All Stories

  1. Addition of long‐acting beta‐agonists to inhaled corticosteroids for asthma in preschool children: A systematic review
  2. Precision medicine to diagnose asthma in preschool children: comparison of clinical scores, lung function, biomarkers, and genetic tests
  3. Risk Factors and Mechanisms Leading to Preschool Recurrent Wheeze and Asthma
  4. Severe childhood asthma in low and middle-income countries
  5. Wheezing on admission: a marker for bronchiolitis severity and asthma development
  6. Intravenous magnesium sulfate for asthma exacerbations in children: Systematic review with meta-analysis
  7. New paradigms in acute viral bronchiolitis: Is it time to change our approach?
  8. A cost‐utility analysis of single maintenance and reliever (SMART) therapy as compared to step 3 fixed‐dose therapy in patients aged 12 years or more with uncontrolled asthma
  9. The wheezy infant: A viewpoint from low-middle income countries
  10. A critical analysis of the effect of OM‐85 for the prevention of recurrent respiratory tract infections or wheezing/asthma from systematic reviews with meta‐analysis
  11. Higher levels of insulin‐like growth factor‐1 in cord blood associate with risk of asthma at age 3
  12. On-Demand ICS + FABA Combinations in 6–11-Year-Old Children
  13. Early Prediction of Asthma
  14. Reactance Inversion in persistent asthma: artifact or airway narrowing marker?
  15. High altitude pulmonary edema in children: A systematic review
  16. Association of adenotonsillectomy with wheezing episodes in childhood: A secondary analysis of the Childhood Adenotonsillectomy Trial
  17. Respiratory virus type to guide predictive enrichment approaches in the management of the first episode of bronchiolitis: A systematic review
  18. Asthma in the Americas: An Update: A Joint Perspective from the Brazilian Thoracic Society, Canadian Thoracic Society, Latin American Thoracic Society, and American Thoracic Society
  19. The role of respiratory syncytial virus‐ and rhinovirus‐induced bronchiolitis in recurrent wheeze and asthma—A systematic review and meta‐analysis
  20. Breathing Patterns and Oxygenation Saturation During Sleep in Children Habitually Living at High Altitude in the Andes: A Systematic Review
  21. Bronchiolitis phenotypes identified by latent class analysis may influence the occurrence of respiratory sequelae
  22. Prevalence of filaggrin loss‐of‐function variants in Chilean population with and without atopic dermatitis
  23. Genes, environment, and developmental timing: New insights from translational approaches to understand early origins of respiratory diseases
  24. A cluster randomized trial of interferon ß-1a for the reduction of transmission of SARS-Cov-2: protocol for the Containing Coronavirus Disease 19 trial (ConCorD-19)
  25. “Reactance inversion” at low frequencies during lung function measurement by impulse oscillometry in children with persistent asthma#
  26. The asthma predictive index as a surrogate diagnostic tool in preschoolers: Analysis of a longitudinal birth cohort
  27. Management of asthma in childhood: study protocol of a systematic evidence update by the Paediatric Asthma in Real Life (PeARL) Think Tank
  28. Cost‐utility of omalizumab for the treatment of uncontrolled moderate‐to‐severe persistent pediatric allergic asthma in a middle‐income country
  29. Emergent Pneumonia in Children
  30. Maternal Obesity Is Associated With Higher Cord Blood Adipokines in Offspring Most Notably in Females
  31. Testing the Asthma Predictive Index as a diagnostic tool in preschoolers: analysis of a longitudinal birth cohort
  32. Normal values for respiratory sleep polygraphy in children aged 4 to 9 years at 2,560 m above sea level
  33. For which infants with viral bronchiolitis could it be deemed appropriate to use albuterol, at least on a therapeutic trial basis?
