Contact

All Stories

  1. Silver-based monomer and coordination polymer with organic thiocyanate ligand: Structural, computational and antiproliferative activity study

    Article • Polyhedron, November 2019, Elsevier

    Dr. José M. Padrón

  2. Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies

    Article • European Journal of Medicinal Chemistry, November 2019, Elsevier

    Dr. José M. Padrón

  3. Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors

    Article • European Journal of Medicinal Chemistry, November 2019, Elsevier

    Dr. José M. Padrón

  4. Synthesis and Evaluation of Pyrimidine Steroids as Antiproliferative Agents

    Article • Molecules, October 2019, MDPI AG

    Dr. José M. Padrón

  5. Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations

    Article • European Journal of Medicinal Chemistry, October 2019, Elsevier

    Dr. José M. Padrón

  6. Antiproliferative potential of 3β,5α,6β,7α-tetrahydroxyergosta-8(14),22-diene produced by Acremonium persicinum isolated from an alkaline crater lake in Puebla, Mexico

    Article • Natural Product Research, September 2019, Taylor & Francis

    Dr. José M. Padrón, JAVIER FERNANDEZ, Alla Shnyreva

  7. Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids

    Article • Molecules, August 2019, MDPI AG

    Dr. José M. Padrón

  8. Antiproliferative activity of biomass extract from Pseudomonas cedrina

    Article • Electronic Journal of Biotechnology, July 2019, Elsevier

    Dr. José M. Padrón

  9. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells

    Article • Investigational New Drugs, June 2019, Springer Science + Business Media

    Dr. José M. Padrón

  10. Koanolide A, antiproliferative germacrane-type sesquiterpene lactone from Koanophyllon gibbosum

    Article • Tetrahedron Letters, June 2019, Elsevier

    Dr. José M. Padrón

  11. Synthesis and antiproliferative activity of new 2-glyco-3-nitro-2H-chromenes

    Article • Bioorganic Chemistry, June 2019, Elsevier

    Dr. José M. Padrón

  12. New pyrazolyl-dibenzo[b,e][1,4]diazepinones: room temperature one-pot synthesis and biological evaluation

    Article • Molecular Diversity, May 2019, Springer Science + Business Media

    Dr. José M. Padrón

  13. Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea

    Article • Journal of Natural Products, May 2019, American Chemical Society (ACS)

    Dr. José M. Padrón

  14. Hydroxyl alkyl ammonium ionic liquid assisted green and one-pot regioselective access to functionalized pyrazolodihydropyridine core and their pharmacological evaluation

    Article • Bioorganic Chemistry, May 2019, Elsevier

    Prof (Dr) Hitendra M. Patel,FRSC, Dr. José M. Padrón

  15. Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action

    Article • Molecules, March 2019, MDPI AG

    Dr. José M. Padrón

  16. Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies

    Article • Journal of Natural Products, March 2019, American Chemical Society (ACS)

    Dr Miguel A González-Cardenete, Dr. José M. Padrón, Dr. Marco A Loza-Mejía

  17. Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz

    Article • Plants, November 2018, MDPI AG

    Dr. José M. Padrón

  18. Anti-Proliferative 1,4-Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst-Free, One-Pot Multi-Component Reaction

    Article • ChemistrySelect, November 2018, Wiley

    Prof (Dr) Hitendra M. Patel,FRSC, Dr. José M. Padrón, Dr Ramesh L Gardas

  19. Cover Feature: One Step Up in Antiproliferative Activity: The Ru-Zn Complex [RuCp(PPh3 )2 -µ-dmoPTA-1κP :2κ2 N ,N′ -ZnCl2 ](CF3 SO3 ) (Eur. J. Inorg. Chem. 43/2018)

    Article • European Journal of Inorganic Chemistry, November 2018, Wiley

    Dr. José M. Padrón, Professor Antonio Romerosa

  20. One Step Up in Antiproliferative Activity: The Ru-Zn Complex [RuCp(PPh3 )2 -µ-dmoPTA-1κP :2κ2 N ,N′ -ZnCl2 ](CF3 SO3 )

