All Stories

  1. The fadXDEBA locus of Staphylococcus aureus is required for metabolism of exogenous palmitic acid and in vivo growth

    Article • Molecular Microbiology, July 2023, Wiley

    Dr Martin J McGavin

  2. Repeated Emergence of Variant TetR Family Regulator, FarR, and Increased Resistance to Antimicrobial Unsaturated Fatty Acid among Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus

    Article • Antimicrobial Agents and Chemotherapy, February 2023, ASM Journals

    Dr Martin J McGavin

  3. Novel Functions and Signaling Specificity for the GraS Sensor Kinase of Staphylococcus aureus in Response to Acidic pH

    Article • Journal of Bacteriology, August 2020, ASM Journals

    Dr Martin J McGavin, Dr Ruud Veldhuizen

  4. Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA

    Article • Nature Chemical Biology, November 2019, Springer Science + Business Media

    Dr Martin J McGavin

  5. Stress-induced inactivation of the Staphylococcus aureus purine biosynthesis repressor leads to hypervirulence

    Article • Nature Communications, February 2019, Springer Science + Business Media

    Dr Martin J McGavin

  6. DNA Binding and Sensor Specificity of FarR, a Novel TetR Family Regulator Required for Induction of the Fatty Acid Efflux Pump FarE in Staphylococcus aureus

    Article • Journal of Bacteriology, November 2018, ASM Journals

    Dr Martin J McGavin

  7. Staphylococcus aureus Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages

    Article • mBio, July 2018, ASM Journals

    Dr Martin J McGavin

  8. Inducible Expression of a Resistance-Nodulation-Division-Type Efflux Pump in Staphylococcus aureus Provides Resistance to Linoleic and Arachidonic Acids

    Article • Journal of Bacteriology, March 2015, ASM Journals

    Dr Martin J McGavin, Dr David E Heinrichs

  9. Staphylococcus aureus keratinocyte invasion is mediated by integrin‐linked kinase and Rac1

    Article • The FASEB Journal, November 2014, Wiley

    Dr Martin J McGavin

  10. Role of Lipase from Community-Associated Methicillin-Resistant Staphylococcus aureus Strain USA300 in Hydrolyzing Triglycerides into Growth-Inhibitory Free Fatty Acids

    Article • Journal of Bacteriology, September 2014, ASM Journals

    Dr David E Heinrichs, Dr Martin J McGavin

  11. Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

    Article • Nature, October 2013, Springer Science + Business Media

    Dr Martin J McGavin

  12. Induction of the Staphylococcal Proteolytic Cascade by Antimicrobial Fatty Acids in Community Acquired Methicillin Resistant Staphylococcus aureus

    Article • PLoS ONE, September 2012, PLOS

    Dr David E Heinrichs, Dr Martin J McGavin

  13. The Staphylococci and Staphylococcal Pathogenesis

    Article • Frontiers in Cellular and Infection Microbiology, January 2012, Frontiers

    Dr David E Heinrichs, Dr Martin J McGavin

  14. Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30

    Article • Frontiers in Cellular and Infection Microbiology, January 2012, Frontiers

    Dr Martin J McGavin

  15. Molecular differentiation of historic phage-type 80/81 and contemporary epidemic Staphylococcus aureus

    Article • Proceedings of the National Academy of Sciences, October 2011, Proceedings of the National Academy of Sciences

    Dr Martin J McGavin

  16. Colonization with community-acquired methicillin-resistant Staphylococcus aureus in children with atopic dermatitis: a cross-sectional study

    Article • International Journal of Dermatology, May 2011, Wiley

    Dr Martin J McGavin

  17. Identification of major clonal complexes and toxin producing strains among Staphylococcus aureus associated with atopic dermatitis

    Article • Microbes and Infection, February 2011, Elsevier

    Dr Martin J McGavin

  18. Impact of accessory gene regulator (agr) dysfunction on vancomycin pharmacodynamics among Canadian community and health-care associated methicillin-resistant Staphylococcus aureus

    Article • Annals of Clinical Microbiology and Antimicrobials, January 2011, Springer Science + Business Media

