All Stories

  1. Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B

    Article • Immunology, June 2015, Wiley

    Dr Jacques A NUNES

  2. Flow cytometric analysis of intracellular phosphoproteins in human monocytes

    Article • Cytometry Part B Clinical Cytometry, April 2015, Wiley

    Dr Jacques A NUNES

  3. CD28 deletion improves obesity-induced liver steatosis but increases adiposity in mice

    Article • International Journal of Obesity, March 2015, Nature

    Dr Jacques A NUNES

  4. In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation

    Article • Cellular and Molecular Life Sciences, March 2015, Springer Science + Business Media

    Dr Jacques A NUNES

  5. Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML)

    Article • Leukemia, September 2014, Nature

    Dr Jacques A NUNES

  6. Dok1 and Dok2 proteins regulate natural killer cell development and function

    Article • The EMBO Journal, June 2014, EMBO

    Dr Jacques A NUNES

  7. Constitutive AKT activation in follicular lymphoma

    Article • BMC Cancer, January 2014, Springer Science + Business Media

    Dr Jacques A NUNES

  8. ADAPted secretion of cytokines in NK cells

    Article • Nature Immunology, October 2013, Nature

    Dr Jacques A NUNES

  9. O79 Rôle du CD28 dans le développement de l’état inflammatoire et des complications métaboliques associés à l’obésité

    Article • Diabetes & Metabolism, March 2013, Elsevier

    Dr Jacques A NUNES

  10. An Emerging Role for PI5P in T Cell Biology

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr Jacques A NUNES

  11. HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells

    Article • Blood, October 2012, American Society of Hematology

    Dr Jacques A NUNES

  12. Analysis of Cellular Signaling Events by Flow Cytometry

    Article • June 2012, IntechOpen

    Dr Jacques A NUNES

  13. Hepatitis C virus fails to activate NF-kappaB signaling in plasmacytoid dendritic cells

    Article • Retrovirology, January 2012, Springer Science + Business Media

    Dr Jacques A NUNES

  14. CD277 an Immune Regulator of T Cell Function and Tumor Cell Recognition

    Article • November 2011, IntechOpen

    Dr Jacques A NUNES, Professor Daniele Saverino

  15. Hepatitis C Virus Fails To Activate NF- B Signaling in Plasmacytoid Dendritic Cells

    Article • Journal of Virology, November 2011, ASM Journals

    Dr Jacques A NUNES

  16. Differential role for CD277 as a co-regulator of the immune signal in T and NK cells

    Article • European Journal of Immunology, November 2011, Wiley

    Dr Jacques A NUNES

  17. Rôle de CTLA-4 dans la cosignalisation négative du système immunitaire

    Article • médecine/sciences, October 2011, EDP Sciences

    Dr Jacques A NUNES

  18. PD-L2 is expressed on activated human T cells and regulates their function

    Article • Molecular Immunology, September 2011, Elsevier

    Dr Jacques A NUNES

  19. Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

    Article • Nature Medicine, May 2011, Nature

    Dr Jacques A NUNES

  20. PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1

    Article • International Immunology, June 2010, Oxford University Press (OUP)

    Dr Jacques A NUNES

  21. Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways

    Article • FEBS Letters, April 2010, Wiley

    Dr Jacques A NUNES

  22. Highjacking of PI3K/AKT signaling pathway by Hepatitis C virus in TLR9-activated human plasmacytoid dendritic cells

    Article • Retrovirology, January 2010, Springer Science + Business Media

    Dr Jacques A NUNES

  23. Analysis of Signaling Events by Dynamic Phosphoflow Cytometry

    Article • Science Signaling, August 2009, American Association for the Advancement of Science

    Dr Jacques A NUNES

  24. Dok-4 Is a Novel Negative Regulator of T Cell Activation

    Article • The Journal of Immunology, June 2009, The American Association of Immunologists

    Dr Jacques A NUNES

  25. Cutting Edge: Dok-1 and Dok-2 Adaptor Molecules Are Regulated by Phosphatidylinositol 5-Phosphate Production in T Cells

    Article • The Journal of Immunology, April 2009, The American Association of Immunologists

    Dr Jacques A NUNES

  26. Tyrosine-protein kinase Tec

    Article • Targeted Protein Database, November 2008, Current Biodata

    Dr Jacques A NUNES

  27. Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation

    Article • Nature Methods, July 2008, Nature

    Dr Jacques A NUNES

  28. ICOS Ligation Recruits the p50  PI3K Regulatory Subunit to the Immunological Synapse

    Article • The Journal of Immunology, July 2008, The American Association of Immunologists

    Dr Jacques A NUNES

  29. Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA

    Article • Gene Therapy, March 2008, Nature

    Dr Jacques A NUNES

  30. Role for the CD28 Molecule in the Control of Coxiella burnetii Infection

    Article • Infection and Immunity, March 2006, ASM Journals

    Dr Jacques A NUNES

  31. Natural Killer Cell Signaling Pathways

    Article • Science, November 2004, American Association for the Advancement of Science