    Article • European Journal of Inorganic Chemistry, October 2018, Wiley

    Dr. José M. Padrón, Professor Antonio Romerosa

  21. Phytochemical Study of Senecio volckmannii Assisted by CASE-3D with Residual Dipolar Couplings and Isotropic 1H/13C NMR Chemical Shifts

    Article • Journal of Natural Products, October 2018, American Chemical Society (ACS)

    Dr. José M. Padrón

  22. Selenazolyl-hydrazones as Novel Selective MAO Inhibitors With Antiproliferative and Antioxidant Activities: Experimental and In-silico Studies

    Article • Frontiers in Chemistry, July 2018, Frontiers

    Dr. José M. Padrón, Assoc. Prof. Alfonso T. Garcia-Sosa

  23. Chalcogen-containing phenolics as antiproliferative agents

    Article • Future Medicinal Chemistry, February 2018, Future Science

    Dr. José M. Padrón, José G Fernández-Bolaños

  24. Synthesis of unprecedented steroidal spiro heterocycles as potential antiproliferative drugs

    Article • European Journal of Medicinal Chemistry, January 2018, Elsevier

    Dr. José M. Padrón

  25. A green multicomponent synthesis of tocopherol analogues with antiproliferative activities

    Article • European Journal of Medicinal Chemistry, January 2018, Elsevier

    Dr. José M. Padrón, Dr Mariela Bollati-Fogolin

  26. Antiproliferative Activity and Cytotoxicity of Some Medicinal Wood-Destroying Mushrooms from Russia

    Article • International Journal of Medicinal Mushrooms, January 2018, Begell House

    Dr. José M. Padrón

  27. Antiproliferative activity of new 2-glyco-3-nitro-1,2-dihydroquinolines and quinolines synthesized under solventless conditions promoted by neutral alumina

    Article • New Journal of Chemistry, January 2018, Royal Society of Chemistry

    Dr. José M. Padrón

  28. Oxa/thiazole-tetrahydropyran triazole-linked hybrids with selective antiproliferative activity against human tumour cells

    Article • New Journal of Chemistry, January 2018, Royal Society of Chemistry

    Dr. José M. Padrón

  29. Pinnatifidenyne-Derived Ethynyl Oxirane Acetogenins from Laurencia viridis

    Article • Marine Drugs, December 2017, MDPI AG

    Dr. José M. Padrón

  30. Effect of electronic and steric properties of 8-substituted quinolines in gold(III) complexes: Synthesis, electrochemistry, stability, interactions and antiproliferative studies

    Article • Journal of Inorganic Biochemistry, September 2017, Elsevier

    Dr. José M. Padrón

  31. New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents

    Article • European Journal of Medicinal Chemistry, September 2017, Elsevier

    Dr. José M. Padrón

  32. Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl d-ribofuranosides

    Article • Bioorganic & Medicinal Chemistry Letters, August 2017, Elsevier

    Dr. José M. Padrón

  33. DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells

    Article • European Journal of Pharmaceutical Sciences, July 2017, Elsevier

    Dr. José M. Padrón

  34. Novel synthesis of steroidal oximes and lactams and their biological evaluation as antiproliferative agents

    Article • Steroids, June 2017, Elsevier

    Dr. José M. Padrón

  35. Efficient synthesis and biological evaluation of new benzopyran-annulated pyrano[2,3-c]pyrazole derivatives

    Article • Molecular Diversity, March 2017, Springer Science + Business Media

    Dr. José M. Padrón, Professor Rajni Kant

  36. Enhancement of the antiproliferative activity of [RuCp(PPh3)2(dmoPTA-1κP)]+via its coordination to one {CoCl2} unit: synthesis, crystal structure and properties of [RuCp(PPh3)2-μ-dmoPTA-...

