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  1. The zlog value: a decade of standardizing laboratory results

    Article • Journal of Laboratory Medicine, August 2026, De Gruyter

    DR Matthias Orth

  2. UEMS Should Develop a Position on Direct-to-Consumer Testing (DTCT): Point of view

    Article • European Medical Specialist Review, August 2026, European Union of Medical Specialists

    DR Matthias Orth

  3. Intact Parathyroid Hormone Reference Intervals: Importance of Pre-Processing for Indirect Reference Interval Estimation

    Article • Diagnostics, July 2026, MDPI AG

    DR Matthias Orth

  4. EFLM position statement on the proposed 2025/0404(COD) IVDR Amendment of Article 5.5

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), May 2026, De Gruyter

    DR Matthias Orth

  5. Estimation of Sex- and Age-Specific Reference Values for Serum Creatinine Using Three Indirect Methods in a Multicenter Setting

    Article • The Journal of Applied Laboratory Medicine, March 2026, Oxford University Press (OUP)

    DR Matthias Orth

  6. Supporting trend detection in the cumulative display of electronic laboratory reports from multiple laboratories while preserving measurement provenance

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), September 2025, De Gruyter

    DR Matthias Orth

  7. Direct-to-Consumer Testing: Benefits and Concerns of Commercially Accessed Laboratory Tests

    Article • Clinical Chemistry, February 2025, Oxford University Press (OUP)

    DR Matthias Orth

  8. Abstracts from the 29th ADLM International CPOCT Symposium: Quality Beyond the Lab: Navigating POCT Excellence in Patient Care

    Article • The Journal of Applied Laboratory Medicine, February 2025, Oxford University Press (OUP)

    DR Matthias Orth

  9. Erratum: Buttini et al., “Expression of Human Apolipoprotein E3 or E4 in the Brains ofApoe−/−Mice: Isoform-Specific Effects on Neurodegeneration”

    Article • Journal of Neuroscience, January 2025, Society for Neuroscience

    DR Matthias Orth

  10. Comparison of three indirect methods for verification and validation of reference intervals at eight medical laboratories: a European multicenter study

    Article • Journal of Laboratory Medicine, June 2023, De Gruyter

    DR Matthias Orth

  11. Direct to Consumer Testing (DTCT)

    Article • Trillium Diagnostik, March 2023, Trillium GmbH Medizinischer Fachverlag

    DR Matthias Orth

  12. LOINC und zlog

    Article • Trillium Diagnostik, March 2023, Trillium GmbH Medizinischer Fachverlag

    DR Matthias Orth

  13. ISO 15189 is a sufficient instrument to guarantee high-quality manufacture of laboratory developed tests for in-house-use conform requirements of the European In-Vitro-Diagnostics Regulation

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2023, De Gruyter

    DR Matthias Orth, Prof Dr em MD PhD EuSpLM Florent JLA Vanstapel

  14. Direct-to-consumer laboratory testing (DTCT): challenges and implications for specialists in laboratory medicine

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), December 2022, De Gruyter

    DR Matthias Orth

  15. M145 Serum lipase testing on the Abbott alinity: Indirect reference range estimation reveals differences between diasys and sentinel reagents

    Article • Clinica Chimica Acta, May 2022, Elsevier

    DR Matthias Orth

  16. To discriminate or not to discriminate

    Article • Trillium Diagnostik, December 2021, Trillium GmbH Medizinischer Fachverlag

    DR Matthias Orth

  17. Implementation of the new EU IVD regulation – urgent initiatives are needed to avert impending crisis

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), September 2021, De Gruyter

    Prof Christa CM Cobbaert, DR Matthias Orth, Prof Dr em MD PhD EuSpLM Florent JLA Vanstapel

