All Stories

  1. Immunohistochemical Analysis of Androgen Receptor Expression Predicts the Prognosis of Metastatic Castration‐Sensitive Prostate Cancer Patients Receiving Abiraterone Acetate
  2. Comparative analysis of gut microbiota in hormone‐sensitive and castration‐resistant prostate cancer in Japanese men
  3. A machine learning-based method for feature reduction of methylation data for the classification of cancer tissue origin
  4. Exploring the relationship between ulcerative colitis, colorectal cancer, and prostate cancer
  5. A cross‐species analysis of fecal microbiomes in humans and mice reveals similarities and dissimilarities associated with prostate cancer risk
  6. Downregulated expression of PBRM1 in sarcomatoid hepatocellular carcinoma
  7. Moving toward improved immune checkpoint immunotherapy for advanced prostate cancer
  8. Abstract 6330: Countering antidrug antibodies to programmed cell death-1 blockade in mouse Pten-null prostate cancer
  9. Abstract 640: Exploring the relationships between prostate cancer, colorectal cancer, and ulcerative colitis
  10. Abstract 1838: Immunomodulatory effects of curcumin monoglucuronide on PD1 immune checkpoint blockade in mouse Pten-null prostate cancer
  11. Abstract 3044: Integrative gut microbiome analysis of human and mouse prostate cancer
  12. Abstract 2877: Profiling of myeloid-derived suppressor cells in Pten-deficient in prostate cancer progression
  13. Abstract 5155: Targeting tumor infiltrating myeloid cells in prostate cancer
  14. The Gut-Prostate Axis: A New Perspective of Prostate Cancer Biology through the Gut Microbiome
  15. Emerging Relationship between the Gut Microbiome and Prostate Cancer
  16. Performance of Idylla™ RAS-BRAF mutation test for formalin-fixed paraffin-embedded tissues of colorectal cancer
  17. Gut microbiome and prostate cancer
  18. Connecting the Dots Between the Gut–IGF-1–Prostate Axis: A Role of IGF-1 in Prostate Carcinogenesis
  19. Patients with polyclonal hepatocellular carcinoma are at a high risk of early recurrence and have a poor recurrence-free survival period
  20. Intestinal Microbiota and Gene Expression Reveal Similarity and Dissimilarity Between Immune-Mediated Colitis and Ulcerative Colitis
  21. Disseminated intravascular coagulation induced by pazopanib following combination therapy of nivolumab plus ipilimumab in a patient with metastatic renal cell carcinoma
  22. Context-Specific Efficacy of Apalutamide Therapy in Preclinical Models of Pten-Deficient Prostate Cancer
  23. Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy‐induced colitis
  24. Transcriptome Profiling and Metagenomic Analysis Help to Elucidate Interactions in an Inflammation-Associated Cancer Mouse Model
  25. Higher neutrophil-to-lymphocyte ratio after the first cycle of the first-line chemotherapy is associated with poor cancer specific survival of upper urinary tract carcinoma patients
  26. Mucosal microbiota and gene expression are associated with long-term remission after discontinuation of adalimumab in ulcerative colitis
  27. Abstract 3416: Androgen deprivation following JAK1/2 and PD-L1 inhibition improves antitumor efficacy in mouse models of Pten-deficient prostate cancer
  28. Abstract 4468: Cross-species analysis and immunophenotyping using of a focused panel of immune-responsive genes
  29. Abstract 3340: Prostate cancer alters gut microbiota in mice
  30. Abstract 3341: Systemic targeted JAK1/2 therapy for mouse Pten-deficient prostate cancer model influences the diversity and composition of the gut microbiome
  31. Abstract 1071: Targeting A2aR in mouse Pten-deficient prostate cancer
  32. Abstract 5610: The multi tyrosine kinase inhibitor TAS-115 promotes innate and adaptive immune responses of androgen deprivation therapy in mouse prostate cancer
  33. Chemopreventive effects of nanoparticle curcumin in a mouse model of Pten-deficient prostate cancer
  34. Targeting castration-resistant prostate cancer with androgen receptor antisense oligonucleotide therapy
