All Stories

  1. Virgin β-Cells at the Neogenic Niche Proliferate Normally and Mature Slowly

    Article • Diabetes, February 2021, American Diabetes Association

    Professor Mark O. Huising

  2. Navigating the Depths and Avoiding the Shallows of Pancreatic Islet Cell Transcriptomes

    Article • Diabetes, June 2019, American Diabetes Association

    Professor Mark O. Huising, Dr. Alex M Mawla

  3. Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion

    Article • Nature Network Boston, June 2015, Springer Science + Business Media

    Professor Mark O. Huising

  4. Tuning to the right signal

    Article • Diabetologia, March 2015, Springer Science + Business Media

    Professor Mark O. Huising

  5. Role of transcription factors in the transdifferentiation of pancreatic islet cells

    Article • February 2015, Bioscientifica

    Professor Mark O. Huising

  6. Data-Driven Synthesis of Proteolysis-Resistant Peptide Hormones

    Article • Journal of the American Chemical Society, December 2014, American Chemical Society (ACS)

    Professor Mark O. Huising

  7. CRFR1 activation protects against cytokine-induced β-cell death

    Article • Journal of Molecular Endocrinology, October 2014, Bioscientifica

    Professor Mark O. Huising

  8. Corticotropin-releasing factor-binding protein (CRF-BP) inhibits CRF- and urotensin-I-mediated activation of CRF receptor-1 and -2 in common carp

    Article • General and Comparative Endocrinology, June 2014, Elsevier

    Professor Mark O. Huising

  9. TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling

    Article • Cell, May 2014, Elsevier

    Professor Mark O. Huising

  10. Maturation of Stem Cell-Derived Beta-cells Guided by the Expression of Urocortin 3

    Article • The Review of Diabetic Studies, January 2014, Society for Biomedical Diabetes Research (SBDR)

    Professor Mark O. Huising

  11. The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    Professor Mark O. Huising

  12. Control of Voltage-gated Potassium Channel Kv2.2 Expression by Pyruvate-Isocitrate Cycling Regulates Glucose-stimulated Insulin Secretion

    Article • Journal of Biological Chemistry, June 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Mark O. Huising

  13. Urocortin 3 Marks Mature Human Primary and Embryonic Stem Cell-Derived Pancreatic Alpha and Beta Cells

    Article • PLoS ONE, December 2012, PLOS

    Professor Mark O. Huising

  14. Recombinant human leptin attenuates stress axis activity in common carp (Cyprinus carpio L.)

    Article • General and Comparative Endocrinology, August 2012, Elsevier

    Professor Mark O. Huising

  15. STAT genes display differential evolutionary rates that correlate with their roles in the endocrine and immune system

    Article • February 2011

    Professor Mark O. Huising

  16. Glucocorticoids Differentially Regulate the Expression of CRFR1 and CRFR2α in MIN6 Insulinoma Cells and Rodent Islets

    Article • Endocrinology, January 2011, Endocrine Society

    Professor Mark O. Huising

  17. CRFR1 is expressed on pancreatic β cells, promotes β cell proliferation, and potentiates insulin secretion in a glucose-dependent manner

    Article • Proceedings of the National Academy of Sciences, December 2009, Proceedings of the National Academy of Sciences

    Professor Mark O. Huising

  18. Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution

    Article • March 2009, Bioscientifica

    Professor Mark O. Huising

  19. Residues of Corticotropin Releasing Factor-binding Protein (CRF-BP) That Selectively Abrogate Binding to CRF but Not to Urocortin 1

    Article • Journal of Biological Chemistry, January 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Mark O. Huising

  20. Corticotropin-releasing factor (CRF) and CRF-binding protein expression in and release from the head kidney of common carp: evolutionary conservation of the adrenal CRF system

    Article • June 2007, Bioscientifica

    Professor Mark O. Huising

  21. Real-time gene expression analysis in carp (Cyprinus carpio L.) skin: Inflammatory responses to injury mimicking infection with ectoparasites

    Article • Developmental & Comparative Immunology, January 2007, Elsevier

    Professor Mark O. Huising

  22. The first appearance of Rodlet cells in carp (Cyprinus carpio L.) ontogeny and their possible roles during stress and parasite infection

    Article • Fish & Shellfish Immunology, January 2007, Elsevier

    Professor Mark O. Huising

  23. Increased Leptin Expression in Common Carp (Cyprinus carpio) after Food Intake But Not after Fasting or Feeding to Satiation

    Article • Endocrinology, December 2006, Endocrine Society

    Professor Mark O. Huising

  24. Central and peripheral interleukin-1  and interleukin-1 receptor I expression and their role in the acute stress response of common carp, Cyprinus carpio L.

