All Stories

  1. Properties of Oak Veneer Dyed with Supercritical CO2 and Vacuum-Pressurized Assisted Natural Dyes
  2. Study on the Process Optimization of Peanut Coat Pigment Staining of Poplar Wood
  3. Research on the Dyeing Properties of Chinese Fir Using Ultrasonic-Assisted Mulberry Pigment Dyeing
  4. Electrochemical reaction of indole-tethered alkynes enabling stereoselective construction of tetrahydro-γ-carbolines
  5. Cascade Detrifluoroacetylation, C–S Bond Cleavage, and SN2′ Reaction of α,α-Difluorinated Gem-Diols with MBH Esters
  6. Rh‐Catalyzed Hydration/C−F Bond Cleavage of Fluorinated Diazoalkanes Enabling Synthesis of α‐Fluoro‐β‐ketophosphonates
  7. A review: Deoxy-fluorination of galactose – One of lignocellulosic biomass hydrolysates
  8. A three-component cycloaddition of alkyl trifluorodiazoethane for the synthesis of trifluoromethylated isoxazolines
  9. Electrochemical Annulation of Indole-Tethered Alkynes Enabling Synthesis of Exocyclic Alkenyl Tetrahydrocarbazoles
  10. Synthesis of Aminoalkyl Sclareolide Derivatives and Antifungal Activity Studies
  11. Immobilization of ZnIn2S4 on sodium alginate foam for efficient hexavalent chromium removal
  12. Access to cyclopropanes with geminal trifluoromethyl and difluoromethylphosphonate groups
  13. New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine
  14. Evolution and Future of Hetero‐ and Hydro‐Trifluoromethylations of Unsaturated C−C Bonds
  15. A Cu-promoted reaction of β-keto trifluoromethyl amines enabling stereoselective synthesis of trifluoromethylated aziridines
  16. Fluorine-containing drugs approved by the FDA in 2021
  17. Copper-catalyzed reaction of alkyl trifluoromethyl diazoalkane for the synthesis of trifluoromethyl allenes
  18. Carboxylic Acid O–H Insertion Reaction of β-Ester Diazos Enabling Synthesis of β-Acyloxy Esters
  19. Visible-light-irradiated tandem sulfonylation/cyclization of indole tethered alkenes for the synthesis of tetrahydrocarbazoles
  20. Ru-Catalyzed Hydrogen Atom Transfer/C–F Bond Cleavage of Difluoroalkyl Diazos with Hantzsch Ester via a Photocatalytic Radical Process
  21. Arylsulfonylation-Triggered Cyclization of 3-Alkenyl Indoles Enabling Synthesis of Tetrahydro-γ-carboline
  22. The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine
  23. Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives
  24. One‐Pot Reaction of (β‐Amino‐α,α‐difluoroethyl)phosphonates with Trifluoromethylated Ketones via Aza‐Wittig Reagents
  25. Facile synthesis of (β-chlorodifluoroethyl)phosphonates via chlorination reaction of difluoroalkyl diazo derivatives with HCl
  26. Successful trifluoromethoxy-containing pharmaceuticals and agrochemicals
  27. Visible-Light-Irradiated Cascade Reaction of Indole-Tethered Alkenes to Access Tetracyclic Tetrahydro-γ-carbolines
  28. Intramolecular Appel Reaction of Trifluoromethylated β-Keto Diazos Enabling Assembly of Trifluoromethylpyrazoles
  29. Assembly of tetracyclic tetrahydrocarbazoles via a visible-light promoted cascade process
  30. Assembly of trifluoromethylated fused tricyclic pyrazoles via cyclization of β-amino cyclic ketones
  31. Electrochemical multi-component reaction of potassium metabisulfite with alkenes and alcohols enabling synthesis of sulfonate esters
  32. Advances in the Development of Trifluoromethoxylation Reagents
  33. Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes
  34. Fluorine-containing pharmaceuticals approved by the FDA in 2020: Synthesis and biological activity
  35. [3+2] Cycloaddition reactions of β-diazo-α,α-difluoromethylphosphonates with α,β-unsaturated esters
  36. New pharmaceuticals approved by FDA in 2020: Small‐molecule drugs derived from amino acids and related compounds
  37. Tailor‐Made Amino Acids in Pharmaceutical Industry: Synthetic Approaches to Aza‐Tryptophan Derivatives
  38. Peptidomimetics and Peptide-Based Blockbuster Drugs
  39. Synthesis of Isothiazoles through N-Propargylsulfinylamide: TFA-Promoted Sulfinyl Group-Involved Intramolecular Cyclization
  40. Comparative study of different chiral ligands for dynamic kinetic resolution of amino acids
