1/2 in its signaling functions
  123. Peripheral blood microRNA-15a is a potential biomarker for type 2 diabetes mellitus and pre-diabetes
  124. Plasmodium falciparum population structure in Sudan post artemisinin-based combination therapy
  125. Leishmania donovaniinfluenced cytokines and Toll-like receptors expression among Sudanese visceral leishmaniasis patients
  126. Differential upregulation of the hypothetical transmembrane protein 66 (TMEM66) in multiple sclerosis patients with potential inflammatory response
  127. An interspecies conserved motif of the mouse immune system-released activating agent (ISRAA) induces proliferative effects on human cells
  128. TLTF in Cerebrospinal Fluid for Detection and Staging of T. b. gambiense Infection
  129. Selective newborn screening of inborn errors of amino acids, organic acids and fatty acids metabolism in the Kingdom of Bahrain
  130. Molecular characterization of hepatitis B virus in liver disease patients and asymptomatic carriers of the virus in Sudan
  131. Role of Cytokine Signaling during Nervous System Development
  132. Significant Effects of Smoking Habit on Male Fertility
  133. DNA integrity is a critical molecular indicator for the assessment of male infertility
  134. Malaria Risk Mapping for Control in the Republic of Sudan
  135. First Report on Ambisome-Associated Allergic Reaction in Two Sudanese Leishmaniasis Patients
  136. Chlamydia pneumoniae Induces Chemokine Expression by Platelets in Patients with Atherosclerosis
  137. Brucellosis in camels, cattle and humans: associations and evaluation of serological tests used for diagnosis of the disease in certain nomadic localities in Sudan
  138. First report on Leishmania major/HIV coinfection in a Sudanese patient
  139. A novel nervous-to-immune signalling mechanism mediating innate responses to infections
  140. Case-control Study of Methylenetetrahydrofolate Reductase Mutations and Hyperhomocysteinemia and Risk of Stroke
  141. Induction of Interleukin-18 in Atherosclerotic Patients: A Role for <i>Chlamydia pneumoniae</i>
  142. A Role for Chlamydia pneumoniae in Inducing IL-10, IL-13, IL-18 and the Chemokines CCL3-alpha, CCL3-beta and CCL5 in Atherosclerotic Patients
  143. A novel nervous system‐induced factor inducing immune responses in the spleen
  144. TNF-α and IL-8 in Acute Stroke and the Modulation of these Cytokines by Antiplatelet Agents
  145. Age decreased steady-state concentrations of genistein in plasma, liver, and skeletal muscle in Sprague–Dawley rats
  146. Modulation of immune responses and suppression of experimental autoimmune myasthenia gravis by surgical denervation of the spleen
  147. Effect of antibiotic sub inhibitory concentration on cytolethal distending toxin production by
  148. Isoflavones Improve Plasma Homocysteine Status and Antioxidant Defense System in Healthy Young Men at Rest but Do Not Ameliorate Oxidative Stress Induced by 80% VO<sub>2</sub>pk Exercise
  149. Isoflavones restore altered redox homeostasis of antioxidant enzymes in healthy young men undergoing 80% peak oxygen consumption (VO2pk) exercise
  150. Induction of α and β chemokines by intestinal epithelial cells stimulated with Campylobacter jejuni
  151. The chemokine receptor CCR5 is not a necessary inflammatory mediator in kainic acid-induced hippocampal injury: evidence for a compensatory effect by increased CCR2 and CCR3
  152. Splenic Denervation Suppresses mRNA Gene Expression and Protein Production of IL-1β and IL-6 by Peritoneal Macrophages in both <i>Trypanosoma brucei brucei</i>-Infected and Non-Infected Rats
  153. Campylobacter-stimulated INT407 cells produce dissociated cytokine profiles
  154. Enhanced chemokine response in experimental acute Escherichia coli pyelonephritis in IL-1β-deficient mice
  155. Autonomous Expression of the slo Gene of the Bicistronic nga-slo Operon of Streptococcus pyogenes
  156. Constitutive and inflammatory induction of α and β chemokines in human first trimester forebrain astrocytes and neurons
  157. African trypanosomes activate human fetal brain cells to proliferation and IFN-γ production
  158. Differential induction of cellular responses by live and dead Leishmania promastigotes in healthy donors
