All Stories

  1. Anti-TTR Nanobodies Allow the Identification of TTR Neuritogenic Epitope Associated with TTR-Megalin Neurotrophic Activities

    Article • ACS Chemical Neuroscience, October 2018, American Chemical Society (ACS)

    Joao Gomes, Dr Sandra Macedo-Ribeiro

  2. Delivery of an anti-transthyretin Nanobody to the brain through intranasal administration reveals transthyretin expression and secretion by motor neurons

    Article • Journal of Neurochemistry, May 2018, Wiley

    Joao Gomes

  3. Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia

    Article • Cell Death and Differentiation, August 2016, Springer Science + Business Media

    Joao Gomes

  4. Transthyretin participates in beta-amyloid transport from the brain to the liver- involvement of the low-density lipoprotein receptor-related protein 1?

    Article • Scientific Reports, February 2016, Springer Science + Business Media

    Joao Gomes

  5. Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABAA Receptor Clustering and Contributes to Neuronal Death

    Article • Molecular Neurobiology, June 2015, Springer Science + Business Media

    Joao Gomes

  6. Transthyretin Induces Insulin-like Growth Factor I Nuclear Translocation Regulating Its Levels in the Hippocampus

    Article • Molecular Neurobiology, August 2014, Springer Science + Business Media

    Joao Gomes

  7. Spatiotemporal resolution of BDNF neuroprotection against glutamate excitotoxicity in cultured hippocampal neurons

    Article • Neuroscience, May 2013, Elsevier

    Joao Gomes

  8. Excitotoxicity Downregulates TrkB.FL Signaling and Upregulates the Neuroprotective Truncated TrkB Receptors in Cultured Hippocampal and Striatal Neurons

    Article • Journal of Neuroscience, March 2012, Society for Neuroscience

    Joao Gomes

  9. Cleavage of the vesicular glutamate transporters under excitotoxic conditions

    Article • Neurobiology of Disease, December 2011, Elsevier

    Joao Gomes

  10. Cleavage of the Vesicular GABA Transporter under Excitotoxic Conditions Is Followed by Accumulation of the Truncated Transporter in Nonsynaptic Sites

    Article • Journal of Neuroscience, March 2011, Society for Neuroscience

    Joao Gomes

  11. BDNF-Induced Changes in the Expression of the Translation Machinery in Hippocampal Neurons: Protein Levels and Dendritic mRNA

    Article • Journal of Proteome Research, October 2009, American Chemical Society (ACS)

    Joao Gomes

  12. Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2

    Article • Journal of Neurochemistry, October 2008, Wiley

    Joao Gomes

  13. Neurotrophin Signaling and Cell Survival

    Article • January 2007, Springer Science + Business Media

    Joao Gomes

  14. Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways

    Article • Cell Death and Differentiation, May 2005, Springer Science + Business Media

    Joao Gomes