All Stories

  1. Allyl sulphides in olefin metathesis: catalyst considerations and traceless promotion of ring-closing metathesis
  2. Halide inhibition of the copper-catalysed azide–alkyne cycloaddition
  3. Faculty Opinions recommendation of Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with γ-thialysine by using a chemical mutagenesis strategy.
  4. Faculty Opinions recommendation of Dehydroalanine-based diubiquitin activity probes.
  5. Faculty Opinions recommendation of Insights into Aurora-A kinase activation using unnatural amino acids incorporated by chemical modification.
  6. Melamine and Melamine-Formaldehyde Polymers as Ligands for Palladium and Application to Suzuki–Miyaura Cross-Coupling Reactions in Sustainable Solvents
  7. Facile preparation of ammonium alginate-derived nanofibers carrying diverse therapeutic cargo
  8. High density growth of ZnO nanorods on cotton fabric enables access to a flame resistant composite
  9. An Operationally Simple Aqueous Suzuki–Miyaura Cross-Coupling Reaction for an Undergraduate Organic Chemistry Laboratory
  10. Faculty Opinions recommendation of Capturing a sulfenic acid with arylboronic acids and benzoxaborole.
  11. Faculty Opinions recommendation of Chemical sensing of polyols with shapeshifting boronic acids as a self-contained sensor array.
  12. Faculty Opinions recommendation of A genetically encoded acrylamide functionality.
  13. Faculty Opinions recommendation of A robustness screen for the rapid assessment of chemical reactions.
  14. Faculty Opinions recommendation of A facile strategy for selective incorporation of phosphoserine into histones.
  15. Faculty Opinions recommendation of A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
  16. Faculty Opinions recommendation of Ligand-free palladium-mediated site-specific protein labeling inside gram-negative bacterial pathogens.
  17. Faculty Opinions recommendation of Discovery of the antibiotic phosacetamycin via a new mass spectrometry-based method for phosphonic acid detection.
  18. Faculty Opinions recommendation of Hyperstability and substrate promiscuity in laboratory resurrections of Precambrian β-lactamases.
  19. Faculty Opinions recommendation of Late-stage deoxyfluorination of alcohols with PhenoFluor.
  20. Investigation of cotton functionalized with ZnO nanorods and its interaction with E. coli
  21. Prospects in the Total Synthesis of Protein Therapeutics
  22. Faculty Opinions recommendation of Integration of chemical catalysis with extractive fermentation to produce fuels.
  23. Faculty Opinions recommendation of Challenges for academic drug discovery.
  24. Faculty Opinions recommendation of Photochemical restoration of visual responses in blind mice.
  25. Faculty Opinions recommendation of Selective transformations of complex molecules are enabled by aptameric protective groups.
  26. Faculty Opinions recommendation of Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.
  27. Faculty Opinions recommendation of Photochemically driven redox chemistry induces protocell membrane pearling and division.
  28. Faculty Opinions recommendation of Reaction-based genetically encoded fluorescent hydrogen sulfide sensors.
  29. Faculty Opinions recommendation of Chemoenzymatic reversible immobilization and labeling of proteins without prior purification.
  30. Faculty Opinions recommendation of Chemical synthesis of homogeneous human glycosyl-interferon-β that exhibits potent antitumor activity in vivo.
  31. Faculty Opinions recommendation of Synthetic genetic polymers capable of heredity and evolution.
  32. Faculty Opinions recommendation of 2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms.
  33. Faculty Opinions recommendation of Site-selective bromination of vancomycin.
  34. Faculty Opinions recommendation of Chemical protein synthesis by chemoselective α-ketoacid-hydroxylamine (KAHA) ligations with 5-oxaproline.
  35. Faculty Opinions recommendation of A potent, versatile disulfide-reducing agent from aspartic acid.
  36. Faculty Opinions recommendation of Synergy of peptide and sugar in O-GlcNAcase substrate recognition.
  37. Faculty Opinions recommendation of Boronate-mediated biologic delivery.
  38. Faculty Opinions recommendation of Prions are a common mechanism for phenotypic inheritance in wild yeasts.
  39. Faculty Opinions recommendation of Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor.
  40. Faculty Opinions recommendation of Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library.
  41. Faculty Opinions recommendation of Thiacycloalkynes for copper-free click chemistry.
  42. Faculty Opinions recommendation of Natural product-inspired cascade synthesis yields modulators of centrosome integrity.
  43. Conversion of Cysteine into Dehydroalanine Enables Access to Synthetic Histones Bearing Diverse Post‐Translational Modifications
  44. Conversion of Cysteine into Dehydroalanine Enables Access to Synthetic Histones Bearing Diverse Post‐Translational Modifications
  45. Synthesis of (−)-α-Kainic Acid via TMSCl-Promoted Pd-Catalyzed Zinc-ene Cyclization of an Allyl Acetate
  46. A “Tag-and-Modify” Approach to Site-Selective Protein Modification
  47. A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates
  48. A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates
  49. Methods for converting cysteine to dehydroalanine on peptides and proteins
  50. Safe and Scalable Preparation of Barluenga's Reagent
  51. Faculty Opinions recommendation of A genetically encoded boronate-containing amino acid.
  52. Faculty Opinions recommendation of Chemical mutations of papain. The preparation of Ser 25- and Gly 25-papain.
  53. Faculty Opinions recommendation of A New Enzyme Containing a Synthetically Formed Active Site. Thiol-Subtilisin.
  54. Faculty Opinions recommendation of The conversion of serine at the active site of subtilisin to cysteine: a "chemical mutation".
  55. Chemical mutagenesis: selective post-expression interconversion of protein amino acid residues
  56. Olefin Cross-Metathesis on Proteins: Investigation of Allylic Chalcogen Effects and Guiding Principles in Metathesis Partner Selection
  57. Chemical Protein Modification
  58. ChemInform Abstract: A Convenient Catalyst for Aqueous and Protein Suzuki—Miyaura Cross‐Coupling.
  59. Site-selective chemoenzymatic construction of synthetic glycoproteins using endoglycosidases
  60. Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry
  61. A Convenient Catalyst for Aqueous and Protein Suzuki−Miyaura Cross-Coupling
  62. ChemInform Abstract: Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology
  63. ChemInform Abstract: Olefin Metathesis for Site‐Selective Protein Modification
  64. Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology
  65. Olefin Metathesis for Site‐Selective Protein Modification
  66. Enabling olefin metathesis on proteins: chemical methods for installation of S-allyl cysteine
  67. ChemInform Abstract: Allyl Sulfides Are Privileged Substrates in Aqueous Cross‐Metathesis: Application to Site‐Selective Protein Modification.
  68. Allyl Sulfides Are Privileged Substrates in Aqueous Cross-Metathesis: Application to Site-Selective Protein Modification
  69. ChemInform Abstract: From Disulfide‐ to Thioether‐Linked Glycoproteins.
  70. Chemical approaches to mapping the function of post‐translational modifications
  71. Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins
  72. From Disulfide‐ to Thioether‐Linked Glycoproteins
  73. From Disulfide‐ to Thioether‐Linked Glycoproteins
  74. Chemical site-selective prenylation of proteins
  75. Tristriazole ligand for use in the Cu-Catalyzed [3+2] azide-alkyne cycloaddition on protein surfaces
  76. Two Syntheses of (−)-Kainic Acid via Highly Stereoselective Zinc-ene Cyclizations
  77. Allyl Sulfones as Precursors to Allylzincs in the Palladium-Catalyzed Zinc-ene Cyclization:  Highly Efficient Synthesis of Enantiopure (−)-Erythrodiene