All Stories

  1. When means and standard deviations are an incomplete summary of a continuous variable: problems, solutions, and utilising the reference ranges to check normality
  2. Progression from external pilot to definitive randomised controlled trial: a methodological review of progression criteria reporting
  3. Protocol for a cluster randomised controlled trial of the DAFNEplus (Dose Adjustment For Normal Eating) intervention compared with 5x1 DAFNE: a lifelong approach to promote effective self-management in adults with type 1 diabetes
  4. Understanding basic numbers in health and medicine
  5. Methods matter: pilot and feasibility studies in sports medicine
  6. Recurrent sudden unexpected death in infancy: a case series of sibling deaths
  7. Assessing the transparency of informed consent in feasibility and pilot studies: a single-centre quality assurance study protocol
  8. Exploring the implications of different approaches to estimate centre-level adherence using objective adherence data in an adult cystic fibrosis centre – a retrospective observational study
  9. Meeting abstracts from the 5th International Clinical Trials Methodology Conference (ICTMC 2019)
  10. MRI in the diagnosis of fetal developmental brain abnormalities: the MERIDIAN diagnostic accuracy study
  11. Count time series prediction using particle filters
  12. Intravenous antibiotic use and exacerbation events in an adult cystic fibrosis centre: A prospective observational study
  13. Developing new ways of measuring the quality and impact of ambulance service care: the PhOEBE mixed-methods research programme
  14. A Life or “Good Death” Situation? A Worldwide Ecological Study of the National Contexts of Countries That Have and Have Not Implemented Palliative Care
  15. The stepped wedge cluster randomised trial: what it is and when it should be used
  16. A pragmatic behavior-based habit index for adherence to nebulized treatments among adults with cystic fibrosis
  17. Understanding FEV 1 for the purpose of cystic fibrosis registry comparisons: Does bias in annual review FEV 1 affect between‐centre comparison within the UK? An analysis of registry data
  18. Cluster randomised trials
  19. Does evidence support the high expectations placed in precision medicine? A bibliographic review
  20. Reporting of stepped wedge cluster randomised trials: extension of the CONSORT 2010 statement with explanation and elaboration
  21. Emergency hospital care for adults with suspected seizures in the NHS in England 2007–2013: a cross-sectional study
  22. A randomised controlled trial is not a pilot trial simply because it uses a surrogate endpoint
  23. Sample Sizes for Clinical, Laboratory and Epidemiology Studies
  24. The DiPEP study: an observational study of the diagnostic accuracy of clinical assessment, D-dimer and chest x-ray for suspected pulmonary embolism in pregnancy and postpartum
  25. The importance of data issues when comparing cystic fibrosis registry outcomes between countries: Are annual review FEV1 in the UK only collected when subjects are well?
  26. Role of habit in treatment adherence among adults with cystic fibrosis
  27. Basic Design Considerations
  28. Binary Outcomes
  29. Cluster Designs
  30. Confidence Intervals
  31. Continuous Outcomes
  32. Cumulative References
  33. Feasibility and Pilot Studies
  34. Front Matter
  35. Further Design Considerations
  36. Genomic Targets and Dose-Finding
  37. Index
  38. More than Two Groups Designs
  39. Non-Inferiority and Equivalence
  40. Observer Agreement Studies
  41. Ordered Categorical Outcomes
  42. Paired Binary, Ordered Categorical and Continuous Outcomes
  43. Rate Outcomes
  44. Reference Intervals and Receiver Operating Curves
  45. Repeated Outcome Measures
  46. Sample Size Software
  47. Stepped Wedge Designs
  48. Supplemental Images
  49. Survival Time Outcomes
  50. The Correlation Coefficient
  51. Therapeutic Exploratory Trials
  52. Therapeutic Exploratory Trials
  53. Do cystic fibrosis centres with the lowest FEV1 still use the least amount of intravenous antibiotics? A registry-based comparison of intravenous antibiotic use among adult CF centres in the UK