  18. Requirements for electronic laboratory reports according to the German guideline Rili-BAEK and ISO 15189

    Article • Journal of Laboratory Medicine, July 2021, De Gruyter

    DR Matthias Orth

  19. Treatment with Ceftriaxone in Complicated Diverticulitis Increases the Incidence of Intra-Abdominal Enterococcus faecium Detection

    Article • Surgical Infections, June 2021, Mary Ann Liebert Inc

    DR Matthias Orth

  20. Age and sex dependent reference intervals for random plasma/serum glucose concentrations related to different sampling devices and determined by an indirect procedure with data mining

    Article • Journal of Laboratory Medicine, September 2020, De Gruyter

    DR Matthias Orth

  21. Up-to date platelet testing

    Article • LaboratoriumsMedizin, September 2020, De Gruyter

    DR Matthias Orth

  22. Diagnostic work up of anemic patients: role of iron deficiency

    Article • LaboratoriumsMedizin, August 2020, De Gruyter

    DR Matthias Orth

  23. Quantitative laboratory results: normal or lognormal distribution?

    Article • Journal of Laboratory Medicine, June 2020, De Gruyter

    DR Matthias Orth

  24. How do different tube types effect diabetes prevalence?

    Article • Practical Laboratory Medicine, November 2019, Elsevier

    DR Matthias Orth

  25. Autoverication is useful to improve the quality of laboratory testing

    Article • Clinical Biochemistry, November 2019, Elsevier

    DR Matthias Orth

  26. long-term storage of patient and consumer test results

    Article • LaboratoriumsMedizin, December 2018, De Gruyter

    DR Matthias Orth

  27. Commutability Assessment of Candidate Reference Materials for Pancreatic Alpha-amylase

    Article • Clinical Chemistry, August 2018, Oxford University Press (OUP)

    DR Matthias Orth

  28. color coding of laboratory test results

    Article • LaboratoriumsMedizin, April 2018, De Gruyter

    DR Matthias Orth

  29. Opinion: redefining the role of the physician in laboratory medicine in the context of emerging technologies, personalised medicine and patient autonomy (‘4P medicine’)

    Article • Journal of Clinical Pathology, December 2017, BMJ

    DR Matthias Orth

  30. guidelines for blood drawing (peripheral vein)

    Article • LaboratoriumsMedizin, December 2017, De Gruyter

    DR Matthias Orth

  31. Biomarker Troponin (2): Sicht des Labormediziners

    Article • Deutsches Ärzteblatt Online, November 2017, Deutscher Arzte-Verlag GmbH

    DR Matthias Orth

  32. Direct-to-Consumer Testing: the business with lifestyle tests

    Article • Point of Care The Journal of Near-Patient Testing & Technology, September 2017, Wolters Kluwer Health