  34. Leptin in Cord Blood Associates with Asthma Risk at Age 3 in the Offspring of Women with Gestational Obesity
  35. Maternal obesity is associated with a sex-specific epigenetic programming in human neonatal monocytes
  36. Childhood asthma outcomes during the COVID-19 pandemic: Findings from the PeARL multi-national cohort
  37. Cost‐effectiveness analysis of phenotypic‐guided versus guidelines‐guided bronchodilator therapy in viral bronchiolitis
  38. The use of β2-adrenoreceptor agonists in viral bronchiolitis: scientific rationale beyond evidence-based guidelines
  39. Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden
  40. Challenges of COVID-19 in children in low- and middle-income countries
  41. Inversion of the reactance curve and X5 approx. are better parameters for measuring small-airway dysfunction in asthmatic children
  42. Adding nebulized corticosteroids to systemic corticosteroids for acute asthma in children: A systematic review with meta‐analysis
  43. Cost-effectiveness analysis of phenotypic-guided vs. guidelines-guided bronchodilator therapy in viral bronchiolitis
  44. Asthma and COVID‐19 in children: A systematic review and call for data
  45. Predicting the outcome of respiratory disease in wheezing infants using tidal flow-volume loop shape
  46. Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank
  47. Oxygen Saturation in Childhood at High Altitude: A Systematic Review
  48. Dexamethasone or prednisolone for asthma exacerbations in children: A cost‐effectiveness analysis
  49. Asthma and COVID-19 in children – a systematic review and call for data
  50. Predictors of response to medications for asthma in pediatric patients: A systematic review of the literature
  51. Early origins of allergy and asthma (ARIES): study protocol for a prospective prenatal birth cohort in Chile
  52. Phenotypical Sub-setting of the First Episode of Severe Viral Respiratory Infection Based on Clinical Assessment and Underlying Airway Disease: A Pilot Study
  53. The impact of viral bronchiolitis phenotyping: Is it time to consider phenotype-specific responses to individualize pharmacological management?
  54. Correction to: Efficacy of Macrolides on Acute Asthma or Wheezing Exacerbations in Children with Recurrent Wheezing: A Systematic Review and Meta‑analysis
  55. Bedside clinical assessment predicts recurrence after hospitalization due to viral lower respiratory tract infection in young children
  56. Direct medical costs of pediatric asthma exacerbations requiring hospital attendance in a middle-income country
  57. Expert artificial intelligence-based natural language processing characterises childhood asthma
  58. Metered‐dose inhalers vs nebulization for the delivery of albuterol in pediatric asthma exacerbations: A cost‐effectiveness analysis in a middle‐income country
  59. Efficacy of Macrolides on Acute Asthma or Wheezing Exacerbations in Children with Recurrent Wheezing: A Systematic Review and Meta-analysis
  60. Direct medical costs of RSV-related bronchiolitis hospitalizations in a middle-income tropical country
  61. Asthma and the Risk of Invasive Pneumococcal Disease: A Meta-analysis
  62. Predicting Asthma Using Clinical Indexes
  63. Solar radiation, air pollution, and bronchiolitis hospitalizations in Chile: An ecological study
  64. Advantage of inhaled corticosteroids as additional therapy to systemic corticosteroids for pediatric acute asthma exacerbations: a cost-effectiveness analysis
  65. Cost‐effectiveness of the utilization of “good practice” or the lack thereof according to a bronchiolitis evidence‐based clinical practice guideline
  66. Preschoolers with recurrent wheezing have a high prevalence of sleep disordered breathing
  67. The impact of asthma and its treatment on growth: an evidence‐based review
  68. Salbutamol and ipratropium by inhaler is superior to nebulizer in children with severe acute asthma exacerbation: Randomized clinical trial
  69. Daily inhaled corticosteroids or montelukast for preschoolers with asthma or recurrent wheezing: A systematic review
  70. The impact of asthma and its treatment on growth: an evidence-based review
  71. Relation between serum CC16 levels and asthma predictive index in pre-schoolers with recurrent wheezing
  72. Down Syndrome and the Risk of Severe RSV Infection: A Meta-analysis
  73. Cost Effectiveness of Pharmacological Treatments for Asthma: A Systematic Review
  74. Serum periostin is not related to asthma predictive index
  75. The relationship between inflammation and remodeling in childhood asthma: A systematic review
  76. Automated chart review utilizing natural language processing algorithm for asthma predictive index
  77. Usefulness of asthma predictive index in ascertaining asthma status of children using medical records: An explorative study
