All Stories

  1. Targeted Inhibition of Oncogenic microRNAs miR-21, miR-17, and miR-155 Suppresses Tumor Growth and Modulates Immune Response in Colorectal Cancer
  2. Reversing the Irreversible: miRNA-Targeting Mesyl Phosphoramidate Oligonucleotides Restore Sensitivity to Cisplatin and Doxorubicin of KB-8-5 Epidermoid Carcinoma Cells
  3. Синтез серосодержащего предшественника адресных липоконъюгатов
  4. Loop-Structured PEG-Lipoconjugate Enhances siRNA Delivery Mediated by Liner-PEG Containing Liposomes
  5. Preclinical characteristics of siRNA duplexes as targeted adjuvants in malignant growth
  6. Exosomes facilitate mRNA and siRNA delivery using cationic liposomes 2X3-DOPE to rat heart mesenchymal cells <i>in vitro</i>
  7. Corrigendum to “mRNA encoding antibodies against hemagglutinin and nucleoprotein prevents influenza virus infection in vitro” [Biochem. Biophys. Res. Commun. 738 (2024) 150945]
  8. New Cationic Carbohydrate-Modified Amphiphiles and Liposomes for Effective Delivery of Short Nucleic Acids into Eukaryotic Cells
  9. mRNA encoding antibodies against hemagglutinin and nucleoprotein prevents influenza virus infection in vitro
  10. Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA
  11. Stable Polymer-Lipid Hybrid Nanoparticles Based on mcl-Polyhydroxyalkanoate and Cationic Liposomes for mRNA Delivery
  12. Time course of fluorescent-labelled oligonucleotide accumulation in cells with the use of folate receptor-targeted cationic liposomes
  13. Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells in vitro
  14. Novel Efficient Lipid-Based Delivery Systems Enable a Delayed Uptake and Sustained Expression of mRNA in Human Cells and Mouse Tissues
  15. Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cellsin vitro
  16. Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA
  17. Design of Folate-Containing Liposomal Nucleic Acid Delivery Systems for Antitumor Therapy
  18. The Synthesis and Transfection Activity of Disulfide Polycationic Amphiphiles
  19. Influence of Lipid Composition of Cationic Liposomes 2X3-DOPE on mRNA Delivery into Eukaryotic Cells
  20. Symmetric lipophilic polyamines exhibiting antitumor activity
  21. Dendritic Cell-Derived Artificial Microvesicles Inhibit RLS40 Lymphosarcoma Growth in Mice via Stimulation of Th1/Th17 Immune Response
  22. Amination of epoxides as a convenient approach for lipophilic polyamines synthesis
  23. Synthesis of Novel Lipophilic Polyamines via Ugi Reaction and Evaluation of Their Anticancer Activity
  24. Single Shot vs. Cocktail: A Comparison of Mono- and Combinative Application of miRNA-Targeted Mesyl Oligonucleotides for Efficient Antitumor Therapy
  25. New Cysteine-Containing PEG-Glycerolipid Increases the Bloodstream Circulation Time of Upconverting Nanoparticles
  26. Recent Advances in the Synthesis of Polyamine Derivatives and Their Applications
  27. Influence of Liposome Composition on Plasmid DNA Delivery to Eukaryotic Cells
  28. Non-Phosphorus Lipids As New Antitumor Drug Prototypes
  29. Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy
  30. Synthesis of Isonitrile Derivatives of Diglycerides and Carbohydrates as Intermediates for Multicomponent Ugi Reaction
  31. Lipophilic Polyamines as Promising Components of Liposomal Gene Delivery Systems
  32. pH-Dependent Photoinduced Interconversion of Furocoumaric and Furocoumarinic Acids
  33. Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency
  34. Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids
  35. Prospective pharmacological effects of psoralen photoxidation products and their cycloadducts with aminothiols: chemoinformatic analysis
  36. Effects of spacers within a series of novel folate-containing lipoconjugates on the targeted delivery of nucleic acids
  37. Position of Disulfide Bond Determines the Properties of Novel Stimuli‐Responsive Cationic Lipids
  38. Сationic liposomes as delivery systems for nucleic acids
  39. Synthesis of novel lipophilic tetraamines with cytotoxic activity
  40. Targeted Delivery of Nucleic Acids by Folate-Containing Liposomes into KB-3-1 and HEK 293 Cells
  41. New design of cationic alkyl glycoglycerolipids toxic to tumor cells
