Contact

All Stories

  1. Lymphatics can metamorphose into blood vessels

    Article • Nature Cardiovascular Research, May 2022, Springer Science + Business Media

    Dr Michael Jeltsch

  2. Is the prostate cancer marker PSA inducing or inhibiting the growth of blood and lymphatic vessels?

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Dr Michael Jeltsch

  3. PSA ac­tiv­ates growth factors that con­trib­ut­e to the spread of can­cer

    Article • eLife, May 2019, eLife

    Dr Michael Jeltsch

  4. What you need to know about VEGF-C when trying to grow lymphatics for the treatment of lymphedema

    Article • Frontiers in Bioengineering and Biotechnology, February 2018, Frontiers

    Dr Michael Jeltsch

  5. Requirements for efficient activation of vascular endothelial growth factor C

    Article • Scientific Reports, July 2017, Nature

    Khushbu Rauniyar, Dr Michael Jeltsch

  6. Factors regulating the substrate specificity of cytosolic phospholipase A2-alpha in vitro

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, November 2016, Elsevier

    Dr Michael Jeltsch

  7. How to grow lymphatic vessels

    Article • Tissue Engineering Part B Reviews, October 2016, Mary Ann Liebert Inc

    Dr Michael Jeltsch

  8. Functional Importance of a Proteoglycan Coreceptor in Pathologic LymphangiogenesisNovelty and Significance

    Article • Circulation Research, May 2016, Wolters Kluwer Health

    Dr Michael Jeltsch

  9. The relative importance of the two parts (domains) of the CCBE1 protein

    Article • Circulation Research, March 2015, Wolters Kluwer Health

    Dr Michael Jeltsch

  10. Substrate Efflux Propensity Is the Key Determinant of Ca2+-independent Phospholipase A-β (iPLAβ)-mediated Glycerophospholipid Hydrolysis

    Article • Journal of Biological Chemistry, February 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael Jeltsch

  11. The TIE Receptor Family

    Article • January 2015, Springer Science + Business Media

    Dr Michael Jeltsch

  12. CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3-Mediated Vascular Endothelial Growth Factor-C Activation

    Article • Circulation, February 2014, Wolters Kluwer Health

    Dr Michael Jeltsch

  13. Receptor Tyrosine Kinase-Mediated Angiogenesis

    Article • Cold Spring Harbor Perspectives in Biology, September 2013, Cold Spring Harbor Laboratory Press

    Dr Michael Jeltsch

  14. Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation

    Article • Proceedings of the National Academy of Sciences, July 2013, Proceedings of the National Academy of Sciences

    Dr Michael Jeltsch

  15. The Basis for the Distinct Biological Activities of Vascular Endothelial Growth Factor Receptor-1 Ligands

    Article • Science Signaling, July 2013, American Association for the Advancement of Science

    Dr Michael Jeltsch

  16. A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development

    Article • Development, March 2013, The Company of Biologists

    Dr Michael Jeltsch

  17. Vascular Endothelial Growth Factor-Angiopoietin Chimera With Improved Properties for Therapeutic Angiogenesis

    Article • Circulation, January 2013, Wolters Kluwer Health

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  18. Critical Role of VEGF-C/VEGFR-3 Signaling in Innate and Adaptive Immune Responses in Experimental Obliterative Bronchiolitis

    Article • American Journal Of Pathology, November 2012, Elsevier

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  19. Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

    Article • Blood, December 2010, American Society of Hematology

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  20. Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization

    Article • Cancer Cell, December 2010, Elsevier

    Dr Michael Jeltsch

  21. Suppressive Effects of Vascular Endothelial Growth Factor-B on Tumor Growth in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

    Article • PLoS ONE, November 2010, PLOS

    Dr Michael Jeltsch

  22. Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation

    Article • Circulation, October 2010, Wolters Kluwer Health

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  23. Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

    Article • Genes & Development, May 2010, Cold Spring Harbor Laboratory Press

    Dr Michael Jeltsch

  24. Structural determinants of growth factor binding and specificity by VEGF receptor 2

    Article • Proceedings of the National Academy of Sciences, January 2010, Proceedings of the National Academy of Sciences

    Dr Michael Jeltsch

  25. Activated Forms of VEGF-C and VEGF-D Provide Improved Vascular Function in Skeletal Muscle

    Article • Circulation Research, May 2009, Wolters Kluwer Health

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  26. Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy

    Article • Circulation Research, July 2008, Wolters Kluwer Health

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  27. The Tyrosine Kinase Inhibitor Cediranib Blocks Ligand-Induced Vascular Endothelial Growth Factor Receptor-3 Activity and Lymphangiogenesis