  54. Family lifestyle dynamics and childhood obesity: evidence from the millennium cohort study
  55. Response to Comment on Novodvorsky et al. Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care 2017;40:655–662
  56. Evidence against precision medicine?
  57. 1800 Uk unscheduled admissions for adults with suspected seizures
  58. Use of MRI in the Diagnosis of Fetal Brain Abnormalities in Utero (MERIDIAN)
  59. Predictors of intravenous antibiotic use among adults with cystic fibrosis (CF)
  60. Change in diagnostic confidence brought about by using in utero MRI for fetal structural brain pathology: analysis of the MERIDIAN cohort
  61. Use of MRI in the Diagnosis of Fetal Brain Abnormalities in Utero (MERIDIAN)
  62. Reply
  63. A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial
  64. Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE)
  65. Minimum number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study
  66. An empirical method to cluster objective nebulizer adherence data among adults with cystic fibrosis
  67. Severe acute malnutrition in children aged under 5 years can be successfully managed in a non‐emergency routine community healthcare setting in Ghana
  68. How to set go/no-go rules for clinical trial pilot phases to reduce research waste
  69. Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study
  70. What is propensity score modelling?
  71. Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis patients
  72. Determinants of objective adherence to nebulised medications among adults with cystic fibrosis: an exploratory mixed methods study comparing low and high adherers
  73. Chronic obstructive pulmonary disease in Welsh slate miners
  74. CONSORT 2010 statement: extension to randomised pilot and feasibility trials
  75. CONSORT 2010 statement: extension to randomised pilot and feasibility trials
  76. The effects of breastfeeding on childhood BMI: a propensity score matching approach
  77. Time Series Regression
  78. Acute effects of aircraft noise on cardiovascular admissions – an interrupted time-series analysis of a six-day closure of London Heathrow Airport caused by volcanic ash
  79. Erratum to: Methods and processes for development of a CONSORT extension for reporting pilot randomized controlled trials
  80. Air Pollution and Subtypes, Severity and Vulnerability to Ischemic Stroke—A Population Based Case-Crossover Study
  81. Stepped wedge cluster randomised trials: a review of the statistical methodology used and available
  82. 268 Rescue and prevention in cystic fibrosis: an exploration of the impact of adherence to preventative nebulised therapy upon subsequent rescue therapy with IV antibiotics in adults with CF
  83. WS23.3 Rescue therapy within the UK CF registry: an exploration of the predictors of IV antibiotic use amongst adults with cystic fibrosis
  84. Methods and processes for development of a CONSORT extension for reporting pilot randomized controlled trials
  85. Accurate reporting of adherence to inhaled therapies in adults with cystic fibrosis: methods to calculate normative adherence
  86. Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework
  87. Defining feasibility and pilot studies in preparation for randomised controlled trials: using consensus methods and validation to develop a conceptual framework
  88. Improving the reporting of randomised pilot and feasibility studies: a consort statement extension
  89. P274 Moving from rescue to prevention: real world evidence of reduction in IV antibiotic requirement following improvement in adherence to maintenance nebulised treatment in an adult cystic fibrosis centre: Abstract P274 Table 1
  90. Lowering bed occupancy: a life-saving intervention?
  91. Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps over MDI and Structured Education (REPOSE) trial
  92. The mortality and hospitalization rates associated with the long interdialytic gap in thrice-weekly hemodialysis patients
  93. Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable
  94. Sample size calculations for the design of cluster randomized trials: A summary of methodology
  95. The BMJ report on mortality cuts in hospitals put into special measures in 2013 is misleading
  96. Mortality of babies enrolled in a community-based support programme: CONI PLUS (Care of Next Infant Plus)
  97. Secondary analysis and literature review of community rehabilitation and intermediate care: an information resource
  98. A cluster randomized controlled non-inferiority trial of 5-day Dose Adjustment for Normal Eating (DAFNE) training delivered over 1 week versus 5-day DAFNE training delivered over 5 weeks: the DAFNE 5 × 1-day trial
  99. Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: A longitudinal qualitative investigation
  100. Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic ana...
