All Stories

  1. Macular Pigment and Retinal Reflectance in a Feasibility Study of Multiple Sclerosis: Toward Novel Biomarkers of Hidden Disease Processes
  2. A practical starting guide to tear fluid biobanking
  3. Central and Peripheral Alterations of Retinal and Choroidal Vasculature in Multiple Sclerosis: Insights from Multimodal Imaging
  4. Quantification of retinal microvascular imaging features from fundus photos in ocular and systemic disease: a framework for standardization
  5. REACT-PXE: a consensus on diagnosis and future research concerning pseudoxanthoma elasticum (PXE)
  6. Levodopa in retinal disease: Dopamine pathways, neuroprotective mechanisms, and clinical evidence
  7. Investigating the Association between Cognitive Function with Retinal Thickness, Choroidal Thickness and Lens Opacities in People with and without Down Syndrome
  8. Retinal biomarkers for Alzheimer's disease in the prodromal and preclinical population ‐ The Deep and Frequent Phenotyping study
  9. Zinc in eye health, retinal biology and disease
  10. Development of Bioceramic Bone-Inspired Scaffolds Through Single-Step Melt-Extrusion 3D Printing for Segmental Defect Treatment
  11. 2024 Annual Meeting of the International Network on Ectopic Calcification (INTEC)—Abstract Proceedings
  12. Investigating the eye in Down syndrome as a window to Alzheimer’s disease: the REVEAL protocol – a clinical cross-sectional study
  13. International reporting guidelines for tear fluid research: A Delphi consensus
  14. A comprehensive scoping review of methodological approaches and clinical applications of tear fluid biomarkers
  15. Choroidal and retinal vascular changes in adults with Down syndrome: Insights into the Alzheimer's disease continuum
  16. Resistance and resilience to Alzheimer's disease in Down syndrome
  17. Ultra‐widefield retinal imaging in Down syndrome: A high‐risk population for Alzheimer's disease
  18. Dementia risk reduction in the African context: Multi‐national implementation of multimodal strategies to promote healthy brain aging in Africa (the Africa‐FINGERS project)
  19. Development of dual drug loaded-hydrogel scaffold combining microfluidics and coaxial 3D-printing for intravitreal implantation
  20. Application of Artificial Intelligence in Ophthalmology: An Updated Comprehensive Review
  21. Metabolomic changes in tear fluid following zinc biofortification in the BiZiFED nutritional study: a feasibility study
  22. Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation
  23. Bruch's Membrane Calcification in Pseudoxanthoma Elasticum
  24. Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions
  25. Reduced Cone Density Is Associated with Multiple Sclerosis
  26. Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia
  27. Two-Photon Excited Fluorescence Lifetime Imaging of Tetracycline-Labeled Retinal Calcification
  28. Editorial: Zinc in health and disease management
  29. Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium
  30. Fluorescence Lifetime Imaging of Human Sub-RPE Calcification In Vitro Following Chlortetracycline Infusion
  31. Optimised plasma sample preparation and LC‐MS analysis to support large‐scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial
  32. Zinc Supplementation Induced Transcriptional Changes in Primary Human Retinal Pigment Epithelium: A Single-Cell RNA Sequencing Study to Understand Age-Related Macular Degeneration
  33. Retinal Vascular Changes in Alzheimer's Dementia and Mild Cognitive Impairment: A Pilot Study Using Ultra-Widefield Imaging
  34. Ocular Biomarkers for Alzheimer Disease Dementia
  35. Zinc supplementation induced transcriptional changes in primary human retinal pigment epithelium: a single cell RNA sequencing study to understand age-related macular degeneration
  36. Nuclear and cellular, micro and nano calcification in Alzheimer's disease patients and correlation to phosphorylated Tau
  37. Re: Keenan et al.: Cluster Analysis and Genotype-Phenotype Assessment of Geographic Atrophy in Age-Related Macular Degeneration: AREDS2 Report 25 (Ophthalmology. 2021;5(11):1061-1073)
  38. A 2,7-dichlorofluorescein derivative to monitor microcalcifications
  39. A Potential New Role for Zinc in Age-Related Macular Degeneration through Regulation of Endothelial Fenestration
  40. Development of a Genotype Assay for Age-Related Macular Degeneration
  41. Characterization of Calcium Phosphate Spherical Particles in the Subretinal Pigment Epithelium–Basal Lamina Space in Aged Human Eyes
  42. Comment and response to the article “The clinical relevance of visualizing the peripheral retina”by Nicola Quinn, Lajos Csincsik, Erin Flynn, Christine A. Curcio, Szilard Kiss, SriniVas R. Sadda, Ruth Hogg, Tunde Peto & Imre Lengyel.