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Dr. José M. Padrón, Professor Antonio Romerosa

  37. New selenosteroids as antiproliferative agents

    Article • Organic & Biomolecular Chemistry, January 2017, Royal Society of Chemistry

    Dr. José M. Padrón

  38. Synthesis and antiproliferative activity of sulfa-Michael adducts and thiochromenes derived from carbohydrates

    Article • New Journal of Chemistry, January 2017, Royal Society of Chemistry

    Dr. José M. Padrón

  39. Total synthesis of (+)-herboxidiene/GEX 1A

    Article • Organic & Biomolecular Chemistry, January 2017, Royal Society of Chemistry

    Dr. José M. Padrón

  40. Acanthamoeba castellanii : A new high-throughput method for drug screening in vitro

    Article • Acta Tropica, December 2016, Elsevier

    Dr. José M. Padrón

  41. Synthesis and antiproliferative activity of peracetylated 2-amino-1,2-dideoxy-1-nitro-d-glycero-l-manno and d-glycero-d-talo heptitols

    Article • Bioorganic Chemistry, December 2016, Elsevier

    Dr. José M. Padrón

  42. Synthesis of monomeric and dimeric steroids containing [1,2,4]triazolo[1,5-a]pyrimidines

    Article • Steroids, December 2016, Elsevier

    Dr. José M. Padrón

  43. Synthesis and biological evaluation of crown ether acyl derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, November 2016, Elsevier

    Dr. José M. Padrón

  44. Synthesis and Antiproliferative Activity of [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)

    Article • Inorganic Chemistry, July 2016, American Chemical Society (ACS)

    Dr. José M. Padrón, Professor Antonio Romerosa

  45. Influence of the configurational pattern of sp2-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties

    Article • Carbohydrate Research, June 2016, Elsevier

    Dr. José M. Padrón

  46. One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected α-amino esters

    Article • Beilstein Journal of Organic Chemistry, May 2016, Beilstein Institut

    Dr. José M. Padrón

  47. Antiproliferative effect of extract from endophytic fungusCurvularia trifoliiisolated from the “Veracruz Reef System” in Mexico

    Article • Pharmaceutical Biology, April 2016, Taylor & Francis

    Dr. José M. Padrón

  48. ent-Labdane Diterpenoids from the Aerial Parts of Eupatorium obtusissmum

    Article • Journal of Natural Products, March 2016, American Chemical Society (ACS)

    Dr. José M. Padrón

  49. Inhibition of endotoxin-induced airway epithelial cell injury by a novel family of pyrrol derivates

    Article • Laboratory Investigation, March 2016, Springer Science + Business Media

    Dr. José M. Padrón

  50. A catalyst- and solvent-free multicomponent synthesis and docking study of some new antiproliferative N5-allyl-quinolylpyrido[2,3-b][1,4]benzodiazepinone precursors

    Article • New Journal of Chemistry, January 2016, Royal Society of Chemistry

    Dr. José M. Padrón

  51. Catalytically Generated Ferrocene-Containing Guanidines as Efficient Precursors for New Redox-Active Heterometallic Platinum(II) Complexes with Anticancer Activity

    Article • Organometallics, November 2015, American Chemical Society (ACS)

    Dr. José M. Padrón

  52. Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A

    Article • Molecular Diversity, October 2015, Springer Science + Business Media

    Dr. José M. Padrón

  53. Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids

    Article • Molecules, July 2015, MDPI AG

    Dr. José M. Padrón

  54. Synthesis of Luffarin L and 16-epi-Luffarin L Using a Temporary Silicon-Tethered Ring-Closing Metathesis Reaction

    Article • The Journal of Organic Chemistry, May 2015, American Chemical Society (ACS)