    DR Matthias Orth

  33. The use of error and uncertainty methods in the medical laboratory

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), August 2017, De Gruyter

    DR Matthias Orth, Hassane Bayat

  34. Schnelltests: Mit Bedacht einsetzen

    Article • Deutsches Ärzteblatt Online, April 2017, Deutscher Arzte-Verlag GmbH

    DR Matthias Orth

  35. Der zlog-Wert als Basis für die Standardisierung von Laborwerten

    Article • LaboratoriumsMedizin, February 2017, De Gruyter

    DR Matthias Orth

  36. Festlegung der zulässigen Messunsicherheit quantitativer Messgrößen in der Laboratoriumsmedizin

    Article • LaboratoriumsMedizin, January 2017, De Gruyter

    DR Matthias Orth

  37. The zlog value as a basis for the standardization of laboratory results

    Article • LaboratoriumsMedizin, January 2017, De Gruyter

    DR Matthias Orth

  38. Chancen und Risiken von e-Health in der Labormedizin

    Article • LaboratoriumsMedizin, August 2016, De Gruyter

    DR Matthias Orth

  39. Corrigendum zu: Chancen und Risiken von e-Health in der Labormedizin

    Article • LaboratoriumsMedizin, January 2016, De Gruyter

    DR Matthias Orth

  40. Recommendations for the frequency of ordering laboratory testing

    Article • LaboratoriumsMedizin, January 2015, De Gruyter

    DR Matthias Orth

  41. Are regulation-driven performance criteria still acceptable? – The German point of view

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2015, De Gruyter

    DR Matthias Orth

  42. Multicenter Analytical Evaluation of the Automated Electrochemiluminescence Immunoassay for Cyclosporine

    Article • Therapeutic Drug Monitoring, October 2014, Wolters Kluwer Health

    DR Matthias Orth

  43. Multi-center analytical evaluation of a novel automated tacrolimus immunoassay

    Article • Clinical Biochemistry, August 2014, Elsevier

    DR Matthias Orth

  44. Comparability and Imprecision of 8 Frequently Used Commercially Available Immunoassays for Therapeutic Drug Monitoring

    Article • Therapeutic Drug Monitoring, August 2014, Wolters Kluwer Health

    DR Matthias Orth

  45. Empfehlungen zur Häufigkeit der Anforderung von Laboruntersuchungen

    Article • LaboratoriumsMedizin, January 2014, De Gruyter

    DR Matthias Orth

  46. Umfrage zur Laborberatung in Deutschland

    Article • LaboratoriumsMedizin, January 2014, De Gruyter

    DR Matthias Orth

  47. Key figures and benchmarking in the hospital laboratory1)

    Article • LaboratoriumsMedizin, January 2013, De Gruyter

    DR Matthias Orth

  48. Pros and cons of thrombophilia testing1)

    Article • LaboratoriumsMedizin, January 2013, De Gruyter

    DR Matthias Orth

  49. Pro und Contra der Thrombophiliediagnostik/Pros and cons of thrombophilia testing

    Article • LaboratoriumsMedizin, January 2013, De Gruyter

    DR Matthias Orth

  50. Prevention of CA-MRSA

    Article • Deutsches Ärzteblatt international, April 2012, Deutscher Arzte-Verlag GmbH

    DR Matthias Orth

  51. Update of D-dimer testing1)

    Article • LaboratoriumsMedizin, January 2012, De Gruyter

    DR Matthias Orth

  52. Einsatz der D-Dimerbestimmung – ein Update/Update of D-dimer testing

    Article • LaboratoriumsMedizin, January 2012, De Gruyter

    DR Matthias Orth

  53. Kennzahlen und Benchmarking im Krankenhauslabor/Key figures and benchmarking in the hospital laboratory

    Article • LaboratoriumsMedizin, January 2012, De Gruyter

    DR Matthias Orth

  54. HE4 in gynecological cancers: report of a European investigators and experts meeting

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2012, De Gruyter

    DR Matthias Orth

  55. Cholesterol: Its Regulation and Role in Central Nervous System Disorders

    Article • Cholesterol, January 2012, Hindawi Publishing Corporation

    DR Matthias Orth

  56. Unsatisfactory Quality

    Article • Deutsches Ärzteblatt international, February 2011, Deutscher Arzte-Verlag GmbH

    DR Matthias Orth

  57. Quality in Laboratory Hemostasis and Thrombosis

    Article • LaboratoriumsMedizin, January 2011, De Gruyter

    DR Matthias Orth

  58. Antibiotika am Krankenbett

    Article • LaboratoriumsMedizin, January 2011, De Gruyter

    DR Matthias Orth

  59. Praktische Umsetzung des Gendiagnostikgesetzes (GenDG) in der Laboratoriumsmedizin, dem humangenetischen Laboratorium und der humangenetischen Beratung/Practical Implications of the German Genetic Diagnostics Act (GenDG) for Laboratory Medicine, the Hu...

