All Stories

  1. Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals—What We Know So Far

    Article • Materials, April 2023, MDPI AG

    Prof. Dr. Karsten Grote

  2. Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc)

    Article • Frontiers in Pharmacology, June 2022, Frontiers

    Prof. Dr. Karsten Grote

  3. Extracellular Ribosomal RNA Acts Synergistically with Toll-like Receptor 2 Agonists to Promote Inflammation

    Article • Cells, April 2022, MDPI AG

    Prof. Dr. Karsten Grote

  4. Monocyte subpopulation profiling indicates CDK6-derived cell differentiation and identifies subpopulation-specific miRNA expression sets in acute and stable coronary artery disease

    Article • Scientific Reports, April 2022, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  5. Polystyrene microplastic particles induce endothelial activation

    Article • PLoS ONE, November 2021, PLOS

    Prof. Dr. Karsten Grote

  6. Anti-Inflammatory Effects of C1q/Tumor Necrosis Factor-Related Protein 3 (CTRP3) in Endothelial Cells

    Article • Cells, August 2021, MDPI AG

    Prof. Dr. Karsten Grote

  7. Deficiency of Nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 reduces atherosclerosis

    Article • Basic Research in Cardiology, June 2020, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  8. Identification of microRNAs involved in NOD-dependent induction of pro-inflammatory genes in pulmonary endothelial cells

    Article • PLoS ONE, April 2020, PLOS

    Prof. Dr. Karsten Grote

  9. The Lipopeptide MALP-2 Promotes Collateral Growth

    Article • Cells, April 2020, MDPI AG

    Prof. Dr. Karsten Grote

  10. Therapeutisches Kollateralwachstum

    Article • Gefässchirurgie, October 2019, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  11. Heparan Sulfate–Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair

    Article • Circulation Research, October 2019, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  12. Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans

    Article • Atherosclerosis, July 2019, Elsevier

    Prof. Dr. Karsten Grote

  13. Toll-like-Rezeptor 2/6 Signaling bei vaskulärer Regeneration und Adaptation

    Article • Gefässchirurgie, June 2019, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  14. Suppressor of Cytokine Signaling 1 is Involved in Gene Regulation Which Controls the Survival of Ly6Clow Monocytes in Mice

    Article • Cellular Physiology and Biochemistry, February 2019, Cell Physiol Biochem Press GmbH and Co KG

    Prof. Dr. Karsten Grote

  15. Variety matters: Diverse functions of monocyte subtypes in vascular inflammation and atherogenesis

    Article • Vascular Pharmacology, February 2019, Elsevier

    Prof. Dr. Karsten Grote

  16. Anti-tumor necrosis factor-α therapy increases plaque burden in a mouse model of experimental atherosclerosis

    Article • Atherosclerosis, October 2018, Elsevier

    Prof. Dr. Karsten Grote

  17. NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells

    Article • The FASEB Journal, March 2017, Federation of American Societies For Experimental Biology (FASEB)

    Prof. Dr. Karsten Grote

  18. Toll-Like Receptors in Angiogenesis

    Article • January 2017, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  19. Differential Expression of MicroRNAs in Endarterectomy Specimens Taken from Patients with Asymptomatic and Symptomatic Carotid Plaques

    Article • PLoS ONE, September 2016, PLOS

    Prof. Dr. Karsten Grote

  20. Targeting Tumor Necrosis Factor-α with Adalimumab: Effects on Endothelial Activation and Monocyte Adhesion

    Article • PLoS ONE, July 2016, PLOS

    Prof. Dr. Karsten Grote

  21. Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease

    Article • PLoS ONE, September 2015, PLOS

    Prof. Dr. Karsten Grote

  22. Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis

    Article • Basic Research in Cardiology, October 2014, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  23. Toll-like receptor 2/6-dependent stimulation of mesenchymal stem cells promotes angiogenesis by paracrine factors

    Article • September 2013, ECM Research Journal

    Prof. Dr. Karsten Grote

  24. Toll-Like Receptor 2/6 Agonist Macrophage-Activating Lipopeptide-2 Promotes Reendothelialization and Inhibits Neointima Formation After Vascular Injury