  159. Orthodontic tooth movement and de novo synthesis of proinflammatory cytokines
  160. RANTES promotes growth and survival of human first-trimester forebrain astrocytes
  161. Production of Rantes/CCL5 in human gingival fibroblasts challenged with tumor necrosis factor α
  162. Renal cytokine responses in acuteEscherichia colipyelonephritis in IL-6-deficient mice
  163. Effect of triclosan on interferon-γ production and major histocompatibility complex class II expression in human gingival fibroblasts
  164. ANGIOTENSIN II TYPE 1 RECEPTOR ANTAGONIST (LOSARTAN) DOWN-REGULATES TRANSFORMING GROWTH FACTOR-β IN EXPERIMENTAL ACUTE PYELONEPHRITIS
  165. INDUCTION OF INTERFERON γ IN HUMAN GINGIVAL FIBROBLASTS CHALLENGED WITH PHYTOHAEMAGGLUTININ
  166. Interferon-γ induces secretion of trypanosome lymphocyte triggering factor via tyrosine protein kinases
  167. Expression of interleukin-6 in human dorsal root ganglion cells
  168. Chemokines are produced in the brain early during the course of experimental African trypanosomiasis
  169. Early DNA Synthesis and Cytokine Expression in the Nickel Activation of Peripheral Blood Mononuclear Cells in Nickel-Allergic Subjects
  170. Modulation of Early Immune Responses and Suppression of <i>Trypanosoma brucei brucei </i>Infections by Surgical Denervation of the Spleen
  171. Orthodontic Movement Induces High Numbers of Cells Expressing IFN-gamma at mRNA and Protein Levels
  172. Trypanosoma brucei bruceiInduces Interferon‐γ Expression in Rat Dorsal Root Ganglia Cells via a Tyrosine Kinase–Dependent Pathway
  173. Interferon-gamma and Interleukin-12 Genes are Preferentially Expressed During Early Experimental African Trypanosomiasis and Suppressed by Denervation of the Spleen
  174. Chemokines Are Upregulated During Orthodontic Tooth Movement
  175. Cytokine Profiles in the Central Nervous System and the Spleen During the Early Course of Experimental African Trypanosomiasis
  176. Levels of Gamma Interferon and Interleukin-4 Are Inversely Related to the Levels of Their Corresponding Autoantibodies in Patients with Lower Respiratory Tract Infection
  177. A New Cell Enzyme-Linked Immunosorbent Assay Demonstrates Gamma Interferon Suppression by Beta Interferon in Multiple Sclerosis
  178. A Novel Mechanism for Cytokine Regulation: Screening, Selection, and Characterization of Anticytokine Monoclonal and Polyclonal Autoantibodies
  179. Neutralization of Macrophage Inflammatory Protein 2 (MIP-2) and MIP-1α Attenuates Neutrophil Recruitment in the Central Nervous System during Experimental Bacterial Meningitis
  180. Induction of neutralizing autoantibodies to interferon-γ in patients with polyneuropathy
  181. Induction of the trypanosome lymphocyte‐triggering factor (TLTF) and neutralizing antibodies to the TLTF in experimental African trypanosomiasis
  182. Upregulation of the chemokines Rantes, MCP‐1, MIP‐1a and MIP‐2 in early infection with Trypanosoma brucei brucei and inhibition by sympathetic denervation of the spleen
  183. HUMAN FIRST TRIMESTER FOREBRAIN CELLS EXPRESS GENES FOR INFLAMMATORY AND ANTI-INFLAMMATORY CYTOKINES
  184. Linomide suppresses experimental autoimmune neuritis in Lewis rats by inhibiting myelin antigen-reactive T and B cell responses
  185. Induction of cytokines and anti-cytokine autoantibodies in cerebrospinal fluid (CSF) during experimental bacterial meningitis
  186. Tyrosine kinases are required for IFN γ-induced growth of human embryonic forebrain astrocytes
  187. Resistance and susceptibility to experimental autoimmune neuritis in Sprague-Dawley and Lewis rats correlate with different levels of autoreactive T and B cell responses to myelin antigens
  188. Thalidomide Prolongs Experimental Autoimmune Neuritis in Lewis Rats
  189. Recovery from Guillain–Barré Syndrome Is Associated with Increased Levels of Neutralizing Autoantibodies to Interferon-γ
  190. Cytokine autoantibodies in multiple sclerosis, aseptic meningitis and stroke
  191. Enhanced Insulin Release in GK Rats with Forskolin and Mutations in AC-III Gene
  192. Cytokines and anti-cytokine autoantibodies during experimental african trypanosomiasis in mice with disrupted interferon-gamma and interferon-gamma receptor genes.