    Dr. José M. Padrón

  55. Synthesis and identification of unprecedented selective inhibitors of CK1ε

    Article • European Journal of Medicinal Chemistry, May 2015, Elsevier

    Dr. José M. Padrón

  56. Dienamine and Friedel-Crafts One-Pot Synthesis, and Antitumor Evaluation of Diheteroarylalkanals

    Article • Chemistry - A European Journal, April 2015, Wiley

    Dr. José M. Padrón

  57. Synthesis and antiproliferative activity of glutamic acid-based dipeptides

    Article • Amino Acids, April 2015, Springer Science + Business Media

    Dr. José M. Padrón

  58. Biomimetic Synthesis of Two Salmahyrtisanes: Salmahyrtisol A and Hippospongide A

    Article • The Journal of Organic Chemistry, April 2015, American Chemical Society (ACS)

    Dr. José M. Padrón

  59. Phenolic thio- and selenosemicarbazones as multi-target drugs

    Article • European Journal of Medicinal Chemistry, April 2015, Elsevier

    Dr. José M. Padrón

  60. ChemInform Abstract: Oxazole/Thiazole and Triazole Hybrids Based on α-Amino Acids.

    Article • ChemInform, February 2015, Wiley

    Dr. José M. Padrón

  61. ChemInform Abstract: Direct Stereoselective Synthesis of Enantiomerically Pure anti-β-Amino Alcohols.

    Article • ChemInform, January 2015, Wiley

    Dr. José M. Padrón

  62. Efficient synthesis of some new antiproliferative N-fused indoles and isoquinolines via 1,3-dipolar cycloaddition reaction in an ionic liquid

    Article • New Journal of Chemistry, January 2015, Royal Society of Chemistry

    Narsidas Parmar, Dr. José M. Padrón, Professor Rajni Kant

  63. Antileishmanial activity of sp2-iminosugar derivatives

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr. José M. Padrón

  64. Direct Synthesis of Polybenzylated Glutamic Acid Monoesters: Disambiguation of N,N-Dibenzylglutamic Acid α- and γ-Benzyl Esters

    Article • Synlett, August 2014, Thieme Publishing Group

    Dr. José M. Padrón

  65. Antiproliferative Evaluation of N-sulfonyl-2-alkyl-six Membered Azacycles. A QSAR Study

    Article • Medicinal Chemistry, August 2014, Bentham Science Publishers

    Dr Gonzalo J. Mena-Rejón, Dr. José M. Padrón

  66. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives

    Article • European Journal of Medicinal Chemistry, July 2014, Elsevier

    Dr. José M. Padrón, Professor of Pharmaceutical Sciences Richard B. van Breemen

  67. Oxazole/Thiazole and Triazole Hybrids Based on α-Amino Acids

    Article • Synthesis, June 2014, Thieme Publishing Group

    Dr. José M. Padrón

  68. ChemInform Abstract: Facile and Efficient Addition of Terminal Alkynes to Benzotriazole Esters: Synthesis of D-Erythro-sphingosine Using Ynones as the Key Intermediate.

    Article • ChemInform, April 2014, Wiley

    Dr. José M. Padrón

  69. Direct Stereoselective Synthesis of Enantiomerically Pure anti-β-Amino Alcohols

    Article • The Journal of Organic Chemistry, April 2014, American Chemical Society (ACS)

    Dr. José M. Padrón

  70. QSAR on antiproliferative naphthoquinones based on a conformation-independent approach

    Article • European Journal of Medicinal Chemistry, April 2014, Elsevier

    Dr. José M. Padrón

  71. Synthesis and biological activity of polyalthenol and pentacyclindole analogues

    Article • European Journal of Medicinal Chemistry, February 2014, Elsevier

    Dr. José M. Padrón

  72. New modular structures constructed by click chemistry

    Article • December 2013, Editora Edgard Blucher, Ltda.

    Dr. José M. Padrón

  73. Synthesis and antiproliferative activity of α-branched α,β-unsaturated ketones

    Article • European Journal of Medicinal Chemistry, December 2013, Elsevier

    Dr. José M. Padrón

  74. Expanding the synthesis of new trans-sulfonamide platinum complexes: Cytotoxicity, SAR, fluorescent cell assays and stability studies

    Article • Journal of Inorganic Biochemistry, October 2013, Elsevier

    Dr. José M. Padrón

  75. Synthesis of hybrids compounds by Click Chemistry and their bioactivities

    Article • September 2013, Editora Edgard Blucher, Ltda.