  41. Integration of MIL-101-NH2 into Cellulosic Foams for Efficient Cr(VI) Reduction under Visible Light
  42. Tailor-made amino acids in the design of small-molecule blockbuster drugs
  43. A Call for a Change in Policy Regarding the Necessity for SDE Tests to Validate the Veracity of the Outcome of Enantioselective Syntheses, the Inherent Chiral State of Natural Products, and Other Cases Involving Enantioenriched Samples
  44. Asymmetric Synthesis of N‐Fmoc‐(S)‐7‐aza‐tryptophan via Alkylation of Chiral Nucleophilic Glycine Equivalent
  45. Asymmetric Synthesis of α‐Difluorinated β‐Amino Sulfones through Detrifluoroacetylative Mannich Reactions
  46. Recommended Tests for the Self-Disproportionation of Enantiomers (SDE) to Ensure Accurate Reporting of the Stereochemical Outcome of Enantioselective Reactions
  47. Flurbiprofen: A Study of the Behavior of the Scalemate by Chromatography, Sublimation, and NMR
  48. Chemical Aspects of Human and Environmental Overload with Fluorine
  49. Recent Advances in Synthesis of Difluoromethylene Phosphonates for Biological Applications
  50. In Situ Generation of Unstable Difluoromethylphosphonate-Containing Diazoalkanes and Their Use in [3 + 2] Cycloaddition Reactions with Vinyl Sulfones
  51. Design of (β-diazo-α,α-difluoroethyl)phosphonates and their application as masked carbenes in visible light-promoted coupling reactions with sulfonic acids
  52. Electrochemical Approaches for Preparation of Tailor-Made Amino Acids
  53. Electrosynthesis of functionalized tetrahydrocarbazolesviasulfonylation triggered cyclization reaction of indole derivatives
  54. Esterification of Carboxylic Acids with (β-Diazo-α,α-difluoroethyl)phosphonates under Photochemical Conditions
  55. Asymmetric synthesis of (S)‐3‐methyleneglutamic acid and its N‐Fmoc derivative via Michael addition–elimination reaction of chiral glycine Ni (II) complex with enol tosylates
  56. Sulfuration‐Triggered Radical Cyclization of o ‐Cyanoarylacrylamides to 3‐Thiomethylated Quinoline‐2,4‐dione
  57. Cyclic tailor-made amino acids in the design of modern pharmaceuticals
  58. Electrophilic fluorination using PhIO/HF·THF reagent
  59. Asymmetric synthesis of (S)‐α‐(octyl)glycine via alkylation of Ni(II) complex of chiral glycine Schiff base
  60. Recent Developments in the Asymmetric Detrifluoroacetylative Reactions of in situ Generated Mono-Fluorinated Enolates
  61. Next generation organofluorine containing blockbuster drugs
  62. Asymmetric Mannich reactions of (S)-N-tert-butylsulfinyl-3,3,3-trifluoroacetaldimines with yne nucleophiles
  63. Fluorine-containing drugs approved by the FDA in 2019
  64. Tailor-made amino acid-derived pharmaceuticals approved by the FDA in 2019
  65. Tailor‐Made Amino Acids and Fluorinated Motifs as Prominent Traits in Modern Pharmaceuticals
  66. Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature
  67. Synthesis of Ahod Moiety of Ralstonin A Using Amino Acid Schiff Base Ni(II)‐Complex Chemistry
  68. The Ruthenium‐Catalyzed Domino Cross Enyne Metathesis/Ring‐Closing Metathesis in the Synthesis of Enantioenriched Nitrogen‐Containing Heterocycles
  69. Kitamura Electrophilic Fluorination Using HF as a Source of Fluorine
  70. Michael addition reactions of chiral glycine Schiff base Ni (II)‐complex with 1‐(1‐phenylsulfonyl)benzene
  71. Asymmetric Synthesis of Fluorinated Monoterpenic Alkaloid Derivatives from Chiral Fluoroalkyl Aldimines via the Pauson‐Khand Reaction
  72. Large-Scale Synthesis of the Glycine Schiff Base Ni(II) Complex Derived from (S)- and (R)-N-(2-Benzoyl-4-chlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-2-pyrrolidinecarboxamide
  73. A Selectfluor-promoted oxidative reaction of disulfides and amines: access to sulfinamides
  74. Applications of fluorine-containing amino acids for drug design
  75. Asymmetric Synthesis of 4,4‐(Difluoro)glutamic Acid via Chiral Ni(II)‐Complexes of Dehydroalanine Schiff Bases. Effect of the Chiral Ligands Structure on the Stereochemical Outcome
  76. Chemistry of electrochemical oxidative reactions of sulfinate salts
