All Stories

  1. Beyond Statistical Significance: Methodological Fragility and Censoring Bias in the 5-Year Update of CheckMate 743
  2. Dental Pulp Stem Cell-Derived Organoids: Advancing the Development of 3D Structures
  3. “WEE”ding Out Resistance to Osimertinib in the “ARID”1A-Mutated Badlands
  4. Reducing clinical target volume margins for multifocal glioblastoma: a multi-institutional analysis of patterns of recurrence and treatment response
  5. Encouraging Fussy Eaters in EGFR-Mutated Lung Cancer
  6. Based on the Real-World Results From Australia, Immunotherapy Is Not a Good Option for Patients With Mesothelioma
  7. Impact of Center Volume on Cardiopulmonary and Mortality Outcomes after Immune-Checkpoint Inhibitors for Cancer: A Systematic Review and Meta-Analysis
  8. The Impact of 3D Nichoids and Matrix Stiffness on Primary Malignant Mesothelioma Cells
  9. Editorial: Editor's challenge: Dr. Luciano Mutti - what is the true impact of ICIs on survival in the treatment of thoracic malignancies?
  10. Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo
  11. Editorial: Prognostic factors in non-small cell lung cancer
  12. Intratumor microbiota as a novel potential prognostic indicator in mesothelioma
  13. The role of brain radiotherapy for EGFR- and ALK-positive non-small-cell lung cancer with brain metastases: a review
  14. The function and clinical implication of YTHDF1 in the human system development and cancer
  15. Analysis of new treatments proposed for malignant pleural mesothelioma raises concerns about the conduction of clinical trials in oncology
  16. European Respiratory Society guideline on various aspects of quality in lung cancer care
  17. Neuro–Immune Interactions in Severe COVID-19 Infection
  18. The function and clinical implication of circular RNAs in lung cancer
  19. PD-1/PD-L1 immune-checkpoint blockade induces immune effector cell modulation in metastatic non-small cell lung cancer patients: A single-cell flow cytometry approach
  20. Identification and Validation of Long Non-Coding RNA LCIIAR as a Biomarker in LUAD
  21. Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations
  22. Abemaciclib for malignant pleural mesothelioma
  23. Crossing survival curves of KEYNOTE-177 illustrate the rationale behind combining immune checkpoint inhibition with chemotherapy
  24. A Drug Screening Revealed Novel Potential Agents against Malignant Pleural Mesothelioma
  25. Over-Expression of Long Non-Coding RNA-AC099850.3 Correlates With Tumor Progression and Poor Prognosis in Lung Adenocarcinoma
  26. Comparison of 3 Randomized Clinical Trials of Frontline Therapies for Malignant Pleural Mesothelioma
  27. Comparing Addition of Radiotherapy in EGFR- and ALK-Positive NSCLC With Brain Metastases: Are We Evaluating the Optimal End Point?
  28. CONFIRM trial: what is the real efficacy of second-line immunotherapy in mesothelioma?
  29. Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer
  30. Distinctive Role of the Systemic Inflammatory Profile in Non-Small-Cell Lung Cancer Younger and Elderly Patients Treated with a PD-1 Immune Checkpoint Blockade: A Real-World Retrospective Multi-Institutional Analysis
  31. CDK4, CDK6/cyclin-D1 Complex Inhibition and Radiotherapy for Cancer Control: A Role for Autophagy
  32. Liquid Biopsies from Pleural Effusions and Plasma from Patients with Malignant Pleural Mesothelioma: A Feasibility Study
  33. Identification of Overexpressed Genes in Malignant Pleural Mesothelioma
  34. Protein disulfide isomerase A1 regulates breast cancer cell immunorecognition in a manner dependent on redox state
  35. HLA Expression Correlates to the Risk of Immune Checkpoint Inhibitor-Induced Pneumonitis
  36. HLA-B*44 and C*01 Prevalence Correlates with Covid19 Spreading across Italy
  37. Immunotherapy for mesothelioma: a critical review of current clinical trials and future perspectives
  38. Tumour Treating Fields for mesothelioma
  39. Sirtuin Family Members Selectively Regulate Autophagy in Osteosarcoma and Mesothelioma Cells in Response to Cellular Stress
