All Stories

  1. Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2

    Article • International Journal of Molecular Sciences, April 2024, MDPI AG

    Prof. Dr. Karsten Grote

  2. Cathelicidin Antimicrobial Peptide Levels in Atherosclerosis and Myocardial Infarction in Mice and Human

    Article • International Journal of Molecular Sciences, March 2024, MDPI AG

    Prof. Dr. Karsten Grote

  3. Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals—What We Know So Far

    Article • Materials, April 2023, MDPI AG

    Prof. Dr. Karsten Grote

  4. Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc)

    Article • Frontiers in Pharmacology, June 2022, Frontiers

    Prof. Dr. Karsten Grote

  5. Extracellular Ribosomal RNA Acts Synergistically with Toll-like Receptor 2 Agonists to Promote Inflammation

    Article • Cells, April 2022, MDPI AG

    Prof. Dr. Karsten Grote

  6. Monocyte subpopulation profiling indicates CDK6-derived cell differentiation and identifies subpopulation-specific miRNA expression sets in acute and stable coronary artery disease

    Article • Scientific Reports, April 2022, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  7. Polystyrene microplastic particles induce endothelial activation

    Article • PLOS One, November 2021, PLOS

    Prof. Dr. Karsten Grote

  8. Anti-Inflammatory Effects of C1q/Tumor Necrosis Factor-Related Protein 3 (CTRP3) in Endothelial Cells

    Article • Cells, August 2021, MDPI AG

    Prof. Dr. Karsten Grote

  9. Deficiency of Nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 reduces atherosclerosis

    Article • Basic Research in Cardiology, June 2020, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  10. Identification of microRNAs involved in NOD-dependent induction of pro-inflammatory genes in pulmonary endothelial cells

    Article • PLOS One, April 2020, PLOS

    Prof. Dr. Karsten Grote

  11. The Lipopeptide MALP-2 Promotes Collateral Growth

    Article • Cells, April 2020, MDPI AG

    Prof. Dr. Karsten Grote

  12. Therapeutisches Kollateralwachstum

    Article • Gefässchirurgie, October 2019, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  13. Heparan Sulfate–Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair

    Article • Circulation Research, October 2019, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  14. Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans

    Article • Atherosclerosis, July 2019, Elsevier

    Prof. Dr. Karsten Grote

  15. Toll-like-Rezeptor 2/6 Signaling bei vaskulärer Regeneration und Adaptation

    Article • Gefässchirurgie, June 2019, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  16. Suppressor of Cytokine Signaling 1 is Involved in Gene Regulation Which Controls the Survival of Ly6Clow Monocytes in Mice

    Article • Cellular Physiology and Biochemistry, February 2019, Cell Physiol Biochem Press GmbH and Co KG

    Prof. Dr. Karsten Grote

  17. Variety matters: Diverse functions of monocyte subtypes in vascular inflammation and atherogenesis

    Article • Vascular Pharmacology, February 2019, Elsevier

    Prof. Dr. Karsten Grote

  18. Anti-tumor necrosis factor-α therapy increases plaque burden in a mouse model of experimental atherosclerosis

    Article • Atherosclerosis, October 2018, Elsevier

    Prof. Dr. Karsten Grote

  19. NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells

    Article • The FASEB Journal, March 2017, Federation of American Societies For Experimental Biology (FASEB)

    Prof. Dr. Karsten Grote

  20. Toll-Like Receptors in Angiogenesis

    Article • January 2017, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  21. Differential Expression of MicroRNAs in Endarterectomy Specimens Taken from Patients with Asymptomatic and Symptomatic Carotid Plaques

    Article • PLOS One, September 2016, PLOS

    Prof. Dr. Karsten Grote

  22. Targeting Tumor Necrosis Factor-α with Adalimumab: Effects on Endothelial Activation and Monocyte Adhesion

    Article • PLOS One, July 2016, PLOS

    Prof. Dr. Karsten Grote

  23. Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease

    Article • PLOS One, September 2015, PLOS

    Prof. Dr. Karsten Grote

  24. Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis

    Article • Basic Research in Cardiology, October 2014, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  25. Toll-like receptor 2/6-dependent stimulation of mesenchymal stem cells promotes angiogenesis by paracrine factors

