All Stories

  1. Impact of PPP1R1A Knockdown on the Proteomic Landscape of INS-1 Cells: A Focus on Significant Modulated Pathways

    Article • Journal of Proteome Research, December 2025, American Chemical Society (ACS)

    Jalal Taneera

  2. Vitamin D augments insulin secretion via calcium influx and upregulation of voltage calcium channels: Findings from INS-1 cells and human islets

    Article • Molecular and Cellular Endocrinology, April 2025, Elsevier

    Jalal Taneera

  3. The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells

    Article • Cells, January 2025, MDPI AG

    Jalal Taneera

  4. Unraveling the Interplay of Autophagy Genes and KLF3/KLF8 in Colorectal Cancer Metastasis: A Bioinformatics and cellular Exploration

    Article • F1000Research, July 2024, Faculty of 1000, Ltd.

    Jalal Taneera

  5. Investigating the Impact of IL6 on Insulin Secretion: Evidence from INS-1 Cells, Human Pancreatic Islets, and Serum Analysis

    Article • Cells, April 2024, MDPI AG

    Jalal Taneera

  6. Preservation of β-Cells as a Therapeutic Strategy for Diabetes

    Article • Hormone and Metabolic Research, February 2024, Thieme Publishing Group

    Jalal Taneera

  7. Targeting Hypoxia-Inducible Factor-1 (HIF-1) in Cancer: Emerging Therapeutic Strategies and Pathway Regulation

    Article • Pharmaceuticals, February 2024, MDPI AG

    Jalal Taneera

  8. β-Thalassemia and Diabetes Mellitus: Current State and Future Directions

    Article • Hormone and Metabolic Research, October 2023, Thieme Publishing Group

    Jalal Taneera

  9. Disrupting of family with sequence similarity 105, member A (Fam105a) deteriorates pancreatic β-cell physiology and insulin secretion in INS-1 cells

    Article • Molecular and Cellular Endocrinology, August 2023, Elsevier

    Jalal Taneera

  10. Dual Role of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 in Inflammasome and Pancreatic β-Cell Function

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Professor Khaled M. Aboshanab, Jalal Taneera

  11. Expression Silencing of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 Conferred Its Role in Pancreatic β-Cell Physiology and Insulin Secretion

    Article • Metabolites, February 2023, MDPI AG

    Professor Khaled M. Aboshanab, Jalal Taneera

  12. GDF15plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets

    Article • Experimental Biology and Medicine, February 2023, Frontiers

    Jalal Taneera

  13. Reduced Retinoic Acid Receptor Beta (Rarβ) Affects Pancreatic β-Cell Physiology

    Article • Biology, July 2022, MDPI AG

    Jalal Taneera

  14. Profiling Levels of Serum microRNAs and Soluble ACE2 in COVID-19 Patients

    Article • Life, April 2022, MDPI AG

    Jalal Taneera

  15. Carnosic Acid Protects INS-1 β-Cells against Streptozotocin-Induced Damage by Inhibiting Apoptosis and Improving Insulin Secretion and Glucose Uptake

    Article • Molecules, March 2022, MDPI AG

    Jalal Taneera

  16. EXOC6 (Exocyst Complex Component 6) Is Associated with the Risk of Type 2 Diabetes and Pancreatic β-Cell Dysfunction

    Article • Biology, March 2022, MDPI AG

    Jalal Taneera

  17. Heme Oxygenase-1 (HMOX-1) and inhibitor of differentiation proteins (ID1, ID3) are key response mechanisms against iron-overload in pancreatic β-cells

    Article • Molecular and Cellular Endocrinology, December 2021, Elsevier

    Jalal Taneera

  18. The Coffee Diterpene, Kahweol, Ameliorates Pancreatic β-Cell Function in Streptozotocin (STZ)-Treated Rat INS-1 Cells through NF-kB and p-AKT/Bcl-2 Pathways

    Article • Molecules, August 2021, MDPI AG

    Jalal Taneera

  19. Expression of SARS-CoV-2 receptor “ACE2” in human pancreatic β cells: to be or not to be!

    Article • Islets, July 2021, Taylor & Francis

    Jalal Taneera

  20. Carnosic Acid Induces Apoptosis and Inhibits Akt/mTOR Signaling in Human Gastric Cancer Cell Lines

    Article • Pharmaceuticals, March 2021, MDPI AG

    Jalal Taneera

  21. Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors

    Article • Biology, August 2020, MDPI AG

    Jalal Taneera

  22. Genetic Variants of the PLCXD3 Gene Are Associated with Risk of Metabolic Syndrome in the Emirati Population

    Article • Genes, June 2020, MDPI AG

    Jalal Taneera

  23. An Integrative Phenotype–Genotype Approach Using Phenotypic Characteristics from the UAE National Diabetes Study Identifies HSD17B12 as a Candidate Gene for Obesity and Type 2 Diabetes

    Article • Genes, April 2020, MDPI AG

    Jalal Taneera

  24. Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells

    Article • Biology, April 2020, MDPI AG

    Jalal Taneera

  25. Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction

    Article • Molecular and Cellular Endocrinology, January 2020, Elsevier

    Jalal Taneera

  26. Prediabetes and diabetes prevalence and risk factors comparison between ethnic groups in the United Arab Emirates

    Article • Scientific Reports, November 2019, Springer Science + Business Media

    Jalal Taneera

  27. Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells

    Article • Frontiers in Endocrinology, November 2019, Frontiers

    Jalal Taneera

  28. Potential role of hypothalamic microRNAs in regulation of FOS and FTO expression in response to hypoglycemia

    Article • The Journal of Physiological Sciences, November 2019, Elsevier

    Jalal Taneera

  29. Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell ...