    Dr. José M. Padrón

  76. Derivatives of grindelic acid: From a non-active natural diterpene to synthetic antitumor derivatives

    Article • European Journal of Medicinal Chemistry, September 2013, Elsevier

    Dr. José M. Padrón

  77. New strategy toward the diverted synthesis of oxidized abietane diterpenes via oxidation of 6,7-dehydroferruginol methyl ether with dimethyldioxirane

    Article • Tetrahedron Letters, August 2013, Elsevier

    Dr Juan Francisco Leon, Dr. José M. Padrón

  78. Generation of artificial neural networks models in anticancer study

    Article • Neural Computing and Applications, April 2013, Springer Science + Business Media

    Dr. José M. Padrón

  79. Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand

    Article • Dalton Transactions, January 2013, Royal Society of Chemistry

    Dr ADORACION GOMEZ QUIROGA, Dr. José M. Padrón

  80. Synthesis and antiproliferative activity of the heterobimetallic complexes [RuClCp(PPh3)-μ-dmoPTA-1κP:2κ2N,N′-MCl2] (M = Co, Ni, Zn; dmoPTA = 3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)

    Article • Dalton Transactions, January 2013, Royal Society of Chemistry

    Professor Antonio Romerosa, Dr. José M. Padrón

  81. Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model

    Article • PLoS ONE, November 2012, PLOS

    Dr. José M. Padrón

  82. ChemInform Abstract: β-Lapachone Analogues with Enhanced Antiproliferative Activity.

    Article • ChemInform, September 2012, Wiley

    Dr. José M. Padrón

  83. In Vitro Synergistic Interaction between DTA0100 and Radiation in Human Cancer Cell Lines

    Article • Anti-Cancer Agents in Medicinal Chemistry, August 2012, Bentham Science Publishers

    Dr. José M. Padrón

  84. β-Lapachone analogs with enhanced antiproliferative activity

    Article • European Journal of Medicinal Chemistry, July 2012, Elsevier

    Dr. José M. Padrón

  85. Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations

    Article • Phytochemistry, April 2012, Elsevier

    Dr. José M. Padrón

  86. Reactivity and Biological Properties of a Series of Cytotoxic PtI2(amine)2 Complexes, Either cis or trans Configured

    Article • Inorganic Chemistry, January 2012, American Chemical Society (ACS)

    Dr ADORACION GOMEZ QUIROGA, Dr. José M. Padrón, Dott Giuseppe Pieraccini

  87. Heterometallic platinum(ii) compounds with β-aminoethylferrocenes: synthesis, electrochemical behaviour and anticancer activity

    Article • Dalton Transactions, January 2012, Royal Society of Chemistry

    Dr. José M. Padrón

  88. A modular approach to trim cellular targets in anticancer drug discovery

    Article • Bioorganic & Medicinal Chemistry Letters, November 2011, Elsevier

    Dr. José M. Padrón

  89. Antiproliferative activity of dmoPTA–Ru(II) complexes against human solid tumor cells

    Article • Bioorganic & Medicinal Chemistry Letters, August 2011, Elsevier

    Professor Antonio Romerosa, Dr. José M. Padrón

  90. Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation

    Article • MedChemComm, January 2011, Royal Society of Chemistry

    Dr. José M. Padrón

  91. Synthesis and Biological Evaluation of 1-Deoxy-5-hydroxysphingosine Derivatives

    Article • European Journal of Organic Chemistry, December 2010, Wiley

    Dr. José M. Padrón

  92. Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitis-idaea and Maytenus spinosa

    Article • Phytochemistry, October 2010, Elsevier

    Dr. José M. Padrón

  93. ChemInform Abstract: An Enantioselective Approach to the Synthesis of Polycyclic Ethers

    Article • ChemInform, August 2010, Wiley

    Dr. José M. Padrón

  94. ChemInform Abstract: Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero- Michael Addition. Part 5. Synthesis of All Diastereoisomers of 2,3,5,6- Tetrasubstituted Tetrahydropyrans.

