All Stories

  1. Silver-based monomer and coordination polymer with organic thiocyanate ligand: Structural, computational and antiproliferative activity study
  2. Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies
  3. Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors
  4. Synthesis and Evaluation of Pyrimidine Steroids as Antiproliferative Agents
  5. Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations
  6. Antiproliferative potential of 3β,5α,6β,7α-tetrahydroxyergosta-8(14),22-diene produced by Acremonium persicinum isolated from an alkaline crater lake in Puebla, Mexico
  7. Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids
  8. Antiproliferative activity of biomass extract from Pseudomonas cedrina
  9. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells
  10. Koanolide A, antiproliferative germacrane-type sesquiterpene lactone from Koanophyllon gibbosum
  11. Synthesis and antiproliferative activity of new 2-glyco-3-nitro-2H-chromenes
  12. New pyrazolyl-dibenzo[b,e][1,4]diazepinones: room temperature one-pot synthesis and biological evaluation
  13. Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea
  14. Hydroxyl alkyl ammonium ionic liquid assisted green and one-pot regioselective access to functionalized pyrazolodihydropyridine core and their pharmacological evaluation
  15. Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action
  16. Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies
  17. Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz
  18. Anti-Proliferative 1,4-Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst-Free, One-Pot Multi-Component Reaction
  19. Cover Feature: One Step Up in Antiproliferative Activity: The Ru-Zn Complex [RuCp(PPh3 )2 -µ-dmoPTA-1κP :2κ2 N ,N′ -ZnCl2 ](CF3 SO3 ) (Eur. J. Inorg. Chem. 43/2018)
  20. One Step Up in Antiproliferative Activity: The Ru-Zn Complex [RuCp(PPh3 )2 -µ-dmoPTA-1κP :2κ2 N ,N′ -ZnCl2 ](CF3 SO3 )
  21. Phytochemical Study of Senecio volckmannii Assisted by CASE-3D with Residual Dipolar Couplings and Isotropic 1H/13C NMR Chemical Shifts
  22. Selenazolyl-hydrazones as Novel Selective MAO Inhibitors With Antiproliferative and Antioxidant Activities: Experimental and In-silico Studies
  23. Chalcogen-containing phenolics as antiproliferative agents
  24. Synthesis of unprecedented steroidal spiro heterocycles as potential antiproliferative drugs
  25. A green multicomponent synthesis of tocopherol analogues with antiproliferative activities
  26. Antiproliferative Activity and Cytotoxicity of Some Medicinal Wood-Destroying Mushrooms from Russia
  27. Antiproliferative activity of new 2-glyco-3-nitro-1,2-dihydroquinolines and quinolines synthesized under solventless conditions promoted by neutral alumina
  28. Oxa/thiazole-tetrahydropyran triazole-linked hybrids with selective antiproliferative activity against human tumour cells
  29. Pinnatifidenyne-Derived Ethynyl Oxirane Acetogenins from Laurencia viridis
  30. Effect of electronic and steric properties of 8-substituted quinolines in gold(III) complexes: Synthesis, electrochemistry, stability, interactions and antiproliferative studies
  31. New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents
  32. Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl d-ribofuranosides
  33. DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells
  34. Novel synthesis of steroidal oximes and lactams and their biological evaluation as antiproliferative agents
  35. Efficient synthesis and biological evaluation of new benzopyran-annulated pyrano[2,3-c]pyrazole derivatives
  36. Enhancement of the antiproliferative activity of [RuCp(PPh3)2(dmoPTA-1κP)]+via its coordination to one {CoCl2} unit: synthesis, crystal structure and properties of [RuCp(PPh3)2-μ-dmoPTA-...
  37. New selenosteroids as antiproliferative agents
  38. Synthesis and antiproliferative activity of sulfa-Michael adducts and thiochromenes derived from carbohydrates
  39. Total synthesis of (+)-herboxidiene/GEX 1A
  40. Acanthamoeba castellanii : A new high-throughput method for drug screening in vitro
  41. Synthesis and antiproliferative activity of peracetylated 2-amino-1,2-dideoxy-1-nitro-d-glycero-l-manno and d-glycero-d-talo heptitols
  42. Synthesis of monomeric and dimeric steroids containing [1,2,4]triazolo[1,5-a]pyrimidines
  43. Synthesis and biological evaluation of crown ether acyl derivatives
  44. Synthesis and Antiproliferative Activity of [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)
  45. Influence of the configurational pattern of sp2-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties
  46. One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected α-amino esters
  47. Antiproliferative effect of extract from endophytic fungusCurvularia trifoliiisolated from the “Veracruz Reef System” in Mexico
  48. ent-Labdane Diterpenoids from the Aerial Parts of Eupatorium obtusissmum
  49. Inhibition of endotoxin-induced airway epithelial cell injury by a novel family of pyrrol derivates
  50. A catalyst- and solvent-free multicomponent synthesis and docking study of some new antiproliferative N5-allyl-quinolylpyrido[2,3-b][1,4]benzodiazepinone precursors
  51. Catalytically Generated Ferrocene-Containing Guanidines as Efficient Precursors for New Redox-Active Heterometallic Platinum(II) Complexes with Anticancer Activity
