All Stories

  1. Bacterial toxins induce non-canonical migracytosis to aggravate acute inflammation

    Article • Cell Discovery, November 2024, Springer Science + Business Media

    Liang Tao

  2. De novo design of mini-protein binders broadly neutralizing Clostridioides difficile toxin B variants

    Article • Nature Communications, October 2024, Springer Science + Business Media

    Liang Tao

  3. Identification of a hemorrhagic determinant in Clostridioides difficile TcdA and Paeniclostridium sordellii TcsH

    Article • Microbiology Spectrum, June 2024, ASM Journals

    Liang Tao

  4. Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin

    Article • Nature Communications, March 2024, Springer Science + Business Media

    Liang Tao

  5. Fight or flee, a vital choice for Clostridioides difficile

    Article • mLife, February 2024, Tsinghua University Press

    Liang Tao

  6. Structural dynamics of the CROPs domain control stability and toxicity of Paeniclostridium sordellii lethal toxin

    Article • Nature Communications, December 2023, Springer Science + Business Media

    Liang Tao

  7. Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth

    Article • PLoS Biology, November 2023, PLOS

    Liang Tao

  8. Topological links in predicted protein complex structures reveal limitations of AlphaFold

    Article • Communications Biology, October 2023, Springer Science + Business Media

    Liang Tao

  9. Three-dimensional printing of soft hydrogel electronics

    Article • Nature Electronics, December 2022, Springer Science + Business Media

    Liang Tao

  10. LDLR, LRP1, and Megalin redundantly participate in the uptake of Clostridium novyi alpha-toxin

    Article • Communications Biology, September 2022, Springer Science + Business Media

    Liang Tao

  11. Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells

    Article • STAR Protocols, September 2022, Elsevier

    Liang Tao

  12. Paeniclostridium sordellii hemorrhagic toxin targets TMPRSS2 to induce colonic epithelial lesions

    Article • Nature Communications, July 2022, Springer Science + Business Media

    Liang Tao

  13. Distinctive signatures of pathogenic and antibiotic resistant potentials in the hadal microbiome

    Article • Environmental Microbiome, April 2022, Springer Science + Business Media

    Liang Tao

  14. An Atypical Case of Monomicrobial Clostridioides difficile Septicemia With No Gastrointestinal Manifestations

    Article • Frontiers in Cellular and Infection Microbiology, March 2022, Frontiers

    Liang Tao

  15. TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile

    Article • Cell, March 2022, Elsevier

    Liang Tao

  16. Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection

    Article • Nature Communications, June 2021, Springer Science + Business Media

    Liang Tao

  17. Sulfated glycosaminoglycans and low-density lipoprotein receptor mediate the cellular entry of Clostridium novyi alpha-toxin

    Article • BDJ, May 2021, Springer Science + Business Media

    Liang Tao

  18. Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology

    Article • PLoS Pathogens, January 2021, PLOS

    Liang Tao

  19. Receptor Binding Domains of TcdB from Clostridioides difficile for Chondroitin Sulfate Proteoglycan-4 and Frizzled Proteins Are Functionally Independent and Additive

    Article • Toxins, November 2020, MDPI AG

    Liang Tao

  20. Subtyping analysis reveals new variants and accelerated evolution of Clostridioides difficile toxin B

    Article • Communications Biology, July 2020, Springer Science + Business Media

    Liang Tao

  21. Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells

    Article • Nature Microbiology, June 2019, Springer Science + Business Media

    Liang Tao

  22. Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

    Article • PLoS Biology, November 2018, PLOS

    Liang Tao

  23. Structural insight into Wnt signaling inhibition by Clostridium difficile toxin B

    Article • European Journal of Biochemistry, November 2018, Wiley

    Liang Tao

  24. Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B

    Article • Science, May 2018, American Association for the Advancement of Science

    Liang Tao

  25. Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium

    Article • Cell Host & Microbe, February 2018, Elsevier

    Liang Tao

  26. Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC

    Article • Nature Communications, November 2017, Springer Science + Business Media

    Liang Tao

  27. Engineered botulinum neurotoxin B with improved efficacy for targeting human receptors

    Article • Nature Communications, July 2017, Springer Science + Business Media

    Liang Tao

  28. Strain-Dependent Recognition of a Unique Degradation Motif by ClpXP in Streptococcus mutans

    Article • mSphere, December 2016, ASM Journals

    Indranil Biswas, Liang Tao

  29. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B

    Article • Nature, September 2016, Springer Science + Business Media

    Liang Tao

  30. Degradation of SsrA-tagged proteins in streptococci

    Article • Microbiology, April 2015, Society for General Microbiology

    Liang Tao

  31. 157. Variations in VAMP1 across vertebrates suggest a potential selective pressure from botulinum neurotoxins

    Article • Toxicon, January 2015, Elsevier

    Liang Tao

  32. Widespread Sequence Variations in VAMP1 across Vertebrates Suggest a Potential Selective Pressure from Botulinum Neurotoxins

    Article • PLoS Pathogens, July 2014, PLOS

    Liang Tao

  33. ClpL Is Required for Folding of CtsR in Streptococcus mutans

    Article • Journal of Bacteriology, November 2012, ASM Journals

    Indranil Biswas, Liang Tao

  34. CtsR Regulation in mcsAB-Deficient Gram-Positive Bacteria

    Article • Journal of Bacteriology, January 2012, ASM Journals

    Liang Tao

  35. Sulfhydryl compounds reduce Staphylococcus aureus biofilm formation by inhibiting PIA biosynthesis

    Article • FEMS Microbiology Letters, January 2011, Oxford University Press (OUP)

    Liang Tao

  36. Alternative Sigma Factor σH Modulates Prophage Integration and Excision in Staphylococcus aureus

    Article • PLoS Pathogens, May 2010, PLOS

    Liang Tao