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2013, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  25. Experimental Gingivitis Induces Systemic Inflammatory Markers in Young Healthy Individuals: A Single-Subject Interventional Study

    Article • PLoS ONE, February 2013, PLOS

    Prof. Dr. Karsten Grote

  26. Toll-Like Receptor-Linked Signal Transduction in Angiogenesis

    Article • January 2013, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  27. Role of Suppressor of Cytokine Signaling-1 In Murine Atherosclerosis

    Article • PLoS ONE, December 2012, PLOS

    Prof. Dr. Karsten Grote

  28. Interleukin-1 Assembles a Proangiogenic Signaling Module Consisting of Caveolin-1, Tumor Necrosis Factor Receptor–Associated Factor 6, p38–Mitogen-Activated Protein Kinase (MAPK), and MAPK-Activated Protein Kinase 2 in Endothelial Cells

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2012, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  29. Transsignaling of Interleukin-6 Crucially Contributes to Atherosclerosis in Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2012, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  30. Gp130-Dependent Release of Acute Phase Proteins Is Linked to the Activation of Innate Immune Signaling Pathways

    Article • PLoS ONE, May 2011, PLOS

    Professor Werner Muller, Prof. Dr. Karsten Grote

  31. Toll-Like Receptors in Angiogenesis

    Article • The Scientific World JOURNAL, January 2011, Hindawi Publishing Corporation

    Prof. Dr. Karsten Grote

  32. Chemokine Receptor 7 Knockout Attenuates Atherosclerotic Plaque Development

    Article • Circulation, October 2010, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  33. ADAMTS13--marker of contractile phenotype of arterial smooth muscle cells lost in benign nephrosclerosis

    Article • Nephrology Dialysis Transplantation, October 2010, Oxford University Press (OUP)

    Prof. Dr. Karsten Grote

  34. Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration

    Article • Blood, March 2010, American Society of Hematology

    Prof. Dr. Karsten Grote

  35. Mechanical Stress Modulates SOCS-1 Expression in Human Vascular Smooth Muscle Cells

    Article • Journal of Vascular Research, January 2010, Karger Publishers

    Prof. Dr. Karsten Grote

  36. Actin-Binding Rho Activating Protein (Abra) Is Essential for Fluid Shear Stress-Induced Arteriogenesis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, December 2009, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  37. Hepatocyte gp130 Deficiency Reduces Vascular Remodeling After Carotid Artery Ligation

    Article • Hypertension, November 2009, Wolters Kluwer Health

    Professor Werner Muller, Prof. Dr. Karsten Grote

  38. Ex vivoexpanded haematopoietic progenitor cells improve dermal wound healing by paracrine mechanisms

    Article • Experimental Dermatology, May 2009, Wiley

    Prof. Dr. Karsten Grote

  39. Immunostimulation with Macrophage-Activating Lipopeptide-2 Increased Survival in Murine Pneumonia

    Article • American Journal of Respiratory Cell and Molecular Biology, April 2009, American Thoracic Society

    Prof. Dr. Karsten Grote

  40. How much is too much? Interleukin-6 and its signalling in atherosclerosis

    Article • Thrombosis and Haemostasis, January 2009, Thieme Publishing Group

    Prof. Dr. Karsten Grote

  41. Ex vivo expanded hematopoietic progenitor cells improve cardiac function after myocardial infarction: Role of β-catenin transduction and cell dose

    Article • Journal of Molecular and Cellular Cardiology, September 2008, Elsevier

    Prof. Dr. Karsten Grote

  42. Postnatal Life Events Affect the Severity of Asthmatic Airway Inflammation in the Adult Rat

    Article • The Journal of Immunology, March 2008, The American Association of Immunologists

    Prof. Dr. Karsten Grote

  43. Renovascular hypertension by two-kidney one-clip enhances endothelial progenitor cell mobilization in a p47phox-dependent manner