  42. Novel PEGylated Liposomes Enhance Immunostimulating Activity of isRNA
  43. Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids
  44. A Novel Disulfide-Containing Polycationic Amphiphile: 1,28-Di[(cholest-5-en-3β-yl)disulfanyl]-4,25-dioxo-3,8,12,17,21,26-hexaazaoctacosane Tetrahydrochloride
  45. Targeted delivery of nucleic acids into xenograft tumors mediated by novel folate-equipped liposomes
  46. Polycationic amphiphiles based on triethylenetetramine and their transfection efficacy
  47. Spacer structure and hydrophobicity influences transfection activity of novel polycationic gemini amphiphiles
  48. Systemic delivery of complexes of melanoma RNA with mannosylated liposomes activates highly efficient murine melanoma-specific cytotoxic T cells in vivo
  49. СИСТЕМНОЕ ВВЕДЕНИЕ РНК МЕЛАНОМЫ В КОМПЛЕКСЕ С МАННОЗИЛИРОВАННЫМИ ЛИПОСОМАМИ АКТИВИРУЕТ in vivo ВЫСОКОЭФФЕКТИВНЫЕ ЦИТОТОКСИЧЕСКИЕ Т-ЛИМФОЦИТЫ ПРОТИВ МЕЛАНОМЫ МЫШИ, "Молекулярная биология"
  50. Design, synthesis and transfection efficiency of a novel redox-sensitive polycationic amphiphile
  51. Multicomponent mannose-containing liposomes efficiently deliver RNA in murine immature dendritic cells and provide productive anti-tumour response in murine melanoma model
  52. Synthesis and antitumor activity of new alkyl glycoglycerolipids
  53. Synthesis of new carbohydrate-containing cationic alkyl glycerolipids with antitumor activity
  54. Novel bivalent spermine-based neutral neogalactolipids for modular gene delivery systems
  55. Antitumor phosphate-containing lipids and non-phosphorus alkyl cationic glycerolipids: chemical structures and perspectives of drug development
  56. Structure–transfection activity relationships in a series of novel cationic lipids with heterocyclic head-groups
  57. Synthesis of mannose-containing neoglycolipids as a component of targeted delivery system for transfer of nucleic acids into antigen-presenting cells
  58. Novel cationic liposomes provide highly efficient delivery of DNA and RNA into dendritic cell progenitors and their immature offsets
  59. Novel cholesterol spermine conjugates provide efficient cellular delivery of plasmid DNA and small interfering RNA
  60. Synthesis of bivalent neogalactolipids via modified Staudinger reaction
  61. Comparison of two lipid/DNA complexes of equal composition and different morphology
  62. Synthesis of amino analogues of cholic acid
  63. Synthesis and transfection activity of novel galactosylated polycationic lipid
  64. Synthesis of cholic acid amino analogues by oxime reduction with TiCl3–NaBH3CN
  65. Synthesis of neoglycolipids for the development of non-viral gene delivery systems
  66. Synthesis and delivery activity of new cationic cholesteryl glucosides
  67. Synthesis of positively charged galactose-bearing surfactants
  68. Synthesis of lipid mediators based on 1,2-dialkylglycerol and cholesterol for targeted delivery of oligo- and polynucleotides into hepatocytes
  69. Synthesis of polycationic lipids based on cholesterol and spermine
  70. Novel Cholesterol-Based Cationic Lipids for Gene Delivery
  71. Convenient synthesis of polycationic amphiphiles by the Fukuyama reaction
  72. Synthesis of cationic lipid transfection agents with O,O- or N,O-acetal linkages
  73. Synthesis of new alkyl-type glycerolipids from methylthiomethyl ethers
  74. Positively charged acyl derivatives of carbohydrates as promising transfection agents
  75. Synthesis of cationic cholesterol-containing amphiphiles with an acid-labile linker
  76. Synthesis of Alkyl Glycerolipids with Functional Groups in Their Polar Heads
  77. Synthesis of Cationic Amphiphiles on the Basis of Deoxycholic Acid
  78. A convergent synthesis of (17R,5Z,8Z,11Z,14Z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid analogues and their tritiated derivatives
  79. Synthesis of a 1α-amino-1-deoxy analogue of forskolin
  80. Cationic amphiphiles of both lipid and nonlipid nature in gene therapy
  81. Convenient synthesis of cationic glycerolipids via methylthiomethyl ethers
  82. Synthesis of alkyl glycerolipids with various cationic groups linked directly to the glycerol backbone