All Stories

  1. Dynamics in Redox-Active Molecules Following Ischemic Preconditioning in the Brain

    Article • Neurology International, May 2024, MDPI AG

    Professor jan Lehotsky

  2. Analysis of Cdx2 VDR gene polymorphism rs11568820 in association with multiple sclerosis in Slovaks

    Article • Neurological Research, August 2023, Taylor & Francis

    Professor jan Lehotsky

  3. Hippocampal metabolic recovery as a manifestation of the protective effect of ischemic preconditioning in rats

    Article • Neurochemistry International, November 2022, Elsevier

    Professor jan Lehotsky

  4. Metabolomic Recovery as a Result of Ischemic Preconditioning Was More Pronounced in Hippocampus than in Cortex That Appeared More Sensitive to Metabolomic Blood Components

    Article • Metabolites, August 2021, MDPI AG

    Professor jan Lehotsky

  5. The Ability to Normalise Energy Metabolism in Advanced COVID-19 Disease Seems to Be One of the Key Factors Determining the Disease Progression—A Metabolomic NMR Study on Blood Plasma

    Article • Applied Sciences, May 2021, MDPI AG

    Professor jan Lehotsky

  6. Time‐related metabolomics study in the rat plasma after global cerebral ischemia and reperfusion: Effect of ischemic preconditioning

    Article • IUBMB Life, July 2020, Wiley

    Professor jan Lehotsky

  7. Metabolic and histopathological changes in the brain and plasma of rats exposed to fractionated whole-brain irradiation

    Article • Brain Research, April 2019, Elsevier

    Professor jan Lehotsky

  8. Histone Hyperacetylation as a Response to Global Brain Ischemia Associated with Hyperhomocysteinemia in Rats

    Article • International Journal of Molecular Sciences, October 2018, MDPI AG

    Professor jan Lehotsky

  9. Association of Induced Hyperhomocysteinemia with Alzheimer’s Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury

    Article • Neurochemical Research, July 2018, Springer Science + Business Media

    Professor jan Lehotsky

  10. The increased serum level of sRAGE is associated with multiple sclerosis but not with disability progression

    Article • Neurological Sciences and Neurophysiology, June 2018, AVES Publishing Co.

    Professor jan Lehotsky

  11. NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia

    Article • Journal of Physiology and Biochemistry, May 2018, Springer Science + Business Media

    Professor jan Lehotsky

  12. The HLA-DRB1 and HLA-DQB1 alleles are associated with multiple sclerosis disability progression in Slovak population

    Article • Neurological Research, April 2018, Taylor & Francis

    Professor jan Lehotsky

  13. Effects of fractionated whole-brain irradiation on cellular composition and cognitive function in the rat brain

    Article • International Journal of Radiation Biology, January 2018, Taylor & Francis

    Professor jan Lehotsky

  14. Effect of whole-brain irradiation on the specific brain regions in a rat model: Metabolic and histopathological changes

    Article • NeuroToxicology, May 2017, Elsevier

    Professor jan Lehotsky

  15. Proteomic analysis of mitochondrial proteins in the guinea pig heart following long-term normobaric hyperoxia

    Article • Molecular and Cellular Biochemistry, April 2017, Springer Science + Business Media

    Professor jan Lehotsky

  16. Redox balance in hyperhomocysteinemic conditions

    Article • Cellular and Molecular Neurobiology, February 2017, Springer Science + Business Media

    Professor jan Lehotsky

  17. The age at onset in Multiple Sclerosis is associated with patient’s prognosis

    Article • Bratislava Medical Journal, January 2017, AEPress, s.r.o.

    Professor jan Lehotsky

  18. Role of Homocysteine in the Ischemic Stroke and Development of Ischemic Tolerance

    Article • Frontiers in Neuroscience, November 2016, Frontiers

    Professor jan Lehotsky

  19. The Molecular and Cellular Effect of Homocysteine Metabolism Imbalance on Human Health

    Article • International Journal of Molecular Sciences, October 2016, MDPI AG

    Professor jan Lehotsky

  20. Influence of hyperhomocysteinemia on ischemic stroke

    Article • October 2016, IntechOpen

    Professor jan Lehotsky

  21. genetic factors of SM

    Article • September 2016, IntechOpen

    Professor jan Lehotsky

  22. Association of EGF, IGFBP-3 and TP53 Gene Polymorphisms with Major Depressive Disorder in Slovak Population

    Article • Central European Journal of Public Health, September 2016, National Institute of Public Health

    Professor jan Lehotsky

  23. ApaI, BsmI and TaqIVDRgene polymorphisms in association with multiple sclerosis in Slovaks

    Article • Neurological Research, June 2016, Taylor & Francis

    Professor jan Lehotsky

  24. The Effect of Aging on Mitochondrial Complex I and the Extent of Oxidative Stress in the Rat Brain Cortex

    Article • Neurochemical Research, May 2016, Springer Science + Business Media

    Professor jan Lehotsky

  25. The association of HLA-DRB1 and HLA-DQB1 alleles with genetic susceptibility to multiple sclerosis in the Slovak population

    Article • Neurological Research, December 2015, Taylor & Francis

    Professor jan Lehotsky

  26. Effects of mild hyperhomocysteinemia on electron transport chain complexes, oxidative stress, and protein expression in rat cardiac mitochondria

    Article • Molecular and Cellular Biochemistry, October 2015, Springer Science + Business Media

    Professor jan Lehotsky

  27. Radiation impact on hippocampal region

    Article • Klinicka onkologie, June 2015, Ambit Media, a.s.