  35. Abstract 4996: A real-time PCR-based approach to quantitatively assess tumor immune profiles and immune responses
  36. Abstract 3951: Apalutamide reworks the immune composition of prostate tumors
  37. Abstract 1613: Dietary isoflavone decreases prostate cancer progression and improves survival in conditional Pten/Trp53-deficient mice
  38. Abstract 5023: Immunomodulation of the multi-tyrosine kinase inhibitor TAS-115 in a mouse model of prostate cancer
  39. HOXA10 expression profiling in prostate cancer
  40. Generation of PTEN‑knockout (‑/‑) murine prostate cancer cells using the CRISPR/Cas9 system and comprehensive gene expression profiling
  41. Abstract 3737: Apalutamide (ARN-509) demonstrates therapeutic efficacy in genetically engineered mouse models of Pten-deficient prostate cancer
  42. Abstract 947: Influence of abiraterone therapy on anti-tumor immunity in genetically engineered mouse prostate cancer models
  43. Abstract 5169: Novel target molecules for treatment of cancer of unknown primary
  44. Abstract 2868: Preclinical evaluation of the multi tyrosine kinase inhibitor TAS-115 in genetically engineered mouse models of prostate cancer
  45. Abstract 4825: Targeting PIM and AKT kinases impairs tumor growth and improves overall survival in a murine model of advanced castration-resistant prostate cancer
  46. Abstract 1715: Treatment-dependent effects of androgen receptor signaling suppression on immune modulation in mouse Pten-deficient prostate cancer
  47. Prostate cancer immunotherapy
  48. Clonal composition of human ovarian cancer based on copy number analysis reveals a reciprocal relation with oncogenic mutation status
  49. SCF-KIT signaling induces endothelin-3 synthesis and secretion: Thereby activates and regulates endothelin-B-receptor for generating temporally- and spatially-precise nitric oxide to modulate SCF- and or KIT-expressing cell functions
  50. Abstract 751: Characterization of STAT3 activation in human prostate cancer
  51. Abstract 1096: Co-targeting of AKT and Pim kinases in mouse PTEN-deficient prostate cancer
  52. Abstract 3684: Inhibition of STAT3 by antisense oligonucleotide treatment decreases the immune suppressive tumor microenvironment in syngeneic and GEM tumor models
  53. Abstract 4702: PD-L1 blockade in preclinical models of PTEN-deficient prostate cancer
  54. Abstract 1582: Therapeutic potential of combination therapy using a next generation antisense oligonucleotide targeting the androgen receptor and AKT inhibition with AZD5363 in genetically engineered mouse models of prostate cancer
  55. Efficacy of irreversible EGFR-TKIs for the uncommon secondary resistant EGFR mutations L747S, D761Y, and T854A
  56. Clinical significance of Akt2 in advanced pancreatic cancer treated with erlotinib
  57. Hypoxia-inducing factor (HIF)-1α-derived peptide capable of inducing cancer-reactive cytotoxic T lymphocytes from HLA-A24+ patients with renal cell carcinoma
  58. FGFR gene alterations in lung squamous cell carcinoma are potential targets for the multikinase inhibitor nintedanib
  59. MEK inhibitors against MET-amplified non-small cell lung cancer
  60. Afatinib against Esophageal or Head-and-Neck Squamous Cell Carcinoma: Significance of Activating Oncogenic HER4 Mutations in HNSCC
  61. Abstract 2014: Alternative splicing is a frequent event in mouse PTEN-deficient prostate cancer
  62. Abstract 954: Analysis of noncoding RNA expression in a mouse model of PTEN-deficient prostate cancer
  63. Abstract 4315: Effects of increased dietary fat consumption on prostate cancer progression in genetically engineered mice
  64. Abstract 3538: Effects of oral chloroquine administration on a preclinical mouse model of PTEN/p53-deficient prostate cancer
  65. Abstract 3864: The Jak1/2 inhibitor AZD1480 suppresses tumor growth and metastasis in genetically engineered mouse models of PTEN-deficient prostate cancer
  66. Sensitivities to various epidermal growth factor receptor‐tyrosine kinase inhibitors of uncommon epidermal growth factor receptor mutations L861Q and S768I: What is the optimal epidermal growth factor receptor‐tyrosine ki...
