All Stories

  1. Characterization of p53 p.T253I as a pathogenic mutation underlying Li-Fraumeni Syndrome

    Article • PLOS One, December 2025, PLOS

    Dr John August D'Orazio

  2. Next steps in melanocyte and melanoma research

    Article • Pigment Cell & Melanoma Research, October 2018, Wiley

    Professor Richard A Spritz, Dr John August D'Orazio, Fabian Filipp

  3. The melanocortin signaling cAMP axis accelerates repair and reduces mutagenesis of platinum-induced DNA damage

    Article • Scientific Reports, September 2017, Nature

    Dr John August D'Orazio

  4. Getting a tan without getting SIK

    Article • Pigment Cell & Melanoma Research, August 2017, Wiley

    Dr John August D'Orazio

  5. Divergence of cAMP signalling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes

    Article • Experimental Dermatology, April 2017, Wiley

    Dr John August D'Orazio

  6. Paracrine regulation of melanocyte genomic stability: a focus on nucleotide excision repair

    Article • Pigment Cell & Melanoma Research, April 2017, Wiley

    Dr John August D'Orazio

  7. Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis

    Article • Photochemistry and Photobiology, November 2016, Wiley

    Dr John August D'Orazio

  8. Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in Melanocytes

    Article • Journal of Investigative Dermatology, December 2015, Elsevier

    Dr John August D'Orazio

  9. Suprarenal Neuroblastoma Presenting in a Child With Infantile Scoliosis

    Article • Pediatric Blood & Cancer, November 2015, Wiley

    Dr John August D'Orazio

  10. Abstract A34: MC1R signaling reduces UV mutagenesis by ATR-mediated recruitment of XPA to photolesions

    Article • Cancer Research, July 2015, American Association for Cancer Research (AACR)

    Dr John August D'Orazio

  11. Melanocyte UV resistance: Feelin' the endothelin

    Article • Experimental Dermatology, April 2015, Wiley

    Dr John August D'Orazio

  12. Melanoma — Epidemiology, Risk Factors, and the Role of Adaptive Pigmentation

    Article • April 2015, IntechOpen

    Dr John August D'Orazio

  13. UV-independent induction of beta defensin 3 in neonatal human skin explants

    Article • F1000Research, February 2015, Faculty of 1000, Ltd.

    Dr John August D'Orazio

  14. Cutaneous Hormonal Control of Melanocyte DNA Repair through Camp Signaling

    Article • Journal of Carcinogenesis & Mutagenesis, January 2015, OMICS Publishing Group

    Dr John August D'Orazio

  15. Using large public data repositories to discover novel genetic mutations with prospective links to melanoma

    Article • BMC Bioinformatics, January 2015, Springer Science + Business Media

    Dr John August D'Orazio

  16. UV-independent induction of beta defensin 3 in neonatal human skin explants

    Article • F1000Research, November 2014, Faculty of 1000, Ltd.

    Dr John August D'Orazio

  17. The Melanocortin 1 Receptor (MC1R) Pathway Enhances Expression of MnSOD and Protects againstROS-Induced Oxidative Stress in Human Melanocytes