  77. Selectfluor-Promoted Twofold Sulfination of Alcohols for the Synthesis of Sulfinic Ester from Diaryldisulfides
  78. Preparative Method for Asymmetric Synthesis of (S)-2-Amino-4,4,4-trifluorobutanoic Acid
  79. Detrifluoroacetylative in Situ Generated Cyclic Fluorinated Enolates for the Preparation of Compounds Featuring a C–F Stereogenic Center
  80. Development of Hamari Ligands for Practical Asymmetric Synthesis of Tailor-Made Amino Acids
  81. Perfluoro-3-ethyl-2,4-dimethyl-3-pentyl persistent radical: A new reagent for direct, metal-free radical trifluoromethylation and polymer initiation
  82. The self-disproportionation of enantiomers (SDE) via column chromatography of β-amino-α,α-difluorophosphonic acid derivatives
  83. Electrochemical Alkoxysulfonylation Difunctionalization of Styrene Derivatives Using Sodium Sulfinates as Sulfonyl Sources
  84. Practical Method for Preparation of (S)-2-Amino-5,5,5-trifluoropentanoic Acid via Dynamic Kinetic Resolution
  85. Fluorine‐Containing Drugs Approved by the FDA in 2018
  86. Asymmetric Vinylogous Mukaiyama‐Mannich Reactions of Heterocyclic Siloxy Dienes with Ellman's Fluorinated Aldimines
  87. Large‐Scale Asymmetric Synthesis of Fmoc‐(S)‐2‐Amino‐6,6,6‐Trifluorohexanoic Acid
  88. Ni-catalyzed deaminative cross-electrophile coupling of Katritzky salts with halides via C─N bond activation
  89. Optical Resolution of Rimantadine
  90. Convenient Asymmetric Synthesis of Fmoc-(S)-6,6,6-Trifluoro-Norleucine
  91. Effect of substituents on the configurational stability of the stereogenic nitrogen in metal(II) complexes of α‐amino acid Schiff bases
  92. The self-disproportionation of enantiomers (SDE) of amino acids and their derivatives
  93. Catalytic enantioselective Michael addition reactions between in situ detrifluoroacetylatively generated 3-fluorooxindole-derived enolates and 1-(1-(phenylsulfonyl)vinylsulfonyl)benzene
  94. Recent Advances on the Electrochemical Difunctionalization of Alkenes/Alkynes
  95. Chromatographic approach to study the configurational stability of Ni(II) complexes of amino‐acid Schiff bases possessing stereogenic nitrogen
  96. The self‐disproportionation of enantiomers (SDE): The effect of scaling down, potential problems versus prospective applications, possible new occurrences, and unrealized opportunities?
  97. Expedient Asymmetric Synthesis of (S)-2-Amino-4,4,4-trifluorobutanoic Acid via Alkylation of Chiral Nucleophilic Glycine Equivalent
  98. Electrochemical Dehydrogenative Phosphorylation of Alcohols for the Synthesis of Organophosphinates
  99. Chemistry of detrifluoroacetylativelyin situgenerated fluoro-enolates
  100. Metal-Free Functionalization of Alkanes
  101. Recent progress in the application of fluorinated chiral sulfinimine reagents
  102. Electrochemical Alkynyl/Alkenyl Migration for the Radical Difunctionalization of Alkenes
  103. A novel fluorinated triazole derivative suppresses macrophage activation and alleviates experimental colitis via a Twist1-dependent pathway
  104. Merging Photoredox and Copper Catalysis: Enantioselective Radical Cyanoalkylation of Styrenes
  105. Palladium‐Catalyzed Asymmetric Allylic Alkylations of Colby Pro‐Enolates with MBH Carbonates: Enantioselective Access to Quaternary C−F Oxindoles
  106. Copper-Catalyzed Multicomponent Reaction of DABCO·(SO2)2, Alcohols, and Aryl Diazoniums for the Synthesis of Sulfonic Esters
  107. Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs
  108. Radical reactions of aryl alkynoates in organic synthesis: Recent advances
  109. Copper‐Catalyzed Oxidative Reaction of β‐Keto Sulfones with Alcohols via C−S Bond Cleavage: Reaction Development and Mechanism Study
  110. Axially chiral Ni(II) complexes of α‐amino acids: Separation of enantiomers and kinetics of racemization
  111. Synthesis of Chiral Sulfonyl Lactones via Copper‐Catalyzed Asymmetric Radical Reaction of DABCO⋅(SO2)
  112. Asymmetric Vinylogous Mannich‐Type Addition of α,α‐Dicyanoalkenes to α‐Fluoroalkyl Sulfinyl Imines
  113. Mannich-type addition of 1,3-dicarbonyl compounds to chiral tert-butanesulfinyltrifluoroacetaldimines. Mechanistic aspects and chiroptical studies
