All Stories

  1. Sulfonamide a Valid Scaffold for Antioxidant Drug Development
  2. Synthesized 2-Trifluoromethylquinazolines and Quinazolinones Protect BV2 and N2a Cells against LPS- and H2O2-induced Cytotoxicity
  3. Targeting Host Cell Proteases to Prevent SARS-CoV-2 Invasion
  4. New trends in the pharmacological intervention of PPARs in obesity: Role of natural and synthetic compounds_
  5. Influence of Oxidative Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate Dehydrogenase
  6. The Effects of Trifluoromethylated Derivatives on Prostaglandin E2 and Thromboxane A2 Production in Human Leukemic U937 Macrophages
  7. Post-translational modifications of proteins in antiphospholipid antibody syndrome
  8. Modulation of Oxidative Stress: Pharmaceutical and Pharmacological Aspects 2018
  9. Renoprotective effect of tectorigenin glycosides isolated from Iris spuria L. (Zeal) against hyperoxaluria and hyperglycemia in NRK-49Fcells
  10. Potential Applications of NRF2 Inhibitors in Cancer Therapy
  11. Viral Induced Oxidative and Inflammatory Response in Alzheimer’s Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach
  12. Relation of Redox and Structural Alterations of Rat Skin in the Function of Chronological Aging
  13. Synthesis and Characterization of 3-(1-((3,4-Dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a Potential Antitumor Agent
  14. Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review
  15. Potential Use of Modulators of Oxidative Stress as Add-on Therapy in Patients with Anxiety Disorders
  16. 9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a Potentially Novel Antiplatelet Drug which Antagonizes the Effect of Thromboxane A2
  17. Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds
  18. Nonylphenol and Octylphenol Differently Affect Cell Redox Balance by Modulating the Nitric Oxide Signaling
  19. Oxidative Stress Induces HSP90 Upregulation on the Surface of Primary Human Endothelial Cells: Role of the Antioxidant 7,8-Dihydroxy-4-methylcoumarin in Preventing HSP90 Exposure to the Immune System
  20. In Vitro Assessment of the Effect of Antiepileptic Drugs on Expression and Function of ABC Transporters and Their Interactions with ABCC2
  21. The Role Of Oxidative Stress Modulators In Breast Cancer
  22. Antioxidant activity of phenolic compounds from extracts of Eucalyptus globulus and Melaleuca styphelioides and their protective role on D-glucose-induced hyperglycemic stress and oxalate stress in NRK-49Fcells
  23. Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?
  24. Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease
  25. Effect of Oxidative Stress on ABC Transporters: Contribution to Epilepsy Pharmacoresistance
  26. Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study
  27. Cardiovascular Mitochondrial Dysfunction Induced by Cocaine: Biomarkers and Possible Beneficial Effects of Modulators of Oxidative Stress
  28. Modulation of Oxidative Stress: Pharmaceutical and Pharmacological Aspects 2017
  29. Synthesis and evaluation of antibacterial and antioxidant activity of novel 2-phenyl-quinoline analogs derivatized at position 4 with aromatically substituted 4H-1,2,4-triazoles
  30. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells
  31. Novel indole-based melatonin analogues: Evaluation of antioxidant activity and protective effect against amyloid β-induced damage
  32. Lanthanide(III) complexes are more active inhibitors of the Fenton reaction than pure ligands
  33. Cardiovascular and Hepatic Toxicity of Cocaine: Potential Beneficial Effects of Modulators of Oxidative Stress
  34. Modulation of Oxidative Stress: Pharmaceutical and Pharmacological Aspects
  35. Redox Control of Multidrug Resistance and Its Possible Modulation by Antioxidants
  36. Modulation of neurotrophic signaling pathways by polyphenols
  37. Oxidative stress, bioelements and androgen status in testes of rats subacutely exposed to cadmium
  38. The impact of Hydrogen peroxide on structure, stability and functional properties of Human R12C mutant αA-crystallin: The imperative insights into pathomechanism of the associated congenital cataract incidence
  39. Effective attenuation of atrazine-induced histopathological changes in testicular tissue by antioxidantN-phenyl-4-aryl-polyhydroquinolines
  40. Structure–activity relationship studies of 4-methylcoumarin derivatives as anticancer agents
  41. Inhibition of Alzheimer’s BACE-1 by 2,6-dialkyl-4-chromon-3-yl-1,4-dihydropyridine-3,5-dicarboxylates
  42. Hypoglycemic activity of curcumin synthetic analogues in alloxan-induced diabetic rats
