All Stories

  1. Design, synthesis, pharmacological evaluation and in-silico analysis of quinazoline derivatives as potential therapeutic agents

    Article • Phosphorus Sulfur and Silicon and the Related Elements, March 2026, Taylor & Francis

    Professor Ibrahim F. Nassar

  2. Discovery of thiazolo[5′,4′:5,6]pyrido[2,3-d]pyrimidine, thiazolo[5′,4′:5,6]pyrido[2,3-d][1,3]oxazin & thiazolo[4,5-b]pyridine derivatives as novel CDK2 inhibitors: Synthesis, biological evaluation and in-silico studies

    Article • Journal of Molecular Structure, February 2026, Elsevier

    Professor Ibrahim F. Nassar

  3. Ring‐Chain Tautomerism (part II): Synthetic Applications of Biologically Active Five‐Membered Heterocycles With Two Heteroatoms

    Article • Journal of Heterocyclic Chemistry, September 2025, Wiley

    Professor Ibrahim F. Nassar

  4. Novel indoline analogues reverse resistant breast cancer via p-glycoprotein inhibition and apoptotic genes modulation

    Article • Journal of Molecular Structure, June 2025, Elsevier

    Dr Sameh S Zaghlool, Professor Ibrahim F. Nassar

  5. Green one-pot synthesis of a novel furan-2(3H)-one derivative: in vitro antiproliferative activity and DFT study

    Article • New Journal of Chemistry, January 2025, Royal Society of Chemistry

    Professor Sameh Ahmed Rizk, Professor Ibrahim F. Nassar

  6. New modified Benzimidazole derivatives carried on different sugars and nanocrystalline cellulose: Anticancer and antioxidant activity estimation.

    Article • Egyptian Journal of Chemistry, December 2024, Egypts Presidential Specialized Council for Education and Scientific Research

    Professor Ibrahim F. Nassar

  7. Structural simplification of Osimertinib to elaborate new indolyle-pyrimidine-5-carbonitrile derivatives with Anti-proliferative and Anti-SARS-CoV-2 activities assisted by molecular dynamic simulation

    Article • Tetrahedron, November 2024, Elsevier

    Professor Ibrahim F. Nassar

  8. A novel K-nearest neighbor classifier for lung cancer disease diagnosis

    Article • Neural Computing and Applications, September 2024, Springer Science + Business Media

    Professor Ibrahim F. Nassar

  9. Assessing the Efficacy of IoT-driven Machine Learning Models in Enhancing Chili Crop Growth and Yield Quality

    Article • August 2024, Springer Science + Business Media

    Professor Ibrahim F. Nassar

  10. Facile Synthesis, In silico Studies, and Biological Assessment of Novel Pyrazolo[3,4-b]pyridine Congeners

    Article • Egyptian Journal of Chemistry, May 2024, Egypts Presidential Specialized Council for Education and Scientific Research

    Professor Ibrahim F. Nassar

  11. Synthesis, molecular modeling Insights, and anticancer assessment of novel polyfunctionalized Pyridine congeners

    Article • Bioorganic Chemistry, December 2023, Elsevier

    Professor Ibrahim F. Nassar

  12. Development of pyrolo[2,3-c]pyrazole, pyrolo[2,3-d]pyrimidine and their bioisosteres as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological evaluation and molecular dynamics investigations

    Article • Bioorganic Chemistry, October 2023, Elsevier

    Professor Ibrahim F. Nassar

  13. New Indole Derivatives As Multitarget anti-Alzheimer's Agents: synthesis, Biological Evaluation and Molecular Dynamics

    Article • Future Medicinal Chemistry, March 2023, Taylor & Francis

    Professor Ibrahim F. Nassar

  14. Synthesis, Antitumor, Antimicrobial and Anti-Hepatities B Activities of New 3-(4-chlorophenyl)-N-(p-tolyl)acrylamide Chalcone Derivatives

    Article • Egyptian Journal of Chemistry, February 2023, Egypts Presidential Specialized Council for Education and Scientific Research

    Professor Ibrahim F. Nassar

  15. Development of Pyrolo[2,3-C]Pyrazole, Pyrolo[2,3-D]Pyrimidine and Their Bioisosteres as Novel CDK2 Inhibitors with Potent <i>in Vitro</i> Apoptotic Anti-Proliferative Activity: Synthesis, Biological Evaluation and Molecular Dynamics Invest...