    Article • ChemInform, August 2010, Wiley

    Dr. José M. Padrón

  95. ChemInform Abstract: Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero- Michael Addition. Part 6. A Computational Study of the Anellation to 2, 3-Disubstituted Tetrahydropyrans.

    Article • ChemInform, August 2010, Wiley

    Dr. José M. Padrón

  96. Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel “Rule-Breaker” Iodidoplatinum(II) Complex

    Article • ACS Medicinal Chemistry Letters, July 2010, American Chemical Society (ACS)

    Dr ADORACION GOMEZ QUIROGA, Dr. José M. Padrón

  97. ChemInform Abstract: Antiproliferative Activity of Novel Benzo[b][1,6]naphthyridines in Human Solid Tumor Cell Lines.

    Article • ChemInform, July 2010, Wiley

    Dr. José M. Padrón

  98. ChemInform Abstract: A General Approach to the Asymmetric Synthesis of Unsaturated Lipidic α-Amino Acids. The First Synthesis of α-Aminoarachidonic Acid.

    Article • ChemInform, June 2010, Wiley

    Dr. José M. Padrón

  99. ChemInform Abstract: Enantiospecific Synthesis of α-Amino Acid Semialdehydes: A Key Step for the Synthesis of Unnatural Unsaturated and Saturated α-Amino Acids.

    Article • ChemInform, June 2010, Wiley

    Dr. José M. Padrón

  100. ChemInform Abstract: Synthesis of Highly Substituted Cyclic Ethers and γ-Lactones in Their Enantiomeric Forms by Stereoselective Cyclizations

    Article • ChemInform, June 2010, Wiley

    Dr. José M. Padrón

  101. ChemInform Abstract: Synthesis, in vitro Cytotoxicity and in vivo Antiinflammatory Activity of Long Chain 3-Amino-1,2-diols.

    Article • ChemInform, June 2010, Wiley

    Dr. José M. Padrón

  102. Antimicrobial Drug Resistance (2 volumes). Edited by Douglas L. Mayers.

    Article • ChemMedChem, May 2010, Wiley

    Dr. José M. Padrón

  103. ChemInform Abstract: Synthesis and in vitro Cytotoxicity of Novel Long Chain Busulfan Analogues.

    Article • ChemInform, May 2010, Wiley

    Dr. José M. Padrón

  104. ChemInform Abstract: Chromium-Catalyzed Oxidation of (Homo-)Allylic and (Homo-)Propargylic Alcohols with Sodium Periodate to Ketones or Carboxylic Acids.

    Article • ChemInform, May 2010, Wiley

    Dr. José M. Padrón

  105. Mitotic Arrest Induced by a Novel Family of DNA Topoisomerase II Inhibitors

    Article • Journal of Medicinal Chemistry, May 2010, American Chemical Society (ACS)

    Dr. José M. Padrón

  106. Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol

    Article • Bioorganic & Medicinal Chemistry, April 2010, Elsevier

    Dr. José M. Padrón

  107. Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines

    Article • Bioorganic & Medicinal Chemistry, September 2009, Elsevier

    Dr. José M. Padrón

  108. Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides

    Article • Bioorganic & Medicinal Chemistry, July 2009, Elsevier

    Dr. José M. Padrón

  109. ChemInform Abstract: Belizeanolide, a Cytotoxic Macrolide from the Dinoflagellate Prorocentrum belizeanum

    Article • ChemInform, April 2009, Wiley

    Dr. José M. Padrón

  110. Belizeanolide, a Cytotoxic Macrolide from the DinoflagellateProrocentrum belizeanum

    Article • Angewandte Chemie, January 2009, Wiley

    Dr. José M. Padrón

  111. Belizeanolide, a Cytotoxic Macrolide from the DinoflagellateProrocentrum belizeanum

    Article • Angewandte Chemie International Edition, January 2009, Wiley

    Dr. José M. Padrón

  112. β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs. Part 2.