  101. Adjusting for treatment switching in randomised controlled trials – A simulation study and a simplified two-stage method
  102. Self-monitoring of blood glucose versus self-monitoring of urine glucose in adults with newly diagnosed Type 2 diabetes receiving structured education: a cluster randomized controlled trial
  103. The Potential Value of Ongoing Support In Type-1 Diabetes Mellitus With Dafneplus: Exploratory Pre-Trial Cost-Effectiveness Analysis On Proposed Trial End-Point Target For 12-Month Hba1c Improvement
  104. A hazard ratio was estimated by a ratio of median survival times, but with considerable uncertainty
  105. Clinical Signals
  106. Pulmonary Medicine
  107. Time Series Regression
  108. The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial
  109. Challenges of cluster randomized trials
  110. Pilot and feasibility studies: Is there a difference from each other and from a randomised controlled trial?
  111. PERITONEAL DIALYSIS 1
  112. How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research
  113. Substantial reductions in the number of diabetic ketoacidosis and severe hypoglycaemia episodes requiring emergency treatment lead to reduced costs after structured education in adults with Type 1 diabetes
  114. Estimated Albumin Excretion Rate Versus Urine Albumin-Creatinine Ratio for the Estimation of Measured Albumin Excretion Rate: Derivation and Validation of an Estimated Albumin Excretion Rate Equation
  115. Adjusting Survival Time Estimates to Account for Treatment Switching in Randomized Controlled Trials—an Economic Evaluation Context
  116. Impact of a GP-led walk-in centre on NHS emergency departments
  117. Outdoor air pollution, subtypes and severity of ischemic stroke – a small-area level ecological study
  118. Cluster Randomized Trials
  119. Prognostic Value of Cardiovascular Magnetic Resonance Imaging Measurements Corrected for Age and Sex in Idiopathic Pulmonary Arterial Hypertension
  120. A Guide to Adjusting Survival Time Estimates to Account for Treatment Switching in Randomised Controlled Trials
  121. Definition and reporting of pilot and feasibility studies
  122. Direct risk standardisation: a new method for comparing casemix adjusted event rates using complex models
  123. Mortality indicators used to rank hospital performance
  124. What do hospital mortality rates tell us about quality of care?: Table 1
  125. Variation in centre-specific survival in patients starting renal replacement therapy in England is explained by enhanced comorbidity information from hospitalization data
  126. Pilot study of a brief intervention based on the theory of planned behaviour and self-identity to increase chlamydia testing among young people living in deprived areas
  127. ABR in newborns: Effects of electrode configuration, stimulus rate, and EEG rejection levels on test efficiency
  128. Good Practice Guidelines for the use of Statistical Regression Models in Economic Evaluations
  129. Did hospital mortality in England change from 2005 to 2010? A retrospective cohort analysis
  130. Patients’ experience and satisfaction with GP led walk-in centres in the UK; a cross sectional study
  131. GP-led walk-in centre in the UK: another way for urgent healthcare provision
  132. Doing clinical trials large enough to achieve adequate reductions in uncertainties about treatment effects
  133. How to reduce the risk of failing to reach recruitment targets: lessons learnt from a pump pilot trial
  134. Disparities in Healthcare Utilisation Rates for Aboriginal and Non-Aboriginal Albertan Residents, 1997–2006: A Population Database Study
  135. The 5x1 DAFNE study protocol: a cluster randomised trial comparing a standard 5 day DAFNE course delivered over 1 week against DAFNE training delivered over 1 day a week for 5 consecutive weeks
  136. Home ovulation tests and stress in women trying to conceive: a randomized controlled trial
