All Stories

  1. Engineering a Pro-Osteogenic Secretome through the Transient Silencing of the Gene Encoding Secreted Frizzled Related Protein 1

    Article • International Journal of Molecular Sciences, August 2023, MDPI AG

    Dr Jesus Delgado-Calle

  2. Osteocytes: New Kids on the Block for Cancer in Bone Therapy

    Article • Cancers, May 2023, MDPI AG

    Dr Jesus Delgado-Calle

  3. Overexpression of WNT16 Does Not Prevent Cortical Bone Loss Due to Glucocorticoid Treatment in Mice

    Article • JBMR Plus, October 2018, Wiley

    Dr Jesus Delgado-Calle

  4. MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production

    Article • The FASEB Journal, January 2018, Federation of American Societies For Experimental Biology (FASEB)

    Dr Jesus Delgado-Calle

  5. Skeletal cell YAP and TAZ combinatorially promote bone development

    Article • The FASEB Journal, January 2018, Federation of American Societies For Experimental Biology (FASEB)

    Joel Boerckel, Dr Jesus Delgado-Calle, Christopher Kegelman

  6. Osteoclasts Control Lipid Secretion to Regulate Breast Cancer Bone Metastasis

    Article • Endocrinology, March 2017, Endocrine Society

    Dr Jesus Delgado-Calle

  7. Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor

    Article • Journal of Bone and Mineral Research, October 2016, Wiley

    Dr Jesus Delgado-Calle

  8. Role and mechanism of action of sclerostin in bone

    Article • Bone, October 2016, Elsevier

    Dr Jesus Delgado-Calle

  9. Delgado-Calle et al. Osteocytes promote bone destruction in multiple myeloma

    Article • IBMS BoneKEy, August 2016, Nature

    Dr Jesus Delgado-Calle

  10. Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells

    Article • Journal of Translational Medicine, July 2016, Springer Science + Business Media

    Dr Jesus Delgado-Calle

  11. Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin

    Article • Journal of Bone and Mineral Research, June 2016, Wiley

    Dr Jesus Delgado-Calle

  12. Generation and characterization of two immortalized human osteoblastic cell lines useful for epigenetic studies

    Article • Journal of Bone and Mineral Metabolism, April 2016, Springer Science + Business Media

    Dr Jesus Delgado-Calle

  13. Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma

    Article • Cancer Research, February 2016, American Association for Cancer Research (AACR)

    Dr Jesus Delgado-Calle

  14. Osteocytes and Skeletal Pathophysiology

    Article • Current Molecular Biology Reports, October 2015, Springer Science + Business Media

    Dr Jesus Delgado-Calle

  15. Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone

    Article • Proceedings of the National Academy of Sciences, January 2015, Proceedings of the National Academy of Sciences

    Dr Jesus Delgado-Calle

  16. Role of osteocytes in multiple myeloma bone disease

    Article • Current Opinion in Supportive and Palliative Care, December 2014, Wolters Kluwer Health

    Dr Jesus Delgado-Calle

  17. Analysis of the Bone MicroRNome in Osteoporotic Fractures

    Article • Calcified Tissue International, November 2014, Springer Science + Business Media

    Dr Jesus Delgado-Calle

  18. H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

    Article • Genome Research, September 2014, Cold Spring Harbor Laboratory Press

    Dr Jesus Delgado-Calle

  19. Parathyroid Hormone Receptor Signaling Induces Bone Resorption in the Adult Skeleton by Directly Regulating theRANKLGene in Osteocytes

    Article • Endocrinology, August 2014, Endocrine Society

    Dr Jesus Delgado-Calle

  20. A Sclerostin Super-Producer Cell Line Derived from the Human Cell Line SaOS-2: A New Tool for the Study of the Molecular Mechanisms Driving Sclerostin Expression

    Article • Calcified Tissue International, June 2014, Springer Science + Business Media

    Dr Jesus Delgado-Calle

  21. The Role of DNA Methylation in Common Skeletal Disorders

    Article • March 2014, Taylor & Francis

    Dr Jesus Delgado-Calle

  22. Nitric Oxide is Involved in the Down-regulation of SOST Expression Induced by Mechanical Loading

    Article • Calcified Tissue International, December 2013, Springer Science + Business Media

    Dr Jesus Delgado-Calle

  23. Contribution of genetic and epigenetic mechanisms to Wnt pathway activity in prevalent skeletal disorders

    Article • Gene, December 2013, Elsevier

    Dr Jesus Delgado-Calle

  24. Role of BMPs in the regulation of sclerostin as revealed by an epigenetic modifier of human bone cells

    Article • Molecular and Cellular Endocrinology, April 2013, Elsevier

    Dr Jesus Delgado-Calle

  25. Mecanobiología celular y molecular del tejido óseo

    Article • Revista de Osteoporosis y Metabolismo Mineral, March 2013, Instituto de Salud Carlos III/BNCS/SciELO Espana

    Dr Jesus Delgado-Calle

  26. Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis

    Article • Arthritis & Rheumatism, December 2012, Wiley

    Dr Jesus Delgado-Calle

  27. The Role of DNA Methylation in Common Skeletal Disorders

    Article • Biology, November 2012, MDPI AG

    Dr Jesus Delgado-Calle, Jose A. Riancho

  28. Do Epigenetic Marks Govern Bone Mass and Homeostasis?

    Article • Current Genomics, April 2012, Bentham Science Publishers

    Dr Jesus Delgado-Calle, Jose A. Riancho

  29. DNA methylation contributes to the regulation of sclerostin expression in human osteocytes

    Article • Journal of Bone and Mineral Research, March 2012, Wiley

    Dr Jesus Delgado-Calle

  30. Role of DNA methylation in the regulation of the RANKL-OPG system in human bone

    Article • Epigenetics, January 2012, Taylor & Francis

    Dr Jesus Delgado-Calle

  31. Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage

    Article • Bone, October 2011, Elsevier

    Dr Jesus Delgado-Calle

  32. Mecanismos de interacción osteoblasto-osteoclasto

    Article • Reumatología Clínica, September 2011, Elsevier

    Dr Jesus Delgado-Calle, Jose A. Riancho

  33. Osteocyte Deficiency in Hip Fractures

    Article • Calcified Tissue International, August 2011, Springer Science + Business Media

    Dr Jesus Delgado-Calle