  40. What can independent research for mesothelioma achieve to treat this orphan disease?
  41. The Biochemical Role of the Human NEIL1 and NEIL3 DNA Glycosylases on Model DNA Replication Forks
  42. When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?
  43. BAP1 Status Determines the Sensitivity of Malignant Mesothelioma Cells to Gemcitabine Treatment
  44. ERS Statement on harmonised standards for lung cancer registration and lung cancer services in Europe
  45. p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification
  46. Scientific Advances and New Frontiers in Mesothelioma Therapeutics
  47. A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma
  48. Surgery for malignant pleural mesothelioma: an international guidelines review
  49. Insight into glucocorticoid receptor signalling through interactome model analysis
  50. Immunotherapy advances for mesothelioma treatment
  51. Promising investigational drug candidates in phase I and phase II clinical trials for mesothelioma
  52. Correction: MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma
  53. Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism
  54. Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia
  55. The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells
  56. Current and prospective pharmacotherapies for the treatment of pleural mesothelioma
  57. Mesothelin promoter variants are associated with increased soluble mesothelin-related peptide levels in asbestos-exposed individuals
  58. Anti-CTLA-4 therapy for malignant mesothelioma
  59. Inhibition of the platelet-derived growth factor receptor beta (PDGFRB) using gene silencing, crenolanib besylate, or imatinib mesylate hampers the malignant phenotype of mesothelioma cell lines
  60. Switching off malignant mesothelioma: exploiting the hypoxic microenvironment
  61. New standard for assessing asbestos exposure and its consequences?
  62. Repurposing atovaquone: Targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells
  63. The role of microenvironment and immunity in drug response in leukemia
  64. Targeting hypoxic response for cancer therapy
  65. Tremelimumab for the treatment of malignant mesothelioma
  66. Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo
  67. Expression status of candidate genes in mesothelioma tissues and cell lines
  68. A Common Polymorphism Within MSLN Affects miR-611 Binding Site and Soluble Mesothelin Levels in Healthy People
  69. “Cancer Bio-Immunotherapy in Siena”: Eleventh Meeting of the Network Italiano per la Bioterapia dei Tumori (NIBIT), Siena, Italy, October 17–19, 2013
  70. MSLN Gene Silencing Has an Anti-Malignant Effect on Cell Lines Overexpressing Mesothelin Deriving from Malignant Pleural Mesothelioma
  71. Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells
  72. Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial
  73. Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo
  74. Therapies currently in Phase II trials for malignant pleural mesothelioma
  75. Preclinical Demonstration of Synergistic Active Nutrients/Drug (AND) Combination as a Potential Treatment for Malignant Pleural Mesothelioma
  76. PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1
  77. Response to chemotherapy is predictive in relation to longer overall survival in an individual patient combined-analysis with pleural mesothelioma
  78. Epigallocatechin-3-gallate induces mesothelioma cell deathviaH2O2−dependent T-type Ca2+channel opening
  79. Perifosine as a Potential Novel Anti-Cancer Agent Inhibits EGFR/MET-AKT Axis in Malignant Pleural Mesothelioma
  80. Circulating tumor cells as a diagnostic test for malignant pleural mesothelioma
  81. Sustained Expression of Steroid Receptor Coactivator SRC-2/TIF-2 is Associated with Better Prognosis in Malignant Pleural Mesothelioma
  82. Expression and regulation of B7-H3 immunoregulatory receptor, in human mesothelial and mesothelioma cells: Immunotherapeutic implications
  83. Estrogen Receptor β Exerts Tumor Repressive Functions in Human Malignant Pleural Mesothelioma via EGFR Inactivation and Affects Response to Gefitinib
  84. Will Antiangiogenic Agents be a Future for Mesothelioma Therapy?
  85. Comparison between Plasma and Serum Osteopontin Levels: Usefulness in Diagnosis of Epithelial Malignant Pleural Mesothelioma
  86. Translational therapies for malignant pleural mesothelioma
  87. Gefitinib Targets EGFR Dimerization and ERK1/2 Phosphorylation to Inhibit Pleural Mesothelioma Cell Proliferation
  88. MicroRNA Signature of Malignant Mesothelioma with Potential Diagnostic and Prognostic Implications
  89. In vitro and in vivo characterization of highly purified Human Mesothelioma derived cells
  90. Risk of malignant pleural mesothelioma and polymorphisms in genes involved in the genome stability and xenobiotics metabolism
  91. Guidelines of the European Respiratory Society and the European Society of Thoracic Surgeons for the management of malignant pleural mesothelioma
  92. Malignant pleural mesothelioma: current treatments and emerging drugs
  93. Estrogen Receptor-  Affects the Prognosis of Human Malignant Mesothelioma
  94. Taurolidine and oxidative stress: a rationale for local treatment of mesothelioma
  95. In Arrayed Ranks: Array Technology in the Study of Mesothelioma
  96. Simian virus 40 sequences in blood specimens from healthy individuals of Casale Monferrato, an industrial town with a history of asbestos pollution
  97. Ranpirnase and its potential for the treatment of unresectable malignant mesothelioma
  98. Genetic susceptibility to malignant pleural mesothelioma and other asbestos-associated diseases
  99. The therapeutic potential of the novel ribonuclease ranpirnase (Onconase®) in the treatment of malignant mesothelioma