  78. Bronchodilators in bronchiolitis: Yes or no?
  79. What are the real effects of the Mediterranean diet on recurrent colds and their complications?
  80. A cost-effectiveness threshold analysis of a multidisciplinary structured educational intervention in pediatric asthma
  81. Differences between preschoolers with asthma and allergies in urban and rural environments
  82. IL-10 expression in macrophages from neonates born from obese mothers is suppressed by IL-4 and LPS/INFγ
  83. What Are the Effects of a Mediterranean Diet on Allergies and Asthma in Children?
  84. Factors predicting persistence of early wheezing through childhood and adolescence: a systematic review of the literature
  85. Airway tone dysfunction among pre-schoolers with positive asthma predictive index: A case–control study
  86. Relation between asthma and sleep disordered breathing in children: is the association causal?
  87. Caregiver's depressive symptoms and asthma control in children from an underserved community
  88. Risk and Protective Factors for Childhood Asthma: What Is the Evidence?
  89. Down's syndrome is a risk factor for severe lower respiratory tract infection due to respiratory syncytial virus
  90. Effect of foods and Mediterranean diet during pregnancy and first years of life on wheezing, rhinitis and dermatitis in preschoolers
  91. Epigenética y obesidad
  92. Increased prevalence of Mycoplasma pneumoniae serological positivity in Chilean young children
  93. Programación epigenética placentaria en restricción del crecimiento intrauterino
  94. Efficacy of oral corticosteroids in the treatment of acute wheezing episodes in asthmatic preschoolers: Systematic review with meta-analysis
  95. Sleep-disordered breathing in children with asthma: a systematic review on the impact of treatment
  96. Treatment of asthma in young children: evidence-based recommendations
  97. A new childhood asthma phenotype: obese with early menarche
  98. Epigenética en enfermedades alérgicas y asma
  99. Cost–utility analysis of once-daily versus twice-daily inhaled corticosteroid dosing for maintenance treatment of asthma in pediatric patients
  100. Urinary leukotriene and Bcl I polymorphism of glucocorticoid receptor gene in preschoolers with recurrent wheezing and high risk of asthma
  101. Conceptos generales de epigenética: proyecciones en pediatría
  102. Leukotriene receptor antagonists as maintenance or intermittent treatment in pre-school children with episodic viral wheeze
  103. Children under 12 months could benefit from a therapeutic trial with bronchodilators if the clinical response is positive
  104. Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children
  105. Maternal nutrition during pregnancy and risk of asthma, wheeze, and atopic diseases during childhood: a systematic review and meta-analysis
  106. Erratum
  107. Principal findings of systematic reviews for the management of acute bronchiolitis in children
  108. Many respiratory viruses have temporal association with meningococcal disease
  109. Tiotropium for the treatment of adolescents with moderate to severe symptomatic asthma: a systematic review with meta-analysis
  110. Principal findings of systematic reviews of acute asthma treatment in childhood
  111. Validation of a Spanish version of the childhood asthma control test (SC-ACT) for use in Spain
  112. Validación de la versión en español de la prueba de control del asma infantil (ACT) para su uso en España
  113. Asthma in Latin America
  114. Bronchodilators should be considered for all patients with acute bronchiolitis, but closely monitored for objectively measured clinical benefits