    Article • ChemMedChem, November 2008, Wiley

    Dr. José M. Padrón

  113. γ-Lactones α,β- and β,γ-fused to carbocycles as novel antiproliferative drugs

    Article • Bioorganic & Medicinal Chemistry Letters, October 2008, Elsevier

    Dr. José M. Padrón

  114. Cytotoxic effects of C-glycosides in HOS and HeLa cell lines

    Article • Bioorganic & Medicinal Chemistry Letters, July 2007, Elsevier

    Dr. José M. Padrón

  115. Antiproliferative activity of 4-chloro-5,6-dihydro-2H-pyrans. Part 2: Enhancement of drug cytotoxicity

    Article • Bioorganic & Medicinal Chemistry Letters, June 2007, Elsevier

    Dr. José M. Padrón

  116. Samarium(II) Promoted Stereoselective Synthesis of Antiproliferative cis-β-Alkoxy-γ-alkyl-γ-lactones.

    Article • ChemInform, May 2007, Wiley

    Dr. José M. Padrón

  117. Antiproliferative activity of 2-alkyl-4-halopiperidines and 2-alkyl-4-halo-1,2,5,6-tetrahydropyridines in solid tumor cell lines

    Article • Bioorganic & Medicinal Chemistry Letters, May 2007, Elsevier

    Dr. José M. Padrón

  118. Synthesis and Antiproliferative Activity of Novel Sugiol β-Amino Alcohol Analogues.

    Article • ChemInform, March 2007, Wiley

    Dr. José M. Padrón

  119. Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol

    Article • Bioorganic & Medicinal Chemistry Letters, March 2007, Elsevier

    Dr. José M. Padrón

  120. Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Part 2: Effect of side chain homologation

    Article • Bioorganic & Medicinal Chemistry Letters, February 2007, Elsevier

    Dr. José M. Padrón

  121. Samarium(II) promoted stereoselective synthesis of antiproliferative cis-β-alkoxy-γ-alkyl-γ-lactones

    Article • Bioorganic & Medicinal Chemistry Letters, January 2007, Elsevier

    Dr. José M. Padrón

  122. Iron(III)-Promoted Aza-Prins-Cyclization: Direct Synthesis of Six-Membered Azacycles.

    Article • ChemInform, December 2006, Wiley

    Dr. José M. Padrón

  123. Abietane Diterpenoids fromSalvia pachyphyllaandS. clevelandiiwith Cytotoxic Activity against Human Cancer Cell Lines

    Article • Journal of Natural Products, December 2006, American Chemical Society (ACS)

    Dr. José M. Padrón

  124. Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans

    Article • Bioorganic & Medicinal Chemistry Letters, December 2006, Elsevier

    Dr. José M. Padrón

  125. Synthesis and antiproliferative activity of novel sugiol β-amino alcohol analogs

    Article • European Journal of Medicinal Chemistry, November 2006, Elsevier

    Dr Juan Francisco Leon, Dr. José M. Padrón

  126. One-Pot Synthesis and SAR Study of cis-2,6-Dialkyl-4-chloro-tetrahydropyrans.

    Article • ChemInform, September 2006, Wiley

    Dr. José M. Padrón

  127. β′-Hydroxy-α,β-Unsaturated Ketones: A New Pharmacophore for the Design of Anticancer Drugs.