  100. Genetic susceptibility to malignant mesothelioma and exposure to asbestos: The influence of the familial factor
  101. Imatinib Mesylate Enhances Therapeutic Effects of Gemcitabine in Human Malignant Mesothelioma Xenografts
  102. Is dronedarone effective for the prevention of recurrent atrial fibrillation?
  103. Bortezomib Inhibits Nuclear Factor- B Dependent Survival and Has Potent In vivo Activity in Mesothelioma
  104. BCL-2 family regulation by the 20S proteasome inhibitor bortezomib
  105. Clinical Significance of Serum Mesothelin in Patients with Mesothelioma and Lung Cancer
  106. Preliminary data suggestive of a novel translational approach to mesothelioma treatment: imatinib mesylate with gemcitabine or pemetrexed
  107. Polymorphisms of glutathione-S-transferase M1 and manganese superoxide dismutase are associated with the risk of malignant pleural mesothelioma
  108. Erionite and asbestos differently cause transformation of human mesothelial cells
  109. Negative results of an Italian Group for Mesothelioma (G.I.Me.) pilot study of single-agent imatinib mesylate in malignant pleural mesothelioma
  110. Current treatment options and biology of peritoneal mesothelioma: meeting summary of the first NIH peritoneal mesothelioma conference
  111. A Molecular Epidemiology Case Control Study on Pleural Malignant Mesothelioma
  112. SV40-Dependent AKT Activity Drives Mesothelial Cell Transformation after Asbestos Exposure
  113. New Agents in the Management of Advanced Mesothelioma
  114. Raltitrexed–Oxaliplatin combination chemotherapy is inactive as second-line treatment for malignant pleural mesothelioma patients
  115. Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase
  116. SV40 Enhances the Risk of Malignant Mesothelioma among People Exposed to Asbestos: A Molecular Epidemiologic Case-Control Study
  117. Malignant Mesothelioma as both a challenge and an opportunity
  118. SV40 and human brain tumors
  119. Simian virus 40 and malignant mesothelioma (Review)
  120. Intrapleural interleukin-2 induces nitric oxide production in pleural effusions from malignant mesothelioma: A possible mechanism of interleukin-2-mediated cytotoxicity?
  121. Synergistic effect of the anti-HER-2/neu antibody and cisplatin in immortalized and primary mesothelioma cell lines
  122. Cancer testis antigens expression in mesothelioma: role of DNA methylation and bioimmunotherapeutic implications
  123. The Presence of Simian-Virus 40 Sequences in Mesothelioma and Mesothelial Cells Is Associated with High Levels of Vascular Endothelial Growth Factor
  124. Expression of glycoprotein 90K in human malignant pleural mesothelioma: correlation with patient survival
  125. SV40 replication in human mesothelial cells induces HGF/Met receptor activation: A model for viral-related carcinogenesis of human malignant mesothelioma
  126. Basic fibroblast growth factor in mesothelioma pleural effusions: Correlation with patient survival and angiogenesis
  127. Palliative and therapeutic activity of IL-2 immunotherapy in unresectable malignant pleural mesothelioma with pleural effusion
  128. Association of SV40 with human tumours
  129. Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma
  130. Prognostic significance of presence and reduplication of basal lamina in malignant pleural mesothelioma
  131. Simian virus-40 sequences are a negative prognostic cofactor in patients with malignant pleural mesothelioma
  132. Simian virus-40 sequences are a negative prognostic cofactor in patients with malignant pleural mesothelioma
  133. Interleukin-2 induces cell cycle perturbations leading to cell growth inhibition and death in malignant mesothelioma cells in vitro
  134. Establishment of four new mesothelioma cell lines: characterization by ultrastructural and immunophenotypic analysis
  135. Primary human mesothelioma cells express class II MHC, ICAM-1 and B7–2 and can present recall antigens to autologous blood lymphocytes
  136. New Target Therapies for Malignant Mesothelioma