All Stories

  1. Sophocarpine Inhibits Proliferation and Triggers Apoptosis in Breast Cancer Cells by Modulating the miR-21/PTEN/AKT and ERK1/2 Signaling Networks

    Article • Pharmaceuticals, September 2026, MDPI AG

    Prof Mahmoud Essmat Balbaa

  2. Thymoquinone-conjugated liposomes improve cytotoxic and proapoptotic effects against hepatocellular cancer by altering the EGFR/ERK/MEK signaling axis

    Article • Discover Oncology, October 2025, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  3. Biochemical and molecular evaluation of resveratrol and selenium nanoparticles in managing type 2 diabetes and its complications

    Article • Scientific Reports, July 2025, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  4. Multi-Target Glitazones for Modulating Peroxisome Proliferator-Activated Receptor-γ, Cyclooxygenase-2, and Carbonic Anhydrases for the Management of Metabolic Dysfunction

    Article • ACS Pharmacology & Translational Science, May 2025, American Chemical Society (ACS)

    Prof Mahmoud Essmat Balbaa

  5. Bee venom-loaded EGFR-targeting peptide-coupled chitosan nanoparticles for effective therapy of hepatocellular carcinoma by inhibiting EGFR-mediated MEK/ERK pathway

    Article • PLOS One, August 2022, PLOS

    Prof Mahmoud Essmat Balbaa

  6. New 4-(arylidene)amino-1,2,4-traizole-5-thiol derivatives and their acyclo thioglycosides as α-glucosidase and α-amylase inhibitors: Design, synthesis, and molecular modelling studies

    Article • Journal of Molecular Structure, July 2022, Elsevier

    Prof Mahmoud Essmat Balbaa

  7. The hepatotoxicity of Nigella sativa oil linked to the route of Administration

    Article • The Natural Products Journal, May 2022, Bentham Science Publishers

    Prof Mahmoud Essmat Balbaa, Marwa El-Zeftawy

  8. Curcumin Zn oxide Nanoparticles

    Article • Pharmaceutics, November 2021, MDPI AG

    Prof Mahmoud Essmat Balbaa

  9. Therapeutic Screening of Herbal Remedies for the Management of Diabetes

    Article • Molecules, November 2021, MDPI AG

    Prof Mahmoud Essmat Balbaa

  10. Ameliorative effect of curcumin and zinc oxide nanoparticles on multiple mechanisms in obese rats with induced type 2 diabetes

    Article • Scientific Reports, October 2021, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  11. polyaromatic hydrocarbons

    Article • Ocean and Coastal Research, January 2021, FapUNIFESP (SciELO)

    Prof Mahmoud Essmat Balbaa

  12. Erectile dysfunction drugs altered the activities of antioxidant enzymes, oxidative stress and the protein expressions of some cytochrome P450 isozymes involved in the steroidogenesis of steroid hormones

    Article • PLOS One, November 2020, PLOS

    Prof Salah Sheweita, Prof Mahmoud Essmat Balbaa

  13. Cell Signaling in Hepatocellular Carcinoma

    Article • American Research Journal of Biosciences, November 2020, American Research Journals

    Prof Mahmoud Essmat Balbaa

  14. Synergistic effect of nano-selenium and metformin on type 2 diabetic rat model: Diabetic complications alleviation through insulin sensitivity, oxidative mediators and inflammatory markers

    Article • PLOS One, August 2019, PLOS

    Prof Mahmoud Essmat Balbaa

  15. Action of Thioglycosides on the Oxidative Stress and Glycosidases.

    Article • Letters in Drug Design & Discovery, May 2019, Bentham Science Publishers

    Dr Doaa Osman Awad, Professor Doctor Nadjet REZKI, El Sayed H. El Ashry, Professor Mohamed E. I. Badawy, Prof Mahmoud Essmat Balbaa, Ahmed AbdElaal , Omayma Sadek, Shimaa Mahsoub

