All Stories

  1. Zinc in eye health, retinal biology and disease
  2. Development of Bioceramic Bone-Inspired Scaffolds Through Single-Step Melt-Extrusion 3D Printing for Segmental Defect Treatment
  3. 2024 Annual Meeting of the International Network on Ectopic Calcification (INTEC)—Abstract Proceedings
  4. Investigating the eye in Down syndrome as a window to Alzheimer’s disease: the REVEAL protocol – a clinical cross-sectional study
  5. International reporting guidelines for tear fluid research: A Delphi consensus
  6. A comprehensive scoping review of methodological approaches and clinical applications of tear fluid biomarkers
  7. Choroidal and retinal vascular changes in adults with Down syndrome: Insights into the Alzheimer's disease continuum
  8. Resistance and resilience to Alzheimer's disease in Down syndrome
  9. Ultra‐widefield retinal imaging in Down syndrome: A high‐risk population for Alzheimer's disease
  10. Dementia risk reduction in the African context: Multi‐national implementation of multimodal strategies to promote healthy brain aging in Africa (the Africa‐FINGERS project)
  11. Development of dual drug loaded-hydrogel scaffold combining microfluidics and coaxial 3D-printing for intravitreal implantation
  12. Application of Artificial Intelligence in Ophthalmology: An Updated Comprehensive Review
  13. Metabolomic changes in tear fluid following zinc biofortification in the BiZiFED nutritional study: a feasibility study
  14. Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation
  15. Bruch's Membrane Calcification in Pseudoxanthoma Elasticum
  16. Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions
  17. Reduced Cone Density Is Associated with Multiple Sclerosis
  18. Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia
  19. Two-Photon Excited Fluorescence Lifetime Imaging of Tetracycline-Labeled Retinal Calcification
  20. Editorial: Zinc in health and disease management
  21. Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium
  22. Fluorescence Lifetime Imaging of Human Sub-RPE Calcification In Vitro Following Chlortetracycline Infusion
  23. Optimised plasma sample preparation and LC‐MS analysis to support large‐scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial
  24. Zinc Supplementation Induced Transcriptional Changes in Primary Human Retinal Pigment Epithelium: A Single-Cell RNA Sequencing Study to Understand Age-Related Macular Degeneration
  25. Retinal Vascular Changes in Alzheimer's Dementia and Mild Cognitive Impairment: A Pilot Study Using Ultra-Widefield Imaging
  26. Ocular Biomarkers for Alzheimer Disease Dementia
  27. Zinc supplementation induced transcriptional changes in primary human retinal pigment epithelium: a single cell RNA sequencing study to understand age-related macular degeneration
  28. Nuclear and cellular, micro and nano calcification in Alzheimer's disease patients and correlation to phosphorylated Tau
  29. Re: Keenan et al.: Cluster Analysis and Genotype-Phenotype Assessment of Geographic Atrophy in Age-Related Macular Degeneration: AREDS2 Report 25 (Ophthalmology. 2021;5(11):1061-1073)
  30. A 2,7-dichlorofluorescein derivative to monitor microcalcifications
  31. A Potential New Role for Zinc in Age-Related Macular Degeneration through Regulation of Endothelial Fenestration
  32. Development of a Genotype Assay for Age-Related Macular Degeneration
  33. Characterization of Calcium Phosphate Spherical Particles in the Subretinal Pigment Epithelium–Basal Lamina Space in Aged Human Eyes
  34. Comment and response to the article “The clinical relevance of visualizing the peripheral retina”by Nicola Quinn, Lajos Csincsik, Erin Flynn, Christine A. Curcio, Szilard Kiss, SriniVas R. Sadda, Ruth Hogg, Tunde Peto & Imre Lengyel.
  35. Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning
  36. Increased choroidal thickness in adults with Down syndrome
  37. Multiplex bioimaging of proteins-related to neurodegenerative diseases in eye sections by laser ablation - Inductively coupled plasma – Mass spectrometry using metal nanoclusters as labels
  38. Retinal phenotyping of variants of Alzheimer's disease using ultra‐widefield retinal images
  39. Genotype- and Phenotype-Based Subgroups in Geographic Atrophy Secondary to Age-Related Macular Degeneration
  40. Integrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration
  41. A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium
  42. Fluorescent Arylphosphonic Acids: Synergic Interactions between Bone and the Fluorescent Core
  43. Nuclear and cellular, micro and nano calcification in Alzheimer’s disease patients and correlation to phosphorylated Tau
  44. Imaging hydroxyapatite in sub-retinal pigment epithelial deposits by fluorescence lifetime imaging microscopy with tetracycline staining
  45. Calcium, Diet, Imaging, and Age-Related Macular Degeneration
  46. Determination of Zn, Cu and Fe in human patients' serum using micro-sampling ICP-MS and sample dilution
  47. Correction to: Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia
  48. Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease
  49. P1‐273: ASSESSING HETEROGENEITY OF ALZHEIMER'S DISEASE THROUGH THE EYE
  50. Zinc Nutrition and Inflammation in the Aging Retina
  51. Metabolomics in serum of patients with non-advanced age-related macular degeneration reveals aberrations in the glutamine pathway
  52. THU0663 DO ANTIBODIES DIRECTED AGAINST HUMAN CILIARY BODY TISSUE PREDICT THE DEVELOPMENT OF UVEITIS IN JIA- A PRELIMINARY STUDY
  53. The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease
  54. On the origin of proteins in human drusen: The meet, greet and stick hypothesis
  55. Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer’s disease
  56. Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration
  57. Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration
  58. Fluorescence Lifetime Imaging of Tetracycline-Stained Retinal Hydroxyapatite: An Early Biomarker for Age-Related Macular Degeneration?