  114. An electrochemical oxidative homo-coupling reaction of imidazopyridine heterocycles to biheteroaryls
  115. Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome
  116. Electrochemical oxidative radical oxysulfuration of styrene derivatives with thiols and nucleophilic oxygen sources
  117. The self-disproportionation of enantiomers (SDE): a menace or an opportunity?
  118. Chemoselective SN2′ Allylations of Detrifluoroacetylatively In Situ Generated 3-Fluoroindolin-2-one-Derived Tertiary Enolates with Morita–Baylis–Hillman Carbonates
  119. A Jak2-selective inhibitor potently reverses the immune suppression by modulating the tumor microenvironment for cancer immunotherapy
  120. Unusual reactivity of fluoro-enolates with dialkyl azodicarboxylates: Synthesis of isatin-hydrazones
  121. Access to Alkyl-Substituted Lactone via Photoredox-Catalyzed Alkylation/Lactonization of Unsaturated Carboxylic Acids
  122. Diastereoselective Regiodivergent Mannich Versus Tandem Mannich‐Cyclization Reactions
  123. Visible-Light Photoredox Catalyzed Oxidative/Reductive Cyclization Reaction of N-Cyanamide Alkenes for the Synthesis of Sulfonated Quinazolinones
  124. Photoredox-Catalyzed Cascade Difluoroalkylation and Intramolecular Cyclization for Construction of Fluorinated γ-Butyrolactones
  125. Catalytic Enantioselective Michael Addition Reactions of Tertiary Enolates Generated by Detrifluoroacetylation
  126. β‐Amino‐γ,γ‐difluoro‐ω‐phosphonoglutamic Acid Derivatives: An Unexplored, Multifaceted Structural Type of Tailor‐Made α‐Amino Acids
  127. Detrifluoroacetylative generation and chemistry of fluorine containing tertiary enolates
  128. Ni-Catalyzed Reductive Cross-Coupling of Amides with Aryl Iodide Electrophiles via C–N Bond Activation
  129. Detrifluoroacetylative cascade reactions of bicyclic fluoro-enolates with ortho -phthalaldehyde: Aspects of reactivity, diastereo- and enantioselectivity
  130. Asymmetric Synthesis of Quaternary β‐Perfluorophenyl‐β‐amino‐indolin‐2‐ones
  131. Copper(II) Acetate‐Catalyzed Hydroxysulfenylation‐Initiated Lactonization of Unsaturated Carboxylic Acids with Oxygen as Oxidant and Oxygenation Reagent
  132. Catalytic Enantioselective Cyano‐Trifluoromethylation of Styrenes
  133. Solvent-free, uncatalyzed asymmetric “ene” reactions of N-tert-butylsulfinyl-3,3,3-trifluoroacetaldimines: a general approach to enantiomerically pure α-(trifluoromethyl)tryptamines
  134. Asymmetric synthesis of C–F quaternary α-fluoro-β-amino-indolin-2-ones via Mannich addition reactions; facets of reactivity, structural generality and stereochemical outcome
  135. Catalytic asymmetric aldol addition reactions of 3-fluoro-indolinone derived enolates
  136. Metal-free nitroxyl radical-mediated β-C(sp3)–H amination of saturated ketones with heteroaryl halides: multiple roles of TEMPO
  137. Transition-metal-free oxidative reaction of hydrazines and potassium metabisulfite for preparation of sulfonohydrazides
  138. Copper‐Catalyzed Selective Aerobic Oxidative Cascade Reaction of Hydrazines, DABSO, and Amines for the Direct Synthesis of Sulfonamides
  139. Synthesis of Trisubstituted Vinyl Sulfides via Oxidative Thiolation Initiated Cascade Reaction of Alkynoates with Thiols