  43. Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning
  44. Increased choroidal thickness in adults with Down syndrome
  45. Multiplex bioimaging of proteins-related to neurodegenerative diseases in eye sections by laser ablation - Inductively coupled plasma – Mass spectrometry using metal nanoclusters as labels
  46. Retinal phenotyping of variants of Alzheimer's disease using ultra‐widefield retinal images
  47. Genotype- and Phenotype-Based Subgroups in Geographic Atrophy Secondary to Age-Related Macular Degeneration
  48. Integrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration
  49. A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium
  50. Fluorescent Arylphosphonic Acids: Synergic Interactions between Bone and the Fluorescent Core
  51. Nuclear and cellular, micro and nano calcification in Alzheimer’s disease patients and correlation to phosphorylated Tau
  52. Imaging hydroxyapatite in sub-retinal pigment epithelial deposits by fluorescence lifetime imaging microscopy with tetracycline staining
  53. Calcium, Diet, Imaging, and Age-Related Macular Degeneration
  54. Determination of Zn, Cu and Fe in human patients' serum using micro-sampling ICP-MS and sample dilution
  55. Correction to: Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia
  56. Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease
  57. P1‐273: ASSESSING HETEROGENEITY OF ALZHEIMER'S DISEASE THROUGH THE EYE
  58. Zinc Nutrition and Inflammation in the Aging Retina
  59. Metabolomics in serum of patients with non-advanced age-related macular degeneration reveals aberrations in the glutamine pathway
  60. THU0663 DO ANTIBODIES DIRECTED AGAINST HUMAN CILIARY BODY TISSUE PREDICT THE DEVELOPMENT OF UVEITIS IN JIA- A PRELIMINARY STUDY
  61. The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease
  62. On the origin of proteins in human drusen: The meet, greet and stick hypothesis
  63. Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer’s disease
  64. Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration
  65. Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration
  66. Fluorescence Lifetime Imaging of Tetracycline-Stained Retinal Hydroxyapatite: An Early Biomarker for Age-Related Macular Degeneration?
  67. Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia
  68. Metabolomics and Age-Related Macular Degeneration
  69. Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration
  70. A new perspective on lipid research in age-related macular degeneration
  71. The clinical relevance of visualising the peripheral retina
  72. Obesity, diabetes and zinc: A workshop promoting knowledge and collaboration between the UK and Israel, november 28–30, 2016 – Israel
  73. Precision medicine for age-related macular degeneration: current developments and prospects
  74. Genetic differences can cause changes in the level of several proteins in blood samples
  75. The effects of zinc supplementation on primary human retinal pigment epithelium
  76. Towards early detection of age-related macular degeneration with tetracyclines and FLIM
  77. Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration
  78. Peripheral Retinal Imaging Biomarkers for Alzheimer’s Disease: A Pilot Study
  79. Localization of the zinc binding tubulin polymerization promoting protein in the mice and human eye
  80. Prevalence of Age-Related Macular Degeneration in Europe
  81. Changes in zinc status and zinc transporters expression in whole blood of patients with Systemic Inflammatory Response Syndrome (SIRS)
  82. Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model
  83. Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study
  84. RETINAL IMAGING IN POSTERIOR CORTICAL ATROPHY AND TYPICAL ALZHEIMER’S DISEASE
  85. A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration–Like Lesions at the Peripheral Retina
  86. Retinal imaging in early-onset Alzheimer’s disease
  87. Retinal nerve fibre layer (RNFL) thinning in genetic ftd
  88. Correction for Thompson et al., Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
  89. Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
