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  1. KIF5B plays important roles in dendritic spine plasticity and dendritic localization of PSD95 and FMRP in the mouse cortex in vivo

    Article • Cell Reports, March 2024, Elsevier

    Dr Kwok-On Lai

  2. The translation initiating factor eIF4E and arginine methylation underlie G3BP1 function in dendritic spine development of neurons

    Article • Journal of Biological Chemistry, August 2023, Elsevier

    Dr Kwok-On Lai

  3. Symposia

    Article • Journal of Neurochemistry, August 2022, Wiley

    Dr Kwok-On Lai

  4. Understanding how kinesin motor proteins regulate postsynaptic function in neuron

    Article • European Journal of Biochemistry, December 2021, Wiley

    Dr Kwok-On Lai

  5. Activity and Function of the PRMT8 Protein Arginine Methyltransferase in Neurons

    Article • Life, October 2021, MDPI AG

    Dr Kwok-On Lai

  6. m6A RNA methylation-dependent APC translation is required for local translation of beta-actin and axon development

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Dr Kwok-On Lai

  7. The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation

    Article • Cell Reports, June 2020, Elsevier

    Dr Kwok-On Lai

  8. Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells

    Article • Molecular Autism, May 2020, Springer Science + Business Media

    Dr Kwok-On Lai

  9. The epilepsy and intellectual disability-associated protein TBC1D24 regulates the maintenance of excitatory synapses and animal behaviors

    Article • PLoS Genetics, January 2020, PLOS

    Dr Kwok-On Lai

  10. Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

    Article • eLife, January 2020, eLife

    Dr Kwok-On Lai

  11. Application of Human-Induced Pluripotent Stem Cells (hiPSCs) to Study Synaptopathy of Neurodevelopmental Disorders

    Article • Developmental Neurobiology, October 2018, Wiley

    Dr Kwok-On Lai

  12. Methods to Study the Signal Transduction of the Surface Receptor Tyrosine Kinase TrkB in Neurons

    Article • December 2017, Springer Science + Business Media

    Dr Kwok-On Lai

  13. Cdk5-dependent phosphorylation of liprinα1 mediates neuronal activity-dependent synapse development

    Article • Proceedings of the National Academy of Sciences, July 2017, Proceedings of the National Academy of Sciences

    Dr Kwok-On Lai

  14. Determination of dendritic spine morphology by the striatin scaffold protein STRN4 through interaction with the phosphatase PP2A

    Article • Journal of Biological Chemistry, April 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Kwok-On Lai

  15. The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines

    Article • Nature Communications, October 2016, Springer Science + Business Media

    Dr Kwok-On Lai

  16. Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca 2+ entry

    Article • Science Signaling, September 2016, American Association for the Advancement of Science

    Dr Kwok-On Lai

  17. Molecular Mechanisms of Dendritic Spine Development and Plasticity

    Article • Neural Plasticity, January 2016, Hindawi Publishing Corporation

    Dr Kwok-On Lai

  18. Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development

    Article • Journal of Neuroscience, November 2015, Society for Neuroscience

    Dr Kwok-On Lai

  19. Cyclin-dependent Kinase 5 (Cdk5)-dependent Phosphorylation of p70 Ribosomal S6 Kinase 1 (S6K) Is Required for Dendritic Spine Morphogenesis

    Article • Journal of Biological Chemistry, April 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Kwok-On Lai

  20. Cdk5: A Key Player at Neuronal Synapse with Diverse Functions

    Article • Mini-Reviews in Medicinal Chemistry, April 2015, Bentham Science Publishers

    Dr Kwok-On Lai

  21. Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, December 2013, Elsevier

    Dr Kwok-On Lai

  22. TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory

    Article • Nature Neuroscience, October 2012, Springer Science + Business Media

    Dr Kwok-On Lai

  23. APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

    Article • Nature Neuroscience, December 2010, Springer Science + Business Media

    Dr Kwok-On Lai

  24. Tyk2/STAT3 Signaling Mediates β-Amyloid-Induced Neuronal Cell Death: Implications in Alzheimer's Disease

    Article • Journal of Neuroscience, May 2010, Society for Neuroscience

    Dr Kwok-On Lai

  25. Recent advances in understanding the roles of Cdk5 in synaptic plasticity

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2009, Elsevier

    Dr Kwok-On Lai

  26. Synapse development and plasticity: roles of ephrin/Eph receptor signaling

    Article • Current Opinion in Neurobiology, June 2009, Elsevier

    Dr Kwok-On Lai

  27. Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons

    Article • Proceedings of the National Academy of Sciences, November 2008, Proceedings of the National Academy of Sciences

    Dr Kwok-On Lai

  28. Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism

    Article • Nature Neuroscience, December 2006, Nature

    Dr Mustafa Sahin, Dr Kwok-On Lai

  29. α-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner

    Article • Journal of Cell Biology, June 2005, Rockefeller University Press

    Dr Kwok-On Lai

  30. Identification of the Jak/Stat Proteins as Novel Downstream Targets of EphA4 Signaling in Muscle

    Article • Journal of Biological Chemistry, April 2004, Elsevier

    Dr Kwok-On Lai

  31. Ephrin-B1 Reverse Signaling Activates JNK through a Novel Mechanism That Is Independent of Tyrosine Phosphorylation

    Article • Journal of Biological Chemistry, July 2003, Elsevier

    Dr Kwok-On Lai

  32. Central synapse and neuromuscular junction: same players, different roles

    Article • Trends in Genetics, July 2003, Elsevier

    Dr Kwok-On Lai

  33. Postsynaptic signaling of new players at the neuromuscular junction

    Article • Journal of Neurocytology, June 2003, Springer Science + Business Media

    Dr Kwok-On Lai

  34. Expression of Eph Receptors in Skeletal Muscle and Their Localization at the Neuromuscular Junction

    Article • Molecular and Cellular Neuroscience, June 2001, Elsevier

    Dr Kwok-On Lai

  35. Cloning and Characterization of Muscle-Specific Kinase in Chicken

    Article • Molecular and Cellular Neuroscience, November 2000, Elsevier

    Dr Kwok-On Lai

  36. Identification and characterization of splice variants of ephrin‐A3 and ephrin‐A5

    Article • FEBS Letters, September 1999, Wiley

    Dr Kwok-On Lai

  37. Induction of NG108-15 cells differrentiation by human bone marrow stromal cells

    Article • Neuroreport, May 1998, Wolters Kluwer Health

    Dr Kwok-On Lai

  38. Cloning and Expression of a Novel Neurotrophin, NT-7, from Carp

    Article • Molecular and Cellular Neuroscience, May 1998, Elsevier

    Dr Kwok-On Lai

  39. Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron–muscle co-cultures

    Article • Neuroreport, December 1997, Wolters Kluwer Health

    Dr Kwok-On Lai

  40. Structural determinants of Trk receptor specificities using BNDF-based neurotrophin chimeras

    Article • Journal of Neuroscience Research, December 1996, Wiley

    Dr Kwok-On Lai