    Article • October 2006, Bioscientifica

    Professor Mark O. Huising

  25. Endurance exercise differentially stimulates heart and axial muscle development in zebrafish (Danio rerio)

    Article • AJP Regulatory Integrative and Comparative Physiology, May 2006, American Physiological Society

    Professor Mark O. Huising

  26. The presence of multiple and differentially regulated interleukin-12p40 genes in bony fishes signifies an expansion of the vertebrate heterodimeric cytokine family

    Article • Molecular Immunology, April 2006, Elsevier

    Professor Mark O. Huising

  27. Phylogeny and evolution of class-I helical cytokines

    Article • Journal of Endocrinology, April 2006, Bioscientifica

    Professor Mark O. Huising

  28. CRF and stress in fish

    Article • General and Comparative Endocrinology, March 2006, Elsevier

    Dr Peter H.M. Klaren, Professor Mark O. Huising

  29. Corticotropin-releasing hormone-receptor 1 (CRH-R1) and CRH-binding protein (CRH-BP) are expressed in the gills and skin of common carp Cyprinus carpio L. and respond to acute stress and infection

    Article • Journal of Experimental Biology, February 2006, The Company of Biologists

    Professor Mark O. Huising

  30. Peptides and proteins regulating food intake: a comparative view

    Article • Animal Biology, January 2006, Brill

    Professor Mark O. Huising

  31. Multiple and highly divergent IL-11 genes in teleost fish

    Article • Immunogenetics, July 2005, Springer Science + Business Media

    Professor Mark O. Huising

  32. The Remarkable Conservation of Corticotropin-Releasing Hormone (CRH)-Binding Protein in the Honeybee (Apis mellifera) Dates the CRH System to a Common Ancestor of Insects and Vertebrates

    Article • Endocrinology, May 2005, Endocrine Society

    Professor Mark O. Huising

  33. Regulation of the Stress Response in Early Vertebrates

    Article • Annals of the New York Academy of Sciences, April 2005, Wiley

    Professor Mark O. Huising

  34. Rag expression identifies B and T cell lymphopoietic tissues during the development of common carp (Cyprinus carpio)

    Article • Developmental & Comparative Immunology, January 2005, Elsevier

    Professor Mark O. Huising, Dr. Nuria Álvarez-Sánchez

  35. Overproduction of corticotropin-releasing hormone blocks germinal center formation: role of corticosterone and impaired follicular dendritic cell networks

    Article • Journal of Neuroimmunology, November 2004, Elsevier

    Professor Mark O. Huising

  36. Three novel carp CXC chemokines are expressed early in ontogeny and at nonimmune sites

    Article • European Journal of Biochemistry, September 2004, Wiley

    Professor Mark O. Huising

  37. Localization, expression and control of adrenocorticotropic hormone in the nucleus preopticus and pituitary gland of common carp (Cyprinus carpio L.)

    Article • July 2004, Bioscientifica

    Professor Mark O. Huising

  38. Structural characterisation of a cyprinid (Cyprinus carpio L.) CRH, CRH-BP and CRH-R1, and the role of these proteins in the acute stress response

    Article • June 2004, Bioscientifica

    Professor Mark O. Huising

  39. The molecular evolution of the interleukin-1 family of cytokines; IL-18 in teleost fish

    Article • Developmental & Comparative Immunology, May 2004, Elsevier

    Professor Mark O. Huising

  40. CXC chemokines and leukocyte chemotaxis in common carp (Cyprinus carpio L.)

    Article • Developmental & Comparative Immunology, December 2003, Elsevier

    Professor Mark O. Huising

  41. Increased efficacy of immersion vaccination in fish with hyperosmotic pretreatment

    Article • Vaccine, October 2003, Elsevier

    Professor Mark O. Huising

  42. Response to Shields: Molecular evolution of CXC chemokines and receptors

    Article • Trends in Immunology, July 2003, Elsevier

    Professor Mark O. Huising

  43. Molecular evolution of CXC chemokines: extant CXC chemokines originate from the CNS

    Article • Trends in Immunology, June 2003, Elsevier

    Professor Mark O. Huising

  44. Neuroendocrine–immune interactions in fish: a role for interleukin-1

    Article • Veterinary Immunology and Immunopathology, September 2002, Elsevier

    Professor Mark O. Huising