  52. Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A
  53. Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids
  54. Synthesis of Luffarin L and 16-epi-Luffarin L Using a Temporary Silicon-Tethered Ring-Closing Metathesis Reaction
  55. Synthesis and identification of unprecedented selective inhibitors of CK1ε
  56. Dienamine and Friedel-Crafts One-Pot Synthesis, and Antitumor Evaluation of Diheteroarylalkanals
  57. Synthesis and antiproliferative activity of glutamic acid-based dipeptides
  58. Biomimetic Synthesis of Two Salmahyrtisanes: Salmahyrtisol A and Hippospongide A
  59. Phenolic thio- and selenosemicarbazones as multi-target drugs
  60. ChemInform Abstract: Oxazole/Thiazole and Triazole Hybrids Based on α-Amino Acids.
  61. ChemInform Abstract: Direct Stereoselective Synthesis of Enantiomerically Pure anti-β-Amino Alcohols.
  62. Efficient synthesis of some new antiproliferative N-fused indoles and isoquinolines via 1,3-dipolar cycloaddition reaction in an ionic liquid
  63. Antileishmanial activity of sp2-iminosugar derivatives
  64. Direct Synthesis of Polybenzylated Glutamic Acid Monoesters: Disambiguation of N,N-Dibenzylglutamic Acid α- and γ-Benzyl Esters
  65. Antiproliferative Evaluation of N-sulfonyl-2-alkyl-six Membered Azacycles. A QSAR Study
  66. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives
  67. Oxazole/Thiazole and Triazole Hybrids Based on α-Amino Acids
  68. ChemInform Abstract: Facile and Efficient Addition of Terminal Alkynes to Benzotriazole Esters: Synthesis of D-Erythro-sphingosine Using Ynones as the Key Intermediate.
  69. Direct Stereoselective Synthesis of Enantiomerically Pure anti-β-Amino Alcohols
  70. QSAR on antiproliferative naphthoquinones based on a conformation-independent approach
  71. Synthesis and biological activity of polyalthenol and pentacyclindole analogues
  72. New modular structures constructed by click chemistry
  73. Synthesis and antiproliferative activity of α-branched α,β-unsaturated ketones
  74. Expanding the synthesis of new trans-sulfonamide platinum complexes: Cytotoxicity, SAR, fluorescent cell assays and stability studies
  75. Synthesis of hybrids compounds by Click Chemistry and their bioactivities
  76. Derivatives of grindelic acid: From a non-active natural diterpene to synthetic antitumor derivatives
  77. New strategy toward the diverted synthesis of oxidized abietane diterpenes via oxidation of 6,7-dehydroferruginol methyl ether with dimethyldioxirane
  78. Generation of artificial neural networks models in anticancer study
  79. Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand
  80. Synthesis and antiproliferative activity of the heterobimetallic complexes [RuClCp(PPh3)-μ-dmoPTA-1κP:2κ2N,N′-MCl2] (M = Co, Ni, Zn; dmoPTA = 3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)
  81. Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model
  82. ChemInform Abstract: β-Lapachone Analogues with Enhanced Antiproliferative Activity.
  83. In Vitro Synergistic Interaction between DTA0100 and Radiation in Human Cancer Cell Lines
  84. β-Lapachone analogs with enhanced antiproliferative activity
  85. Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations
  86. Reactivity and Biological Properties of a Series of Cytotoxic PtI2(amine)2 Complexes, Either cis or trans Configured
  87. Heterometallic platinum(ii) compounds with β-aminoethylferrocenes: synthesis, electrochemical behaviour and anticancer activity
  88. A modular approach to trim cellular targets in anticancer drug discovery
  89. Antiproliferative activity of dmoPTA–Ru(II) complexes against human solid tumor cells
  90. Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation
  91. Synthesis and Biological Evaluation of 1-Deoxy-5-hydroxysphingosine Derivatives
  92. Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitis-idaea and Maytenus spinosa
  93. ChemInform Abstract: An Enantioselective Approach to the Synthesis of Polycyclic Ethers
  94. ChemInform Abstract: Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero- Michael Addition. Part 5. Synthesis of All Diastereoisomers of 2,3,5,6- Tetrasubstituted Tetrahydropyrans.
  95. ChemInform Abstract: Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero- Michael Addition. Part 6. A Computational Study of the Anellation to 2, 3-Disubstituted Tetrahydropyrans.
  96. Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel “Rule-Breaker” Iodidoplatinum(II) Complex
  97. ChemInform Abstract: Antiproliferative Activity of Novel Benzo[b][1,6]naphthyridines in Human Solid Tumor Cell Lines.
  98. ChemInform Abstract: A General Approach to the Asymmetric Synthesis of Unsaturated Lipidic α-Amino Acids. The First Synthesis of α-Aminoarachidonic Acid.
