All Stories

  1. Parallel Kinetic Resolution of Intramolecular Furan Diels-Alder Cycloadducts via Asymmetric Hydroboration
  2. Synthesis of a Protected keto-Lysidine Analogue via Improved Preparation of Arabino-isoCytosine Nucleosides
  3. Synthesis of 3-Substituted Pyrrolidines via Palladium-Catalysed Hydroarylation
  4. Synthesis of 3-Substituted Pyrrolidines via Palladium-Catalysed Hydroarylation
  5. Synthesis of 3-Substituted Pyrrolidines via Palladium-Catalyzed Hydroarylation
  6. A Simple, Broad-Scope Nickel(0) Precatalyst System for the Direct Amination of Allyl Alcohols
  7. A Simple, Broad-Scope Nickel(0) Precatalyst System for the Direct Amination of Allyl Alcohols
  8. Riluzole–Triazole Hybrids as Novel Chemical Probes for Neuroprotection in Amyotrophic Lateral Sclerosis
  9. Catalytic C−C Bond Formation Using a Simple Nickel Precatalyst System: Base- and Activator-Free Direct C-Allylation by Alcohols and Amines
  10. Efficacy, pharmacokinetic and pharmacodynamic evaluation of apaziquone in the treatment of non-muscle invasive bladder cancer
  11. Catalytic sp3-sp3Functionalisation of Sulfonamides: Late-Stage Modification of Drug-Like Molecules
  12. Tandem Aryne-Capture/Sigmatropic Rearrangement as a Metal-Free Entry to Functionalized N -Aryl Pyrrolidines
  13. The creation and characterisation of a National Compound Collection: the Royal Society of Chemistry pilot
  14. Reaction Workup Planning: A Structured Flowchart Approach, Exemplified in Difficult Aqueous Workup of Hydrophilic Products
  15. An Improved Method for Difluorocyclopropanation of Alkenes
  16. 1.16 Epoxidation and Related Processes
  17. Catalytic Synthesis of Riboside-Amino Acid Hybrids
  18. Preparation and ring-opening reactions of N -diphenylphosphinyl vinyl aziridines
  19. A Robust First-Pass Protocol for the Heck–Mizoroki Reaction
  20. An Efficient Method for Reductive Amination of Carbonyl Compounds under Nonacidic Conditions
  21. Oxadiazole isomers: all bioisosteres are not created equal
  22. Probing the Effect of Allylic Substitution on Cyclic Ammonium Ylid Rearrangements
  23. Aziridine Synthesis via Nucleophilic Attack of Carbene Equivalents on Imines: the Aza-Darzens Reaction
  24. t-Butyltetramethylguanidine
  25. Sigmatropic rearrangements of ‘onium’ ylids
  26. A Low-Temperature Ammonium Ylid Rearrangement: Enhanced Reactivity Engendered by Rigidity
  27. Bidentates versus Monodentates in Asymmetric Hydrogenation Catalysis: Synergic Effects on Rate and Allosteric Effects on Enantioselectivity
  28. Hydroxyselanylation of acyloxycyclohex-3-enes
  29. Substituent effects in hydroxyiodination of 1,2-diacyloxycyclohex-3-enes
  30. Asymmetric ammonium ylid rearrangements: the effect of nitrogen asymmetry
  31. Trimethylsilyl Trifluoromethanesulfonate
  32. Double Coupling Reactions of 3,4-Bis(stannyl)furanone: Facile Preparation of Diaryl- and Dibenzylfuranones
  33. Stille Reactions of 2,3-Bis(stannyl)butenoates: An Unexpected Regioselectivity
  34. Synthesis of Aziridines
  35. Asymmetric aziridine synthesis by aza-Darzens reaction of N-diphenylphosphinylimines with chiral enolates. Part 2: Inversion of diastereoselectivity
  36. Asymmetric aziridine synthesis by aza-Darzens reaction of N-diphenylphosphinylimines with chiral enolates. Part 1: Formation of cis-aziridines