  67. Functional Analyses of Mutations in Receptor Tyrosine Kinase Genes in Non–Small Cell Lung Cancer: Double-Edged Sword of DDR2
  68. Increased FGF19 copy number is frequently detected in hepatocellular carcinoma with a complete response after sorafenib treatment
  69. Significance of FGF9 gene in resistance to anti-EGFR therapies targeting colorectal cancer: A subset of colorectal cancer patients withFGF9upregulation may be resistant to anti-EGFR therapies
  70. Efficacy of targeted AKT inhibition in genetically engineered mouse models of PTEN -deficient prostate cancer
  71. An activating ALK gene mutation in ALK IHC-positive/FISH-negative non-small cell lung cancer
  72. Clinicopathological and genetic differences between low-grade and high-grade colorectal mucinous adenocarcinomas
  73. 2169 Clinicopathological and genetic differences between low-grade and high-grade colorectal mucinous adenocarcinoma
  74. 259 Fibroblast growth factor 9 gene amplification can induce resistance to anti-EGFR therapy in colorectal cancer
  75. Identification of Programmed Death Ligand 1–derived Peptides Capable of Inducing Cancer-reactive Cytotoxic T Lymphocytes From HLA-A24+ Patients With Renal Cell Carcinoma
  76. An activating ALK gene mutation in ALK IHC-positive/FISH-negative nonsmall-cell lung cancer
  77. Abstract 1845: Chloroquine demonstrates limited effectiveness in an autochthonous preclinical model of prostate cancer
  78. Abstract 1857: Effects of long-term chloroquine chemotherapy in a preclinical model of PTEN-deficient prostate cancer
  79. Abstract 1850: Evaluation of Pim-1 kinase inhibition in a preclinical model of mouse prostate cancer
  80. Abstract 5456: FGF9 gene amplification can induce resistance to anti-EGFR therapy in colorectal cancer
  81. Abstract 4212: Inhibition of mouse PTEN-deficient prostate cancer with next generation antisense oligonucleotide targeting the androgen receptor
  82. Abstract 4958: Melanoma transition is frequently accompanied by a loss of cytoglobin, a putative tumor suppressor, in melanocytes
  83. Abstract 4699: Preclinical activity of the AKT inhibitor AZD5363 in PTEN-deficient mouse models of prostate cancer
  84. Abstract 1856: Preclinical effects of dual AKT/MAPK inhibition in PTEN-deficient prostate cancer
  85. EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition
  86. Evaluation of in vivo responses of sorafenib therapy in a preclinical mouse model of PTEN-deficient of prostate cancer
  87. Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing
  88. New polycomb group protein enhancer of zeste homolog (EZH) 2-derived peptide with the potential to induce cancer-reactive cytotoxic T lymphocytes in prostate cancer patients with HLA-A3 supertype alleles
  89. Chronic nicotine exposure mediates resistance to EGFR-TKI in EGFR -mutated lung cancer via an EGFR signal
  90. Conditional PTEN-deficient Mice as a Prostate Cancer Chemoprevention Model
  91. Performance of a novel KRAS mutation assay for formalin-fixed paraffin embedded tissues of colorectal cancer
  92. Activin signal promotes cancer progression and is involved in cachexia in a subset of pancreatic cancer
  93. Inhibition of β-Catenin Enhances the Anticancer Effect of Irreversible EGFR-TKI in EGFR-Mutated Non–small-cell Lung Cancer with a T790M Mutation
  94. Activated MET acts as a salvage signal after treatment with alectinib, a selective ALK inhibitor, in ALK-positive non-small cell lung cancer
  95. MEK Inhibitor for Gastric Cancer with MEK1 Gene Mutations
  96. Abstract 611: Co-targeting the PI3K and androgen receptor signal pathways in castration resistant prostate cancer
  97. Abstract 613: Combining PI3K and 5alpha-reductase inhibitors improves the treatment response in a mouse model of PTEN-deficient prostate cancer
  98. Abstract 1201: Establishment and characterization of cell lines derived from a murine model of PTEN-deficient prostate cancer
  99. Abstract 4729: Expression of lumican is negatively associated with the risk of biochemical recurrence in human prostate cancer
  100. Abstract 84: Functional evaluation of synchronous inactivation of PTEN and P53 in a murine model of prostate cancer
  101. Abstract 3912: The role of autophagy in prostate tumorigenesis and its therapeutic implications
  102. Synergistic antitumor effects of S-1 with eribulin in vitro and in vivo for triple-negative breast cancer cell lines
  103. Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition
  104. KIAA1199 interacts with glycogen phosphorylase kinase β-subunit (PHKB) to promote glycogen breakdown and cancer cell survival
  105. Androgen deprivation induces phenotypic plasticity and promotes resistance to molecular targeted therapy in aPTEN-deficient mouse model of prostate cancer
  106. Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer
  107. Identification of erythropoietin receptor-derived peptides having the potential to induce cancer-reactive cytotoxic T lymphocytes from HLA-A24+ patients with renal cell carcinoma
  108. Melanoma Transition Is Frequently Accompanied by a Loss of Cytoglobin Expression in Melanocytes: A Novel Expression Site of Cytoglobin
  109. Osteopontin knockdown in the kidneys of hyperoxaluric rats leads to reduction in renal calcium oxalate crystal deposition
