All Stories

  1. Experimental inoculation of CD11c+ B1 lymphocytes, CD68+ macrophages, or platelet-rich plasma from scrapie-infected sheep into susceptible sheep results in variable infectivity

    Article • Access Microbiology, July 2020, Society for General Microbiology

    Dr. Justin Greenlee

  2. Experimental Study Using Multiple Strains of Prion Disease in Cattle Reveals an Inverse Relationship between Incubation Time and Misfolded Prion Accumulation, Neuroinflammation, and Autophagy

    Article • American Journal Of Pathology, July 2020, Elsevier

    Dr. Justin Greenlee

  3. Bovine adapted transmissible mink encephalopathy is similar to L-BSE after passage through sheep with the VRQ/VRQ genotype but not VRQ/ARQ

    Article • June 2020, Research Square

    Dr. Justin Greenlee

  4. An Ex Vivo Brain Slice Culture Model of Chronic Wasting Disease: Implications for Disease Pathogenesis and Therapeutic Development

    Article • Scientific Reports, May 2020, Springer Science + Business Media

    Dr. Justin Greenlee

  5. Novel Strain of the Chronic Wasting Disease Agent Isolated From Experimentally Inoculated Elk With LL132 Prion Protein

    Article • Scientific Reports, February 2020, Springer Science + Business Media

    Dr. Justin Greenlee

  6. Role of donor genotype in RT-QuIC seeding activity of chronic wasting disease prions using human and bank vole substrates

    Article • PLoS ONE, January 2020, PLOS

    Dr. Justin Greenlee

  7. In Situ Temporospatial Characterization of the Glial Response to Prion Infection

    Article • Veterinary Pathology, July 2019, SAGE Publications

    Dr. Justin Greenlee

  8. Raccoons accumulate PrPSc after intracranial inoculation of the agents of chronic wasting disease or transmissible mink encephalopathy but not atypical scrapie

    Article • Journal of Veterinary Diagnostic Investigation, January 2019, SAGE Publications

    Dr. Justin Greenlee

  9. Sheep With the Homozygous Lysine-171 Prion Protein Genotype Are Resistant to Classical Scrapie After Experimental Oronasal Inoculation

    Article • Veterinary Pathology, December 2018, SAGE Publications

    Dr. Justin Greenlee

  10. Review: Update on Classical and Atypical Scrapie in Sheep and Goats

    Article • Veterinary Pathology, September 2018, SAGE Publications

    Dr. Justin Greenlee

  11. Pathologic and biochemical characterization of PrPSc from elk with PRNP polymorphisms at codon 132 after experimental infection with the chronic wasting disease agent

    Article • BMC Veterinary Research, March 2018, Springer Science + Business Media

    Dr. Justin Greenlee

  12. Real-Time Quaking-Induced Conversion Detection of Bovine Spongiform Encephalopathy Prions in a Subclinical Steer

    Article • Frontiers in Veterinary Science, January 2018, Frontiers

    Dr. Justin Greenlee

  13. Effects of a naturally occurring amino acid substitution in bovine PrP: a model for inherited prion disease in a natural host species

    Article • BMC Research Notes, December 2017, Springer Science + Business Media

    Dr. Justin Greenlee

  14. Experimental Transmission of the Chronic Wasting Disease Agent to Swine after Oral or Intracranial Inoculation

    Article • Journal of Virology, July 2017, ASM Journals

    Dr. Justin Greenlee

  15. Lasting Retinal Injury in a Mouse Model of Blast-Induced Trauma

    Article • American Journal Of Pathology, July 2017, Elsevier

    Dr. Justin Greenlee, Gary Zenitsky

  16. Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Discovery in Protein Misfolding Diseases

    Article • Scientific Reports, February 2017, Springer Science + Business Media

    Dr. Justin Greenlee

  17. Use of bovine recombinant prion protein and real-time quaking-induced conversion to detect cattle transmissible mink encephalopathy prions and discriminate classical and atypical L- and H-Type bovine spongiform encephalopathy

    Article • PLoS ONE, February 2017, PLOS

    Dr. Justin Greenlee

  18. Horizontal Transmission of Chronic Wasting Disease in Reindeer

    Article • Emerging Infectious Diseases, December 2016, Centers for Disease Control and Prevention (CDC)