    Article • LaboratoriumsMedizin, January 2011, De Gruyter

    DR Matthias Orth

  60. CSF interleukin 6 – a useful biomarker of meningitis in adults?/Liquor Interleukin 6 – ein sinnvoller Biomarker für die Meningitis beim Erwachsenen

    Article • LaboratoriumsMedizin, January 2011, De Gruyter

    DR Matthias Orth

  61. Quintessence Unjustified

    Article • Deutsches Ärzteblatt international, March 2010, Deutscher Arzte-Verlag GmbH

    DR Matthias Orth, Professor Jutta Dierkes

  62. Antiplatelet drugs in cardiology: current trends in therapy and monitoring 1

    Article • LaboratoriumsMedizin, January 2010, De Gruyter

    DR Matthias Orth

  63. Thrombozytenhemmende Therapie in der Kardiologie: aktuelle Entwicklungen bei Therapie und Monitoring / Antiplatelet drugs in cardiology: current trends in therapy and monitoring

    Article • LaboratoriumsMedizin, January 2010, De Gruyter

    DR Matthias Orth

  64. Factor II- and factor Xa-inhibitors for prevention and treatment of thromboses / Faktor II- und Faktor Xa-Inhibitoren in der Prävention und Therapie von Thrombosen

    Article • LaboratoriumsMedizin, March 2009, De Gruyter

    DR Matthias Orth

  65. Benigne Prostata‐Hyperplasie und Benignes Prostata‐Syndrom. Die Krankheit des alten Mannes

    Article • Pharmazie in unserer Zeit, July 2008, Wiley

    DR Matthias Orth

  66. Langzeittherapie der familiären Hypercholesterinämie mit Heparin-induzierter extrakorporaler LDL-Präzipitation

    Article • DMW - Deutsche Medizinische Wochenschrift, March 2008, Thieme Publishing Group

    DR Matthias Orth

  67. Cytokines in the Genesis and Treatment of Cancer

    Article • LaboratoriumsMedizin, January 2008, De Gruyter

    DR Matthias Orth

  68. cAMP-induced expression of ABCA1 is associated with MAP-kinase-pathway activation

    Article • Biochemical and Biophysical Research Communications, November 2007, Elsevier

    DR Matthias Orth

  69. Endocytosis and intracellular trafficking of fatty acid esters of phenylaminopropanediol, the putative etiologic agents of the toxic oil syndrome (TOS)

    Article • Toxicology Letters, June 2006, Elsevier

    DR Matthias Orth

  70. Activity of sirolimus in patients with myelodysplastic syndrome - results of a pilot study

    Article • British Journal of Haematology, March 2005, Wiley

    DR Matthias Orth, Christian Thiede

  71. Thrombophiliediagnostik bei Empfängern von Organtransplantaten / Thrombophilia diagnostics in recipients of organ transplants

    Article • LaboratoriumsMedizin, January 2004, De Gruyter

    DR Matthias Orth

  72. A New Concept for Acne Therapy: A Pilot Study With Zileuton, an Oral 5-Lipoxygenase Inhibitor

    Article • Archives of Dermatology, May 2003, American Medical Association (AMA)

    DR Matthias Orth

  73. Chylomicron Remnant Concentrations in Patients with Coronary Artery Disease

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2003, De Gruyter

    DR Matthias Orth

  74. Shed L-Selectin (sCD62L) Load in Trauma Patients

    Article • Journal of Surgical Research, August 2001, Elsevier

    DR Matthias Orth

  75. An improved method for the rapid assessment of persisting chylomicron remnant concentrations

    Article • Clinical Biochemistry, July 2001, Elsevier

    DR Matthias Orth

  76. Postprandial chylomicrons and VLDLs in severe hypertriacylglycerolemia are lowered more effectively than are chylomicron remnants after treatment with n−3 fatty acids

    Article • American Journal of Clinical Nutrition, April 2000, Oxford University Press (OUP)

    DR Matthias Orth

  77. Expression of Human Apolipoprotein E3 or E4 in the Brains ofApoe−/−Mice: Isoform-Specific Effects on Neurodegeneration

