All Stories

  1. Use of electronic cigarettes and asthma across the lifespan

    Article • Journal of Allergy and Clinical Immunology, July 2026, Elsevier

    Dr Laura Elise Crotty Alexander

  2. Impact of e-cigarette vaping on the immune system across the body

    Article • Physiological Reviews, January 2026, American Physiological Society

    Dr Laura Elise Crotty Alexander

  3. Effects of Inhaled Tobacco and Cannabis Co-Use on Respiratory Health and Tobacco Cessation: An Official American Thoracic Society Research Statement

    Article • American Journal of Respiratory and Critical Care Medicine, November 2025, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  4. Perceptions of Health Risks and Accessibility: A Social Media-Based Pilot Study of Factors Influencing Use of Vaping and Combustible Tobacco Products

    Article • International Journal of Environmental Research and Public Health, May 2025, MDPI AG

    Dr Laura Elise Crotty Alexander

  5. Cannabis consumption conundrum: weighing the risks of vaping and smoking

    Article • AJP Lung Cellular and Molecular Physiology, May 2025, American Physiological Society

    Dr Laura Elise Crotty Alexander

  6. A Pilot Study on the Impact of Vaping on Adolescent Lung Function and Nasal Epithelial Gene Expression

    Article • American Journal of Respiratory Cell and Molecular Biology, May 2025, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  7. Factors driving switching from vaping of e-cigarettes to smoking tobacco and initiation of multi-inhalant use

    Article • March 2025, Cold Spring Harbor Laboratory Press

    Dr Laura Elise Crotty Alexander

  8. Dual Use of Cannabis with Tobacco Is Associated with Increased Sugary Food and Drink Intake in Young People

    Article • International Journal of Environmental Research and Public Health, August 2024, MDPI AG

    Dr Laura Elise Crotty Alexander

  9. Assessing Barriers to Implementation of Machine Learning and Artificial Intelligence–Based Tools in Critical Care: Web-Based Survey Study

    Article • JMIR Perioperative Medicine, January 2023, JMIR Publications Inc.

    Dr Laura Elise Crotty Alexander

  10. A Problem for Generations: Impact of E-Cigarette Type on Immune Homeostasis

    Article • American Journal of Respiratory and Critical Care Medicine, November 2022, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  11. Assessing Barriers to Implementation of Machine Learning and Artificial Intelligence–Based Tools in Critical Care: Web-Based Survey Study (Preprint)

    Article • July 2022, JMIR Publications Inc.

    Dr Laura Elise Crotty Alexander

  12. Beware, vaping e-cigarettes around children is adversely impacting their lung health

    Article • Thorax, January 2022, BMJ

    Dr Laura Elise Crotty Alexander

  13. Deleterious Association of Inhalant Use on Sleep Quality during the COVID-19 Pandemic

    Article • International Journal of Environmental Research and Public Health, December 2021, MDPI AG

    Dr Laura Elise Crotty Alexander

  14. Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury

    Article • AJP Lung Cellular and Molecular Physiology, May 2021, American Physiological Society

    Dr Laura Elise Crotty Alexander

  15. Vaping disrupts ventilation-perfusion matching in asymptomatic users

    Article • Journal of Applied Physiology, February 2021, American Physiological Society

    Dr Laura Elise Crotty Alexander

  16. Increased peripheral blood neutrophil activation phenotypes and NETosis in critically ill COVID-19 patients

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Dr Laura Elise Crotty Alexander

  17. Cigarette Smoke Exposure Promotes Virulence of Pseudomonas aeruginosa and Induces Resistance to Neutrophil Killing

    Article • Infection and Immunity, October 2020, ASM Journals

    Dr Laura Elise Crotty Alexander

  18. Effects of e‐cigarettes and vaping devices on cardiac and pulmonary physiology

    Article • The Journal of Physiology, October 2020, Wiley

    Dr Laura Elise Crotty Alexander

  19. Vaping and e-cigarette use. Mysterious lung manifestations and an epidemic

    Article • Current Opinion in Immunology, October 2020, Elsevier

    Dr Laura Elise Crotty Alexander

  20. Is Increased Sleep Responsible for Reductions in Myocardial Infarction During the COVID-19 Pandemic?

    Article • The American Journal of Cardiology, September 2020, Elsevier

    Dr Laura Elise Crotty Alexander

  21. Reply: E-Cigarette, or Vaping, Product Use–associated Lung Injury: A Response to Perez and Crotty Alexander

    Article • Annals of the American Thoracic Society, July 2020, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  22. What are the mechanisms underlying vaping-induced lung injury?