  137. Rapid-Throughput Skeletal Phenotyping of 100 Knockout Mice Identifies 9 New Genes That Determine Bone Strength
  138. Tutorial in biostatistics: sample sizes for parallel group clinical trials with binary data
  139. Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial
  140. Improved Biomedical and Psychological Outcomes 1 Year After Structured Education in Flexible Insulin Therapy for People With Type 1 Diabetes: The U.K. DAFNE experience
  141. Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care
  142. Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol
  143. Developing a summary hospital mortality index: retrospective analysis in English hospitals over five years
  144. The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes
  145. Clinical effectiveness of a patient decision aid to improve decision quality and glycaemic control in people with diabetes making treatment choices: a cluster randomised controlled trial (PANDAs) in general practice
  146. Chapter 13 The Linkage of Incident Renal Replacement Therapy Patients in England (2002–2006) to Hospital Episodes and National Mortality Data: Improved Demography and Hospitalisation Data in Patients Undergoing Renal Replacement Therapy
  147. A pragmatic quasi-experimental multi-site community intervention trial evaluating the impact of Emergency Care Practitioners in different UK health settings on patient pathways (NEECaP Trial)
  148. Seasonality of medical contacts in school-aged children with asthma: Association with school holidays
  149. Outdoor Air Pollution and Incidence of Ischemic and Hemorrhagic Stroke: A Small-Area Level Ecological Study
  150. Reprinted Article “Carotid Artery Plaque Composition—Relationship to Clinical Presentation and Ultrasound B-mode Imaging”
  151. Long-term Outcomes of Patients With Autoimmune Hepatitis Managed at a Nontransplant Center
  152. Epidemiology of scabies prevalence in the U.K. from general practice records
  153. Sixth International French Society of Statistics meeting on statistical methods in biopharmacy: Recent advances and trends in statistics as applied to clinical trials
  154. Comments on ‘The potential for bias in the reporting of industry sponsored clinical trials’ by Stephen Pyke et al. and ‘Proposed best practice for statisticians in the reporting and publication of pharmaceutical industry sponsored clinical trials’ by Jame
  155. Possible Evidence for a Fall in the Prevalence of High-Functioning Pervasive Developmental Disorder with Age?
  156. Authors' reply
  157. Evaluation of triage methods used to select patients with suspected pandemic influenza for hospital admission: cohort study
  158. Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cost effectiveness analysis
  159. Statistical issues in Primary Care
  160. What is a pilot or feasibility study? A review of current practice and editorial policy
  161. Assessing quality of care from hospital case notes: comparison of reliability of two methods
  162. A statistician on a NICE committee
  163. Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions
  164. Impact of Outdoor Air Pollution on Survival After Stroke: Population-Based Cohort Study
  165. Comparison of case note review methods for evaluating quality and safety in health care
  166. Do South Asian women with PCOS have poorer health-related quality of life than Caucasian women with PCOS? A comparative cross-sectional study
  167. A randomized, controlled dose-ranging study of risedronate in children with moderate and severe osteogenesis imperfecta
  168. Cluster Randomised Trials by HAYES, R. J. and MOULTON, L. H.
  169. Evaluation of the impact of a health forecast alert service on admissions for chronic obstructive pulmonary disease in Bradford and Airedale
  170. Modified-Release Hydrocortisone to Provide Circadian Cortisol Profiles
  171. Sample Size Tables for Clinical Studies
  172. A RANDOMISED CONTROLLED:TRIAL OF DIFFERENT INTENSITIES OF PHYSIOTHERAPY AND DIFFERENT GOAL-SETTING PROCEDURES IN 44 CHILDREN WITH CEREBRAL PALSY