  43. Cytotoxic and multidrug resistance reversal activities of novel 1,4-dihydropyridines against human cancer cells
  44. Multiple Mechanisms of Iron-Induced Amyloid Beta-Peptide Accumulation in SHSY5Y Cells: Protective Action of Negletein
  45. Carthamus, SalviaandStachysspecies protect neuronal cells against oxidative stress-induced apoptosis
  46. In vitro evaluation of copper-chelating properties of flavonoids
  47. Chromenone and quinolinone derivatives as potent antioxidant agents
  48. 4-Methylcoumarin Derivatives with Anti-inflammatory Effects in Activated Microglial Cells
  49. Comparison of Protein Acetyltransferase Action of CRTAase with the Prototypes of HAT
  50. Isoprostanes and Neuroprostanes as Biomarkers of Oxidative Stress in Neurodegenerative Diseases
  51. Resveratrol Counteracts Inflammation in Human M1 and M2 Macrophages upon Challenge with 7-Oxo-Cholesterol: Potential Therapeutic Implications in Atherosclerosis
  52. Editorial (Thematic Issue: Synthesis, Evaluation and Pharmacological Applications of Antioxidants- Part 1)
  53. Editorial (Thematic Issue: Synthesis, Evaluation and Pharmacological Applications of Antioxidants- Part 2)
  54. Antioxidant Activity of Galantamine and Some of its Derivatives
  55. Advances in Research of Schiff-Base Metal Complexes as Potent Antioxidants
  56. Oxidized Haemoglobin–Driven Endothelial Dysfunction and Immune Cell Activation: Novel Therapeutic Targets for Atherosclerosis
  57. Reversal of multidrug resistance in cancer cells by novel asymmetrical 1,4-dihydropyridines
  58. Protection of Cells against Oxidative Stress by Nanomolar Levels of Hydroxyflavones Indicates a New Type of Intracellular Antioxidant Mechanism
  59. Comparative specificities of Calreticulin Transacetylase to O-acetyl, N-acetyl and S-acetyl derivative of 4-methylcoumarins and their inhibitory effect on AFB1-induced genotoxicity in vitro and in vivo
  60. Editorial (Hot Topic: Antioxidant Heterocyclic Compounds in Drug Discovery and Medicinal Chemistry)
  61. Biotechnology in the Production of Pharmaceutical Industry Ingredients: Amino Acids
  62. Resveratrol Prevents Dendritic Cell Maturation in Response to Advanced Glycation End Products
  63. In vitro platelet antiaggregatory properties of 4-methylcoumarins
  64. Iron reduction potentiates hydroxyl radical formation only in flavonols
  65. An efficient and convenient microwave-assisted chemical synthesis of (thio)xanthones with additional in vitro and in silico characterization
  66. Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress
  67. Antiradical and antioxidant activities of new bio-antioxidants
  68. Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice
  69. Biomarkers of Subclinical Atherosclerosis in Patients with Autoimmune Disorders
  70. In vitro characteristics of 1-phenyl-3-methyl-4-acylpyrazol-5-ones iron chelators
  71. T Lymphocyte Autoreactivity in Inflammatory Mechanisms Regulating Atherosclerosis
  72. The mechanism of antioxidant activity of IRFI005 as a synthetic hydrophilic analogue of vitamin E
  73. Normalization of deranged signal transduction in lymphocytes of COPD patients by the novel calcium channel blocker H-DHPM
  74. Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin
  75. Protein Acyltransferase Function of Purified Calreticulin: The Exclusive Role of P-Domain in Mediating Protein Acylation Utilizing Acyloxycoumarins and Acetyl CoA as the Acyl Group Donors
  76. In vitro analysis of iron chelating activity of flavonoids
  77. Advanced glycation end products of human  2 glycoprotein I modulate the maturation and function of DCs
  78. Dietary Phenolic Acids and Derivatives. Evaluation of the Antioxidant Activity of Sinapic Acid and Its Alkyl Esters
  79. Optimization of Lipase Production from Aspergillus terreus by Response Surface Methodology and Its Potential for Synthesis of Partial Glycerides Under Solvent Free Conditions
  80. Novel coumarin-based tyrosinase inhibitors discovered by OECD principles-validated QSAR approach from an enlarged, balanced database
  81. 4-Methylcoumarins as antioxidants: Scavenging of peroxyl radicals and inhibition of human low-density lipoprotein oxidation
  82. A spectroelectrochemical and chemical study on oxidation of 7,8-dihydroxy-4-methylcoumarin (DHMC) and some related compounds in aprotic medium
  83. Antioxidant properties of 4-methylcoumarins in in vitro cell-free systems
  84. In vitro interactions of coumarins with iron
  85. Structure–activity relationship of dihydroxy-4-methylcoumarins as powerful antioxidants: Correlation between experimental & theoretical data and synergistic effect
