All Stories

  1. Population pharmacokinetic model of lithium and drug compliance assessment
  2. Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion
  3. Assessment of the Regulatory Methods for the Comparison of Highly Variable Dissolution Profiles
  4. Enhancing Oral Absorption of β-Lapachone: Progress Till Date
  5. Importance and applications of cell- and tissue-based in vitro models for drug permeability screening in early stages of drug development
  6. Exploring different strategies for imbalanced ADME data problem: case study on Caco-2 permeability modeling
  7. Drug gastrointestinal absorption in rat: Strain and gender differences
  8. In Situ Perfusion Model in Rat Colon for Drug Absorption Studies: Comparison with Small Intestine and Caco-2 Cell Model
  9. Permeability Study of Polyphenols Derived from a Phenolic-Enriched Hibiscus sabdariffa Extract by UHPLC-ESI-UHR-Qq-TOF-MS
  10. In vitro–in vivocorrelations: general concepts, methodologies and regulatory applications
  11. Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid
  12. In vitro methods for assessing drug access to the brain
  13. Blood–brain barrier and drug delivery
  14. Validation of a semi-physiological model for caffeine in healthy subjects and cirrhotic patients
  15. Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors
  16. Purely in Silico BCS Classification: Science Based Quality Standards for the World’s Drugs
  17. Innovative in Vitro Method To Predict Rate and Extent of Drug Delivery to the Brain across the Blood–Brain Barrier
  18. Semisynthesis, Cytotoxic Activity, and Oral Availability of New Lipophilic 9-Substituted Camptothecin Derivatives
  19. Provisional Classification andin SilicoStudy of Biopharmaceutical System Based on Caco-2 Cell Permeability and Dose Number
  20. The Use of Rule-Based and QSPR Approaches in ADME Profiling: A Case Study on Caco-2 Permeability
  21. Hydrogels: an interesting strategy for smart drug delivery
  22. In vitro–in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate
  23. In vivo Methods for Oral Bioavailability Studies
  24. In Silico Prediction of Caco-2 Cell Permeability by a Classification QSAR Approach
  25. A new mathematical approach for the estimation of the AUC and its variability under different experimental designs in preclinical studies
  26. Computer simulations for bioequivalence trials: Selection of analyte in BCS drugs with first-pass metabolism and two metabolic pathways
  27. Unique pharmacology of KAR-2, a potential anti-cancer agent: Absorption modelling and selective mitotic spindle targeting
  28. Computer simulations of bioequivalence trials: Selection of design and analyte in BCS drugs with first-pass hepatic metabolism: Part II. Non-linear kinetics
  29. Computer simulations of bioequivalence trials: Selection of design and analyte in BCS drugs with first-pass hepatic metabolism: Linear kinetics (I)
  30. How and Where Are Drugs Absorbed?
  31. In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation within vitro results
  32. A Provisional Biopharmaceutical Classification of the Top 200 Oral Drug Products in the United States, Great Britain, Spain, and Japan
  33. A topological substructural approach for the prediction of P-glycoprotein substrates
  34. Computational method to predict human intestinal absorption
  35. In silico prediction of central nervous system activity of compounds. Identification of potential pharmacophores by the TOPS–MODE approach
  36. TOPS‐MODE Approach for the Prediction of Blood–Brain Barrier Permeation
  37. PAMPA—a drug absorption in vitro model
  38. A novel approach to determining physicochemical and absorption properties of 6-fluoroquinolone derivatives: experimental assessment
  39. Pharmacokinetics, bioavailability and absorption of flumequine in the rat
  40. Validation of a biophysical drug absorption model by the PATQSAR system
  41. Correlation BetweenIn Vitro,In Situ, andIn Vivo Models