  110. Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production
  111. The OCT4 pseudogene POU5F1B is amplified and promotes an aggressive phenotype in gastric cancer
  112. Construction of a 3D Culture Assay System for Anti-Cancer Drug Testing
  113. Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer
  114. Abstract 4608: Autophagy is required for prostate cancer progression.
  115. Abstract 3688: Leptin contributes to prostate cancer progression.
  116. Slug increases sensitivity to tubulin‐binding agents via the downregulation of βIII and βIVa‐tubulin in lung cancer cells
  117. Effects of the Rho kinase inhibitor, hydroxyfasudil, on bladder dysfunction and inflammation in rats with HCl‐induced cystitis
  118. Overexpression of FOXQ1 is Important Factor in Tumorigenecity and Tumor Growth
  119. Abstract 539: A preclinical model to evaluate the risk of increased dietary fat consumption and prostate cancer progression
  120. Abstract 424: Amplification of OCT4-pseudogene POU5F1B is a poor prognostic factor in gastric cancer
  121. Abstract 2755: Enhanced anti-tumor effects using a combinatorial targeted treatment strategy in a preclinical model of prostate cancer
  122. Abstract 5178: Evaluation of lumican expression profiles in prostate cancer
  123. Abstract 3629: HOXA10 expression profiles in prostate cancer
  124. Abstract 3876: Role of Stat3 transcriptional activation in a preclinical mouse model of prostate cancer and potential as a therapeutic target
  125. Abstract 3517: Use of a novel synthetic biomaterial to induce mild whole body hyperthermia for the treatment of cancer in a preclinical model
  126. Preclinical Remodeling of Human Prostate Cancer through the PTEN/AKT Pathway
  127. Aza-derivatives of resveratrol are potent macrophage migration inhibitory factor inhibitors
  128. Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer
  129. A new molecular targeted therapeutic approach for renal cell carcinoma with a p16 functional peptide using a novel transporter system
  130. 1769 A PHASE I TRIAL OF VEGFR1 PEPTIDE VACCINES FOR PATIENTS WITH METASTATIC RENAL CELL CARCINOMA
  131. Abstract 433: Altered expression of lumican in prostate cancer is identified by microarray analysis
  132. Abstract 806: Anti-tumor effects of low temperature whole body hyperthermia on human bladder cancer cells in vivo
  133. Abstract 2167: Identification of aberrant expression of HOXA10 in prostate cancer
  134. Abstract 843: Increased consumption of dietary fat contributes to increased prostate cancer-specific mortality in a transgenic mouse model of prostate cancer
  135. Intravesical Bacillus Calmette-Guerin Therapy for Grade 3 Non-Muscle Invasive Bladder Cancer: Results of Six or Eight Successive Instillations
  136. Abstract 1095: Short Poly A sequence in HGF promoter region is involved in overexpression of HGF in cancer cells
  137. Abstract 3579: Sorafenib inhibits tumor development and growth in a transgenic mouse model of prostate cancer
  138. Antitumor Activity of BIBF 1120, a Triple Angiokinase Inhibitor, and Use of VEGFR2+pTyr+ Peripheral Blood Leukocytes as a Pharmacodynamic Biomarker In Vivo
  139. Carvedilol protects tubular epithelial cells from ischemia–reperfusion injury by inhibiting oxidative stress
  140. Abstract 3893: Overexpression of FOXQ1 is important factor in tumorigenicity and tumor growth
  141. Abstract 956: Targeting prostate cancer chemoprevention via the androgen receptor in a preclinical mouse model
  142. Immunological evaluation of personalized peptide vaccination monotherapy in patients with castration-resistant prostate cancer
  143. FOXQ1 Is Overexpressed in Colorectal Cancer and Enhances Tumorigenicity and Tumor Growth
  144. Role of syndecan-1 (CD138) in cell survival of human urothelial carcinoma
  145. Syndecan-1, a new target molecule involved in progression of androgen-independent prostate cancer
  146. A Novel Human AlkB Homologue, ALKBH8, Contributes to Human Bladder Cancer Progression
  147. l-Arginine Decreases Fluid-Percussion Injury-Induced Neuronal Nitrotyrosine Immunoreactivity in Rats
  148. Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation
  149. Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases
  150. A NOVEL p16 PEPTIDE THERAPY RADIOSENSITIZES PROSTATE CANCER
  151. FUNCTIONAL PEPTIDE THERAPY WITH PTEN IN PROSTATE CANCER
  152. Tumor vaccines in renal cell carcinoma
  153. 882: Intravesical Instillation of Liposomal Doxorubicin Nanoparticles in Mouse Superficial Bladder Cancer
  154. 650: The Role of PTEN in Hormone Independent Prostate Cancer Derived by Prostate Specific Deletion of PTEN
  155. Expression of Cellular Adhesion Proteins and Abnormal Glycoproteins in Human Aberrant Crypt Foci
  156. Protective effects of zinc chelation in traumatic brain injury correlate with upregulation of neuroprotective genes in rat brain
  157. Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen
  158. Allium vegetables: their role in the prevention of cancer
  159. Inhibition of aberrant crypt growth by non‐steroidal anti‐inflammatory agents and differentiation agents in the rat colon
  160. Micronuclei, a biomarker for chemoprevention trials: Results of a randomized study in oral pre‐malignancy
  161. GFP image analysis in the mouse orthotopic bladder cancer model
  162. Micronuclei in bronchial biopsy specimens from heavy smokers: Characterization of an intermediate marker of lung carcinogenesis