    Dr Martin J McGavin

  19. Comparison of Staphopain A (ScpA) and B (SspB) precursor activation mechanisms reveals unique secretion kinetics of proSspB (Staphopain B), and a different interaction with its cognate Staphostatin, SspC

    Article • Molecular Microbiology, January 2010, Wiley

    Dr Martin J McGavin

  20. Rapid autocatalytic activation of the M4 metalloprotease aureolysin is controlled by a conserved N-terminal fungalysin-thermolysin-propeptide domain

    Article • Molecular Microbiology, September 2008, Wiley

    Dr Martin J McGavin

  21. Activation of the SspA Serine Protease Zymogen of Staphylococcus aureus Proceeds through Unique Variations of a Trypsinogen-like Mechanism and Is Dependent on Both Autocatalytic and Metalloprotease-specific Processing

    Article • Journal of Biological Chemistry, October 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Martin J McGavin

  22. Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection

    Article • Cellular Microbiology, May 2007, Wiley

    Dr Martin J McGavin

  23. Identification of different clonal complexes and diverse amino acid substitutions in penicillin-binding protein 2 (PBP2) associated with borderline oxacillin resistance in Canadian Staphylococcus aureus isolates

    Article • Journal of Medical Microbiology, December 2006, Society for General Microbiology

    Dr Martin J McGavin

  24. Interaction of Staphylococcus aureus Fibronectin-binding Protein with Fibronectin: AFFINITY, STOICHIOMETRY, AND MODULAR REQUIREMENTS

    Article • Journal of Biological Chemistry, August 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Martin J McGavin

  25. Identification of a Novel Maturation Mechanism and Restricted Substrate Specificity for the SspB Cysteine Protease ofStaphylococcus aureus

    Article • Journal of Biological Chemistry, August 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Martin J McGavin

  26. Adhesion and Virulence Properties of Epidemic Canadian Methicillin‐Resistant Staphylococcus aureus Strain 1: Identification of Novel Adhesion Functions Associated with Plasmin‐Sensitive Surface Protein

    Article • The Journal of Infectious Diseases, May 2002, Oxford University Press (OUP)

    Dr Martin J McGavin

  27. Variance in Fibronectin Binding andfnb Locus Polymorphisms in Staphylococcus aureus: Identification of Antigenic Variation in a Fibronectin Binding Protein Adhesin of the Epidemic CMRSA-1 Strain of Methicillin-Resistant S. aureus

    Article • Infection and Immunity, June 2001, ASM Journals

    Dr Martin J McGavin

  28. Description of Staphylococcus Serine Protease (ssp) Operon in Staphylococcus aureus and Nonpolar Inactivation of sspA-Encoded Serine Protease

    Article • Infection and Immunity, January 2001, ASM Journals

    Dr Martin J McGavin

  29. Synthetic Peptide Immunogens Elicit Polyclonal and Monoclonal Antibodies Specific for Linear Epitopes in the D Motifs ofStaphylococcus aureus Fibronectin-Binding Protein, Which Are Composed of Amino Acids That Are Essential for Fibronectin Binding

    Article • Infection and Immunity, March 2000, ASM Journals

    Dr Martin J McGavin

  30. Molecular Analysis of the Accessory Gene Regulator (agr) Locus and Balance of Virulence Factor Expression in Epidemic Methicillin‐Resistant Staphylococcus aureus

    Article • The Journal of Infectious Diseases, March 2000, Oxford University Press (OUP)

    Dr Martin J McGavin

  31. MSCRAMM-Mediated Adherence of Microorganisms to Host Tissues

    Article • Annual Review of Microbiology, October 1994, Annual Reviews

    Dr Martin J McGavin

  32. Two different genes coding for fibronectin-binding proteins from Streptococcus dysgalactiae. The complete nucleotide sequences and characterization of the binding domains

    Article • European Journal of Biochemistry, June 1993, Wiley

    Dr Martin J McGavin

  33. Interactions of bacteria with extracellular matrix proteins

    Article • Cell Differentiation and Development, December 1990, Elsevier

    Dr Martin J McGavin

  34. Genome Comparisons of Diverse Staphylococcus aureus Strains

    Article • Springer Science + Business Media

    Dr Martin J McGavin