All Stories

  1. Chemically and Mechanically Controlled Single-Molecule Switches Using Spiropyrans

    Article • ACS Applied Materials & Interfaces, September 2019, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  2. Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi

    Article • ACS Medicinal Chemistry Letters, September 2019, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  3. Total Synthesis of the Antimalarial Ascidian Natural Product Albopunctatone

    Article • Organic Letters, July 2019, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott, Associate Professor Nicholas West

  4. Carbon-Rich Trinuclear Octamethylferrocenophanes

    Article • Inorganic Chemistry, March 2019, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  5. Confirmation of the Revised Structure of Samoquasine A and a Proposed Structural Revision of Cherimoline

    Article • Journal of Natural Products, July 2018, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  6. Antiproliferative activity of the Antrodia camphorata secondary metabolite 4,7-dimethoxy-5-methylbenzo[ d ][1,3]dioxole and analogues

    Article • Fitoterapia, November 2017, Elsevier

    Associate Professor Matthew J Piggott

  7. What Is the Structure of the Antitubercular Natural Product Eucapsitrione?

    Article • The Journal of Organic Chemistry, July 2017, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  8. Focus on O-phosphohydroxylysine, O-phosphohydroxyproline, N 1-phosphotryptophan and S-phosphocysteine

    Article • Amino Acids, June 2017, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  9. Limiting the Hydrolysis and Oxidation of Maleimide–Peptide Adducts Improves Detection of Protein Thiol Oxidation

    Article • Journal of Proteome Research, April 2017, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  10. Occurrence and significance of phytanyl arenes across the Permian-Triassic boundary interval

    Article • Organic Geochemistry, February 2017, Elsevier

    Associate Professor Matthew J Piggott

  11. Control over cyclisation sequences of 1,1′-bifunctional octamethylferrocenes to ferrocenophanes

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Associate Professor Matthew J Piggott

  12. Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

    Article • Journal of Medicinal Chemistry, November 2016, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  13. Access to 1,2,3,4-Tetraoxygenated Benzenes via a Double Baeyer–Villiger Reaction of Quinizarin Dimethyl Ether: Application to the Synthesis of Bioactive Natural Products fromAntrodia camphorata

    Article • The Journal of Organic Chemistry, April 2016, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  14. 1,1′-Diacetyloctamethylferrocene: an overlooked and overdue synthon leading to the facile synthesis of an octamethylferrocenophane

    Article • Dalton Transactions, January 2016, Royal Society of Chemistry

    Associate Professor Matthew J Piggott

  15. Enhanced bi-stability in a ruthenium alkynyl spiropyran complex

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Professor George A Koutsantonis, Associate Professor Matthew J Piggott

  16. UWA-121, a mixed dopamine and serotonin re-uptake inhibitor, enhances l-DOPA anti-parkinsonian action without worsening dyskinesia or psychosis-like behaviours in the MPTP-lesioned common marmoset

    Article • Neuropharmacology, July 2014, Elsevier

    Associate Professor Matthew J Piggott

  17. A Four-Step Total Synthesis of Radermachol

    Article • Organic Letters, April 2014, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  18. Ethynylbenzenoid metabolites of Antrodia camphorata: synthesis and inhibition of TNF expression

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Associate Professor Matthew J Piggott

  19. Total synthesis of monosporascone and dihydromonosporascone

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Associate Professor Matthew J Piggott

  20. Panning for phosphohistidine

    Article • Nature Chemical Biology, May 2013, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  21. Bisannulation of 2,3-Dichloro-1,4-naphthoquinone witho-Nitrophenylacetic Acid Derivatives: A Succinct Synthesis of the ABCD Ring System of Alpkinidine

    Article • European Journal of Organic Chemistry, April 2013, Wiley

    Associate Professor Matthew J Piggott

  22. The Monoamine Re-Uptake Inhibitor UWA-101 Improves Motor Fluctuations in the MPTP-Lesioned Common Marmoset

    Article • PLoS ONE, September 2012, PLOS

    Associate Professor Matthew J Piggott

  23. A novel MDMA analogue, UWA-101, that lacks psychoactivity and cytotoxicity, enhances L-DOPA benefit in parkinsonian primates

    Article • The FASEB Journal, February 2012, Federation of American Societies For Experimental Biology (FASEB)

    Associate Professor Matthew J Piggott

  24. Stable triazolylphosphonate analogues of phosphohistidine

    Article • Amino Acids, November 2011, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  25. Enhancing the anti-lymphoma potential of 3,4-methylenedioxymethamphetamine (‘ecstasy’) through iterative chemical redesign: mechanisms and pathways to cell death

    Article • Investigational New Drugs, August 2011, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  26. Burning vegetation produces cyanohydrins that liberate cyanide and stimulate seed germination

    Article • Nature Communications, June 2011, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  27. Is 2,3,4,5-Tetramethoxybenzoyl Chloride a Natural Product?