  140. Development and Evaluation of Different Methods for Preparation of Fluorine‐Containing ( R )‐ and ( S )‐ N ‐ ...
  141. Cu-Catalyzed Deoxygenative C2-Sulfonylation Reaction of Quinoline N-Oxides with Sodium Sulfinate
  142. N‐tert‐Butylsulfinyl‐3,3,3‐trifluoroacetaldimine: Versatile Reagent for Asymmetric Synthesis of Trifluoromethyl‐Containing Amines and Amino Acids of Pharmaceutical Importance
  143. N-Iodosuccinimide-Initiated Spirocyclopropanation of Styrenes with 1,3-Dicarbonyl Compound for the Synthesis of Spirocyclopropanes
  144. Detrifluoroacetylative in Situ Generation of Free 3-Fluoroindolin-2-one-Derived Tertiary Enolates: Design, Synthesis, and Assessment of Reactivity toward Asymmetric Mannich Reactions
  145. Catalytic asymmetric detrifluoroacetylative aldol reactions of aliphatic aldehydes for construction of C-F quaternary stereogenic centers
  146. New Chiral Reagent for Installation of Pharmacophoric (S)‐ or (R)‐2‐(Alkoxyphosphono)‐1‐amino‐2,2‐difluoroethyl Groups
  147. Cascade alkylarylation of substituted N-allylbenzamides for the construction of dihydroisoquinolin-1(2H)-ones and isoquinoline-1,3(2H,4H)-diones
  148. N-Iodosuccinimide-Promoted Cascade Trifunctionalization of Alkynoates: Access to 1,1-Diiodoalkenes
  149. Catalytic cascade aldol–cyclization of tertiary ketone enolates for enantioselective synthesis of keto-esters with a C–F quaternary stereogenic center
  150. Sunlight-promoted cyclization versus decarboxylation in the reaction of alkynoates with N-iodosuccinimide: easy access to 3-iodocoumarins
  151. Copper‐Catalyzed Aerobic Oxidative Reaction of Sulfonyl Hydrazides with Alcohols: An Easy Access to Sulfinates
  152. Asymmetric synthesis of β-trifluoromethyl-β-amino acids, including highly sterically constrained α,α-dialkyl derivatives
  153. Oxidative Difunctionalization of Alkynoates through Alkylation and Migration Decarboxylative Arylation
  154. Recent Progress in the in situ Detrifluoro­acetylative Generation of Fluoro Enolates and Their Reactions with Electrophiles
  155. Generalized Approach to Asymmetric Synthesis of β‐Substituted β‐Amino Acids Bearing CHF2, CBrF2, and CClF2 Groups
  156. Carbonyl group coordination preferences in square-planar NiII and PdII complexes of pentadentate ligands by electron-withdrawing/donating substituents
  157. Cyclization reaction of N -allylbenzothioamide for direct construction of thiazole and thiazoline
  158. Hydroxyalkylation-Initiated Radical Cyclization ofN-Allylbenzamide for Direct Construction of Isoquinolinone
  159. Synthesis of α,α-difluoro-β-amino carbonyl-containing sulfonamides and related compounds
  160. Assembly of Fluorinated Quaternary Stereogenic Centers through Catalytic Enantioselective Detrifluoroacetylative Aldol Reactions
  161. Metal-Free Oxidative Functionalization of a C(sp3)–H Bond Adjacent to Nitrogen and Intramolecular Aromatic Cyclization for the Preparation of 6-Amidophenanthridines
  162. Synthesis of Trifluoromethyl-Containing Vicinal Diamines by Asymmetric Decarboxylative Mannich Addition Reactions
  163. ChemInform Abstract: Generalized Access to Fluorinated β-Keto Amino Compounds Through Asymmetric Additions of α,α-Difluoroenolates to CF3-Sulfinylimine.
  164. Metal-Free Oxidative Functionalization of C(sp3)–H Bond Adjacent to Oxygen and Radical Addition to Olefins
  165. General asymmetric synthesis of 2,2,2-trifluoro-1-(1H-indol-3- and -2-yl)ethanamines
  166. ChemInform Abstract: Metal-Free Preparation of Cycloalkyl Aryl Sulfides via Di-tert-butyl Peroxide-Promoted Oxidative C(sp3)-H Bond Thiolation of Cycloalkanes.
  167. ChemInform Abstract: Large-Scale Mannich-Type Reactions of (SS)-N-tert-Butanesulfinyl-(3,3,3)-trifluoroacetaldimine with C-Nucleophiles.
  168. Asymmetric synthesis of amino-benzothiazol derivatives by additions of 2-lithiated benzothiazoles to (S)-N-t-butylsulfinyl-ketimines
  169. A comprehensive examination of the self-disproportionation of enantiomers (SDE) of chiral amides via achiral, laboratory-routine, gravity-driven column chromatography
  170. Metal-free oxidative C(sp3)–H bond functionalization of alkanes and alkylation-initiated radical 1,2-aryl migration in α,α-diaryl allylic alcohols
  171. Asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by sequential SN2–SN2′ dialkylation of (R)-N-(benzyl)proline-derived glycine Schiff base Ni(ii) complex
  172. Introducing a new radical trifluoromethylation reagent
  173. ChemInform Abstract: Mannich-Type Addition Reactions Between Lithium Derivatives of Benzo[d]thiazoles and N-tert-Butylsulfinyl-3,3,3-trifluoroacetaldimine: Convenient Generalized Synthesis of Bis(benzothiazole)s.
  174. Ni-catalyzed asymmetric decarboxylative Mannich reaction for the synthesis of β-trifluoromethyl-β-amino ketones
  175. Asymmetric synthesis of quaternary α-fluoro-β-keto-amines via detrifluoroacetylative Mannich reactions
  176. DBU-promoted cyclization of vinyl isocyanides with ethers via the functionalization of a C(sp3)–H bond for the synthesis of isoquinolines
  177. ChemInform Abstract: Concise Asymmetric Synthesis of β-Trifluoromethylated α,β-Diamino Esters Through Addition Reactions of Glycine Esters to CF3-Sulfinylimine.
  178. ChemInform Abstract: Highly Efficient and Generalized Asymmetric Synthesis of Quaternary Stereogenic Carbon-Containing β-Amino Indanones/Indanoles via Mannich-Type Additions Between 1-Indanones and N-tert-Butanesulfinylketimines.