    Dr Jacques A NUNES

  32. The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

    Article • The Journal of Experimental Medicine, September 2004, Rockefeller University Press

    Dr Jacques A NUNES

  33. Tec Kinase Migrates to the T Cell-APC Interface Independently of Its Pleckstrin Homology Domain

    Article • The Journal of Immunology, July 2004, The American Association of Immunologists

    Dr Jacques A NUNES

  34. The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule

    Article • European Journal of Immunology, July 2004, Wiley

    Dr Jacques A NUNES

  35. Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase

    Article • Oncogene, December 2003, Nature

    Dr Jacques A NUNES

  36. IFN-  Skews Monocyte Differentiation into Toll-Like Receptor 7-Expressing Dendritic Cells with Potent Functional Activities

    Article • The Journal of Immunology, September 2003, The American Association of Immunologists

    Dr Jacques A NUNES

  37. DOK4 and DOK5: new dok-related genes expressed in human T cells

    Article • Genes & Immunity, January 2003, Nature

    Dr Jacques A NUNES

  38. Novel CD28-Responsive Enhancer Activated by CREB/ATF and AP-1 Families in the Human Interleukin-2 Receptor α-Chain Locus

    Article • Molecular and Cellular Biology, July 2001, ASM Journals

    Dr Jacques A NUNES

  39. Role of Tec kinase in nuclear factor of activated T cells signaling

    Article • International Immunology, November 2000, Oxford University Press (OUP)

    Dr Jacques A NUNES

  40. Tec Kinases

    Article • Immunity, April 2000, Elsevier

    Dr Jacques A NUNES

  41. Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling

    Article • Immunity, April 1999, Elsevier

    Dr Jacques A NUNES

  42. Analysis of immunoreceptor tyrosine-based activation motif (ITAM) binding to ZAP-70 by surface plasmon resonance

    Article • European Journal of Immunology, November 1997, Wiley

    Dr Jacques A NUNES

  43. Signal Transduction by CD28 Costimulatory Receptor on T Cells: B7-1 and B7-2 REGULATION OF TYROSINE KINASE ADAPTOR MOLECULES

    Article • Journal of Biological Chemistry, January 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jacques A NUNES

  44. CD28 signal transduction pathways. A comparison of B7-1 and B7-2 regulation of the MAP kinases: ERK2 and Jun kinases

    Article • Molecular Immunology, January 1996, Elsevier

    Dr Jacques A NUNES, Dr James R Woodgett

  45. The Regulation and Function of p21Ras in T Cell Activation and Growth

    Article • January 1995, Springer Science + Business Media

    Dr Jacques A NUNES

  46. Regions of the CD8 Molecule Involved in the Regulation of CD2-Mediated Activation

    Article • Cellular Immunology, September 1994, Elsevier

    Dr Jacques A NUNES

  47. Binding of phosphatidyl-inositol-3-OH kinase to CD28 is required for T-cell signalling

    Article • Nature, May 1994, Nature

    Dr Jacques A NUNES

  48. Functional expression of human CD28 in murine T cell hybridomas

    Article • Molecular Immunology, January 1994, Elsevier

    Dr Jacques A NUNES

  49. Anti-T11.1 and -T11.2 monoclonal antibodies play a different role in CD2-mediated signal transduction

    Article • Human Immunology, November 1993, Elsevier

    Dr Jacques A NUNES

  50. Regulation of CD2-Mediated Human T Cell Activation: Anti-CD8 Monoclonal Antibodies Inhibit CD2-Mediated Rise in Intracellular Calcium

    Article • Cellular Immunology, November 1993, Elsevier

    Dr Jacques A NUNES

  51. Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity

    Article • Biochemical Journal, August 1993, Portland Press Ltd.

    Dr Jacques A NUNES

  52. CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events

    Article • International Immunology, January 1993, Oxford University Press (OUP)

    Dr Jacques A NUNES

  53. Dissociation between early and late events in T cell activation mediated through CD28 surface molecule

    Article • Molecular Immunology, April 1991, Elsevier

    Dr Jacques A NUNES

  54. Monoclonal antibodies against LFA-1 or its ligand ICAM-1 accelerate CD2 (T11.1 + T11.2)-mediated T cell proliferation

    Article • Cellular Immunology, October 1989, Elsevier

    Dr Jacques A NUNES

  55. T cell activation via the CD2 molecule is associated with protein kinase C translocation from the cytosol to the plasma membrane

    Article • European Journal of Immunology, May 1989, Wiley

    Dr Jacques A NUNES

  56. Cholera toxin inhibits the increase in cytoplasmic free calcium induced via the CD2 pathway of human T-lymphocyte activation

    Article • Journal of Cellular Biochemistry, April 1989, Wiley

    Dr Jacques A NUNES

  57. Triggering CD 28 molecules synergize with CD 2 (T11.1 and T11,2)-mediated T cell activation

    Article • European Journal of Immunology, May 1988, Wiley

    Dr Jacques A NUNES

  58. Travel Informations on the TEC Kinases during Lymphocyte Activation

    Article • Springer Science + Business Media

    Dr Jacques A NUNES