    Article • Journal of Natural Products, May 2011, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  28. Characterization of 3,4-Methylenedioxymethamphetamine (MDMA) Enantiomers In Vitro and in the MPTP-Lesioned Primate: R-MDMA Reduces Severity of Dyskinesia, Whereas S-MDMA Extends Duration of ON-Time

    Article • Journal of Neuroscience, May 2011, Society for Neuroscience

    Associate Professor Matthew J Piggott

  29. Focus on phosphoaspartate and phosphoglutamate

    Article • Amino Acids, September 2010, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  30. The α2 adrenergic antagonist fipamezole improves quality of levodopa action in Parkinsonian primates

    Article • Movement Disorders, September 2010, Wiley

    Associate Professor Matthew J Piggott

  31. Reduction of l-DOPA-Induced Dyskinesia by the Selective Metabotropic Glutamate Receptor 5 Antagonist 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease

    Article • Journal of Pharmacology and Experimental Therapeutics, March 2010, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Associate Professor Matthew J Piggott

  32. Making Mixtures to Solve Structures: Structural Elucidation via Combinatorial Synthesis

    Article • Journal of Combinatorial Chemistry, January 2010, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  33. Redesigning the designer drug ecstasy: non-psychoactive MDMA analogues exhibiting Burkitt's lymphoma cytotoxicity

    Article • MedChemComm, January 2010, Royal Society of Chemistry

    Associate Professor Matthew J Piggott

  34. Physical and crystallographic characterisation of the mGlu5 antagonist MTEP and its monohydrochloride

    Article • Journal of Pharmaceutical Sciences, January 2010, Elsevier

    Professor Mark A Spackman, Associate Professor Matthew J Piggott

  35. An Expeditious Synthesis of Iminosugars

    Article • Australian Journal of Chemistry, January 2010, CSIRO Publishing

    Associate Professor Matthew J Piggott

  36. Focus on Phosphoarginine and Phospholysine

    Article • Current Protein and Peptide Science, December 2009, Bentham Science Publishers

    Associate Professor Matthew J Piggott

  37. Use of pifithrin to inhibit p53-mediated signalling of TNF in dystrophic muscles of mdx mice

    Article • Molecular and Cellular Biochemistry, October 2009, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  38. Structural identification and mass spectral interpretation of C3n highly branched alkanes in sediment and aquatic extracts and evidence for their anthropogenic origin

    Article • Organic Geochemistry, October 2009, Elsevier

    Associate Professor Matthew J Piggott

  39. Analysis of trimethyl carboxyphosphate by gas chromatography–mass spectrometry

    Article • Analytical Biochemistry, May 2008, Elsevier

    Associate Professor Matthew J Piggott

  40. Synthesis of Kalasinamide, a Putative Plant Defense Phototoxin

    Article • Journal of Natural Products, May 2008, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  41. Insights into the mechanism and regulation of pyruvate carboxylase by characterisation of a biotin-deficient mutant of the Bacillus thermodenitrificans enzyme

    Article • The International Journal of Biochemistry & Cell Biology, January 2008, Elsevier

    Associate Professor Matthew J Piggott

  42. Progress toward a Rationally Designed, Chemically Powered Rotary Molecular Motor

    Article • Journal of the American Chemical Society, January 2007, American Chemical Society (ACS)

    Associate Professor Matthew J Piggott

  43. Focus on phosphohistidine

    Article • Amino Acids, November 2006, Springer Science + Business Media

    Associate Professor Matthew J Piggott

  44. Synthesis of 5,8-dimethoxynaphtho[2,3-c]furan-4(9H)-one

    Article • Tetrahedron, April 2006, Elsevier

    Associate Professor Matthew J Piggott

  45. Naphtho[2,3-c]furan-4,9-diones and related compounds: theoretically interesting and bioactive natural and synthetic products

    Article • Tetrahedron, October 2005, Elsevier

    Associate Professor Matthew J Piggott

  46. Crystal Structure of 1-Methyl-5,8-dihydroxynaphtho[2,3-c]furan-4,9-dione

    Article • Australian Journal of Chemistry, January 2005, CSIRO Publishing

    Associate Professor Matthew J Piggott

  47. The Synthesis of 5-Hydroxy-3-methylnaphtho[2,3-c]furan-4,9-dione and 5,8-Dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione

    Article • Australian Journal of Chemistry, January 2003, CSIRO Publishing

    Associate Professor Matthew J Piggott

  48. The Synthesis of Ventilone A

    Article • Australian Journal of Chemistry, January 2000, CSIRO Publishing

    Associate Professor Matthew J Piggott

  49. Some Cycloaddition Reactions of 5,8-Dimethoxynaphtho[2,3-c]furan-4,9-dione

    Article • Australian Journal of Chemistry, January 1998, CSIRO Publishing

    Associate Professor Matthew J Piggott

  50. Western Australian Sandalwood Oil: Extraction by Different Techniques and Variations of the Major Components in Different Sections of a Single Tree

    Article • Flavour and Fragrance Journal, January 1997, Wiley

    Associate Professor Matthew J Piggott