All Stories

  1. EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma
  2. S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma
  3. MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling
  4. Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data
  5. 3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness
  6. LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms
  7. The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance
  8. Var|Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data
  9. Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach
  10. Single-hit genome edition for expression of single-chain immunoglobulins by edited B cells
  11. PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma
  12. Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
  13. The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias
  14. Comprehensive characterization of the epigenetic landscape in Multiple Myeloma
  15. Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study
  16. The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5
  17. RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma
  18. Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
  19. Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma
  20. Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types
  21. Discovery of Candidate DNA Methylation Cancer Driver Genes
  22. G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death
  23. RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators
  24. Immunotherapy perspectives in the new era of B-cell editing
  25. The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of Acute Myeloid Leukemias
  26. The origin of preplasmablastic cells
  27. Multi-omics tumor profiling technologies to develop precision medicine in multiple myeloma
  28. Multi-omics tumor profiling technologies to develop precision medicine in multiple myeloma
  29. Role of Polycomb Complexes in Normal and Malignant Plasma Cells
  30. DNA Repair Expression Profiling to Identify High-Risk Cytogenetically Normal Acute Myeloid Leukemia and Define New Therapeutic Targets
  31. A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment
  32. Correction to: Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features
  33. Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features
  34. Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites
  35. Anticorps anti-CD38 dans le myélome multiple
  36. Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma
  37. Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
  38. Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple Myeloma
  39. Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact
  40. Kinome expression profiling to target new therapeutic avenues in multiple myeloma
  41. Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial
  42. The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation
  43. Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
  44. The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma
  45. Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells
  46. Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner
  47. EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation
  48. Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
  49. In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
  50. Characterization of the mutational landscape in multiple myeloma cell lines
  51. BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma
  52. PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs
  53. Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.
  54. Physiological and druggable skipping of immunoglobulin variable exons in plasma cells
  55. Rôle de EZH2 comme biomarqueur dans le traitement personnalisé du myélome multiple
  56. Tumor-associated neutrophils correlate with poor prognosis in diffuse large B-cell lymphoma patients
  57. GEP-based EpiScore predicts survival in patients with diffuse large B cell lymphoma
  58. DNMTi/HDACi induces reprogramming of myeloma cells in the direction of normal plasma cells
  59. Analysis of Global Gene Expression Profiles
  60. Loss of RASSF4 Promotes RAS-Driven Malignant Progression in MM
  61. CD24, CD27, CD36 and CD302 gene expression predict outcome in patients with multiple myeloma
  62. Automated and simplified identification of normal and abnormal plasma cells in Multiple Myeloma by flow cytometry
  63. Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion
  64. Characterization of human FCRL4-positive B cells
  65. Hypoxia favors the generation of human plasma cells
  66. Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell
  67. RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma
  68. Forced KLF4 expression increases the generation of mature plasma cells and uncovers a network linked with plasma cell stage
  69. Differential effects of lenalidomide during plasma cell differentiation
  70. RECQ helicases are deregulated in hematological malignancies in association with a prognostic value
  71. Identifying high-risk adult AML patients: epigenetic and genetic risk factors and their implications for therapy
  72. Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma
  73. Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells
  74. miRNAs in multiple myeloma – a survival relevant complex regulator of gene expression
  75. EZH2 in normal hematopoiesis and hematological malignancies
  76. Factors influencing extramedullary relapse after allogeneic transplantation for multiple myeloma
  77. Drug metabolism and clearance system in tumor cells of patients with multiple myeloma
  78. In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma
  79. Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia
  80. SNaPshot as a Valuable Option for the Identification of Mutations in Myeloma
  81. The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells
  82. DNA repair in diffuse large B-cell lymphoma: a molecular portrait
  83. Identification and characterization of new Leishmania promastigote surface antigens, LaPSA-38S and LiPSA-50S, as major immunodominant excreted/secreted components of L. amazonensis and L. infantum
  84. A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy
  85. Identification of a 20-Gene Expression-Based Risk Score as a Predictor of Clinical Outcome in Chronic Lymphocytic Leukemia Patients
  86. The Glycome of Normal and Malignant Plasma Cells
  87. DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine
  88. DNA repair pathways in human multiple myeloma
  89. Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors
  90. Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma
  91. Inhibition of DEPDC1A, a Bad Prognostic Marker in Multiple Myeloma, Delays Growth and Induces Mature Plasma Cell Markers in Malignant Plasma Cells
  92. Kruppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma
  93. STEAP1 is overexpressed in cancers: A promising therapeutic target
  94. Gene expression-based risk score in diffuse large B-cell lymphoma
  95. Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?
  96. Growth Factors in Multiple Myeloma
  97. Development of Gene Expression-Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation Inhibitors
  98. Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients
  99. Identification of Pluripotent and Adult Stem Cell Genes Unrelated to Cell Cycle and Associated with Poor Prognosis in Multiple Myeloma
  100. Clinical and prognostic role of annexin A2 in multiple myeloma
  101. Critical role of the NOTCH ligand JAG2 in self-renewal of myeloma cells
  102. New prognostic markers, determined using gene expression analyses, reveal two distinct subtypes of chronic myelomonocytic leukaemia patients
  103. Efficient transduction of healthy and malignant plasma cells by lentiviral vectors pseudotyped with measles virus glycoproteins
  104. Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma
  105. SULFs in human neoplasia: implication as progression and prognosis factors
  106. The role of fluorescence in situ hybridization and gene expression profiling in myeloma risk stratification
  107. A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines
  108. MYEOV is a prognostic factor in multiple myeloma
  109. Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration
  110. Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma
  111. Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays
  112. Abstract 124: Involvement of the notch pathway in the clonogenicity of human multiple myeloma cell lines
  113. NPM1 is overexpressed in hyperdiploid multiple myeloma due to a gain of chromosome 5 but is not delocalized to the cytoplasm
  114. Atacicept in relapsed/refractory multiple myeloma or active Waldenström's macroglobulinemia: a phase I study
  115. Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis
  116. APRIL and TACI interact with syndecan-1 on the surface of multiple myeloma cells to form an essential survival loop
  117. Embryonic stem cell markers expression in cancers
  118. Induction of angiogenesis by normal and malignant plasma cells
  119. APRIL is overexpressed in cancer: link with tumor progression
  120. The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor
  121. MMSET is overexpressed in cancers: Link with tumor aggressiveness
  122. Cytokine Pathways in Myeloma Growth and Survival
  123. Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma
  124. CD200: A putative therapeutic target in cancer
  125. Input of DNA Microarrays to Identify Novel Mechanisms in Multiple Myeloma Biology and Therapeutic Applications
  126. Targeting NF-κB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth
  127. TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines
  128. CD200 is a new prognostic factor in multiple myeloma
  129. P20. TACI-signalling in multiple myeloma – From the identification as potential therapeutic target by gene expression analysis and functional testing to clinical trials
  130. P43. ErbB-signalling in multiple myeloma – From the identification as potential therapeutic target by gene expression analysis and functional testing to clinical trials
  131. P21. A molecular classification of multiple myeloma (MM) based on gene expression profiling and fluorescence in situ hybridisation as independent prognostic factor for event free survival (EFS)
  132. Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma
  133. Microarray-based understanding of normal and malignant plasma cells
  134. Lymphocytes of dogs immunised with purified excreted-secreted antigens of Leishmania infantum co-incubated with Leishmania infected macrophages produce IFN gamma resulting in nitric oxide-mediated amastigote apoptosis
  135. The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature
  136. Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells
  137. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
  138. Survival and Proliferation Factors of Normal and Malignant Plasma Cells