  86. β-sitosterol among other secondary metabolites of Piper galeatum shows inhibition of TNFα-induced cell adhesion molecule expression on human endothelial cells
  87. Protein acyltransferase function of purified calreticulin. Part 1: characterization of propionylation of protein utilizing propoxycoumarin as the propionyl group donor
  88. Home cage testing of delay discounting in rats
  89. Resilience and vulnerability are dose-dependently related to neonatal stressors in mice
  90. Phycocyanin liposomes for topical anti-inflammatory activity: in-vitro in-vivo studies
  91. Phycocyanin liposomes for topical anti-inflammatory activity: in-vitro in-vivo studies
  92. Inhibition of zymosan-induced kidney dysfunction by tyrphostin AG-490
  93. The Role of Calreticulin Transacetylase in the Activation of Human Platelet Nitrite Reductase by Polyphenolic Acetates
  94. Non-native glyceraldehyde-3-phosphate dehydrogenase can be an intrinsic component of amyloid structures
  95. Autoacetylation of Purified Calreticulin Transacetylase Utilizing Acetoxycoumarin as the Acetyl Group Donor
  96. Autoacetylation of Purified Calreticulin Transacetylase Utilizing Acetoxycoumarin as the Acetyl Group Donor
  97. Inhibition of Candida albicans extracellular enzyme activity by selected natural substances and their application inCandidainfection
  98. Calreticulin Transacetylase Catalyzed Activation of Rat Tracheal Smooth Muscle Cell Nitric Oxide Synthase by Acetoxycoumarins
  99. Behavioral effects of 6-bromoflavanone and 5-methoxy-6,8-dibromoflavanone as anxiolytic compounds
  100. DPPH Radical Scavenging Activity of Several Naturally Occurring Coumarins and Their Synthesized Analogs Measured by the SIA Method
  101. Protein oxidation markers in the serum and synovial fluid of psoriatic arthritis patients
  102. Antioxidant activity of 4-methylcoumarins
  103. Themed Issue:Chemistry and Biology of Antioxidants
  104. Specific oxidative stress parameters differently correlate with nailfold capillaroscopy changes and organ involvement in systemic sclerosis
  105. Antioxidant and prooxidant effects of quercetin on glyceraldehyde-3-phosphate dehydrogenase
  106. Interaction of Polyelectrolytes with Proteins, 3
  107. Synthesis of Deoxy Sugar Esters:  A Chemoenzymatic Stereoselective Approach Affording Deoxy Sugar Derivatives Also in the Form of Aldehyde
  108. Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease
  109. Helicobacter pylori EstV: Identification, Cloning, and Characterization of the First Lipase Isolated from an Epsilon-Proteobacterium
  110. A spectroelectrochemical and chemical study on oxidation of hydroxycinnamic acids in aprotic medium
  111. Effect of α-crystallin on thermal denaturation and aggregation of rabbit muscle glyceraldehyde-3-phosphate dehydrogenase
  112. Effect of infliximab on the glycosylation of IgG of patients with rheumatoid arthritis
  113. Mechanism of Thermal Aggregation of Rabbit Muscle Glyceraldehyde-3-phosphate Dehydrogenase†
  114. Oxidative stress parameters in different systemic rheumatic diseases
  115. Preface
  116. Inhibition of Candida rugosa lipase by saponins, flavonoids and alkaloids
  117. Propionibacterium acnes GehA lipase, an enzyme involved in acne development, can be successfully inhibited by defined natural substances
  118. Parameters of oxidative stress status in healthy subjects: their correlations and stability after sample collection
  119. Interaction of Polyanions with Basic Proteins, 2
  120. Long-term effects of lonidamine on mouse testes
  121. Lonidamine transiently affects spermatogenesis in pubertal CD1 mice
  122. Preface: male infertility, from contraception to therapy
  123. Identification of a carboxylesterase-producingRhodococcussoil isolate
  124. Ibogaine reduces organ colonization in murine systemic and gastrointestinal Candida albicans infections
  125. Atractylis gummifera L. poisoning: an ethnopharmacological review
  126. Evaluation of the antioxidant activity of flavonoids by “ferric reducing antioxidant power” assay and cyclic voltammetry
  127. Activation and inhibition of Candida rugosa and Bacillus-related lipases by saturated fatty acids, evaluated by a new colorimetric microassay
  128. Hypochlorite scavenging activity of flavonoids
  129. Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines
  130. Preface
  131. Development of a new assay for the screening of hypochlorous acid scavengers based on reversed-phase high-performance liquid chromatography