  59. Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia
  60. Metabolomics and Age-Related Macular Degeneration
  61. Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration
  62. A new perspective on lipid research in age-related macular degeneration
  63. The clinical relevance of visualising the peripheral retina
  64. Obesity, diabetes and zinc: A workshop promoting knowledge and collaboration between the UK and Israel, november 28–30, 2016 – Israel
  65. Precision medicine for age-related macular degeneration: current developments and prospects
  66. Genetic differences can cause changes in the level of several proteins in blood samples
  67. The effects of zinc supplementation on primary human retinal pigment epithelium
  68. Towards early detection of age-related macular degeneration with tetracyclines and FLIM
  69. Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration
  70. Peripheral Retinal Imaging Biomarkers for Alzheimer’s Disease: A Pilot Study
  71. Localization of the zinc binding tubulin polymerization promoting protein in the mice and human eye
  72. Prevalence of Age-Related Macular Degeneration in Europe
  73. Changes in zinc status and zinc transporters expression in whole blood of patients with Systemic Inflammatory Response Syndrome (SIRS)
  74. Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model
  75. Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study
  76. RETINAL IMAGING IN POSTERIOR CORTICAL ATROPHY AND TYPICAL ALZHEIMER’S DISEASE
  77. A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration–Like Lesions at the Peripheral Retina
  78. Retinal imaging in early-onset Alzheimer’s disease
  79. Retinal nerve fibre layer (RNFL) thinning in genetic ftd
  80. Correction for Thompson et al., Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
  81. Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
  82. Metals in age-related macular degeneration
  83. Zinc-induced self-association of complement C3b and Factor H: Implications for inflammation and age-related macular degeneration
  84. Zinc-induced Self-association of Complement C3b and Factor H: IMPLICATIONS FOR INFLAMMATION AND AGE-RELATED MACULAR DEGENERATION
  85. Zinc Binding to the Tyr402 and His402 Allotypes of Complement Factor H: Possible Implications for Age-Related Macular Degeneration
  86. The His402 allotype of complement factor H show similar self-association to the Tyr402 allotype but exhibits greater self-association in the presence of zinc
  87. Agreement between image grading of conventional (45°) and ultra wide-angle (200°) digital images in the macula in the Reykjavik eye study
  88. Bruch's membrane changes in transgenic mice overexpressing the human biglycan and apolipoprotein b-100 genes
  89. Uncontrolled Zinc- and Copper-Induced Oligomerisation of the Human Complement Regulator Factor H and Its Possible Implications for Function and Disease
  90. Uncontrolled zinc- and copper-induced oligomerisation of human complement factor H and its implications for age-related macular degeneration
  91. Reply to “Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)”
  92. Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)
  93. Cure or cause: opposing roles for zinc in age-related macular degeneration
  94. Bio‐avalibale zinc in the outer segments of short wavelength cones
  95. High concentration of zinc in sub-retinal pigment epithelial deposits
  96. Partial and full agonism in endomorphin derivatives: Comparison by null and operational model
  97. Autonomous activity of CaMKII is only transiently increased following the induction of long-term potentiation in the rat hippocampus
  98. Association of Drusen Deposition with Choroidal Intercapillary Pillars in the Aging Human Eye
  99. Enhancement of NMDA responses by β-amyloid peptides in the hippocampus in vivo
  100. Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc
  101. S100B-Mediated Inhibition of the Phosphorylation of GFAP Is Prevented by TRTK-12
  102. Molecular pathomechanisms of Alzheimer's disease
  103. Side Chain Modifications Change the Binding and Agonist Properties of Endomorphin 2
  104. Influence of Degradation on Binding Properties and Biological Activity of Endomorphin 1
  105. Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy
  106. Preparation of specifically tritiated endomorphins
  107. Auto‐inhibition of Ca2+/calmodulin‐dependent protein kinase II by its ATP‐binding domain
  108. Autonomous activity and autophosphorylation of CAMPK‐II in rat hippocampal slices: effects of tissue preparation
  109. Modulation of the Phosphorylation and Activity of Calcium/Calmodulin‐Dependent Protein Kinase II by Zinc
  110. Phosphorylation of a New Brain-specific Septin, G-septin, by cGMP-dependent Protein Kinase
  111. Simultaneous measurement of tyrosine hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells
  112. Phosphorylation of proteins in chick ciliary ganglion under conditions that induce long-lasting changes in synaptic transmission: phosphoprotein targets for nitric oxide action
  113. α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion
  114. Characterization of protein kinase and phosphatase systems in chick ciliary ganglion
  115. Calcium/Calmodulin‐Stimulated Protein Kinase II Is Present in Primary Cultures of Cerebral Endothelial Cells
  116. Pathological Phosphorylation Causes Neuronal Death: Effect of Okadaic Acid in Primary Culture of Cerebellar Granule Cells
  117. Zinc can modulate the phosphorylation and activity of CAMK in freshly isolated rat brain capillaries
  118. Chapter 26: Regulation of transendothelial transport in the cerebral microvessels: the role of second messengers-generating systems
  119. Early X-irradiation of rats—4. Decrease in phosphorylation of low molecular weight proteins in the olfactory bulb accompanies the loss of GABAergic microneurons
  120. Kinetics of Protein Phosphorylation in Microvessels Isolated from Rat Brain: Modulation by Second Messengers