All Stories

  1. Optimizing multifunctional fluorescent ligands for intracellular labeling
  2. 3D imaging of Sox2 enhancer clusters in embryonic stem cells
  3. Evolved differences in larval social behavior mediated by novel pheromones
  4. Integrated action of pheromone signals in promoting courtship behavior in male mice
  5. Bright Building Blocks for Chemical Biology
  6. Single-molecule tracking of the transcription cycle by sub-second RNA detection
  7. Decoupled Roles for the Atypical, Bifurcated Binding Pocket of the ybfF Hydrolase
  8. Rhodium(III)-Catalyzed Indazole Synthesis by C–H Bond Functionalization and Cyclative Capture
  9. Carbofluoresceins and Carborhodamines as Scaffolds for High-Contrast Fluorogenic Probes
  10. The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima
  11. Excitation Spectra and Brightness Optimization of Two-Photon Excited Probes
  12. Advances in the chemistry of small molecule fluorescent probes
  13. Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
  14. Facile and General Synthesis of Photoactivatable Xanthene Dyes
  15. Cellular Uptake of Ribonuclease A Relies on Anionic Glycans
  16. Onconase cytotoxicity relies on the distribution of its positive charge
  17. Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells
  18. A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells
  19. Ester Bonds in Prodrugs
  20. Bright Ideas for Chemical Biology
  21. Trimethyl Lock: A Stable Chromogenic Substrate for Esterases
  22. Intraspecies Regulation of Ribonucleolytic Activity
  23. Cytotoxic Ribonucleases:  The Dichotomy of Coulombic Forces
  24. Tuning the p K a of Fluorescein to Optimize Binding Assays
  25. Latent Blue and Red Fluorophores Based on the Trimethyl Lock
  26. Fluorogenic Label for Biomolecular Imaging