  115. Vitamin D levels and vitamin D receptor gene polymorphisms in asthmatic children: a case-control study
  116. Response
  117. Programación fetal de enfermedades crónicas: conceptos actuales y epigenética
  118. Methacholine challenge test by wheezing and oxygen saturation in preschool children with asthma
  119. What Is the Role of Tiotropium in Asthma?
  120. Another Predictive Score for Childhood Asthma: The Search Remains
  121. Utility of bronchodilator response for asthma diagnosis in Latino preschoolers
  122. Principal findings of systematic reviews for chronic treatment in childhood asthma
  123. Influence of asthma on sleep disordered breathing in children: A systematic review
  124. Does diffuse irrigation result in improved radiofrequency catheter ablation? A prospective randomized study of right atrial typical flutter ablation
  125. Postinfectious bronchiolitis obliterans in children: the South American contribution
  126. Cost‐utility analysis of daily versus intermittent inhaled corticosteroids in mild‐persistent asthma
  127. Chest physiotherapy for acute wheezing episodes: an inappropriate interpretation of the first trial in outpatient infants
  128. Validation of the Spanish Version of the Test for Respiratory and Asthma Control in Kids (TRACK) in a Population of Hispanic Preschoolers
  129. Chest physiotherapy is not clinically indicated for infants receiving outpatient care for acute wheezing episodes
  130. Heliox-driven β2-agonists nebulization for children and adults with acute asthma: a systematic review with meta-analysis
  131. Predictors of hospitalization for asthma in children: Results of a 1-year prospective study
  132. The necessity of having asthma predictive scores in children
  133. Inhaled versus systemic corticosteroids for acute asthma in children. A systematic review
  134. Daily vs. intermittent inhaled corticosteroids for recurrent wheezing and mild persistent asthma: A systematic review with meta-analysis
  135. Effect of obesity on bronchial hyperreactivity among Latino children
  136. Correlation between nitrites in induced sputum and asthma symptoms in asthmatic schoolchildren
  137. Obesity and asthma
  138. Postinfectious bronchiolitis obliterans
  139. Fractional Exhaled Nitric Oxide Has a Good Correlation with Asthma Control and Lung Function in Latino Children with Asthma
  140. Influence of Mediterranean diet on asthma in children: A systematic review and meta‐analysis
  141. Diagnóstico y tratamiento de la tos crónica en pediatría
  142. Cost-Utility Analysis of the Inhaled Steroids Available in a Developing Country for the Management of Pediatric Patients with Persistent Asthma
  143. Young Infants with Recurrent Wheezing and Positive Asthma Predictive Index Have Higher Levels of Exhaled Nitric Oxide
  144. The role of inhaled corticosteroids in management of asthma in infants and preschoolers
  145. Reply to letter of Drs Castro-Rodriguez and Rodrigo
  146. Efficacy of inhaled corticosteroids in wheezy infants/preschoolers
  147. Percutaneous Transhepatic Access for Ablation of Atypical Atrial Flutter in Complex Congenital Heart Disease
  148. Comparison of the bronchodilating effects of albuterol delivered by valved vs. non‐valved spacers in pediatric asthma
  149. Chest physiotherapy in paediatric patients hospitalised with community-acquired pneumonia: a randomised clinical trial
  150. A Systematic Review of Long-Acting  2-Agonists Versus Higher Doses of Inhaled Corticosteroids in Asthma
  151. International consensus on (ICON) pediatric asthma
  152. Infantile and preschool asthma
  153. Safety of long-acting β-agonists in asthma
  154. Addition Of A Long-Acting Beta2-Agonist Versus Higher Doses Of Inhaled Corticosteroids In Children With Asthma: A Systematic Review
  155. Urinary leukotriene excretion profile in children with exercise-induced asthma compared with controls: A preliminary study
  156. Dual Utility of Adenosine During Focal AF
  157. Does congenital heart disease severely jeopardise family life and pregnancies? Obstetrical history of women with congenital heart disease in a single tertiary centre
  158. Comparison of three combined pharmacological approaches with tiotropium monotherapy in stable moderate to severe COPD: A systematic review