  193. Interactions between human embryonic forebrain cells and the cytokines interferon-gamma and interleukin-4.
  194. A systemic downregulation of gamma interferon production is associated with acute shigellosis
  195. Cytokine mRNA Profiles during the Course of ExperimentalHaemophilus influenzaeBacterial Meningitis
  196. CYTOKINE GENE EXPRESSION DURING EXPERIMENTAL ESCHERICHIA COLI PYELONEPHRITIS IN MICE
  197. The Gene for a T Lymphocyte Triggering Factor from African Trypanosomes
  198. Haemophilus influenzae and Streptococcus pneumoniae induce different intracerebral mRNA cytokine patterns during the course of experimental bacterial meningitis
  199. Potential role of autoantibodies in the regulation of cytokine responses during bacterial infections
  200. Leishmania aethiopica Derived from Diffuse Leishmaniasis Patients Preferentially Induce mRNA for Interieukin-10 while Those from Localized Leishmaniasis Patients Induce Interferon- 
  201. Tyrosine Kinases Are Required for Interferon- -Stimulated Proliferation of Trypanosoma brucei brucei
  202. Growth Hormone Stimulates Production of Interferon-Gamma by Human Peripheral Mononuclear Cells
  203. Both CD4+ and CD8+ T cells are essential to induce experimental autoimmune myasthenia gravis.
  204. Human and rodent interferon-γ as a growth factor forTrypanosoma brucei
  205. Induction of Interferon-γ,Transforming Growth Factor-γ, and Interleukin-4 in Mouse Strains with Different Susceptibilities toTrypanosoma brucei brucei
  206. Lovastatin Inhibits Interferon-γ-Induced Trypanosoma brucei brucei Proliferation: Evidence for Mevalonate Pathway Involvement
  207. Different trypanozoan species possess CD8 dependent lymphocyte triggering factor-like activity
  208. Suppression of Experimental Autoimmune Myasthenia Gravis After CD8 Depletion is Associated with Decreased IFN-gamma and IL-4
  209. Depletion of CD8+ T cells suppresses the development of experimental autoimmune myasthenia gravis in Lewis rats
  210. Increased Levels of Antibodies to IFN‐γ in Human and Experimental African Trypanosomiasis
  211. Neuronal interferon-γ immunoreactive molecule: Bioactivities and purification
  212. T cell activation by aTrypanosoma brucei brucei-deriyed lymphocyte triggering factor is dependent on tyrosine protein kinases but not on protein kinase C and A
  213. CD8 is critically involved in lymphocyte activation by a T. brucei brucei-released molecule
  214. A Trypanosoma brucei brucei-Derived Factor that Triggers CD8+ Lymphocytes to Interferon-gamma Secretion: Purification, Characterization and Protective Effects In Vivo by Treatment with a Monoclonal Antibody against the Factor
  215. Bidirectional signals betweenTrypanosoma brucei brucei and dorsal root ganglion neurons
  216. Interactions between Trypanosoma brucei and CD8+ T cells
  217. Bidirectional activating signals betweenTrypanosoma brucei and CD8+ T cells: A trypanosome-released factor triggers interferon-γ production that stimulates parasite growth
  218. Gamma interferon expression and major histocompatibility complex induction during measles and vesicular stomatitis virus infections of the brain
  219. Depletion of CD8+ T cells suppresses growth of Trypanosoma brucei brucei and interferon-gamma) production in infected rats