  16. Professor of biochemistry. The duties include teaching and research activities.

    Article • Environmental Toxicology, June 2018, Wiley

    yasmin shahin, Prof Mahmoud Essmat Balbaa

  17. Antioxidants and radical scavenging role of Leek (Allium kurrat) against aflatoxin-contaminated peanut

    Article • Toxin Reviews, November 2017, Taylor & Francis

    Prof Mahmoud Essmat Balbaa

  18. N-nitrosamines induced infertility and hepatotoxicity in male rabbits

    Article • Environmental Toxicology, June 2017, Wiley

    Prof Salah Sheweita, Prof Mahmoud Essmat Balbaa

  19. Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs

    Article • PLOS One, May 2017, PLOS

    Prof Mahmoud Essmat Balbaa

  20. Zinc and curcumin lower arylsulfatses and some metabolic parameters in streptozotocin-induced diabetes

    Article • Journal of Diabetes & Metabolic Disorders, March 2017, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  21. Association between angiotensin-converting enzyme insertion/deletion gene polymorphism and end-stage renal disease in lebanese patients with diabetic nephropathy

    Article • Saudi Journal of Kidney Diseases and Transplantation, January 2017, Medknow

    Jamilah Borjac, Prof Mahmoud Essmat Balbaa

  22. Management of Diabetes by the Natural Products

    Article • Biochemistry & Physiology Open Access, January 2017, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  23. Drug-Metabolizing Enzymes and Metabolic Diseases: Role of Antioxidants

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Prof Salah Sheweita, Prof Mahmoud Essmat Balbaa

  24. Nigella sativaRelieves the Altered Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats Fed with a High-Fat Diet

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Prof Mahmoud Essmat Balbaa

  25. Diabetes and Cell Signaling

    Article • Biochemistry & Physiology Open Access, January 2016, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  26. Protein Phosphorylation

    Article • Biochemistry & Physiology Open Access, January 2016, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  27. Effect of Natural Products on Some Glycosidases and Their Expected Hypoglycemic Potential

    Article • International Journal of Biochemistry Research & Review, January 2015, Sciencedomain International

    Prof Mahmoud Essmat Balbaa

  28. Aspartate Transcarbamylase

    Article • Biochemistry & Physiology Open Access, January 2015, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  29. Biological Effect of Glycosyl-Oxadiazolinethione and Glycosyl-sulfanyloxadiazole Derivatives through their in vitro Inhibition of Glycosidases from Bacteria and Normal or Diabetic Rats

    Article • Letters in Drug Design & Discovery, December 2014, Bentham Science Publishers

    Prof Mahmoud Essmat Balbaa

  30. Anti-diabetic activity of different oils through their effect on arylsulfatases

    Article • Journal of Diabetes & Metabolic Disorders, December 2014, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  31. Arylsufatases

    Article • Biochemistry & Physiology Open Access, January 2014, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  32. Inhibition of Glycosidases

    Article • Biochemistry & Physiology Open Access, January 2014, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  33. Epidermal growth factor, its receptor and transforming growth factor-β1 in the diagnosis of HCV-induced hepatocellular carcinoma

    Article • Medical Oncology, August 2013, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  34. Detection of New Point Mutations of BRCA1 and BRCA2 in Breast Cancer Patients

    Article • Biochemical Genetics, July 2013, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  35. Importance of Growth Factors

    Article • Biochemistry & Physiology Open Access, January 2013, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  36. Some heterocyclic thione derivatives exhibit anticoccidial activity by inhibiting glycosidases.

    Article • Acta Biochimica Polonica, October 2012, Polskie Towarzystwo Biochemiczne (Polish Biochemical Society)

    Prof Mahmoud Essmat Balbaa

  37. Enzyme Inhibitors as Therapeutic Tools

    Article • Biochemistry & Physiology Open Access, January 2012, OMICS Publishing Group

    Prof Mahmoud Essmat Balbaa

  38. Effect of calcium treatment on blood parameters, gonadal development and the structure of bone in immature female rats

    Article • Journal of Physiology and Biochemistry, December 2011, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  39. CYP1A1, CYP2E1, and GSTM1 Gene Polymorphisms and Susceptibility to Colorectal and Gastric Cancer Among Lebanese

    Article • Genetic Testing and Molecular Biomarkers, June 2011, Mary Ann Liebert Inc

