All Stories

  1. Reversing the Irreversible: miRNA-Targeting Mesyl Phosphoramidate Oligonucleotides Restore Sensitivity to Cisplatin and Doxorubicin of KB-8-5 Epidermoid Carcinoma Cells
  2. Синтез серосодержащего предшественника адресных липоконъюгатов
  3. Loop-Structured PEG-Lipoconjugate Enhances siRNA Delivery Mediated by Liner-PEG Containing Liposomes
  4. Preclinical characteristics of siRNA duplexes as targeted adjuvants in malignant growth
  5. Exosomes facilitate mRNA and siRNA delivery using cationic liposomes 2X3-DOPE to rat heart mesenchymal cells <i>in vitro</i>
  6. Corrigendum to “mRNA encoding antibodies against hemagglutinin and nucleoprotein prevents influenza virus infection in vitro” [Biochem. Biophys. Res. Commun. 738 (2024) 150945]
  7. New Cationic Carbohydrate-Modified Amphiphiles and Liposomes for Effective Delivery of Short Nucleic Acids into Eukaryotic Cells
  8. mRNA encoding antibodies against hemagglutinin and nucleoprotein prevents influenza virus infection in vitro
  9. Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA
  10. Stable Polymer-Lipid Hybrid Nanoparticles Based on mcl-Polyhydroxyalkanoate and Cationic Liposomes for mRNA Delivery
  11. Time course of fluorescent-labelled oligonucleotide accumulation in cells with the use of folate receptor-targeted cationic liposomes
  12. Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells in vitro
  13. Novel Efficient Lipid-Based Delivery Systems Enable a Delayed Uptake and Sustained Expression of mRNA in Human Cells and Mouse Tissues
  14. Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cellsin vitro
  15. Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA
  16. Design of Folate-Containing Liposomal Nucleic Acid Delivery Systems for Antitumor Therapy
  17. The Synthesis and Transfection Activity of Disulfide Polycationic Amphiphiles
  18. Influence of Lipid Composition of Cationic Liposomes 2X3-DOPE on mRNA Delivery into Eukaryotic Cells
  19. Symmetric lipophilic polyamines exhibiting antitumor activity
  20. Dendritic Cell-Derived Artificial Microvesicles Inhibit RLS40 Lymphosarcoma Growth in Mice via Stimulation of Th1/Th17 Immune Response
  21. Amination of epoxides as a convenient approach for lipophilic polyamines synthesis
  22. Synthesis of Novel Lipophilic Polyamines via Ugi Reaction and Evaluation of Their Anticancer Activity
  23. Single Shot vs. Cocktail: A Comparison of Mono- and Combinative Application of miRNA-Targeted Mesyl Oligonucleotides for Efficient Antitumor Therapy
  24. New Cysteine-Containing PEG-Glycerolipid Increases the Bloodstream Circulation Time of Upconverting Nanoparticles
  25. Recent Advances in the Synthesis of Polyamine Derivatives and Their Applications
  26. Influence of Liposome Composition on Plasmid DNA Delivery to Eukaryotic Cells
  27. Non-Phosphorus Lipids As New Antitumor Drug Prototypes
  28. Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy
  29. Synthesis of Isonitrile Derivatives of Diglycerides and Carbohydrates as Intermediates for Multicomponent Ugi Reaction
  30. Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems
  31. pH-Dependent Photoinduced Interconversion of Furocoumaric and Furocoumarinic Acids
  32. Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency
  33. Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids
  34. Prospective pharmacological effects of psoralen photoxidation products and their cycloadducts with aminothiols: chemoinformatic analysis
  35. Effects of spacers within a series of novel folate-containing lipoconjugates on the targeted delivery of nucleic acids
  36. Position of Disulfide Bond Determines the Properties of Novel Stimuli‐Responsive Cationic Lipids
  37. Сationic liposomes as delivery systems for nucleic acids
  38. Synthesis of novel lipophilic tetraamines with cytotoxic activity
  39. Targeted Delivery of Nucleic Acids by Folate-Containing Liposomes into KB-3-1 and HEK 293 Cells
  40. New design of cationic alkyl glycoglycerolipids toxic to tumor cells
  41. Novel PEGylated Liposomes Enhance Immunostimulating Activity of isRNA