    Article • Journal of Neuroscience, June 1999, Society for Neuroscience

    DR Matthias Orth

  78. Hemostatic Factors in Hypertriglyceridemic Men

    Article • Thrombosis Research, June 1999, Elsevier

    DR Matthias Orth

  79. Effects of a Frequent Apolipoprotein E Isoform, ApoE4Freiburg (Leu28->Pro), on Lipoproteins and the Prevalence of Coronary Artery Disease in Whites

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 1999, Wolters Kluwer Health

    DR Matthias Orth

  80. Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: Increased susceptibility of females

    Article • Proceedings of the National Academy of Sciences, September 1998, Proceedings of the National Academy of Sciences

    DR Matthias Orth

  81. The Diagnostic Value of Serum Homocysteine Concentration as a Risk Factor for Coronary Artery Disease

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 1998, De Gruyter

    DR Matthias Orth

  82. Diagnostic Pitfalls during Therapy for Extreme Hypertriglyceridaemia

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 1997, De Gruyter

    DR Matthias Orth

  83. Clearance of postprandial lipoproteins in normolipemics: role of the apolipoprotein E phenotype

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, September 1996, Elsevier

    DR Matthias Orth

  84. Stable Expression and Secretion of Apolipoproteins E3 and E4 in Mouse Neuroblastoma Cells Produces Differential Effects on Neurite Outgrowth

    Article • Journal of Biological Chemistry, November 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    DR Matthias Orth

  85. Responsiveness of ATIII and coagulation factors V and VII to a standardized oral fat load

    Article • Thrombosis Research, November 1995, Elsevier

    DR Matthias Orth

  86. Effects of VLDL, chylomicrons, and chylomicron remnants on platelet aggregability

    Article • Thrombosis Research, August 1995, Elsevier

    DR Matthias Orth

  87. Apo E and apo CIII from different lipoproteins in the HDL size range and behave differently in secondary dyslipoproteinemias

    Article • Atherosclerosis, June 1995, Elsevier

    DR Matthias Orth

  88. Lack of interference of apo(a) polymorphism in nephelometric LP(a) determination

    Article • Atherosclerosis, June 1995, Elsevier

    DR Matthias Orth

  89. Late chylomicron remants after a standardized oral fat load do not discriminate between patients with coronary heart disease and healthy controls

    Article • Atherosclerosis, June 1995, Elsevier

    DR Matthias Orth

  90. Postprandial heparin-induced free fatty acids discriminate between patients with and without coronary artery disease

    Article • Atherosclerosis, June 1995, Elsevier

    DR Matthias Orth

  91. Gemfibrozil exerts favorable trends on parameters of glucose tolerance in hyperlipidemic patients suffering from diabetes mellitus

    Article • Atherosclerosis, September 1994, Elsevier

    DR Matthias Orth

  92. Pravastatin treatment decreases postprandial levels of chylomicron remnants in type IIb patients

    Article • Atherosclerosis, September 1994, Elsevier

    DR Matthias Orth

  93. The role of the liver in postprandial hypertriglyceridaemia

    Article • January 1993, Springer Science + Business Media

    DR Matthias Orth

  94. Human serum gangliosides in hypercholesterolemia, before and after extracorporeal elimination of LDL

    Article • Atherosclerosis, June 1992, Elsevier

    DR Matthias Orth

  95. Altered concentrations, patterns and distribution in lipoproteins of serum gangliosides in liver diseases of different etiologies

    Article • Journal of Hepatology, November 1990, Elsevier

    DR Matthias Orth

  96. Gangliosides in normal human serum. Concentration, pattern and transport by lipoproteins

    Article • European Journal of Biochemistry, May 1989, Wiley

    DR Matthias Orth

  97. Biosynthesis and secretion of gangliosides by the isolated perfused rat liver

    Article • Journal of Hepatology, January 1989, Elsevier

    DR Matthias Orth