    Article • Journal of Clinical Investigation, May 2020, American Society for Clinical Investigation

    Dr Laura Elise Crotty Alexander

  23. Why Is Vaping Going Up in Flames?

    Article • Annals of the American Thoracic Society, May 2020, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  24. Reply to Letter to the Editor: “Comment on ‘E-cigarette use increases susceptibility to bacterial infection by impairment of human neutrophil chemotaxis, phagocytosis, and NET formation’”

    Article • AJP Cell Physiology, March 2020, American Physiological Society

    Dr Laura Elise Crotty Alexander

  25. E-cigarette use increases susceptibility to bacterial infection by impairment of human neutrophil chemotaxis, phagocytosis, and NET formation

    Article • AJP Cell Physiology, January 2020, American Physiological Society

    Dr Laura Elise Crotty Alexander

  26. Use of Electronic Cigarettes with Conventional Tobacco Is Associated with Decreased Sleep Quality in Women

    Article • American Journal of Respiratory and Critical Care Medicine, December 2019, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  27. Human Eosinophils Express a Distinct Gene Expression Program in Response to IL-3 Compared with Common β-Chain Cytokines IL-5 and GM-CSF

    Article • The Journal of Immunology, June 2019, The American Association of Immunologists

    Dr Laura Elise Crotty Alexander

  28. Recommendations for the Appropriate Structure, Communication, and Investigation of Tobacco Harm Reduction Claims. An Official American Thoracic Society Policy Statement

    Article • American Journal of Respiratory and Critical Care Medicine, October 2018, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  29. How to manage head and neck emergencies in the ICU

    Article • Annals of the American Thoracic Society, June 2018, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  30. Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice

    Article • AJP Regulatory Integrative and Comparative Physiology, June 2018, American Physiological Society

    Dr Laura Elise Crotty Alexander

  31. Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and α-7 nicotinic acetylcholine receptor in female CD-1 mice

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, July 2017, Elsevier

    Dr Laura Elise Crotty Alexander

  32. Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney

    Article • AJP Renal Physiology, April 2017, American Physiological Society

    Dr Laura Elise Crotty Alexander

  33. Hypoxia-inducible factor-1α inhibition modulates airway hyperresponsiveness and nitric oxide levels in a BALB/c mouse model of asthma

    Article • Clinical Immunology, March 2017, Elsevier

    Dr Laura Elise Crotty Alexander

  34. Cigarette smoking causes epigenetic changes associated with cardiorenal fibrosis

    Article • Physiological Genomics, December 2016, American Physiological Society

    Dr Laura Elise Crotty Alexander

  35. HIF2α–arginase axis is essential for the development of pulmonary hypertension

    Article • Proceedings of the National Academy of Sciences, July 2016, Proceedings of the National Academy of Sciences

    Dr Laura Elise Crotty Alexander

  36. Global state of tobacco use: summary from the American Thoracic Society International Conference 2016

    Article • Journal of Thoracic Disease, July 2016, AME Publishing Company

    Dr Laura Elise Crotty Alexander

  37. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria

    Article • Journal of Molecular Medicine, January 2016, Springer Science + Business Media

    Dr Laura Elise Crotty Alexander

  38. Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines

    Article • Oral Oncology, January 2016, Elsevier

    Dr Laura Elise Crotty Alexander

  39. Inflammatory Diseases of the Lung Induced by Conventional Cigarette Smoke

    Article • CHEST Journal, November 2015, Elsevier

    Dr Laura Elise Crotty Alexander

  40. The Need for More E-Cigarette Data: A Call to Action

    Article • American Journal of Respiratory and Critical Care Medicine, August 2015, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  41. The Civil Liberty of Smoking Cigarettes

    Article • CHEST Journal, July 2015, Elsevier

    Dr Laura Elise Crotty Alexander

  42. Analysis of the Effects of Cigarette Smoke on Staphylococcal Virulence Phenotypes

    Article • Infection and Immunity, March 2015, ASM Journals

    Dr Laura Elise Crotty Alexander

  43. Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression

    Article • Journal of Molecular Medicine, August 2014, Springer Science + Business Media