    Article • ChemInform, July 2006, Wiley

    Dr. José M. Padrón

  128. One-pot synthesis and SAR study of cis-2,6-dialkyl-4-chloro-tetrahydropyrans

    Article • Bioorganic & Medicinal Chemistry Letters, June 2006, Elsevier

    Dr. José M. Padrón

  129. A Short and Efficient Enantiomeric Synthesis of Antitumor Fused Tetrahydrofurans

    Article • European Journal of Organic Chemistry, April 2006, Wiley

    Dr. José M. Padrón

  130. β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs

    Article • Bioorganic & Medicinal Chemistry Letters, April 2006, Elsevier

    Dr. José M. Padrón

  131. Prins-Type Synthesis and SAR Study of Cytotoxic Alkyl Chloro Dihydropyrans

    Article • ChemMedChem, March 2006, Wiley

    Dr. José M. Padrón

  132. Sphingolipids in Anticancer Therapy

    Article • Current Medicinal Chemistry, March 2006, Bentham Science Publishers

    Dr. José M. Padrón

  133. Molecular Simplification in Bioactive Molecules:  Formal Synthesis of (+)-Muconin

    Article • The Journal of Organic Chemistry, March 2006, American Chemical Society (ACS)

    Dr. José M. Padrón

  134. Enhancement of Drug Cytotoxicity by Silicon Containing Groups

    Article • Letters in Drug Design & Discovery, February 2006, Bentham Science Publishers

    Dr. José M. Padrón

  135. Synthesis and Anti-Breast Cancer Activity of Tetrasubstituted Pyrrole Derivatives

    Article • Letters in Drug Design & Discovery, November 2005, Bentham Science Publishers

    Dr. José M. Padrón

  136. The tert-butyl dimethyl silyl group as an enhancer of drug cytotoxicity against human tumor cells

    Article • Bioorganic & Medicinal Chemistry Letters, August 2005, Elsevier

    Dr. José M. Padrón

  137. Antiproliferative activity in HL60 cells by tetrasubstituted pyrroles: a structure–activity relationship study

    Article • Bioorganic & Medicinal Chemistry Letters, May 2005, Elsevier

    Dr. José M. Padrón

  138. Detection of an alternatively spliced form of deoxycytidine kinase mRNA in the 2′-2′-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000

    Article • Biochemical Pharmacology, August 2004, Elsevier

    Dr. José M. Padrón

  139. Inhibition of the activity of the native γ-aminobutyric acidA receptor by metabolites of thyroid hormones: correlations with molecular modeling studies

    Article • Brain Research, April 2004, Elsevier

    Dr. José M. Padrón

  140. Enantioselective Transport by a Steroidal Guanidinium Receptor

    Article • Chemistry - A European Journal, July 2002, Wiley

    Dr. José M. Padrón

  141. Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues

    Article • Bioorganic & Medicinal Chemistry Letters, March 2001, Elsevier

    Dr. José M. Padrón

  142. The multilayered postconfluent cell culture as a model for drug screening

    Article • Critical Reviews in Oncology/Hematology, November 2000, Elsevier

    Dr. José M. Padrón

  143. Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates

    Article • International Journal of Cancer, January 2000, Wiley

    Dr. José M. Padrón

  144. Selective cell kill of the combination of gemcitabine and cisplatin in multilayered postconfluent tumor cell cultures

    Article • Anti-Cancer Drugs, June 1999, Wolters Kluwer Health

    Dr. José M. Padrón

  145. Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols

    Article • Bioorganic & Medicinal Chemistry Letters, March 1999, Elsevier

    Dr. José M. Padrón

  146. Enantiospecific synthesis of α-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated α-amino acids

    Article • Tetrahedron Asymmetry, October 1998, Elsevier

    Dr. José M. Padrón

  147. Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael Addition. 6. A Computational Study of the Annelation to 2,3-Disubstituted Tetrahydropyrans

    Article • The Journal of Organic Chemistry, July 1997, American Chemical Society (ACS)

    Dr. José M. Padrón

  148. A general approach to the enantiomeric synthesis of lipidic α-amino acids, peptides and vicinal amino alcohols

    Article • Tetrahedron Asymmetry, March 1996, Elsevier

    Dr. José M. Padrón