  173. Misinterpreting P-Values In Research
  174. Recurrence rates for sudden infant death syndrome (SIDS): the importance of risk stratification
  175. Evaluating the efficacy of acupuncture in defined aspects of stroke recovery
  176. How common is repeat sudden infant death syndrome?
  177. Optimal Thresholds, Linear or Nonlinear Relationships of Fracture Risk Reduction With Therapy
  178. Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial
  179. Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention)
  180. Impact of a Restraint Training Module on Paramedic Students' Likelihood to Use Restraint Techniques
  181. Fundamentals of Clinical Research: Bridging Medicine, Statistics and Operations by Antonella Bacchieri, Giovanni Della Cioppa
  182. Relationship of Early Changes in Bone Resorption to the Reduction in Fracture Risk With Risedronate: Review of Statistical Analysis
  183. Contamination in trials of educational interventions
  184. Predicting where future means will lie based on the results of the current trial
  185. Invalid methods
  186. Impact of NHS walk-in centres on primary care access times: ecological study
  187. Risk of hypoglycaemia in types 1 and 2 diabetes: effects of treatment modalities and their duration
  188. Combining Growth Hormone Releasing Hormone-Arginine and Synacthen Testing Diminishes the Cortisol Response
  189. Implementing referral guidelines: lessons from a negative outcome cluster randomised factorial trial in general practice
  190. Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain
  191. Language Ability after Early Detection of Permanent Childhood Hearing Impairment
  192. The effect of helium and oxygen on exercise performance in COPD: A randomised crossover trial
  193. The Effect of Helium and Oxygen on Exercise Performance in Chronic Obstructive Pulmonary Disease
  194. Cost-effectiveness and cost-utility of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine
  195. Editorial
  196. Editorial
  197. Statistics at Square Two
  198. Developments in cluster randomized trials andStatistics in Medicine
  199. Non-inferiority trials: continued advancements in concepts and methodology (special papers for the 25th anniversary ofStatistics in Medicine25(7))
  200. The Mann–Whitney statistic: continuous use and discovery
  201. Editorial
  202. Editorial
  203. Editorial
  204. Hypopituitary patients prefer a touch-screen to paper quality of life questionnaire
  205. Do ‘food deserts’ influence fruit and vegetable consumption?—a cross-sectional study
  206. Outdoor air pollution, mortality, and hospital admissions from coronary heart disease in Sheffield, UK: a small-area level ecological study