    Professor jan Lehotsky

  28. Genetic variants in interleukin 7 receptor α chain (IL-7Ra) are associated with multiple sclerosis risk and disability progression in Central European Slovak population

    Article • Journal of Neuroimmunology, May 2015, Elsevier

    Professor jan Lehotsky

  29. Doublecortin and Microglial Markers in the Rat Brain Following Fractionated Irradiation

    Article • Neurochemical Research, December 2014, Springer Science + Business Media

    Professor jan Lehotsky

  30. Vitamin D receptor polymorphism association with the risk of multiple sclerosis

    Article • Neurological Research, November 2014, Taylor & Francis

    Professor jan Lehotsky

  31. Mechanisms Involved in the Ischemic Tolerance in Brain: Effect of the Homocysteine

    Article • Cellular and Molecular Neurobiology, September 2014, Springer Science + Business Media

    Professor jan Lehotsky

  32. Rostral migratory stream influenced by radiation

    Article • Acta Histochemica, January 2014, Elsevier

    Professor jan Lehotsky

  33. Aging and redox products

    Article • General Physiology and Biophysics, January 2014, AEPress, s.r.o.

    Professor jan Lehotsky

  34. Ionizing radiation impact to proliferative activity

    Article • Klinicka onkologie, October 2013, Ambit Media, a.s.

    Professor jan Lehotsky

  35. Fractionated irradiation-induced altered spatio-temporal cell distribution in the rat forebrain

    Article • Acta Histochemica, May 2013, Elsevier

    Professor jan Lehotsky

  36. Long-term alterations of cell population in the adult rat forebrain following the exposure to fractionated doses of ionizing radiation

    Article • General Physiology and Biophysics, January 2013, AEPress, s.r.o.

    Professor jan Lehotsky

  37. Intracellular Signaling MAPK Pathway After Cerebral Ischemia–Reperfusion Injury

    Article • Neurochemical Research, March 2012, Springer Science + Business Media

    Professor jan Lehotsky

  38. Mechanism of ischemic damage

    Article • March 2012, IntechOpen

    Professor jan Lehotsky

  39. Analysis of genetic polymorphisms of brain-derived neurotrophic factor and methylenetetrahydrofolate reductase in depressed patients in a Slovak (Caucasian) population

    Article • General Physiology and Biophysics, January 2012, AEPress, s.r.o.

    Professor jan Lehotsky

  40. Effect of normobaric oxygen treatment on oxidative stress and enzyme activities in guinea pig heart

    Article • General Physiology and Biophysics, January 2012, AEPress, s.r.o.

    Professor jan Lehotsky

  41. Embryonic nucleogenesis

    Article • Biologia, January 2012, De Gruyter

    Professor jan Lehotsky

  42. Effect of Long-Term Normobaric Hyperoxia on Oxidative Stress in Mitochondria of the Guinea Pig Brain

    Article • Neurochemical Research, April 2011, Springer Science + Business Media

    Professor jan Lehotsky

  43. Response of secretory pathways Ca2+ ATPase gene expression to hyperhomocysteinemia and/or ischemic preconditioning in rat cerebral cortex and hippocampus

    Article • General Physiology and Biophysics, January 2011, AEPress, s.r.o.

    Professor jan Lehotsky

  44. Embryonal nucleogenesis and role of RNA polymerase II trnascriprion

    Article • Biologia, January 2010, De Gruyter

    Professor jan Lehotsky

  45. Ischemic Tolerance: The Mechanisms of Neuroprotective Strategy

    Article • The Anatomical Record, December 2009, Wiley

    Professor jan Lehotsky

  46. Effects of long-term oxygen treatment on α-ketoglutarate dehydrogenase activity and oxidative modifications in mitochondria of the guinea pig heart

    Article • European Journal of Medical Research, December 2009, Springer Science + Business Media

    Professor jan Lehotsky

  47. Alterations Induced by Ischemic Preconditioning on Secretory Pathways Ca2+-ATPase (SPCA) Gene Expression and Oxidative Damage After Global Cerebral Ischemia/Reperfusion in Rats

    Article • Cellular and Molecular Neurobiology, March 2009, Springer Science + Business Media

    Professor jan Lehotsky

  48. Molecular Mechanisms Leading to Neuroprotection/Ischemic Tolerance: Effect of Preconditioning on the Stress Reaction of Endoplasmic Reticulum

    Article • Cellular and Molecular Neurobiology, March 2009, Springer Science + Business Media

    Professor jan Lehotsky

  49. Molecular Analysis of Endoplasmic Reticulum Stress Response After Global Forebrain Ischemia/Reperfusion in Rats: Effect of Neuroprotectant Simvastatin

    Article • Cellular and Molecular Neurobiology, September 2008, Springer Science + Business Media

    Professor jan Lehotsky

  50. Do Statins Influence the Activity of c-fos Gene Following Transient Forebrain Ischaemia in the Adult Rat Hippocampus?