    Article • September 2013, ECM Research Journal

    Prof. Dr. Karsten Grote

  26. Toll-Like Receptor 2/6 Agonist Macrophage-Activating Lipopeptide-2 Promotes Reendothelialization and Inhibits Neointima Formation After Vascular Injury

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2013, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  27. Experimental Gingivitis Induces Systemic Inflammatory Markers in Young Healthy Individuals: A Single-Subject Interventional Study

    Article • PLOS One, February 2013, PLOS

    Prof. Dr. Karsten Grote

  28. Toll-Like Receptor-Linked Signal Transduction in Angiogenesis

    Article • January 2013, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  29. Role of Suppressor of Cytokine Signaling-1 In Murine Atherosclerosis

    Article • PLOS One, December 2012, PLOS

    Prof. Dr. Karsten Grote

  30. Interleukin-1 Assembles a Proangiogenic Signaling Module Consisting of Caveolin-1, Tumor Necrosis Factor Receptor–Associated Factor 6, p38–Mitogen-Activated Protein Kinase (MAPK), and MAPK-Activated Protein Kinase 2 in Endothelial Cells

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2012, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  31. Transsignaling of Interleukin-6 Crucially Contributes to Atherosclerosis in Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2012, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  32. Gp130-Dependent Release of Acute Phase Proteins Is Linked to the Activation of Innate Immune Signaling Pathways

    Article • PLOS One, May 2011, PLOS

    Professor Werner Muller, Prof. Dr. Karsten Grote

  33. Toll-Like Receptors in Angiogenesis

    Article • The Scientific World JOURNAL, January 2011, Hindawi Publishing Corporation

    Prof. Dr. Karsten Grote

  34. Chemokine Receptor 7 Knockout Attenuates Atherosclerotic Plaque Development

    Article • Circulation, October 2010, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  35. ADAMTS13--marker of contractile phenotype of arterial smooth muscle cells lost in benign nephrosclerosis

    Article • Nephrology Dialysis Transplantation, October 2010, Oxford University Press (OUP)

    Prof. Dr. Karsten Grote

  36. Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration

    Article • Blood, March 2010, American Society of Hematology

    Prof. Dr. Karsten Grote

  37. Mechanical Stress Modulates SOCS-1 Expression in Human Vascular Smooth Muscle Cells

    Article • Journal of Vascular Research, January 2010, Karger Publishers

    Prof. Dr. Karsten Grote

  38. Actin-Binding Rho Activating Protein (Abra) Is Essential for Fluid Shear Stress-Induced Arteriogenesis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, December 2009, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  39. Hepatocyte gp130 Deficiency Reduces Vascular Remodeling After Carotid Artery Ligation

    Article • Hypertension, November 2009, Wolters Kluwer Health

    Professor Werner Muller, Prof. Dr. Karsten Grote

  40. Ex vivoexpanded haematopoietic progenitor cells improve dermal wound healing by paracrine mechanisms

    Article • Experimental Dermatology, May 2009, Wiley

    Prof. Dr. Karsten Grote

  41. Immunostimulation with Macrophage-Activating Lipopeptide-2 Increased Survival in Murine Pneumonia

    Article • American Journal of Respiratory Cell and Molecular Biology, April 2009, American Thoracic Society

    Prof. Dr. Karsten Grote

  42. How much is too much? Interleukin-6 and its signalling in atherosclerosis

    Article • Thrombosis and Haemostasis, January 2009, Thieme Publishing Group

    Prof. Dr. Karsten Grote

  43. Ex vivo expanded hematopoietic progenitor cells improve cardiac function after myocardial infarction: Role of β-catenin transduction and cell dose

    Article • Journal of Molecular and Cellular Cardiology, September 2008, Elsevier

    Prof. Dr. Karsten Grote

  44. Postnatal Life Events Affect the Severity of Asthmatic Airway Inflammation in the Adult Rat

    Article • The Journal of Immunology, March 2008, The American Association of Immunologists

    Prof. Dr. Karsten Grote

  45. Renovascular hypertension by two-kidney one-clip enhances endothelial progenitor cell mobilization in a p47phox-dependent manner