  207. Life and death decisions: A statistician on a data monitoring and ethics committee
  208. Universal newborn screening for permanent childhood hearing impairment: an 8-year follow-up of a controlled trial
  209. Longer term clinical and economic benefits of offering acupuncture care to patients with chronic low back pain
  210. Clinical Signals
  211. Pulmonary Medicine
  212. Time Series Regression
  213. A 24 year cohort study of mortality in slate workers in North Wales
  214. A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine
  215. Intraclass correlation coefficient and outcome prevalence are associated in clustered binary data
  216. Design of Studies for Medical Research
  217. Editorial
  218. Surrogate markers: back to the future
  219. Assurance in clinical trial design
  220. Restructuring the editorial board
  221. The use of bootstrap methods for estimating sample size and analysing health-related quality of life outcomes
  222. Outdoor Air Pollution and Stroke in Sheffield, United Kingdom: A Small-Area Level Geographical Study
  223. A survey of statistics in three UK general practice journal
  224. BMJ statistical errors
  225. Patterns of intra-cluster correlation from primary care research to inform study design and analysis
  226. Smoking and Parkinson's disease: Systematic review of prospective studies
  227. Extending CONSORT to include cluster trials
  228. Acupuncture for low back pain: traditional diagnosis and treatment of 148 patients in a clinical trial
  229. Statistical aspects
  230. Combination of APACHE-II score and an obesity score (APACHE-O) for the prediction of severe acute pancreatitis
  231. The Armitage lectures
  232. Editorial
  233. Parkinson’s Disease Protects Against Smoking?
  234. Sensitivity analysis of common statistical models used to study the short-term effects of air pollution on health
  235. Geographical and organisational variation in the structure of primary care services: implications for study design
  236. Statistics in Medicine moves into online submission
  237. Effect on endometrium of long term treatment with continuous combined oestrogen-progestogen replacement therapy: follow up study
  238. Longer-Term Clinical and Economic Benefits of Offering Acupuncture to Patients with Chronic Low Back Pain Assessed as Suitable for Primary Care Management – 3 Month Clinical Outcomes from a Controlled Trial of 241 Patients
  239. Epidemiology research
  240. Discussion on the paper by Spiegelhalter, Aylin, Best, Evans and Murray
  241. A review of ordinal regression models applied on health-related quality of life assessments
  242. La enfermedad de Parkinson y el tabaco: coherencia y plausibilidad
  243. Randomized, Controlled Trial of Acetazolamide and Furosemide in Posthemorrhagic Ventricular Dilation in Infancy: Follow-Up at 1 Year
  244. Atmospheric pressure and sudden infant death syndrome in Cook County, Chicago
  245. The Wessex Recent In-Patient Suicide Study, 2
  246. The Wessex Recent In-Patient Suicide Study, 1
  247. The Safety and Effectiveness of the Le Fort I Approach to Removing Central Skull Base Lesions
  248. Randomized controlled trial of physiotherapy in 56 children with cerebral palsy followed for 18 months
  249. DESIGN AND ANALYSIS OF TRIALS WITH QUALITY OF LIFE AS AN OUTCOME: A PRACTICAL GUIDE
  250. Preface
  251. The endometrial response to sequential and continuous combined oestrogen-progestogen replacement therapy
  252. Sample sizes for cancer trials where Health Related Quality of Life is the primary outcome
  253. The Wessex Head Injury Matrix (WHIM) main scale: a preliminary report on a scale to assess and monitor patient recovery after severe head injury
  254. Causality and temporality in the study of short-term effects of air pollution on health
  255. Cluster randomized trials in general (family) practice research
  256. Effects of a clinical-practice guideline and practice-based education on detection and outcome of depression in primary care: Hampshire Depression Project randomised controlled trial
  257. Statistical review by research ethics committees
  258. Effect of antidepressant drug counselling and information leaflets on adherence to drug treatment in primary care: randomised controlled trial
  259. Modelling influenza epidemics in the relation between black smoke and total mortality. A sensitivity analysis
  260. A GEE moving average analysis of the relationship between air pollution and mortality for asthma in Barcelona, Spain
  261. Patient centred care of diabetes in general practice
  262. Longer term clinical and economic benefits of offering acupuncture to patients with chronic low back pain assessed as suitable for primary care management
  263. ESTIMATING SAMPLE SIZES FOR CONTINUOUS, BINARY, AND ORDINAL OUTCOMES IN PAIRED COMPARISONS: PRACTICAL HINTS
  264. Diabetes Care from Diagnosis: Effects of training in patient-centred care on beliefs, attitudes and behaviour of primary care professionals
  265. Systemic effects of inhaled corticosteroids on growth and bone turnover in childhood asthma: a comparison of fluticasone with beclomethasone
  266. Controlled trial of universal neonatal screening for early identification of permanent childhood hearing impairment
  267. Choosing between randomised and non-randomised studies: a systematic review
  268. Randomised controlled trial of patient centred care of diabetes in general practice: impact on current wellbeing and future disease risk
  269. International randomised controlled trial of acetazolamide and furosemide in posthaemorrhagic ventricular dilatation in infancy
  270. Sample size calculations for paired or matched ordinal data
  271. Investigation of the effect of occult invasive cancer on progress towards successful cervical screening
  272. Clinical significance not statistical significance: a simple Bayesian alternative to p values
  273. Duration of growth suppressive effects of regular inhaled corticosteroids
  274. Trends in asthma
  275. Quality of life and patient preference for sequential versus continuous combined HRT: the UK Kliofem® multicenter study experience