    Article • Free Radical Biology and Medicine, November 2014, Elsevier

    Dr John August D'Orazio

  18. Dyskeratosis congenita caused by a novel TERT point mutation in siblings with pancytopenia and exudative retinopathy

    Article • Pediatric Blood & Cancer, July 2014, Wiley

    Dr John August D'Orazio

  19. Ctr1-ing BRAF signaling with copper

    Article • Pigment Cell & Melanoma Research, June 2014, Wiley

    Dr John August D'Orazio

  20. PKA-Mediated Phosphorylation of ATR Promotes Recruitment of XPA to UV-Induced DNA Damage

    Article • Molecular Cell, June 2014, Elsevier

    Dr John August D'Orazio

  21. Pheochromocytoma in a Twelve-Year-Old Girl with SDHB-Related Hereditary Paraganglioma-Pheochromocytoma Syndrome

    Article • Case Reports in Genetics, January 2014, Hindawi Publishing Corporation

    Dr John August D'Orazio

  22. Urinary Tract Malignancies of Infancy and Young Childhood

    Article • October 2013, Springer Science + Business Media

    Dr John August D'Orazio

  23. Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

    Article • Journal of Visualized Experiments, September 2013, MyJove Corporation

    Dr John August D'Orazio

  24. A 14-Year-Old Girl with Blurry Vision and Pancytopenia

    Article • The Journal of Pediatrics, August 2013, Elsevier

    Dr John August D'Orazio

  25. UV Radiation and the Skin

    Article • International Journal of Molecular Sciences, June 2013, MDPI AG

    Dr John August D'Orazio

  26. Intracranial Hemorrhage and a White Blood Cell Count of Almost 1 Million Cells/μL

    Article • The Journal of Pediatrics, January 2013, Elsevier

    Dr John August D'Orazio

  27. ITP in Children

    Article • Journal of Pediatric Hematology/Oncology, January 2013, Wolters Kluwer Health

    Dr John August D'Orazio

  28. An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

    Article • Nature, October 2012, Nature

    Dr John August D'Orazio

  29. Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation

    Article • Experimental Dermatology, September 2012, Wiley

    Dr John August D'Orazio

  30. Chest Wall Ewing Sarcoma Presenting as Abdominal Pain in a 12-Year-Old Boy

    Article • The Journal of Pediatrics, December 2011, Elsevier

    Dr John August D'Orazio

  31. Anthocyanin-rich Fractions of Blackberry Extracts Reduce UV-induced Free Radicals and Oxidative Damage in Keratinocytes

    Article • Phytotherapy Research, May 2011, Wiley

    Dr John August D'Orazio

  32. Hypereosinophilic Syndrome Presenting as Acute Myocardial Infarction in an Adolescent

    Article • The Journal of Pediatrics, April 2011, Elsevier

    Dr John August D'Orazio

  33. B12 Deficient Megaloblastic Anemia in a Toddler with a History of Gastroschisis

    Article • The Journal of Pediatrics, March 2011, Elsevier

    Dr John August D'Orazio

  34. Central role for cAMP signaling in pigmentation and UV resistance

    Article • Cell Cycle, January 2011, Taylor & Francis

    Dr John August D'Orazio

  35. Stem cell factor rescues tyrosinase expression and pigmentation in discreet anatomic locations in albino mice

    Article • Pigment Cell & Melanoma Research, December 2009, Wiley

    Dr John August D'Orazio

  36. Purification and growth of melanocortin 1 receptor (Mc1r)-defective primary murine melanocytes is dependent on stem cell factor (SFC) from keratinocyte-conditioned media

    Article • In Vitro Cellular & Developmental Biology, July 2009, Springer Science + Business Media

    Dr John August D'Orazio

  37. In Vitro Skin Diffusion Study of Pure Forskolin versus a Forskolin-Containing Plectranthus barbatus Root Extract

    Article • Journal of Natural Products, April 2009, American Chemical Society (ACS)

    Dr John August D'Orazio

  38. Prolonged treatment of fair-skinned mice with topical forskolin causes persistent tanning and UV protection

    Article • Pigment Cell & Melanoma Research, April 2009, Wiley

    Dr John August D'Orazio

  39. SPONTANEOUS RESOLUTION OF A SINGLE LESION OF MYELOID LEUKEMIA CUTIS IN AN INFANT: Case Report and Discussion

    Article • Pediatric Hematology and Oncology, January 2008, Taylor & Francis

    Dr John August D'Orazio

  40. Response to Slominski et al.

    Article • Pigment Cell Research, July 2007, Wiley

    Dr John August D'Orazio

  41. Central Role of p53 in the Suntan Response and Pathologic Hyperpigmentation

    Article • Cell, March 2007, Elsevier

    Dr John August D'Orazio

  42. Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning

    Article • Nature, September 2006, Nature

    Dr John August D'Orazio