  37. Trifluoroacetic Anhydride
  38. Trifluoroacetic Anhydride
  39. A New Class of Ammonium Ylid for [2,3]-Sigmatropic Rearrangement Reactions:  ene-endo-Spiro Ylids
  40. Asymmetric [2,3]-Rearrangement of Glycine-Derived Allyl Ammonium Ylids
  41. First Efficient and General Copper-Catalyzed [2,3]-Rearrangement of Tetrahydropyridinium Ylids
  42. Copper(II)-Catalyzed [2,3]-Sigmatropic Rearrangement ofN-Methyltetrahydropyridinium Ylids
  43. Preparation and ring-opening reactions of N,O-bis(diphenylphosphinyl) hydroxymethylaziridine (‘Di-Dpp’)
  44. The First Preparation of β-Lactones by Radical Cyclization
  45. [2,3]-Sigmatropic rearrangements of didehydropiperidinium ylids
  46. Preparation and reactions of 3,4-bisstannyl-2(5H)furanones
  47. Aziridines: epoxides’ ugly cousins?
  48. t-Butyltetramethylguanidine
  49. Methyl Dichlorofluoroacetate
  50. (Z)-N-Methyl-N-phenylbenzohydrazonyl Bromide
  51. Trimethylsilyl Trifluoromethanesulfonate
  52. Methylsulfenyl Trifluoromethanesulfonate
  53. Disodium Phenanthrenide
  54. N-Bromoacetamide-Silver Acetate-Acetic Acid
  55. 3-Bromo-2-propen-1-ol
  56. 5-Nitro-3H-1,2-benzoxathioleS,S-Dioxide
  57. Preparation and Reactions of 3,4-Bis(tributylstannyl)-2(5 H )-furanone
  58. Factors influencing the regiochemistry of hydroxyiodination of 1,2-diacycloxycyclohex-3-enes
  59. Preparation and ring-opening reactions of N-Diphenylphosphinyl aziridines
  60. The asymmetric synthesis of aziridines
  61. Alcohols, ethers and phenols
  62. Further hydroxyiodination of 1-acetoxycyclohex-2-enes: Preparation of tetraacetyl conduritol D
  63. Alkyl Chalcogenides: Oxygen-based Functional Groups
  64. Preparation of 2-aryl and 2-heteroaryl substituted penems by palladium mediated cross coupling
  65. Direct preparation of N-diphenylphosphinoyl aziridines from 1,2-aminoalcohols utilizing nucleofugacity of diphenylphosphinates
  66. A practical alternative to sulfonyl activation of aziridines: Ring-opening of N-diphenylphosphinoyl aziridines by carbon nucleophiles
  67. Hydroxyselenation of acetoxycyclohex-2-ene
  68. Diastereospecific hydroxyiodination of 1-acetoxycyclohex-2-ene via intramolecular delivery of oxygen
  69. Alcohols, phenols, and ethers
  70. Diastereospecific hydroxyselenation of cyclohex-2-enyl phenylglycinates
  71. Amino acid synthesis via ring opening of N-sulphonyl aziridine-2-carboxylate esters with organometallic reagents.
  72. Graphical abstracts
  73. Preparation and reactions of 3- and 4-tributylstannyl-2-(5H)-furanones: Preparation of aryl furanones
  74. Preparation of a highly functionalized allylsilane for use in three-bond cascade reactions
  75. Enantioselective synthesis of monocerin and fusarentin ethers: Antifungal and insecticidal fungal metabolites.
  76. The synthesis of isotopically labelled N-acetylcysteamine thioesters utilising a baker's yeast reduction in D2O
  77. The ring opening of aziridine-2-carboxylate esters with organometallic reagents
  78. Reactions of a glycidyl radical equivalent with 2-functionalised allyl stannanes
  79. Improved synthesis of α-Methylene-γ-lactones organotin reagents