  276. Association between nonadministration of subconjunctival cefuroxime and postoperative endophthalmitis
  277. Half-life of intracameral gentamicin after phacoemulsification
  278. Age specific trends in asthma mortality in England and Wales, 1983-95: results of an observational study
  279. Prevalence of inverted and non-protractile nipples in antenatal women who intend to breast-feed
  280. Circaseptennial rhythm is an artefact
  281. Women Married to Men with Myocardial Infarction are at Increased Risk of Coronary Heart Disease
  282. Double blind placebo controlled trial of nebulised budesonide for croup   Commentary
  283. Using aspects of study design in sample size estimation
  284. Does dietary intake of vitamins C and E influence lung function in older people?
  285. The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis.
  286. Spectral analysis of clinical signals: an interface between medical statisticians and medical engineers
  287. Sample sizes for studies using the short form 36 (SF-36)
  288. Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons
  289. Statistics would make Stalin proud
  290. Good long-term outcome following surgical repair of post-infarction ventricular septal defect
  291. Study quoted had flawed design
  292. Assessing the Adequacy of Standard Clinical Definitions of Important Vaginal Bleeding Disorders
  293. Posture, blood velocity in common femoral vein, and prophylaxis of venous thromboembolism
  294. P values are still useful
  295. Commentary: n of 1 trials may be useful for informed decision making
  296. Is the timing of withdrawal bleeding a guide to endometrial safety during sequential oestrogen-progestagen replacement therapy?
  297. Coping with extra poisson variability in the analysis of factors influencing vaginal ring expulsions
  298. Asthma at the interface: bridging the gap between general practice and a district general hospital.
  299. Statistics in medicine: Citations of papers in the first ten years
  300. Does clinical experience with a treatment regimen affect survival of lung cancer patients? An analysis based on consecutive randomized trials of the medical research council in small cell and non-small cell tumours
  301. Time Series Regression for Counts: An Investigation into the Relationship between Sudden Infant Death Syndrome and Environmental Temperature
  302. Sample size in audit.
  303. Determinants of contraceptive method choice after first delivery, before first abortion, and after first abortion in East China
  304. A review of behavioural assessment scales for monitoring recovery in and after coma with pilot data on a new scale of visual awareness
  305. Box-plots
  306. Management of feverish children at home.
  307. The Interaction between Immunoglobulin E and Smoking in Airflow Obstruction in the Elderly
  308. Randomised controlled trial of breast shells and Hoffman's exercises for inverted and non-protractile nipples.
  309. Effects of self-help post-myocardial-infarction rehabilitation on psychological adjustment and use of health services
  310. Adjusting for baseline: Chamge or percentage change
  311. An Evaluation of a Nurse-run Asthma Clinic in General Practice Using an Attitudes and Morbidity Questionnaire
  312. Assessment of the psychological impact of a breast screening programme
  313. Magnesium and chronic fatigue syndrome
  314. Red blood cell magnesium and chronic fatigue syndrome
  315. Coping with extra poisson variability in the analysis of factors influencing vaginal ring expulsions
  316. Sudden infant deaths and cold weather: was the rise in infant mortality in 1986 in England and Wales due to the weather?
  317. Heights and Weights of Children in Ladakh, North India
  318. Response
  319. Comparison of audible sound transmission with ultrasound in screening for congenital dislocation of the hip
  320. Prognostic index for the development of liver metastases in patients with colorectal cancer
  321. Analysis of serial measurements in medical research: Authors' reply
  322. Does anonymity increase response rate in postal questionnaire surveys about sensitive subjects? A randomised trial.
  323. Analysis of serial measurements in medical research.
  324. Sudden infant death syndrome and environmental temperature: further evidence for a time‐lagged relationship (for editorial comment, see page 361)