    Article • Acta Veterinaria Brno, January 2008, University of Veterinary and Pharmaceutical Sciences

    Professor jan Lehotsky

  51. Time Course of Peripheral Oxidative Stress as Consequence of Global Ischaemic Brain Injury in Rats

    Article • Cellular and Molecular Neurobiology, December 2007, Springer Science + Business Media

    Professor jan Lehotsky

  52. Oxidative modifications of cardiac mitochondria and inhibition of cytochromecoxidase activity by 4-hydroxynonenal

    Article • Redox Report, October 2007, Taylor & Francis

    Professor jan Lehotsky

  53. Effect of aging on the expression of intracellular Ca2+ transport proteins in a rat heart

    Article • Molecular and Cellular Biochemistry, February 2007, Springer Science + Business Media

    Professor jan Lehotsky

  54. Distribution of Secretory Pathway Ca 2+ ATPase (SPCA1) in Neuronal and Glial Cell Cultures

    Article • Cellular and Molecular Neurobiology, June 2006, Springer Science + Business Media

    Professor jan Lehotsky

  55. Biochemical and Clinical Improvement of Cytotoxic State by Amantadine Sulphate

    Article • Cellular and Molecular Neurobiology, May 2006, Springer Science + Business Media

    Professor jan Lehotsky

  56. Impact of Ginkgo Biloba Extract EGb 761 on Ischemia/Reperfusion – Induced Oxidative Stress Products Formation in Rat Forebrain

    Article • Cellular and Molecular Neurobiology, April 2006, Springer Science + Business Media

    Professor jan Lehotsky

  57. Article • Molecular and Cellular Biochemistry, January 2003, Springer Science + Business Media

    Professor jan Lehotsky

  58. The role of plasma membrane CA2+ Pumps (PMCAs) in pathologies of mammalian cells

    Article • Frontiers in Bioscience, January 2002, Frontiers in Bioscience

    Professor jan Lehotsky

  59. Role of PMCA in cells

    Article • Frontiers in Bioscience, January 2002, Frontiers in Bioscience

    Professor jan Lehotsky

  60. Article • Molecular and Cellular Biochemistry, January 2002, Springer Science + Business Media

    Professor jan Lehotsky

  61. Iron-induced lipid peroxidation and protein modification in endoplasmic reticulum membranes. Protection by stobadine

    Article • The International Journal of Biochemistry & Cell Biology, May 2000, Elsevier

    Professor jan Lehotsky

  62. Article • Neurochemical Research, January 2000, Springer Science + Business Media

    Professor jan Lehotsky

  63. Membrane ion transport systems during oxidative stress in rodent brain: Protective effect of stobadine and other antioxidants

    Article • Life Sciences, October 1999, Elsevier

    Professor jan Lehotsky

  64. Distribution of plasma membrane Ca2+ pump (PMCA) isoforms in the gerbil brain: effect of ischemia-reperfusion injury

    Article • Neurochemistry International, September 1999, Elsevier

    Professor jan Lehotsky

  65. Fe2+-induced inhibition of gerbil forebrain microsomal Ca2+-ATPase: Effect of stobadine, glutathione and combination of both antioxidants

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, March 1998, Elsevier

    Professor jan Lehotsky

  66. LPO products to inhibit Ca stores function

    Article • IUBMB Life, April 1997, Wiley

    Professor jan Lehotsky

  67. Ischemic damage to Ca stores

    Article • January 1997, Springer Science + Business Media

    Professor jan Lehotsky

  68. Synaptosomal Na, K-ATPase during forebrain ischemia in Mongolian gerbils

    Article • Molecular and Chemical Neuropathology, September 1996, Springer Science + Business Media

    Professor jan Lehotsky

  69. Change in fluidity of brain endoplasmic reticulum membranes by oxygen free radicals: A protective effect of stobadine, α-tocopherol acetate, and butylated hydroxytoluene

    Article • Neurochemical Research, July 1995, Springer Science + Business Media

    Professor jan Lehotsky

  70. Role of PMCA in brain

    Article • Molecular and Chemical Neuropathology, June 1995, Springer Science + Business Media

    Professor jan Lehotsky

  71. Alteration in Rabbit Brain Endoplasmic Reticulum Ca2+ Transport by Free Oxygen Radicals in Vitro

    Article • Biochemical and Biophysical Research Communications, February 1994, Elsevier

    Professor jan Lehotsky

  72. Stimulation of the catalytic cycle of the Ca2+ pump of porcine plasma-membranes by negatively charged phospholipids

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, March 1992, Elsevier

    Professor jan Lehotsky

  73. Conformational changes of (Ca2+-Mg2+)-ATPase of erythrocyte plasma membrane caused by calmodulin and phosphatidylserine as revealed by circular dichroism and fluorescence studies

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, November 1989, Elsevier

    Professor jan Lehotsky

  74. EGb function in biological systems

    Article • Springer Science + Business Media

    Professor jan Lehotsky