  159. Exercise Challenge Test: Is a 15% Fall in FEV1Sufficient for Diagnosis?
  160. The Asthma Predictive Index: early diagnosis of asthma
  161. Discriminative properties of two predictive indices for asthma diagnosis in a sample of preschoolers with recurrent wheezing
  162. Many Respiratory Viruses May Trigger Meningococcal Diseases
  163. Safety of long-acting β agonists for the treatment of asthma: clearing the air
  164. The asthma predictive index remains a useful tool to predict asthma in young children with recurrent wheeze in clinical practice
  165. Is There a Potential Benefit to Increased Irrigation Channels During Radiofrequency Ablation? Results From a Two-Center Prospective Randomized Study
  166. Efficacy and Safety of Subcutaneous Omalizumab vs Placebo as Add-on Therapy to Corticosteroids for Children and Adults With Asthma
  167. Post Infectious Bronchiolitis Obliterans in Children
  168. Bronchial Hyperreactivity to Methacholine in Atopic Versus Nonatopic Asthmatic Schoolchildren and Preschoolers
  169. Bronchial Hyperreactivity to Methacholine in Atopic Versus Nonatopic Asthmatic Schoolchildren and Preschoolers
  170. The Asthma Predictive Index: A very useful tool for predicting asthma in young children
  171. Factors that affect the efficacy of inhaled corticosteroids for infants and young children
  172. Higher Metabolic Syndrome in Obese Asthmatic Compared to Obese Nonasthmatic Adolescent Males
  173. Olive Oil During Pregnancy Is Associated With Reduced Wheezing During The First Year Of Life Of The Offspring
  174. Complicated Forms of Tachycardia-Mediated Cardiomyopathy Associated with Idiopathic Left Ventricular Tachycardia
  175. Formoterol for acute asthma in the emergency department: a systematic review with meta-analysis
  176. Bronchodilators are central to the management of stable chronic obstructive pulmonary disease in the elderly
  177. Olive oil during pregnancy is associated with reduced wheezing during the first year of life of the offspring
  178. Guía ALERTA 2. América Latina y España: Recomendaciones para la prevención y el Tratamiento de la exacerbación Asmática
  179. Response to budesonide among atopic and non-atopic infants/preschoolers with recurrent wheezing
  180. The role of inhaled corticosteroids and montelukast in children with mild-moderate asthma: results of a systematic review with meta-analysis
  181. Effectiveness of Asthma Education with and Without a Self-Management Plan in Hospitalized Children
  182. Tiotropium and risk for fatal and nonfatal cardiovascular events in patients with chronic obstructive pulmonary disease: Systematic review with meta-analysis
  183. Safety and Efficacy of Combined Long-Acting β-Agonists and Inhaled Corticosteroids vs Long-Acting β-Agonists Monotherapy for Stable COPD
  184. Pre-excited or Not Pre-excited?
  185. Single oral dose of dexamethasone in outpatients with bronchiolitis: a placebo controlled trial
  186. Efficacy of Inhaled Corticosteroids in Infants and Preschoolers with Recurrent Wheezing and Asthma: A Systematic Review with Meta-Analysis.
  187. Atopic Asthmatic Schoolchildren Have Higher Bronchial Hyperreactivity to Methacoline Than Non-Atopic Asthmatics.
  188. Effectiveness of Asthma Education with and without Self-Management in Hospitalized Children.
  189. Efficacy of Inhaled Corticosteroids in Infants and Preschoolers With Recurrent Wheezing and Asthma: A Systematic Review With Meta-analysis
  190. Safety of regular use of long-acting beta agonists as monotherapy or added to inhaled corticosteroids in asthma. A systematic review
  191. Corrections
  192. Percent body fat, skinfold thickness or body mass index for defining obesity or overweight, as a risk factor for asthma in schoolchildren: which one to use in epidemiological studies?
  193. Wheezing and Asthma in childhood: an epidemiology approach
  194. Asthma, obesity, sedentary lifestyle and physical activity: an important issue still unresolved?
  195. Nitrites in induced sputum as a simple and cheap non-invasive marker of airway inflammation for asthmatic schoolchildren
  196. Mediterranean Diet as a Protective Factor for Wheezing in Preschool Children
  197. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach
  198. Factors associated to recurrent visits to the emergency department for asthma exacerbations in children: implications for a health education programme
  199. Risk factors for x-ray pneumonia in the first year of life and its relation to wheezing: a longitudinal study in a socioeconomic disadvantaged population
  200. Multidetector 16-slice CT scan evaluation of cavotricuspid isthmus anatomy before radiofrequency ablation
  201. Tratamiento de la crisis asmática en pediatría
  202. Tratamiento de la crisis asmática en pediatría
  203. Heightened bronchial hyperresponsiveness in the absence of heightened atopy in children with current wheezing and low-income status.