  179. ChemInform Abstract: Cu-Catalyzed C(sp3)-H Bond Activation Reaction for Direct Preparation of Cycloallyl Esters from Cycloalkanes and Aromatic Aldehydes.
  180. Metal-Free Oxidative C(sp 3 )–H Bond Functionalization of Alkanes and Conjugate Addition to Chromones
  181. Metal-Free Preparation of 6-Alkylthiophenanthridines via Oxidative CS and CC Bond Formation from 2-Isocyanobiphenyls and Disulfides
  182. Operationally convenient method for preparation of sulfonamides containing α,α-difluoro-β-amino carbonyl moiety
  183. ChemInform Abstract: LDA-Promoted Asymmetric Synthesis of β-Trifluoromethyl-β-amino Indanone Derivatives with Virtually Complete Stereochemical Outcome.
  184. ChemInform Abstract: Asymmetric Synthesis of β′-Amino-α,β-enones via Addition of α,β-Unsaturated Ketone-Derived Enolates to Chiral N-Phosphonyl Imines.
  185. ChemInform Abstract: Iron-Catalyzed Cross-Dehydrogenative Coupling Esterification of Unactive C(sp3)-H Bonds with Carboxylic Acids for the Synthesis of α-Acyloxy Ethers.
  186. Asymmetric synthesis of (3S,1′S)-3-(1-amino-2,2,2-trifluoroethyl)-1-(alkyl)-indolin-2-one derivatives by addition of (S)-N-t-butylsulfinyl-3,3,3-trifluoroacetaldimine to 1-(alkyl)-indolin-2-ones
  187. Large-scale Mannich-type reactions of (SS)-N-tert-butanesulfinyl-(3,3,3)-trifluoroacetaldimine with C-nucleophiles
  188. ChemInform Abstract: Concise and Scalable Asymmetric Synthesis of 5-(1-Amino-2,2,2-trifluoroethyl)thiazolo[3,2-b][1,2,4]triazoles.
  189. Generalized access to fluorinated β-keto amino compounds through asymmetric additions of α,α-difluoroenolates to CF3-sulfinylimine
  190. One-pot stereoselective synthesis of α,β-differentiated diamino esters via the sequence of aminochlorination, aziridination and intermolecular S N 2 reaction
  191. Asymmetric Friedel–Crafts Reactions of N-tert-Butylsulfinyl-3,3,3-trifluoroacetaldimines: General Access to Enantiomerically Pure Indoles Containing a 1-Amino-2,2,2-trifluoroethyl Group
  192. Metal-Free Preparation of Cycloalkyl Aryl SulfidesviaDi-tert-butyl Peroxide-Promoted Oxidative C(sp3)H Bond Thiolation of Cycloalkanes
  193. Cu-Catalyzed C(sp 3 )–H Bond Activation Reaction for Direct Preparation of Cycloallyl Esters from Cycloalkanes and Aromatic Aldehydes
  194. Iron-Catalyzed Cross-Dehydrogenative Coupling Esterification of Unactive C(sp 3 )–H Bonds with Carboxylic Acids for the Synthesis of α-Acyloxy Ethers
  195. A convenient enantioselective decarboxylative aldol reaction to access chiral α-hydroxy esters using β-keto acids
  196. ChemInform Abstract: Palladium-Catalyzed C3 Acylation of Benzofurans and Benzothiophenes with Aromatic Aldehydes by Cross-Dehydrogenative Coupling Reactions.
  197. Asymmetric synthesis of β′-amino-α,β-enones via addition of α,β-unsaturated ketone-derived enolates to chiral N-phosphonyl imines
  198. ChemInform Abstract: Asymmetric Mannich Reactions of Imidazo[2,1-b]thiazole-derived Nucleophiles with (Ss)-N-tert-Butanesulfinyl (3,3,3)-Trifluoroacetaldimine.