  99. ChemInform Abstract: Enantiospecific Synthesis of α-Amino Acid Semialdehydes: A Key Step for the Synthesis of Unnatural Unsaturated and Saturated α-Amino Acids.
  100. ChemInform Abstract: Synthesis of Highly Substituted Cyclic Ethers and γ-Lactones in Their Enantiomeric Forms by Stereoselective Cyclizations
  101. ChemInform Abstract: Synthesis, in vitro Cytotoxicity and in vivo Antiinflammatory Activity of Long Chain 3-Amino-1,2-diols.
  102. Antimicrobial Drug Resistance (2 volumes). Edited by Douglas L. Mayers.
  103. ChemInform Abstract: Synthesis and in vitro Cytotoxicity of Novel Long Chain Busulfan Analogues.
  104. ChemInform Abstract: Chromium-Catalyzed Oxidation of (Homo-)Allylic and (Homo-)Propargylic Alcohols with Sodium Periodate to Ketones or Carboxylic Acids.
  105. Mitotic Arrest Induced by a Novel Family of DNA Topoisomerase II Inhibitors
  106. Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol
  107. Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines
  108. Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides
  109. ChemInform Abstract: Belizeanolide, a Cytotoxic Macrolide from the Dinoflagellate Prorocentrum belizeanum
  110. Belizeanolide, a Cytotoxic Macrolide from the DinoflagellateProrocentrum belizeanum
  111. Belizeanolide, a Cytotoxic Macrolide from the DinoflagellateProrocentrum belizeanum
  112. β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs. Part 2.
  113. γ-Lactones α,β- and β,γ-fused to carbocycles as novel antiproliferative drugs
  114. Cytotoxic effects of C-glycosides in HOS and HeLa cell lines
  115. Antiproliferative activity of 4-chloro-5,6-dihydro-2H-pyrans. Part 2: Enhancement of drug cytotoxicity
  116. Samarium(II) Promoted Stereoselective Synthesis of Antiproliferative cis-β-Alkoxy-γ-alkyl-γ-lactones.
  117. Antiproliferative activity of 2-alkyl-4-halopiperidines and 2-alkyl-4-halo-1,2,5,6-tetrahydropyridines in solid tumor cell lines
  118. Synthesis and Antiproliferative Activity of Novel Sugiol β-Amino Alcohol Analogues.
  119. Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol
  120. Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Part 2: Effect of side chain homologation
  121. Samarium(II) promoted stereoselective synthesis of antiproliferative cis-β-alkoxy-γ-alkyl-γ-lactones
  122. Iron(III)-Promoted Aza-Prins-Cyclization: Direct Synthesis of Six-Membered Azacycles.
  123. Abietane Diterpenoids fromSalvia pachyphyllaandS. clevelandiiwith Cytotoxic Activity against Human Cancer Cell Lines
  124. Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans
  125. Synthesis and antiproliferative activity of novel sugiol β-amino alcohol analogs
  126. One-Pot Synthesis and SAR Study of cis-2,6-Dialkyl-4-chloro-tetrahydropyrans.
  127. β′-Hydroxy-α,β-Unsaturated Ketones: A New Pharmacophore for the Design of Anticancer Drugs.
  128. One-pot synthesis and SAR study of cis-2,6-dialkyl-4-chloro-tetrahydropyrans
  129. A Short and Efficient Enantiomeric Synthesis of Antitumor Fused Tetrahydrofurans
  130. β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs
  131. Prins-Type Synthesis and SAR Study of Cytotoxic Alkyl Chloro Dihydropyrans
  132. Sphingolipids in Anticancer Therapy
  133. Molecular Simplification in Bioactive Molecules:  Formal Synthesis of (+)-Muconin
  134. Enhancement of Drug Cytotoxicity by Silicon Containing Groups
  135. Synthesis and Anti-Breast Cancer Activity of Tetrasubstituted Pyrrole Derivatives
  136. The tert-butyl dimethyl silyl group as an enhancer of drug cytotoxicity against human tumor cells
  137. Antiproliferative activity in HL60 cells by tetrasubstituted pyrroles: a structure–activity relationship study
  138. Detection of an alternatively spliced form of deoxycytidine kinase mRNA in the 2′-2′-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000
  139. Inhibition of the activity of the native γ-aminobutyric acidA receptor by metabolites of thyroid hormones: correlations with molecular modeling studies
  140. Enantioselective Transport by a Steroidal Guanidinium Receptor
  141. Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues
  142. The multilayered postconfluent cell culture as a model for drug screening
  143. Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates
  144. Selective cell kill of the combination of gemcitabine and cisplatin in multilayered postconfluent tumor cell cultures
  145. Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols
  146. Enantiospecific synthesis of α-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated α-amino acids
  147. Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael Addition. 6. A Computational Study of the Annelation to 2,3-Disubstituted Tetrahydropyrans
  148. A general approach to the enantiomeric synthesis of lipidic α-amino acids, peptides and vicinal amino alcohols