    Article • Cancer Research, June 2008, American Association for Cancer Research (AACR)

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  28. Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2008, Wolters Kluwer Health

    Dr Michael Jeltsch

  29. Enhanced Capillary Formation Stimulated by a Chimeric Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor-C Silk Domain Fusion Protein

    Article • Circulation Research, May 2007, Wolters Kluwer Health

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  30. Distinct Architecture of Lymphatic Vessels Induced by Chimeric Vascular Endothelial Growth Factor-C/Vascular Endothelial Growth Factor Heparin-Binding Domain Fusion Proteins

    Article • Circulation Research, May 2007, Wolters Kluwer Health

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  31. Functional interaction of VEGF-C and VEGF-D with neuropilin receptors

    Article • The FASEB Journal, July 2006, Federation of American Societies For Experimental Biology (FASEB)

    Dr Michael Jeltsch

  32. Vascular Endothelial Growth Factor (VEGF)/VEGF-C Mosaic Molecules Reveal Specificity Determinants and Feature Novel Receptor Binding Patterns

    Article • Journal of Biological Chemistry, February 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael Jeltsch

  33. Dual Role of Vascular Endothelial Growth Factor in Experimental Obliterative Bronchiolitis

    Article • American Review of Respiratory Disease, June 2005, American Thoracic Society

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  34. Vascular Endothelial Cell Growth Factor Receptor 3-Mediated Activation of Lymphatic Endothelium Is Crucial for Tumor Cell Entry and Spread via Lymphatic Vessels

    Article • Cancer Research, June 2005, American Association for Cancer Research (AACR)

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  35. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation

    Article • Journal of Clinical Investigation, January 2005, American Society for Clinical Investigation

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  36. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

    Article • Nature Immunology, November 2003, Nature

    Dr Michael Jeltsch

  37. Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function

    Article • The FASEB Journal, November 2003, Federation of American Societies For Experimental Biology (FASEB)

    Dr Michael Jeltsch

  38. Genesis and pathogenesis of lymphatic vessels

    Article • Cell and Tissue Research, October 2003, Springer Science + Business Media

    Dr Michael Jeltsch

  39. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

    Article • The Journal of Cell Biology, June 2003, Rockefeller University Press

    Dr Michael Jeltsch, Professor Christiana Ruhrberg

  40. Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes

    Article • The FASEB Journal, July 2002, Federation of American Societies For Experimental Biology (FASEB)

    Dr Seppo Yla-Herttuala, Dr Michael Jeltsch

  41. VEGFR-3 alone is sufficient for lymphangiogenesis

    Article • The EMBO Journal, March 2001, Wiley

    Dr Michael Jeltsch

  42. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

    Article • The EMBO Journal, February 2001, Wiley

    Dr Michael Jeltsch

  43. VEGF-C adenovirus gene transfer reduces intima formation in rabbits

    Article • Atherosclerosis, July 2000, Elsevier

    Dr Michael Jeltsch

  44. Current biology of VEGF-B and VEGF-C

    Article • Current Opinion in Biotechnology, December 1999, Elsevier

    Dr Michael Jeltsch

  45. Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity

    Article • Journal of Cellular Physiology, December 1998, Wiley

    Dr Michael Jeltsch

  46. Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells

    Article • Proceedings of the National Academy of Sciences, September 1998, Proceedings of the National Academy of Sciences

    Dr Michael Jeltsch

  47. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

    Article • Proceedings of the National Academy of Sciences, January 1998, Proceedings of the National Academy of Sciences

    Dr Michael Jeltsch

  48. Vascular endothelial growth factors VEGF-B and VEGF-C

    Article • Journal of Cellular Physiology, November 1997, Wiley

    Dr Michael Jeltsch

  49. Genomic Organization of Human and Mouse Genes for Vascular Endothelial Growth Factor C

    Article • Journal of Biological Chemistry, October 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael Jeltsch

  50. VEGF and VEGF-C: Specific Induction of Angiogenesis and Lymphangiogenesis in the Differentiated Avian Chorioallantoic Membrane

    Article • Developmental Biology, August 1997, Elsevier

    Dr Michael Jeltsch

  51. Proteolytic processing regulates receptor specificity and activity of VEGF-C

    Article • The EMBO Journal, July 1997, Wiley

    Dr Michael Jeltsch

  52. Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice

    Article • Science, May 1997, American Association for the Advancement of Science

    Dr Michael Jeltsch