  42. Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids
  43. A Novel Disulfide-Containing Polycationic Amphiphile: 1,28-Di[(cholest-5-en-3β-yl)disulfanyl]-4,25-dioxo-3,8,12,17,21,26-hexaazaoctacosane Tetrahydrochloride
  44. Targeted delivery of nucleic acids into xenograft tumors mediated by novel folate-equipped liposomes
  45. Polycationic amphiphiles based on triethylenetetramine and their transfection efficacy
  46. Spacer structure and hydrophobicity influences transfection activity of novel polycationic gemini amphiphiles
  47. Systemic delivery of complexes of melanoma RNA with mannosylated liposomes activates highly efficient murine melanoma-specific cytotoxic T cells in vivo
  48. СИСТЕМНОЕ ВВЕДЕНИЕ РНК МЕЛАНОМЫ В КОМПЛЕКСЕ С МАННОЗИЛИРОВАННЫМИ ЛИПОСОМАМИ АКТИВИРУЕТ in vivo ВЫСОКОЭФФЕКТИВНЫЕ ЦИТОТОКСИЧЕСКИЕ Т-ЛИМФОЦИТЫ ПРОТИВ МЕЛАНОМЫ МЫШИ, "Молекулярная биология"
  49. Design, synthesis and transfection efficiency of a novel redox-sensitive polycationic amphiphile
  50. Multicomponent mannose-containing liposomes efficiently deliver RNA in murine immature dendritic cells and provide productive anti-tumour response in murine melanoma model
  51. Synthesis and antitumor activity of new alkyl glycoglycerolipids
  52. Synthesis of new carbohydrate-containing cationic alkyl glycerolipids with antitumor activity
  53. Novel bivalent spermine-based neutral neogalactolipids for modular gene delivery systems
  54. Antitumor phosphate-containing lipids and non-phosphorus alkyl cationic glycerolipids: chemical structures and perspectives of drug development
  55. Structure–transfection activity relationships in a series of novel cationic lipids with heterocyclic head-groups
  56. Synthesis of mannose-containing neoglycolipids as a component of targeted delivery system for transfer of nucleic acids into antigen-presenting cells
  57. Novel cationic liposomes provide highly efficient delivery of DNA and RNA into dendritic cell progenitors and their immature offsets
  58. Novel cholesterol spermine conjugates provide efficient cellular delivery of plasmid DNA and small interfering RNA
  59. Synthesis of bivalent neogalactolipids via modified Staudinger reaction
  60. Comparison of two lipid/DNA complexes of equal composition and different morphology
  61. Synthesis of amino analogues of cholic acid
  62. Synthesis and transfection activity of novel galactosylated polycationic lipid
  63. Synthesis of cholic acid amino analogues by oxime reduction with TiCl3–NaBH3CN
  64. Synthesis of neoglycolipids for the development of non-viral gene delivery systems
  65. Synthesis and delivery activity of new cationic cholesteryl glucosides
  66. Synthesis of positively charged galactose-bearing surfactants
  67. Synthesis of lipid mediators based on 1,2-dialkylglycerol and cholesterol for targeted delivery of oligo- and polynucleotides into hepatocytes
  68. Synthesis of polycationic lipids based on cholesterol and spermine
  69. Novel Cholesterol-Based Cationic Lipids for Gene Delivery
  70. Convenient synthesis of polycationic amphiphiles by the Fukuyama reaction
  71. Synthesis of cationic lipid transfection agents with O,O- or N,O-acetal linkages
  72. Synthesis of new alkyl-type glycerolipids from methylthiomethyl ethers
  73. Positively charged acyl derivatives of carbohydrates as promising transfection agents
  74. Synthesis of cationic cholesterol-containing amphiphiles with an acid-labile linker
  75. Synthesis of Alkyl Glycerolipids with Functional Groups in Their Polar Heads
  76. Synthesis of Cationic Amphiphiles on the Basis of Deoxycholic Acid
  77. A convergent synthesis of (17R,5Z,8Z,11Z,14Z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid analogues and their tritiated derivatives
  78. Synthesis of a 1α-amino-1-deoxy analogue of forskolin
  79. Cationic amphiphiles of both lipid and nonlipid nature in gene therapy
  80. Convenient synthesis of cationic glycerolipids via methylthiomethyl ethers
  81. Synthesis of alkyl glycerolipids with various cationic groups linked directly to the glycerol backbone