  199. ChemInform Abstract: Iron-Catalyzed Alkenylation of Cyclic Ethers via Decarboxylative sp3(C)-sp2(C) Coupling.
  200. Mannich-Type Addition Reactions between Lithium Derivatives of Benzo[d]thiazoles andN-tert-Butylsulfinyl-3,3,3-trifluoroacetaldimine: Convenient Generalized Synthesis of Bis(benzothiazole)s
  201. Synthesis of chiral N -phosphinyl α-imino esters and their application in asymmetric synthesis of α-amino esters by reduction
  202. NH-type of chiral Ni(ii) complexes of glycine Schiff base: design, structural evaluation, reactivity and synthetic applications
  203. Substituent-controlled preference of carbonyl group–metal coordination in d8metal complexes with non-symmetric pentadentate ligands. Structural and stereochemical aspects
  204. Concise and scalable asymmetric synthesis of 5-(1-amino-2,2,2-trifluoroethyl)thiazolo[3,2-b][1,2,4]triazoles
  205. LDA-promoted asymmetric synthesis of β-trifluoromethyl-β-amino indanone derivatives with virtually complete stereochemical outcome
  206. Highly efficient and generalized asymmetric synthesis of quaternary stereogenic carbon-containing β-amino indanones/indanoles via Mannich-type additions between 1-indanones and N-tert-butanesulfinylketimines
  207. Concise Asymmetric Synthesis of β-Trifluoromethylated α,β-Diamino Esters through Addition Reactions of Glycine Esters to CF3-Sulfinylimine
  208. Palladium-Catalyzed C3 Acylation of Benzofurans and Benzothiophenes with Aromatic Aldehydes by Cross-Dehydrogenative Coupling Reactions
  209. Iron-catalyzed alkenylation of cyclic ethers via decarboxylative sp3(C)–sp2(C) coupling
  210. Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
  211. ChemInform Abstract: Highly Diastereoselective Aminobromination of β-Methyl-β-nitrostyrenes with t-Butyl N,N-Dibromocarbamate/t-Butyl Carbamate as Bromine/Nitrogen Sources.
  212. Asymmetric C–C Bond Formation between Chiral N‐Phosphonyl Imines and a Nickel(II)‐Complexed Glycine Schiff Base Provides Efficient Synthesis of α,β‐syn‐Diamino Acid Derivatives
  213. Highly diastereoselective aminobromination of β-methyl-β-nitrostyrenes with t-butyl N,N-dibromocarbamate/t-butyl carbamate as bromine/nitrogen sources
  214. ChemInform Abstract: A Facile Organocatalyzed Michael Addition of Pyrazolines to α,β-Unsaturated Carbonyl Compounds.
  215. ChemInform Abstract: Tandem 1,5-Migration/Michael Reactions to Prepare Adducts of Pyrazolone Derivatives: Protecting Group Directed Rearrangement.
  216. ChemInform Abstract: Catalyst-Free Intramolecular Oxidative Cyclization of N-Allylbenzamides: A New Route to 2,5-Substituted Oxazoles.
  217. Approach to Vicinal t-Boc-amino Dibromides via Catalytic Aminobromination of Nitrostyrenes without Using Chromatography and Recrystallization
  218. Enantioselective synthesis of 3-hydroxy oxindoles by ytterbium-catalysed decarboxylative addition of β-ketoacids to isatins
  219. Asymmetric Mannich reactions of imidazo[2,1-b]thiazole-derived nucleophiles with (SS)-N-tert-butanesulfinyl (3,3,3)-trifluoroacetaldimine
  220. Asymmetric synthesis of α-alkenyl homoallylic primary amines via 1,2-addition of Grignard reagent to α,β-unsaturated phosphonyl imines
  221. Asymmetric Morita–Baylis–Hillman reaction of isatins with α,β-unsaturated γ-butyrolactam as the nucleophile
  222. A facile organocatalyzed Michael addition of pyrazolines to α,β-unsaturated carbonyl compounds
  223. ChemInform Abstract: Aminochlorination Reaction with N-Chlorophthalimide as a New Nitrogen/Chlorine Source Resulting in α-Amino Derivatives.
  224. Design and synthesis of quasi-diastereomeric molecules with unchanging central, regenerating axial and switchable helical chirality via cleavage and formation of Ni(II)–O and Ni(II)–N coordination bonds
  225. Cinchona Alkaloid-catalyzed Asymmetric Direct Mannich Reaction of Malononitrile to Imine for Synthesis ofβ-Amino Malononitrile
  226. ChemInform Abstract: Highly Regioselective Aminobromination of α,β-Unsaturated Nitro Compounds with Benzyl Carbamate/N-Bromosuccinimide as Nitrogen/Bromine Source.
  227. Catalyst-Free Intramolecular Oxidative Cyclization of N -Allylbenzamides: A New Route to 2,5-Substituted Oxazoles
  228. Aminochlorination reaction with N-chlorophthalimide as a new nitrogen/chlorine source resulting in α-amino derivatives
  229. ChemInform Abstract: Na3PO4-Catalyzed Aminochlorination Reaction of β-Nitrostyrenes in Water.
  230. ChemInform Abstract: Tetrabenzylhafnium as a New Organometallic Reagent for Imine Addition Resulting in α-Branched Amines.
  231. ChemInform Abstract: Potassium Carbonate Catalyzed Regioselective Aminohalogenation of β-Nitrostyrenes by Using Benzyl Carbamate/N-Chlorosuccinimide as a New Nitrogen/Chlorine Source.