    Article • Journal of Hypertension, February 2008, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  44. Angiotensin II type 1-receptor antagonism prevents type IIA secretory phospholipase A2-dependent lipid peroxidation

    Article • Atherosclerosis, September 2007, Elsevier

    Prof. Dr. Karsten Grote

  45. The angiogenic factor CCN1 promotes adhesion and migration of circulating CD34+ progenitor cells: potential role in angiogenesis and endothelial regeneration

    Article • Blood, August 2007, American Society of Hematology

    Prof. Dr. Karsten Grote

  46. Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

    Article • The Journal of Experimental Medicine, July 2007, Rockefeller University Press

    Professor Werner Muller, Prof. Dr. Karsten Grote

  47. Critical Role of the NAD(P)H Oxidase Subunit p47 phox for Left Ventricular Remodeling/Dysfunction and Survival After Myocardial Infarction

    Article • Circulation Research, March 2007, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  48. Local pulmonary immune stimulation by the Toll-like receptor 2 and 6 ligand MALP-2 in rats is age dependent

    Article • Immunology Letters, February 2007, Elsevier

    Prof. Dr. Karsten Grote

  49. Critical role for p47phox in renin–angiotensin system activation and blood pressure regulation

    Article • Cardiovascular Research, August 2006, European Society of Cardiology

    Prof. Dr. Karsten Grote

  50. JANUS under stress—Role of JAK/STAT signaling pathway in vascular diseases

    Article • Vascular Pharmacology, November 2005, Elsevier

    Prof. Dr. Karsten Grote

  51. Combined effects of HMG-CoA-reductase inhibition and renin–angiotensin system blockade on experimental atherosclerosis

    Article • Atherosclerosis, September 2005, Elsevier

    Prof. Dr. Karsten Grote

  52. Angiotensin II induces MMP-2 in a p47phox-dependent manner

    Article • Biochemical and Biophysical Research Communications, March 2005, Elsevier

    Prof. Dr. Karsten Grote

  53. Impact of Interleukin-6 on Plaque Development and Morphology in Experimental Atherosclerosis

    Article • Circulation, November 2004, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  54. Stretch-inducible Expression of the Angiogenic Factor CCN1 in Vascular Smooth Muscle Cells Is Mediated by Egr-1

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof. Dr. Karsten Grote

  55. Regulation of Proangiogenic Factor CCN1 in Cardiac Muscle

    Article • Circulation, May 2004, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  56. Renin-angiotensin system and atherosclerosis

    Article • Nephrology Dialysis Transplantation, March 2004, Oxford University Press (OUP)

    Prof. Dr. Karsten Grote

  57. Mechanical Stretch Enhances mRNA Expression and Proenzyme Release of Matrix Metalloproteinase-2 (MMP-2) via NAD(P)H Oxidase–Derived Reactive Oxygen Species

    Article • Circulation Research, June 2003, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  58. Intratracheal Macrophage-Activating Lipopeptide-2 Reduces Metastasis in the Rat Lung

    Article • American Journal of Respiratory Cell and Molecular Biology, March 2003, American Thoracic Society

    Prof. Dr. Karsten Grote

  59. Cutting Edge: Preferentially the R-Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway

    Article • The Journal of Immunology, January 2000, The American Association of Immunologists

    Prof. Dr. Karsten Grote

  60. The Nicotiana tabacum plasma membrane aquaporin NtAQP1 is mercury-insensitive and permeable for glycerol

    Article • The Plant Journal, June 1999, Wiley

    Prof. Dr. Karsten Grote

  61. Coulter counter cell size determination of protoplasts fromArabidopsis thaliana PIP1b aquaporin antisense lines under iso- and hypo-osmotic conditions

    Article • PROTOPLASMA, March 1999, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  62. RNA levels of plasma membrane aquaporins inArabidopsis thaliana

    Article • PROTOPLASMA, September 1998, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  63. Significance of plasmalemma aquaporins for water-transport in Arabidopsis thaliana

    Article • The Plant Journal, April 1998, Wiley

    Prof. Dr. Karsten Grote