    Dr. Justin Greenlee

  19. A Comparison of Classical and H-Type Bovine Spongiform Encephalopathy Associated with E211K Prion Protein Polymorphism in Wild-Type and EK211 Cattle Following Intracranial Inoculation

    Article • Frontiers in Veterinary Science, September 2016, Frontiers

    Dr. Justin Greenlee

  20. Temporal Resolution of Misfolded Prion Protein Transport, Accumulation, Glial Activation, and Neuronal Death in the Retinas of Mice Inoculated with Scrapie

    Article • American Journal Of Pathology, September 2016, Elsevier

    Dr. Justin Greenlee

  21. Genetic variation of the prion protein gene (PRNP) in alpaca (Vicugna pacos)

    Article • Gene Reports, September 2016, Elsevier

    Dr. Justin Greenlee

  22. Comparison of Two US Sheep Scrapie Isolates Supports Identification as Separate Strains

    Article • Veterinary Pathology, July 2016, SAGE Publications

    Dr. Justin Greenlee

  23. Limited amplification of chronic wasting disease prions in the peripheral tissues of intracerebrally inoculated cattle

    Article • Journal of General Virology, July 2016, Society for General Microbiology

    Dr. Justin Greenlee

  24. Oral inoculation of neonatal Suffolk sheep with the agent of classical scrapie results in PrPSc accumulation in sheep with the PRNP ARQ/ARQ but not the ARQ/ARR genotype

    Article • Research in Veterinary Science, April 2016, Elsevier

    Dr. Justin Greenlee

  25. Antemortem Detection of Chronic Wasting Disease Prions in Nasal Brush Collections and Rectal Biopsy Specimens from White-Tailed Deer by Real-Time Quaking-Induced Conversion

    Article • Journal of Clinical Microbiology, February 2016, ASM Journals

    Dr. Justin Greenlee

  26. Transmission of scrapie prions to primate after an extended silent incubation period

    Article • Scientific Reports, June 2015, Springer Science + Business Media

    Dr. Justin Greenlee

  27. The Transmissible Spongiform Encephalopathies of Livestock

    Article • ILAR Journal, May 2015, Oxford University Press (OUP)

    Dr. Justin Greenlee

  28. Changes in Retinal Function and Morphology Are Early Clinical Signs of Disease in Cattle with Bovine Spongiform Encephalopathy

    Article • PLoS ONE, March 2015, PLOS

    Dr. Justin Greenlee

  29. hTERT-immortalized ovine microglia propagate natural scrapie isolates

    Article • Virus Research, February 2015, Elsevier

    Dr David Arthur Schneider, Dr. Justin Greenlee

  30. Lack of Prion Accumulation in Lymphoid Tissues of PRNP ARQ/ARR Sheep Intracranially Inoculated with the Agent of Scrapie

    Article • PLoS ONE, September 2014, PLOS

    Dr. Justin Greenlee

  31. Detection of misfolded prion protein in retina samples of sheep and cattle by use of a commercially available enzyme immunoassay

    Article • American Journal of Veterinary Research, March 2014, American Veterinary Medical Association (AVMA)

    Dr. Justin Greenlee

  32. A Low-Molecular-Weight Ferroxidase Is Increased in the CSF of sCJD Cases: CSF Ferroxidase and Transferrin as Diagnostic Biomarkers for sCJD

    Article • Antioxidants & Redox Signaling, November 2013, Mary Ann Liebert Inc

    Professor George Perry, Dr. Justin Greenlee

  33. Evaluation of the Zoonotic Potential of Transmissible Mink Encephalopathy

    Article • Pathogens, July 2013, MDPI AG

    Dr. Justin Greenlee

  34. In Memoriam: Amir Hamir, DipAH, BVSc, MSc, PhD, Diplomate ECVP, MRCVS, 1944–2012

    Article • Veterinary Pathology, June 2013, SAGE Publications

    Dr. Justin Greenlee

  35. Correction: Clinical and Pathologic Features of H-Type Bovine Spongiform Encephalopathy Associated with E211K Prion Protein Polymorphism