  204. Relación entre asma e infecciones virales
  205. Relación entre asma e infecciones virales
  206. HOW MANY ASTHMATIC PATIENTS HAVE ASTHMA?
  207. Erratum
  208. Comparison of tuberculin skin test response after three modalities of neonatal BCG vaccination
  209. Asthma attributable to atopy: does it depend on the allergen supply?
  210. Effects of active tobacco smoking on the prevalence of asthma-like symptoms in adolescents
  211. Clinical, functional, and epidemiological differences between atopic and nonatopic asthmatic children from a tertiary care hospital in a developing country
  212. Relación entre obesidad y asma
  213. Relationship Between Obesity and Asthma
  214. Assessing the Risk of Asthma in Infants and Pre-School Children
  215. ¿Cómo evaluar el riesgo de asma bronquial en lactantes y preescolares?
  216. Adenovirus pneumonia in infants and factors for developing bronchiolitis obliterans: A 5‐year follow‐up
  217. CORRECTION
  218. Differences in prevalence of asthma, rhinitis, and eczema between parental and self‐completed questionnaires in adolescents
  219. CORRECTION
  220. A different pattern of risk factors for atopic and non‐atopic wheezing in 9–12‐year‐old children
  221. Correction
  222. Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis
  223. Implicaciones del estudio GOAL en el asma infantil
  224. Authors' Response
  225. Neumonía eosinofílica crónica: A propósito de un caso y revisión de la literatura
  226. How pediatricians in Spain manage the first acute wheezing episode in an atopic infant. Results from the TRAP study
  227. Re: “Two new radiological findings to improve the diagnosis of bronchial foreign-body aspiration in children” by Girardi et al. (Pediatr Pulmonol 2004;38:261-264)
  228. β-agonists through metered-dose inhaler with valved holding chamber versus nebulizer for acute exacerbation of wheezing or asthma in children under 5 years of age: A systematic review with meta-analysis
  229. The use of spirometers and peak flow meters in the diagnosis and management of asthma among Spanish pediatricians. Results from the TRAP study
  230. Figure 1 (cropped) from Castro-Rodriguez
  231. Two new radiological findings to improve the diagnosis of bronchial foreign-body aspiration in children
  232. Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community‐acquired pneumonia in children
  233. Dog exposure in infancy decreases the subsequent risk of frequent wheeze but not of atopy
  234. Relation Between Infantile Colic and Asthma/Atopy: A Prospective Study in an Unselected Population
  235. Increased Incidence of Asthmalike Symptoms in Girls Who Become Overweight or Obese during the School Years
  236. Relation of Two Different Subtypes of Croup Before Age Three to Wheezing, Atopy, and Pulmonary Function During Childhood: A Prospective Study
  237. A Clinical Index to Define Risk of Asthma in Young Children with Recurrent Wheezing
  238. Siblings, Day-Care Attendance, and the Risk of Asthma and Wheezing during Childhood
  239. Randomized trial of salbutamol via metered-dose inhaler with spacer versus nebulizer for acute wheezing in children less than 2 years of age
  240. Helicobacter pylori is not a determinant factor of persistent diarrhoea or malnutrition in Peruvian children
  241. Association of Radiologically Ascertained Pneumonia Before Age 3 yr with Asthmalike Symptoms and Pulmonary Function During Childhood
  242. Relation between pulse oximetry and clinical score in children with acute wheezing less than 24 months of age
  243. Differentiation of osmotic and secretory diarrhoea by stool carbohydrate and osmolar gap measurements