  132. Indazole carboxylic acids in male contraception
  133. Lipocalin type prostaglandin D-synthase: which role in male fertility?
  134. Recent studies on lonidamine, the lead compound of the antispermatogenic indazol-carboxylic acids
  135. The controversial efficacy of vitamin E for human male infertility
  136. Antimicrobial and Anti-Lipase Activity of Quercetin and its C2-C16 3-O-Acyl-Esters
  137. Corneal Toxicity of Xylazine and Clonidine, in Combination with Ketamine, in the Rat
  138. Analgesic properties of Epilobium angustifolium, evaluated by the hot plate test and the writhing test
  139. Anti-proliferative effect on a prostatic epithelial cell line (PZ-HPV-7) by Epilobium angustifolium L.
  140. Inhibition of calcium oxalate precipitation by bile salts
  141. Analysis of lonidamine in rat serum and testis by high performance liquid chromatography
  142. Antidenaturant drugs for cataract and other condensation diseases
  143. In vitro evaluation of antioxidant activity by electrophoresis and high performance liquid chromatography
  144. Antimicrobial investigation of semipurified fractions of Ginkgo biloba leaves
  145. Stimulation of guinea pig isolated atria by aflatoxins
  146. Effects of lonidamine on testicular and epididymal proteins in the rat☆
  147. AFLATOXINS INHIBIT PROLACTIN SECRETION BY RAT PITUITARY CELLS IN CULTURE
  148. Simultaneous determination of hydrocortisone, dexamethasone, indomethacin, phenylbutazone and oxyphenbutazone in equine serum by high-performance liquid chromatography
  149. Micropurification of β- and γ-crystallins from rabbit aqueous humor
  150. Development of an in vitro Assay for the Screening of Substances Capable of Dissolving Calcium Oxalate Crystals
  151. Development of an enzyme-linked immunosorbent assay, using a monoclonal antibody against α2-macroglobulin, for the diagnosis of systemic lupus erythematosus
  152. Changes in concanavalin A-reactive proteins in neurological disorders
  153. Inhibition of Protein Denaturation by Fatty Acids, Bile Salts and Other Natural Substances: A New Hypothesis for the Mechanism of Action of Fish Oil in Rheumatic Diseases.
  154. Development of a Turbidimetric Assay to Study the Effect of Urinary Components on Calcium Oxalate Precipitation
  155. Development of an HPLC Assay to Study the Effect of Endogenous and Exogenous Substances on Heat-Induced Aggregation of Human Serum Albumin
  156. Response of α2-Macroglobulin Messenger Ribonucleic Acid Expression to Acute Inflammation in the Testis is Different from the Response in the Liver and Brain1
  157. Abnormal glycosylation of ?2-macroglobulin, a non-acute-phase protein, in patients with autoimmune diseases
  158. The Use of High-Performance Electrophoresis Chromatography for the Micropurification of Cerebrospinal Fluid Proteins in the Rat
  159. Changes of immunoreactivity in ?1-antitrypsin in patients with autoimmune diseases
  160. Facilitating Effect of Amphetamine and Harmaline on Blood Pressure Response to Biogenic Amines in Rats
  161. In Vitro Antiproliferative Activity of Petiveria Alliacea L. on Several Tumor Cell Lines
  162. Persea Indica: General Pharmacological Effects of the Total Extract
  163. Regulation of Sertoli Cell α2-Macroglobulin and Clusterin (SGP-2) Secretion by Peritubular Myoid Cells1