    Article • PLoS ONE, January 2013, PLOS

    Dr. Justin Greenlee

  36. Evaluation of a combinatorial approach to prion inactivation using an oxidizing agent, SDS, and proteinase K

    Article • BMC Veterinary Research, January 2013, Springer Science + Business Media

    Dr. Justin Greenlee

  37. Exposure of RML scrapie agent to a sodium percarbonate-based product and sodium dodecyl sulfate renders PrPSc protease sensitive but does not eliminate infectivity

    Article • BMC Veterinary Research, January 2013, Springer Science + Business Media

    Dr. Justin Greenlee

  38. Stability properties of PrPSc from cattle with experimental transmissible spongiform encephalopathies: use of a rapid whole homogenate, protease-free assay

    Article • BMC Veterinary Research, January 2013, Springer Science + Business Media

    Dr. Justin Greenlee

  39. Detection of PrPSc in peripheral tissues of clinically affected cattle after oral challenge with bovine spongiform encephalopathy

    Article • Journal of General Virology, December 2012, Society for General Microbiology

    Dr. Justin Greenlee

  40. Susceptibility of cattle to the agent of chronic wasting disease from elk after intracranial inoculation

    Article • Journal of Veterinary Diagnostic Investigation, September 2012, SAGE Publications

    Dr. Justin Greenlee

  41. Relationships between PrPSc Stability and Incubation Time for United States Scrapie Isolates in a Natural Host System

    Article • PLoS ONE, August 2012, PLOS

    Dr. Justin Greenlee

  42. Clinical and Pathologic Features of H-Type Bovine Spongiform Encephalopathy Associated with E211K Prion Protein Polymorphism

    Article • PLoS ONE, June 2012, PLOS

    Dr. Justin Greenlee

  43. Acetone Precipitation of the Scrapie Agent Results in Successful Recovery of PrPScbut Decreased Infectivity

    Article • Journal of Agricultural and Food Chemistry, April 2012, American Chemical Society (ACS)

    Dr. Justin Greenlee

  44. Prolonged incubation time in sheep with prion protein containing lysine at position 171

    Article • Journal of Veterinary Diagnostic Investigation, April 2012, SAGE Publications

    Dr. Justin Greenlee

  45. Salivary prions in sheep and deer

    Article • Prion, January 2012, Taylor & Francis

    Dr. Justin Greenlee

  46. PrPSc detection in formalin-fixed paraffin-embedded tissue by ELISA

    Article • BMC Research Notes, October 2011, Springer Science + Business Media

    Dr. Justin Greenlee

  47. Evaluation of two sets of immunohistochemical and Western blot confirmatory methods in the detection of typical and atypical BSE cases

    Article • BMC Research Notes, September 2011, Springer Science + Business Media

    Dr. Justin Greenlee

  48. Experimental interspecies transmission studies of the transmissible spongiform encephalopathies to cattle

    Article • Journal of Veterinary Diagnostic Investigation, May 2011, SAGE Publications

    Dr. Justin Greenlee

  49. Bronchial Carcinoma in a Red-shouldered Hawk (Buteo lineatus)

    Article • Journal of Zoo and Wildlife Medicine, March 2011, American Association of Zoo Veterinarians

    Dr. Justin Greenlee

  50. Identification of an amino acid domain encoded by the capsid gene of porcine circovirus type 2 that modulates intracellular viral protein distribution during replication

    Article • Virus Research, January 2011, Elsevier

    Dr. Justin Greenlee

  51. White-tailed deer are susceptible to the agent of sheep scrapie by intracerebral inoculation

    Article • Veterinary Research, January 2011, Springer Science + Business Media

    Dr. Justin Greenlee

  52. Cartilaginous Metaplasia in the Sclera of Suffolk Sheep

    Article • Veterinary Pathology, September 2010, SAGE Publications

    Dr. Justin Greenlee

  53. Detection of the Abnormal Isoform of the Prion Protein Associated With Chronic Wasting Disease in the Optic Pathways of the Brain and Retina of Rocky Mountain Elk (Cervus elaphus nelsoni)