    Article • Journal of Hypertension, February 2008, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  46. Angiotensin II type 1-receptor antagonism prevents type IIA secretory phospholipase A2-dependent lipid peroxidation

    Article • Atherosclerosis, September 2007, Elsevier

    Prof. Dr. Karsten Grote

  47. The angiogenic factor CCN1 promotes adhesion and migration of circulating CD34+ progenitor cells: potential role in angiogenesis and endothelial regeneration

    Article • Blood, August 2007, American Society of Hematology

    Prof. Dr. Karsten Grote

  48. Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

    Article • Journal of Experimental Medicine, July 2007, Rockefeller University Press

    Professor Werner Muller, Prof. Dr. Karsten Grote

  49. Critical Role of the NAD(P)H Oxidase Subunit p47 phox for Left Ventricular Remodeling/Dysfunction and Survival After Myocardial Infarction

    Article • Circulation Research, March 2007, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  50. Local pulmonary immune stimulation by the Toll-like receptor 2 and 6 ligand MALP-2 in rats is age dependent

    Article • Immunology Letters, February 2007, Elsevier

    Prof. Dr. Karsten Grote

  51. Critical role for p47phox in renin–angiotensin system activation and blood pressure regulation

    Article • Cardiovascular Research, August 2006, European Society of Cardiology

    Prof. Dr. Karsten Grote

  52. JANUS under stress—Role of JAK/STAT signaling pathway in vascular diseases

    Article • Vascular Pharmacology, November 2005, Elsevier

    Prof. Dr. Karsten Grote

  53. Combined effects of HMG-CoA-reductase inhibition and renin–angiotensin system blockade on experimental atherosclerosis

    Article • Atherosclerosis, September 2005, Elsevier

    Prof. Dr. Karsten Grote

  54. Angiotensin II induces MMP-2 in a p47phox-dependent manner

    Article • Biochemical and Biophysical Research Communications, March 2005, Elsevier

    Prof. Dr. Karsten Grote

  55. Impact of Interleukin-6 on Plaque Development and Morphology in Experimental Atherosclerosis

    Article • Circulation, November 2004, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  56. Stretch-inducible Expression of the Angiogenic Factor CCN1 in Vascular Smooth Muscle Cells Is Mediated by Egr-1

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof. Dr. Karsten Grote

  57. Regulation of Proangiogenic Factor CCN1 in Cardiac Muscle

    Article • Circulation, May 2004, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  58. Renin-angiotensin system and atherosclerosis

    Article • Nephrology Dialysis Transplantation, March 2004, Oxford University Press (OUP)

    Prof. Dr. Karsten Grote

  59. Mechanical Stretch Enhances mRNA Expression and Proenzyme Release of Matrix Metalloproteinase-2 (MMP-2) via NAD(P)H Oxidase–Derived Reactive Oxygen Species

    Article • Circulation Research, June 2003, Wolters Kluwer Health

    Prof. Dr. Karsten Grote

  60. Intratracheal Macrophage-Activating Lipopeptide-2 Reduces Metastasis in the Rat Lung

    Article • American Journal of Respiratory Cell and Molecular Biology, March 2003, American Thoracic Society

    Prof. Dr. Karsten Grote

  61. Cutting Edge: Preferentially the R-Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway

    Article • The Journal of Immunology, January 2000, The American Association of Immunologists

    Prof. Dr. Karsten Grote, Osamu Takeuchi

  62. The Nicotiana tabacum plasma membrane aquaporin NtAQP1 is mercury-insensitive and permeable for glycerol

    Article • The Plant Journal, June 1999, Wiley

    Prof. Dr. Karsten Grote

  63. Coulter counter cell size determination of protoplasts fromArabidopsis thaliana PIP1b aquaporin antisense lines under iso- and hypo-osmotic conditions

    Article • PROTOPLASMA, March 1999, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  64. RNA levels of plasma membrane aquaporins inArabidopsis thaliana

    Article • PROTOPLASMA, September 1998, Springer Science + Business Media

    Prof. Dr. Karsten Grote

  65. Significance of plasmalemma aquaporins for water-transport in Arabidopsis thaliana

    Article • The Plant Journal, April 1998, Wiley

    Prof. Dr. Karsten Grote