    Prof Mahmoud Essmat Balbaa

  40. Inhibition of α-glucosidase and α-amylase by diaryl derivatives of imidazole-thione and 1,2,4-triazole-thiol

    Article • European Journal of Medicinal Chemistry, June 2011, Elsevier

    Prof Mahmoud Essmat Balbaa

  41. The clinical relevance of urine-based markers for diagnosis of bladder cancer

    Article • Medical Oncology, March 2011, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  42. Succinate cytochrome c reductase in schistosomiasis: in vitro inhibition by some schistosomicidal drugs

    Article • Journal of Physiology and Biochemistry, August 2010, Springer Science + Business Media

    Prof Mahmoud Essmat Balbaa

  43. Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2008, Taylor & Francis

    Prof Mahmoud Essmat Balbaa

  44. In vitroeffect of schistosomicidal drugs on hepatic arylsulfatase B from theSchistosoma-infected mouse

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2006, Taylor & Francis

    Prof Mahmoud Essmat Balbaa

  45. Effect of some Cardiac and Respiratory Drugs on Succinate-Cytochrome c Reductase

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, August 2004, Taylor & Francis

    Prof Mahmoud Essmat Balbaa

  46. Some hydrolases in human schistosomiasis with special reference to arylsulfatase B

    Article • International Journal of Environmental Studies, December 2003, Taylor & Francis

    Prof Mahmoud Essmat Balbaa

  47. INHIBITION OF SOME HEPATIC GLYCOSIDASES BY THE DISECO NUCLEOSIDE, 4-AMINO-3-(D-GLUCOPENTITOL-1-YL)- 5-MERCAPTO-1,2,4-TRIAZOLE AND ITS 3-METHYL ANALOG

    Article • Nucleosides Nucleotides & Nucleic Acids, December 2002, Taylor & Francis

    Prof Mahmoud Essmat Balbaa

  48. Inhibition of Succinate-cytochrome C Reductase by a Ferromacrocyclic Complex

    Article • Journal of Enzyme Inhibition, January 2001, Taylor & Francis

    Prof Mahmoud Essmat Balbaa

  49. Inhibition of some hepatic lysosomal glycosidases by ethanolamines and phenyl 6-deoxy-6-(morpholin-4-yl)-β-d-glucopyranoside

    Article • Carbohydrate Research, April 1999, Elsevier

    Prof Mahmoud Essmat Balbaa

  50. Enhancement of Lysosomal Enzymes by the Pyrethroids, Fenvalerate and trans-Cypermethrin.

    Article • Eisei kagaku, January 1998, Pharmaceutical Society of Japan

    Prof Mahmoud Essmat Balbaa

  51. Regulation of glycolipid sulfotransferase by tyrosine kinases in human renal cancer cells

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, January 1996, Elsevier

    Prof Mahmoud Essmat Balbaa

  52. Mechanism of pepsin-catalyzed aminotranspeptidation reactions

    Article • International Journal of Biochemistry, January 1994, Elsevier

    Prof Mahmoud Essmat Balbaa

  53. Secondary Substrate Binding in Aspartic Proteinases: Contributions of Subsites S3 and S′2 to kcat

    Article • Archives of Biochemistry and Biophysics, November 1993, Elsevier

    Prof Mahmoud Essmat Balbaa

  54. Alterations of protein kinase isozymes in transplantable human lung cancer with special reference to the phosphorylation of arylsulfatase B

    Article • Lung Cancer, January 1989, Elsevier

    Prof Mahmoud Essmat Balbaa

  55. Alterations of protein kinase isozymes in transplantable human lung cancer with special reference to the phosphorylation of arylsulfatase B

    Article • Biochemical and Biophysical Research Communications, January 1988, Elsevier

    Prof Mahmoud Essmat Balbaa

  56. Phosphorylation of human lysosomal arylsulfatase B by cAMP-dependent protein kinase. Different sites of phosphorylation between normal and cancer tissues.

    Article • Journal of Biological Chemistry, January 1987, Elsevier

    Prof Mahmoud Essmat Balbaa

  57. The Use of Liposomes in Enzymes and Drug Design

    Article • IGI Global

    Prof Mahmoud Essmat Balbaa