All Stories

  1. PC945, a Novel Inhaled Antifungal Agent, for the Treatment of Respiratory Fungal Infections

    Article • Journal of Fungi, December 2020, MDPI AG

    Dr Kazuhiro Ito

  2. The role of antifungals in the management of patients with severe asthma

    Article • Clinical and Translational Allergy, November 2020, Springer Science + Business Media

    Dr Kazuhiro Ito

  3. OUP accepted manuscript

    Article • The Journal of Infectious Diseases, January 2020, Oxford University Press (OUP)

    Dr Kazuhiro Ito

  4. Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus

    Article • Journal of Antimicrobial Chemotherapy, July 2019, Oxford University Press (OUP)

    Dr Yasuo Kizawa, Dr Kazuhiro Ito

  5. In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris

    Article • Journal of Antimicrobial Chemotherapy, July 2019, Oxford University Press (OUP)

    Dr Kazuhiro Ito

  6. Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection

    Article • Scientific Reports, July 2019, Springer Science + Business Media

    Dr Kazuhiro Ito, Dr Yasuo Kizawa

  7. 1335. Safety and Pharmacokinetic Profile of PC786, a Novel Inhibitor of Respiratory Syncytial Virus L-protein Polymerase, in a Single and Multiple-Ascending Dose Study in Healthy Volunteer and Mild Asthmatics

    Article • Open Forum Infectious Diseases, November 2018, Oxford University Press (OUP)

    Dr Kazuhiro Ito

  8. Anti-viral efefcts of a Novel RSV polymerase inhibitor, PC786, on primary airrway epithelial cells.

    Article • Bone Marrow Transplantation, May 2018, Wiley

    Dr Kazuhiro Ito

  9. Current approaches to the discovery of novel inhaled medicines

    Article • Drug Discovery Today, May 2018, Elsevier

    Dr Kazuhiro Ito

  10. In VitroandIn VivoEfficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, onAspergillus fumigatusInfection

    Article • Antimicrobial Agents and Chemotherapy, February 2018, ASM Journals

    Professor Matthew C Fisher, Dr Yasuo Kizawa, Dr Kazuhiro Ito

  11. Reply to Rojas, “The Imperative Authentication of Cell Lines”

    Article • Antimicrobial Agents and Chemotherapy, October 2017, ASM Journals

    Dr Kazuhiro Ito

  12. Effects of intranasally dosed posaconazole on fungal load and biomarkers in Aspergillus fumigatus infected immunocompromised mice

    Article • Mycoses, July 2017, Wiley

    Dr Kazuhiro Ito, Dr Yasuo Kizawa

  13. A novel inhaled RSV polymerase inhibitor, PC786, on RSV infection

    Article • Antimicrobial Agents and Chemotherapy, June 2017, ASM Journals

    Dr Kazuhiro Ito

  14. In Vivo Biomarker Analysis of the Effects of Intranasally Dosed PC945, a Novel Antifungal Triazole, on Aspergillus fumigatus Infection in Immunocompromised Mice

    Article • Antimicrobial Agents and Chemotherapy, June 2017, ASM Journals

    Dr Kazuhiro Ito, Dr Yasuo Kizawa

  15. Nasosorption as a Minimally Invasive Sampling Procedure: Mucosal Viral Load and Inflammation in Primary RSV Bronchiolitis

    Article • The Journal of Infectious Diseases, March 2017, Oxford University Press (OUP)

    Dr Kazuhiro Ito

  16. In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection

    Article • Antimicrobial Agents and Chemotherapy, February 2017, ASM Journals

    Dr Kazuhiro Ito, Dr Yasuo Kizawa

  17. NDP52 inhibition rescues cigarette smoke mediated impairment of autophagy in macrophages

    Article • September 2016, European Respiratory Society (ERS)

    Dr Kazuhiro Ito

  18. LATE-BREAKING ABSTRACT: Effects of a single treatment with PC786, a novel inhibitor of respiratory syncytial virus replication, on viral load and biomarkers in fully differentiated human bronchial epithelial cells

    Article • September 2016, European Respiratory Society (ERS)

    Dr Kazuhiro Ito

  19. Recurrent cigarette smoke exposure impairs SIRT1 shuttling in bronchial epithelial cells

    Article • September 2016, European Respiratory Society (ERS)

    Dr Kazuhiro Ito

  20. Faculty of 1000 evaluation for Activated mouse eosinophils protect against lethal respiratory virus infection.

    Article • June 2016, Faculty of 1000, Ltd.