  325. Is there an increased risk of twinning after discontinuation of the oral contraceptive pill?
  326. Relief care and risk of death in psychogeriatric patients.
  327. Methotrexate dosage in patients aged over 50 with psoriasis.
  328. Letters to the editor
  329. Effect of transdermal glyceryl trinitrate on the survival of peripheral intravenous infusions: A double-blind prospective clinical study
  330. Exercise levels and resting pulse rate in the community.
  331. Further evidence for the effect of passive smoking on neonates.
  332. Assessing changes in vaginal bleeding patterns in contracepting women
  333. Statistics in Medicine: Calculating confidence intervals for some non-parametric analyses
  334. Twenty years' screening for cancer of the uterine cervix in Great Britain, 1964-84: further evidence for its ineffectiveness.
  335. SUGAR AND HEALTH
  336. The success of in situ vein grafting: Early results in comparison with the reversed vein technique
  337. Public knowledge about AIDS increasing.
  338. Sudden infant death syndrome and environmental temperature: an analysis using vital statistics.
  339. Predictive power of progesterone receptor status in early breast carcinoma
  340. Public knowledge of AIDS and the DHSS advertisement campaign: Authors' reply
  341. Public knowledge of AIDS and the DHSS advertisement campaign.
  342. Increased risk of sudden infant death syndrome in older infants at weekends.
  343. Specific causes of death in miners and ex-miners of the Rhondda Fach 1950-80.
  344. Gastric cancer in a south Wales valley.
  345. Respiratory disability in ex-flax workers.
  346. Use of check lists in assessing the statistical content of medical studies.
  347. A comparison of plating and traction in the treatment of tibial shaft fractures
  348. Mortality of men in the Rhondda Fach 1950-80.
  349. AZATHIOPRINE AND CYCLOSPORIN: DIFFERENT TISSUE MATCHING CRITERIA NEEDED?
  350. Multiplicative and additive models with external controls in a cohort study of cancer mortality
  351. Peer review at work
  352. Peer review at work
  353. Can general practitioners influence exercise habits? Controlled trial.
  354. Mortality, haemoglobin level and haematocrit in women
  355. Chest pain in women: a study of prevalence and mortality follow up in south Wales.
  356. Migraine, headache, and survival in women
  357. Trials of live attenuated influenza virus vaccine in patients with chronic obstructive airways disease
  358. Migraine, headache, and survival in women.
  359. HIGH BLOOD PRESSURE AND MORTALITY IN THE ELDERLY
  360. The analysis using genstat of anaemia, sugar intake and Quetelet's index as prognostic indicators in women
  361. Spectral Analysis Applied To Physiological Signals In Human Subjects
  362. IRREGULAR OPACITIES IN COALWORKERS' PNEUMOCONIOSIS—CORRELATION WITH PULMONARY FUNCTION AND PATHOLOGY
  363. Relationship between type of simple coalworkers' pneumoconiosis and lung function. A nine-year follow-up study of subjects with small rounded opacities.
  364. Aetiological factors in rickets of prematurity.
  365. Cardiac frequency during stepping exercise and during treadmill walking as guides to the Harvard Pack Index of physical fitness
  366. A note on the sampling of a point process for spectral analysis
  367. A Survey of Statistical Work on the Mackenzie River Series of Annual Canadian Lynx Trappings for the Years 1821-1934 and a New Analysis
  368. A Review of the Use of the Main Quality of Life Measures, and Sample Size Determination for Quality of Life Measures, Particularly in Cancer Clinical Trials
  369. Answers to Exercises
  370. Appendix 1: Exponentials and Logarithms
  371. Appendix 2: Maximum Likelihood and Significance Tests
  372. Appendix 3: Bootstrapping and Variance Robust Standard Errors
  373. Appendix 4: Bayesian Methods
  374. Frontmatter
  375. Glossary
  376. Index
  377. Logistic Regression
  378. Models, Tests and Data
  379. Multiple Linear Regression
  380. Other Models
  381. Random Effects Models
  382. Survival Analysis