    Article • Experimental and Clinical Endocrinology & Diabetes, October 2019, Thieme Publishing Group

    Jalal Taneera

  30. GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells

    Article • Gene, October 2019, Elsevier

    Jalal Taneera

  31. Dimethyloxalylglycine (DMOG) and the Caspase Inhibitor “Ac-LETD-CHO” Protect Neuronal ND7/23 Cells of Gluocotoxicity

    Article • Experimental and Clinical Endocrinology & Diabetes, June 2019, Thieme Publishing Group

    Jalal Taneera

  32. The Case for an Estrogen-iron Axis in Health and Disease

    Article • Experimental and Clinical Endocrinology & Diabetes, April 2019, Thieme Publishing Group

    Jalal Taneera

  33. RORB and RORC associate with human islet dysfunction and inhibit insulin secretion in INS-1 cells

    Article • Islets, January 2019, Taylor & Francis

    Jalal Taneera, Professor Mawieh Hamad

  34. Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells

    Article • Molecular and Cellular Endocrinology, September 2018, Elsevier

    Jalal Taneera

  35. Maturity-Onset Diabetes of the Young: An Overview with Focus on the Middle East

    Article • Current Molecular Medicine, March 2018, Bentham Science Publishers

    Maha Saber-Ayad, Jalal Taneera

  36. Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia

    Article • Human Molecular Genetics, December 2014, Oxford University Press (OUP)

    Jalal Taneera

  37. Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

    Article • Proceedings of the National Academy of Sciences, September 2014, Proceedings of the National Academy of Sciences

    Jalal Taneera

  38. A Central Role for GRB10 in Regulation of Islet Function in Man

    Article • PLoS Genetics, April 2014, PLOS

    Jari Lahti, Jalal Taneera

  39. Downregulation of Type II Diabetes Mellitus and Maturity Onset Diabetes of Young Pathways in Human Pancreatic Islets from Hyperglycemic Donors

    Article • Journal of Diabetes Research, January 2014, Wiley

    Jalal Taneera

  40. Autoimmunity against INS-IGF2 Protein Expressed in Human Pancreatic Islets

    Article • Journal of Biological Chemistry, August 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jalal Taneera

  41. Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes

    Article • Molecular and Cellular Endocrinology, August 2013, Elsevier

    Jalal Taneera

  42. Effects of Common Genetic Variants Associated With Type 2 Diabetes and Glycemic Traits on α- and β-Cell Function and Insulin Action in Humans

    Article • Diabetes, April 2013, American Diabetes Association

    Jalal Taneera

  43. Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes

    Article • Molecular and Cellular Endocrinology, November 2012, Elsevier

    Jalal Taneera

  44. Secreted Frizzled-Related Protein 4 Reduces Insulin Secretion and Is Overexpressed in Type 2 Diabetes

    Article • Cell Metabolism, November 2012, Elsevier

    Jalal Taneera

  45. A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets

    Article • Cell Metabolism, July 2012, Elsevier

    Jalal Taneera

  46. Erratum

    Article • Diabetes, May 2012, American Diabetes Association

    Jalal Taneera

  47. γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

    Article • Diabetologia, April 2012, Springer Science + Business Media

    Jalal Taneera

  48. Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes

    Article • European Journal of Endocrinology, October 2011, Bioscientifica

    Jalal Taneera, Marloes Dekker Nitert

  49. A common variant upstream of the PAX6 gene influences islet function in man

    Article • Diabetologia, September 2011, Springer Science + Business Media

    Jalal Taneera

  50. Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

    Article • Diabetes, August 2011, American Diabetes Association

    Professor Thomas Munzel or Muenzel, Jalal Taneera

  51. Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

    Article • Diabetes, August 2011, American Diabetes Association

    Jalal Taneera

  52. A Common Variant in TFB1M Is Associated with Reduced Insulin Secretion and Increased Future Risk of Type 2 Diabetes

    Article • Cell Metabolism, January 2011, Elsevier

    Jalal Taneera, Marloes Dekker Nitert

  53. Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

    Article • Diabetologia, November 2010, Springer Science + Business Media

    Jalal Taneera, Marloes Dekker Nitert

  54. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

    Article • Nature Genetics, January 2010, Springer Science + Business Media

    Jalal Taneera

  55. Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCα and PKCδ

    Article • Diabetologia, December 2009, Springer Science + Business Media

    Dr Stefan Amisten, Jalal Taneera

  56. Tight Coupling between Glucose and Mitochondrial Metabolism in Clonal β-Cells Is Required for Robust Insulin Secretion

    Article • Journal of Biological Chemistry, September 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jalal Taneera

  57. A Variant in the KCNQ1 Gene Predicts Future Type 2 Diabetes and Mediates Impaired Insulin Secretion

    Article • Diabetes, July 2009, American Diabetes Association

    Jalal Taneera

  58. Long‐term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke

    Article • Glia, December 2008, Wiley

    Professor Zaal Kokaia, Jalal Taneera

  59. Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic  -Cell Fate

    Article • Diabetes, January 2006, American Diabetes Association

    Jalal Taneera

  60. Bone marrow–derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation

    Article • Nature Medicine, April 2004, Springer Science + Business Media

    Jalal Taneera

  61. Letters to the Editor

    Article • Journal of Hepatology, August 2000, Elsevier

    Jalal Taneera