    Article • January 2023, Elsevier

    Professor Ibrahim F. Nassar

  16. Mechanistic study of Hg(II) interaction with three different α-aminophosphonate adsorbents: Insights from batch experiments and theoretical calculations

    Article • Chemosphere, October 2022, Elsevier

    Professor Ibrahim F. Nassar

  17. Synthesis, biological evaluation, and in silico studies of new CDK2 inhibitors based on pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold with apoptotic activity

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, July 2022, Taylor & Francis

    Professor Ibrahim F. Nassar

  18. Design, Synthesis and Biological Evaluation of Novel Pyrano[2,3-c]pyrazoles And Their Sugar Derivatives as Antimicrobial, Antioxidant and Anticancer Agents

    Article • Egyptian Journal of Chemistry, June 2022, Egypts Presidential Specialized Council for Education and Scientific Research

    Professor Ibrahim F. Nassar

  19. SYNTHESIS AND ANTICANCER ACTIVITY TOWARDS HEPG-2 AND MCF-7 OF NEW 2-AMINO-1,3,4-THIADIAZOLE AND THEIR SUGAR DERIVATIVES

    Article • Universal Journal of Pharmaceutical Research, May 2022, Society of Pharmaceutical Tecnocrats

    Professor Ibrahim F. Nassar

  20. Discovery of pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as novel CDK2 inhibitors: synthesis, biological and molecular modeling investigations

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Professor Ibrahim F. Nassar

  21. Synthesis and Anticancer Activity of New Pyrimidine and Oxadiazole Acyclic Nucleoside Analogs and Thiazolopyrimidine Derivatives

    Article • Russian Journal of General Chemistry, October 2021, Pleiades Publishing Ltd

    Professor Ibrahim F. Nassar

  22. N-substituted 5-(oxoindolinyl)-2-thioxo- thiazolidinone

    Article • Letters in Drug Design & Discovery, August 2021, Bentham Science Publishers

    Professor Ibrahim F. Nassar

  23. Discovery of New Pyrazolopyridine, Furopyridine, and Pyridine Derivatives as CDK2 Inhibitors: Design, Synthesis, Docking Studies, and Anti-Proliferative Activity

    Article • Molecules, June 2021, MDPI AG

    Professor Ibrahim F. Nassar

  24. Synthesis, Docking and Anticancer Evaluation of New Pyridine-3-Carbonitrile Derivatives

    Article • Polycyclic Aromatic Compounds, January 2021, Taylor & Francis

    Professor Ibrahim F. Nassar

  25. A comparative study of metal-catalyzed three-component synthesis of α-aminophosphonates

    Article • Current Chemistry Letters, January 2021, Growing Science

    Professor Ibrahim F. Nassar

  26. Synthesis of New Furanone Derivatives with Potent Anticancer Activity

    Article • Russian Journal of Bioorganic Chemistry, November 2020, Pleiades Publishing Ltd

    Professor Ibrahim F. Nassar

  27. Synthesis of Some New Pyrazoline-Based Thiazole Derivatives and Evaluation of Their Antimicrobial, Antifungal, and Anticancer Activities

    Article • Russian Journal of Bioorganic Chemistry, May 2020, Pleiades Publishing Ltd

    Professor Ibrahim F. Nassar

  28. Synthesis of new uracil derivatives and their sugar hydrazones with potent antimicrobial, antioxidant and anticancer activities

    Article • Nucleosides Nucleotides & Nucleic Acids, March 2020, Taylor & Francis

    Professor Ibrahim F. Nassar

  29. Synthesis, Docking Studies into CDK-2 and Anticancer Activity of New Derivatives Based Pyrimidine Scaffold and Their Derived Glycosides

    Article • Mini-Reviews in Medicinal Chemistry, August 2019, Bentham Science Publishers

    Professor Ibrahim F. Nassar

  30. Synthesis and Anticancer Activity of New Substituted Piperidinones Linked to Pyrimidine, Thiazole, and Triazole Glycoside Derivatives

    Article • Russian Journal of General Chemistry, August 2019, Pleiades Publishing Ltd

    Professor Ibrahim F. Nassar

  31. Synthesis and Anticancer Activity of New ((Furan-2-yl)-1,3,4-thiadiazolyl)-1,3,4-oxadiazole Acyclic Sugar Derivatives

    Article • Chemical and Pharmaceutical Bulletin, August 2019, Pharmaceutical Society of Japan

    Professor Ibrahim F. Nassar

  32. Design, Synthesis, and Anticancer Activity of New Oxadiazolyl‐Linked and Thiazolyl‐Linked Benzimidazole Arylidines, Thioglycoside, and Acyclic Analogs