    Dr Laura Elise Crotty Alexander

  44. Epidermal Deletion of HIF-2α Stimulates Wound Closure

    Article • Journal of Investigative Dermatology, March 2014, Elsevier

    Dr Laura Elise Crotty Alexander

  45. Myeloid Cell Sirtuin-1 Expression Does Not Alter Host Immune Responses to Gram-Negative Endotoxemia or Gram-Positive Bacterial Infection

    Article • PLOS One, December 2013, PLOS

    Dr Laura Elise Crotty Alexander

  46. Leukostasis-Related Diffuse Alveolar Hemorrhage in the Setting of Advancing Chronic Lymphocytic Leukemia

    Article • CHEST Journal, October 2013, Elsevier

    Dr Laura Elise Crotty Alexander

  47. Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model

    Article • Clinical Immunology, April 2013, Elsevier

    Dr Laura Elise Crotty Alexander

  48. Hypoxia Inducible Factor (HIF) Alpha Subunits Modulate Eosinophil Migration, Oxidative Burst, and Degranulation

    Article • Journal of Allergy and Clinical Immunology, February 2013, Elsevier

    Dr Laura Elise Crotty Alexander

  49. Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function

    Article • Journal of Molecular Medicine, December 2012, Springer Science + Business Media

    Dr Laura Elise Crotty Alexander

  50. Analysis Of The Role Of Hypoxia Inducible Factor-1± In Eosinophil Function And Allergic Inflammatory Airways Disease

    Article • May 2012, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  51. Erratum to: Rescuing of deficient killing and phagocytic activities of macrophages derived from non-obese diabetic mice by treatment with geldanamycin or heat shock: potential clinical implications

    Article • Cell Stress and Chaperones, July 2011, Springer Science + Business Media

    Dr Laura Elise Crotty Alexander

  52. Rescuing of deficient killing and phagocytic activities of macrophages derived from non-obese diabetic mice by treatment with geldanamycin or heat shock: potential clinical implications

    Article • Cell Stress and Chaperones, May 2011, Springer Science + Business Media

    Dr Laura Elise Crotty Alexander

  53. The Role Of Hypoxia Inducible Factor-Alpha Subunits In Allergic Inflammatory Airways Disease

    Article • May 2011, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  54. Staphylococcus epidermidis Antimicrobial δ-Toxin (Phenol-Soluble Modulin-γ) Cooperates with Host Antimicrobial Peptides to Kill Group A Streptococcus

    Article • PLOS One, January 2010, PLOS

    Dr Laura Elise Crotty Alexander

  55. M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment

    Article • Journal of Molecular Medicine, December 2009, Springer Science + Business Media

    Dr Laura Elise Crotty Alexander

  56. Group A Streptococcal Pilus Proteinspy0128Stimulates Host Inflammatory Responses, Leading to Decreased Virulence in Pneumonia and Necrotizing Fasciitis.

    Article • April 2009, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  57. Changes in Bactericidal Capacity of Macrophages in Response to Fever.

    Article • April 2009, American Thoracic Society

    Dr Laura Elise Crotty Alexander

  58. Models for CNS Malignancies

    Article • January 2005, Wiley

    Dr Laura Elise Crotty Alexander

  59. Design of Soluble Recombinant T Cell Receptors for Antigen Targeting and T Cell Inhibition

    Article • Journal of Biological Chemistry, November 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Laura Elise Crotty Alexander

  60. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

    Article • Blood, November 2002, American Society of Hematology

    Dr Laura Elise Crotty Alexander

  61. Generation of anti-idiotypic reagents in the EGFRvIII tumor-associated antigen system

    Article • Medical Oncology, February 2002, Springer Science + Business Media

    Dr Laura Elise Crotty Alexander

  62. Dendritic Cells Pulsed with a Tumor-specific Peptide Induce Long-lasting Immunity and Are Effective against Murine Intracerebral Melanoma

    Article • Neurosurgery, January 2002, Wolters Kluwer Health

    Dr Laura Elise Crotty Alexander

  63. Dendritic Cells Pulsed with a Tumor-specific Peptide Induce Long-lasting Immunity and Are Effective against Murine Intracerebral Melanoma

    Article • Neurosurgery, January 2002, Wolters Kluwer Health

    Dr Laura Elise Crotty Alexander

  64. Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors

    Article • Proceedings of the National Academy of Sciences, June 2000, Proceedings of the National Academy of Sciences

    Dr Laura Elise Crotty Alexander

  65. Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma

    Article • Journal of Neuroimmunology, February 2000, Elsevier

    Dr Laura Elise Crotty Alexander