    Article • Veterinary Pathology, April 2010, SAGE Publications

    Dr. Justin Greenlee

  54. Altered electroretinogram b-wave in a Suffolk sheep experimentally infected with scrapie

    Article • Veterinary Record, August 2009, BMJ

    Dr. Justin Greenlee

  55. Characterization of a US Sheep Scrapie Isolate with Short Incubation Time

    Article • Veterinary Pathology, July 2009, SAGE Publications

    Dr. Justin Greenlee

  56. Retinal Function and Morphology Are Altered in Cattle Infected with the Prion Disease Transmissible Mink Encephalopathy

    Article • Veterinary Pathology, May 2009, SAGE Publications

    Dr. Justin Greenlee

  57. Experimental Oral Transmission of United States Origin Scrapie to Neonatal Sheep

    Article • Journal of Veterinary Diagnostic Investigation, January 2009, SAGE Publications

    Dr. Justin Greenlee

  58. Serial Passage of Sheep Scrapie Inoculum in Suffolk Sheep

    Article • Veterinary Pathology, January 2009, SAGE Publications

    Dr. Justin Greenlee

  59. Ablation of prion protein immunoreactivity by heating in saturated calcium hydroxide

    Article • BMC Research Notes, October 2008, Springer Science + Business Media

    Dr. Justin Greenlee

  60. Frequencies of polymorphisms associated with BSE resistance differ significantly between Bos taurus, Bos indicus, and composite cattle

    Article • BMC Veterinary Research, September 2008, Springer Science + Business Media

    Dr. Justin Greenlee

  61. Identification of a Heritable Polymorphism in Bovine PRNP Associated with Genetic Transmissible Spongiform Encephalopathy: Evidence of Heritable BSE

    Article • PLoS ONE, August 2008, PLOS

    Dr. Justin Greenlee

  62. Western Blot Detection of PrPSc in Archived Paraffin-Embedded Brainstem from Scrapie-Affected Sheep

    Article • Journal of Veterinary Diagnostic Investigation, July 2008, SAGE Publications

    Dr. Justin Greenlee

  63. Experimental Transmission of Chronic Wasting Disease (CWD) of Elk (Cervus elaphus nelsoni), White-tailed Deer (Odocoileus virginianus), and Mule Deer (Odocoileus hemionus hemionus) to White-tailed Deer by Intracerebral Route

    Article • Veterinary Pathology, May 2008, SAGE Publications

    Dr. Justin Greenlee

  64. Experimental Transmission of US Scrapie Agent by Nasal, Peritoneal, and Conjunctival Routes to Genetically Susceptible Sheep

    Article • Veterinary Pathology, January 2008, SAGE Publications

    Dr. Justin Greenlee

  65. Retinal Cell Types are Differentially Affected in Sheep with Scrapie

    Article • Journal of Comparative Pathology, January 2008, Elsevier

    Dr. Justin Greenlee

  66. Elk with a long incubation prion disease phenotype have a unique PrPd profile

    Article • Neuroreport, December 2007, Wolters Kluwer Health

    Dr. Justin Greenlee

  67. Abnormal Prion Accumulation Associated with Retinal Pathology in Experimentally Inoculated Scrapie-Affected Sheep

    Article • Veterinary Pathology, September 2006, SAGE Publications

    Dr. Justin Greenlee

  68. Experimental Second Passage of Chronic Wasting Disease (CWDmule deer) Agent to Cattle

    Article • Journal of Comparative Pathology, January 2006, Elsevier

    Dr. Justin Greenlee

  69. Experimental canine leptospirosis caused byLeptospira interrogansserovars pomona and bratislava

    Article • American Journal of Veterinary Research, October 2005, American Veterinary Medical Association (AVMA)

    Dr. Justin Greenlee

  70. Clinical and pathologic comparison of acute leptospirosis in dogs caused by two strains of Leptospira kirschneri serovar grippotyphosa

    Article • American Journal of Veterinary Research, August 2004, American Veterinary Medical Association (AVMA)

    Dr. Justin Greenlee

  71. An Improved Immunohistochemical Diagnostic Technique for Canine Leptospirosis using Antileptospiral Antibodies on Renal Tissue

    Article • Journal of Veterinary Diagnostic Investigation, January 2002, SAGE Publications

    Dr. Justin Greenlee