    Article • Journal of Heterocyclic Chemistry, January 2019, Wiley

    Professor Ibrahim F. Nassar

  33. Design, Synthesis of Novel Pyridine and Pyrimidine Sugar Compounds as Antagonists Targeting the ERα via Structure-Based Virtual Screening

    Article • Mini-Reviews in Medicinal Chemistry, August 2018, Bentham Science Publishers

    Professor Ibrahim F. Nassar, tamer ragab

  34. Utility of thiophene-2-carbonyl isothiocyanate as a precursor for the synthesis of 1,2,4-triazole, 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives with evaluation of their antitumor and antimicrobial activities

    Article • Phosphorus Sulfur and Silicon and the Related Elements, July 2018, Taylor & Francis

    Professor Ibrahim F. Nassar

  35. Synthesis and Anticancer Activity of Some New Fused Pyrazoles and Their Glycoside Derivatives

    Article • Journal of Heterocyclic Chemistry, June 2018, Wiley

    Professor Fathy Mohamed Abdelrazek, Professor Ibrahim F. Nassar

  36. Design, synthesis and anticancer evaluation of novel pyrazole, pyrazolo[3,4-d]pyrimidine and their glycoside derivatives

    Article • Nucleosides Nucleotides & Nucleic Acids, March 2017, Taylor & Francis

    Professor Ibrahim F. Nassar

  37. Magnetic NiFe2O4nanoparticles: efficient, heterogeneous and reusable catalyst for synthesis of acetylferrocene chalcones and their anti-tumour activity

    Article • Applied Organometallic Chemistry, June 2016, Wiley

    Prof. Dr. ِِAhmed Mohammed Abu-Dief, Professor Ibrahim F. Nassar

  38. A convenient synthesis and molecular modeling study of novel pyrazolo[3,4-d]pyrimidine and pyrazole derivatives as anti-tumor agents

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, July 2014, Taylor & Francis

    Professor Ibrahim F. Nassar

  39. Ethyl 5-amino-1-[(4-methylphenyl)sulfonyl]-1H-pyrazole-4-carboxylate

    Article • Acta Crystallographica Section E Structure Reports Online, August 2013, International Union of Crystallography

    Professor Ibrahim F. Nassar

  40. Synthesis and Antitumor Activity of New Substituted Mercapto-1,2,4-Triazine Derivatives, Their Thioglycosides, and Acyclic Thioglycoside Analogs

    Article • Journal of Heterocyclic Chemistry, January 2013, Wiley

    Professor Ibrahim F. Nassar

  41. N-aryl pyrazoles: DFT calculations of CH acidity and deprotonative metallation using a combination of lithium and zinc amides

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Professor Ibrahim F. Nassar

  42. Synthesis and antitumor activity of new 1,2,4-triazine and [1,2,4]triazolo[4,3-b][1,2,4]triazine derivatives and their thioglycoside and acyclic C-nucleoside analogs

    Article • Journal of Heterocyclic Chemistry, September 2010, Wiley

    Professor Ibrahim F. Nassar

  43. Synthesis of some quinazolines derived from 6,8-dibromo2-(2-carboxyphenyl)-4h-3,1-benzoxazin-4-one as antimicrobial agents

    Article • Chemistry of Heterocyclic Compounds, December 2009, Springer Science + Business Media

    Professor Ibrahim F. Nassar

  44. C-Furyl glycosides, II: synthesis and antimicrobial evaluation of C-furyl glycosides bearing pyrazolines, isoxazolines, and 5,6-dihydropyrimidine-2(1H)-thiones

    Article • Monatshefte für Chemie - Chemical Monthly, September 2008, Springer Science + Business Media

    Professor Ibrahim F. Nassar

  45. Corrosion inhibition of Tubing steel during acidization of oil and gas wells

    Article • Electrochimica Acta, February 2008, Elsevier

    Professor Ibrahim F. Nassar

  46. Unsaturated polyester resins based on rosin maleic anhydride adduct as corrosion protections of steel

    Article • Reactive and Functional Polymers, July 2007, Elsevier

    Professor Ibrahim F. Nassar

  47. Synthesis of Heterobicyclic Nitrogen Compounds as Molluscicide Agents Derived from 6-Methyl-5-styryl-1,2,4-triazin-3-thiol: Part I

    Article • Phosphorus Sulfur and Silicon and the Related Elements, February 2003, Taylor & Francis

    Professor Ibrahim F. Nassar