  90. Metals in age-related macular degeneration
  91. Zinc-induced self-association of complement C3b and Factor H: Implications for inflammation and age-related macular degeneration
  92. Zinc-induced Self-association of Complement C3b and Factor H: IMPLICATIONS FOR INFLAMMATION AND AGE-RELATED MACULAR DEGENERATION
  93. Zinc Binding to the Tyr402 and His402 Allotypes of Complement Factor H: Possible Implications for Age-Related Macular Degeneration
  94. The His402 allotype of complement factor H show similar self-association to the Tyr402 allotype but exhibits greater self-association in the presence of zinc
  95. Agreement between image grading of conventional (45°) and ultra wide-angle (200°) digital images in the macula in the Reykjavik eye study
  96. Bruch's membrane changes in transgenic mice overexpressing the human biglycan and apolipoprotein b-100 genes
  97. Uncontrolled Zinc- and Copper-Induced Oligomerisation of the Human Complement Regulator Factor H and Its Possible Implications for Function and Disease
  98. Uncontrolled zinc- and copper-induced oligomerisation of human complement factor H and its implications for age-related macular degeneration
  99. Reply to “Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)”
  100. Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)
  101. Cure or cause: opposing roles for zinc in age-related macular degeneration
  102. Bio‐avalibale zinc in the outer segments of short wavelength cones
  103. High concentration of zinc in sub-retinal pigment epithelial deposits
  104. Partial and full agonism in endomorphin derivatives: Comparison by null and operational model
  105. Autonomous activity of CaMKII is only transiently increased following the induction of long-term potentiation in the rat hippocampus
  106. Association of Drusen Deposition with Choroidal Intercapillary Pillars in the Aging Human Eye
  107. Enhancement of NMDA responses by β-amyloid peptides in the hippocampus in vivo
  108. Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc
  109. S100B-Mediated Inhibition of the Phosphorylation of GFAP Is Prevented by TRTK-12
  110. Molecular pathomechanisms of Alzheimer's disease
  111. Side Chain Modifications Change the Binding and Agonist Properties of Endomorphin 2
  112. Influence of Degradation on Binding Properties and Biological Activity of Endomorphin 1
  113. Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy
  114. Preparation of specifically tritiated endomorphins
  115. Auto‐inhibition of Ca2+/calmodulin‐dependent protein kinase II by its ATP‐binding domain
  116. Autonomous activity and autophosphorylation of CAMPK‐II in rat hippocampal slices: effects of tissue preparation
  117. Modulation of the Phosphorylation and Activity of Calcium/Calmodulin‐Dependent Protein Kinase II by Zinc
  118. Phosphorylation of a New Brain-specific Septin, G-septin, by cGMP-dependent Protein Kinase
  119. Simultaneous measurement of tyrosine hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells
  120. Phosphorylation of proteins in chick ciliary ganglion under conditions that induce long-lasting changes in synaptic transmission: phosphoprotein targets for nitric oxide action
  121. α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion
  122. Characterization of protein kinase and phosphatase systems in chick ciliary ganglion
  123. Calcium/Calmodulin‐Stimulated Protein Kinase II Is Present in Primary Cultures of Cerebral Endothelial Cells
  124. Pathological Phosphorylation Causes Neuronal Death: Effect of Okadaic Acid in Primary Culture of Cerebellar Granule Cells
  125. Zinc can modulate the phosphorylation and activity of CAMK in freshly isolated rat brain capillaries
  126. Chapter 26: Regulation of transendothelial transport in the cerebral microvessels: the role of second messengers-generating systems
  127. Early X-irradiation of rats—4. Decrease in phosphorylation of low molecular weight proteins in the olfactory bulb accompanies the loss of GABAergic microneurons
  128. Kinetics of Protein Phosphorylation in Microvessels Isolated from Rat Brain: Modulation by Second Messengers