  232. Na3PO4-catalyzed aminochlorination reaction of β-nitrostyrenes in water
  233. Highly regioselective aminobromination of α,β-unsaturated nitro compounds with benzyl carbamate/N-bromosuccinimide as nitrogen/bromine source
  234. Tandem 1,5-migration/Michael reactions to prepare adducts of pyrazolone derivatives: protecting group-directed rearrangement
  235. ChemInform Abstract: KOH-Catalyzed Highly Efficient Aminohalogenation of β-Nitrostyrenes with t-Butyl N,N-Dichlorocarbamate as Nitrogen/Halogen Source.
  236. ChemInform Abstract: Ligand-Free Palladium-Catalyzed Intramolecular Heck Reaction of Secondary Benzylic Bromides.
  237. ChemInform Abstract: Ultrasound-Promoted Ligand-Free Heck Reaction in Water.
  238. Potassium Carbonate Catalyzed Regioselective Aminohalogenation of β-Nitrostyrenes by Using Benzyl Carbamate/N-Chlorosuccinimide as a New Nitrogen/Chlorine Source
  239. Tetrabenzylhafnium as a New Organometallic Reagent for Imine Addition Resulting in α-Branched Amines
  240. ChemInform Abstract: A Facile Process for the Asymmetric Synthesis of β-Trifluoromethylated β-Amino Ketones via Addition of Ketone Enolates to Sulfinylimine.
  241. Self-Disproportionation of Enantiomers via Sublimation; New and Truly Green Dimension in Optical Purification
  242. Biomimetic Transamination – a Metal-Free Alternative to the Reductive Amination. Application for Generalized Preparation of Fluorine-Containing Amines and Amino Acids
  243. Ultrasound-Promoted Ligand-Free Heck Reaction in Water
  244. ChemInform Abstract: Copper-Catalyzed Aminobromination/Elimination Process: An Efficient Access to α,β-Unsaturated Vicinal Haloamino Ketones and Esters.
  245. Ligand-free palladium-catalyzed intramolecular Heck reaction of secondary benzylic bromides
  246. A facile process for the asymmetric synthesis of β-trifluoromethylated β-amino ketones via addition of ketone enolates to sulfinylimine
  247. Hydrogen-bonding self-assembly of two dimensional (2D) layer structures generating metal–organic nanotubes
  248. KOH-catalyzed highly efficient aminohalogenation of β-nitrostyrenes with t-butyl N,N-dichlorocarbamate as nitrogen/halogen source
  249. Zinc-prolinamide complex catalyzed direct asymmetric aldol reactions in the presence of water
  250. Modified thiourea used as the ligand for the synthesis of novel coordination polymers: Based on its significant conformational behavior and H-bonding preference
  251. Palladium-Catalyzed Tandem Diperoxidation/C−H Activation Resulting in Diperoxy-oxindole in Air
  252. ChemInform Abstract: Organocatalyzed Regio- and Stereoselective Diamination of Functionalized Alkenes.
  253. Molecular ladders with finite arms: The first 1D→2D polythreading with finite components based on flexibly long ligand
  254. One-Pot Highly Stereoselective Synthesis of Cyano Aziridines via the CuCl-Catalyzed Aminochlorination of α,β-Unsaturated Nitriles and Intramolecular SN2 Substitution
  255. The combination of benzamides/NCS as nitrogen/halogen sources for aminohalogenation of β-nitrostyrenes resulting in dichlorinated haloamides
  256. The Mimic of Type II Aldolases Chemistry: Asymmetric Synthesis of β-Hydroxy Ketones by Direct Aldol Reaction
  257. Organocatalyzed regio- and stereoselective diamination of functionalized alkenes
  258. The combination of TsNBr2/TsNH2 as the nitrogen/halo source for the aminobromination of β-methyl-β-nitrostyrenes catalyzed by Mn(OAc)2
  259. Copper-catalyzed aminobromination/elimination process: an efficient access to α,β-unsaturated vicinal haloamino ketones and esters
  260. ChemInform Abstract: Chiral N-Phosphonyl Imine Chemistry: Asymmetric Addition of Ketone-Derived Enolates for the Synthesis of β-Amino Ketones.
  261. Chiral N -Phosphonyl Imine Chemistry: Asymmetric Addition of Ketone-Derived Enolates for the Synthesis of β-Amino Ketones
  262. Chiral N -Phosphonyl Imine Chemistry: Asymmetric Additions of Ester Enolates for the Synthesis of β -Amino Acids
  263. Catalytic Aminohalogenation Reaction of β-Nitrostyrenes with N,N-Dichloro-p-toluenesulfonamide Resulting in Dichlorinated Haloamides with Opposite Regiochemistry to Previous Systems
  264. Catalytic Diamination of Alkenes using N,N-Dibromo-p-toluenesulfonamide as Electrophile and Nitriles as Nucleophiles
  265. Palladium-Catalyzed Aziridination of Alkenes Using N,N-Dichloro-p-toluenesulfonamide as Nitrogen Source.
  266. Palladium-catalyzed aziridination of alkenes using N,N-dichloro-p-toluenesulfonamide as nitrogen source