    Dr Kazuhiro Ito

  21. Inflammation to Pulmonary Diseases

    Article • Mediators of Inflammation, January 2016, Hindawi Publishing Corporation

    Dr Kazuhiro Ito

  22. In Vivo Biomarker Analysis of Intranasally Dosed PC945, a Novel Antifungal Agent, in Aspergillus Fumigatus Infection in Immunocompromised Mice

    Article • Open Forum Infectious Diseases, January 2016, Oxford University Press (OUP)

    Dr Kazuhiro Ito, Dr Yasuo Kizawa

  23. Anti-Viral Activities of PC786, a Novel Inhibitor of Respiratory Syncytial Virus L-Protein Polymerase

    Article • Open Forum Infectious Diseases, January 2016, Oxford University Press (OUP)

    Dr Kazuhiro Ito

  24. STOP accelerating lung aging for the treatment of COPD

    Article • Experimental Gerontology, November 2014, Elsevier

    Dr Kazuhiro Ito

  25. Comparison of Symbicort® versus Pulmicort® on steroid pharmacodynamic markers in asthma patients

    Article • Respiratory Medicine, December 2011, Elsevier

    Dr Kazuhiro Ito

  26. 60 Effects of RV568, a novel narrow spectrum kinase inhibitor, on pro-inflammatory cytokine production in epithelial cells isolated from patients with cystic fibrosis

    Article • Journal of Cystic Fibrosis, June 2011, Elsevier

    Dr Kazuhiro Ito

  27. 89 Superior effects of RV568, a narrow spectrum kinase inhibitor, on RSV infection in primary bronchial epithelial cells obtained from patients with cystic fibrosis

    Article • Journal of Cystic Fibrosis, June 2011, Elsevier

    Dr Kazuhiro Ito

  28. Effects Of RV568, A Narrow Spectrum Kinase Inhibitor, On Human Rhinovirus Replication And Cytokine Production

    Article • May 2011, American Thoracic Society

    Dr Kazuhiro Ito

  29. C13 Corticosteroids

    Article • January 2011, Springer Science + Business Media

    Dr Kazuhiro Ito

  30. Faculty of 1000 evaluation for Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase.

    Article • November 2010, Faculty of 1000, Ltd.

    Dr Kazuhiro Ito

  31. Fluticasone Furoate, A Novel Enhanced-affinity Inhaled Corticosteroid (ICS), Has Superior Anti-inflammatory Effects Compared To Fluticasone Propionate Under Conditions Of Oxidative Stress

    Article • May 2010, American Thoracic Society

    Dr Kazuhiro Ito

  32. Targeting Th2 Cells in Asthmatic Airways

    Article • January 2010, Springer Science + Business Media

    Dr Kazuhiro Ito

  33. Peroxynitrite Elevation in Exhaled Breath Condensate of COPD and Its Inhibition by Fudosteine

    Article • CHEST Journal, June 2009, Elsevier

    Dr Kazuhiro Ito

  34. Nitric Oxide

    Article • January 2009, Elsevier

    Dr Kazuhiro Ito

  35. COPD as a Disease of Accelerated Lung Aging

    Article • CHEST Journal, January 2009, Elsevier

    Dr Kazuhiro Ito

  36. Differential Flow Analysis of Exhaled Nitric Oxide in Patients With Asthma of Differing Severity

    Article • CHEST Journal, May 2007, Elsevier

    Dr Kazuhiro Ito

  37. New Insights into the Molecular Mechanisms of Corticosteroids Actions

    Article • Current Drug Targets, June 2006, Bentham Science Publishers

    Dr Kazuhiro Ito

  38. Glucocorticoid Receptor Nuclear Translocation in Airway Cells after Inhaled Combination Therapy

    Article • American Review of Respiratory Disease, September 2005, American Thoracic Society

    Dr Kazuhiro Ito

  39. Histone Acetylation and Histone Deacetylation

    Article • Molecular Biotechnology, January 2002, Springer Science + Business Media

    Dr Kazuhiro Ito

  40. Histone Acetylation and Histone Deacetylation

    Article • Springer Science + Business Media

    Dr Kazuhiro Ito

  41. Corticosteroids

    Article • Springer Science + Business Media

    Dr Kazuhiro Ito

  42. Steroid-Sparing Strategies: Other Combinations

    Article • Wiley

    Dr Kazuhiro Ito