All Stories

  1. Improving the viability of tissue‐resident stem cells using an organ‐preservation solution

    Article • FEBS Open Bio, November 2019, Wiley

    Dr Hiroshi Kubo

  2. Hospitalization costs and length of stay of Japanese children with respiratory syncytial virus

    Article • Medicine, July 2018, Wolters Kluwer Health

    Dr Hiroshi Kubo

  3. Guselkumab, an anti-interleukin-23 monoclonal antibody, for the treatment of moderate to severe plaque-type psoriasis in Japanese patients: Efficacy and safety results from a phase 3, randomized, double-blind, placebo-controlled study

    Article • The Journal of Dermatology, June 2018, Wiley

    Dr Hiroshi Kubo

  4. Guselkumab, a human interleukin-23 monoclonal antibody in Japanese patients with generalized pustular psoriasis and erythrodermic psoriasis: Efficacy and safety analyses of a 52-week, phase 3, multicenter, open-label study

    Article • The Journal of Dermatology, March 2018, Wiley

    Dr Hiroshi Kubo

  5. Efficacy and Safety of Guselkumab, an Anti–interleukin 23 Monoclonal Antibody, for Palmoplantar Pustulosis

    Article • JAMA Dermatology, March 2018, American Medical Association (AMA)

    Dr Hiroshi Kubo

  6. Safety and efficacy of guselkumab in Japanese patients with moderate-to-severe plaque psoriasis: a randomized, placebo-controlled, ascending-dose study

    Article • British Journal of Dermatology, January 2018, Wiley

    Dr Hiroshi Kubo

  7. Extracellular Vesicles in Lung Disease

    Article • CHEST Journal, January 2018, Elsevier

    Dr Hiroshi Kubo

  8. Impact of patient characteristics and treatment procedures on hospitalization cost and length of stay in Japanese patients with influenza: A structural equation modelling approach

    Article • Influenza and Other Respiratory Viruses, October 2017, Wiley

    Dr Jörg Mahlich, Dr Hiroshi Kubo

  9. Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype

    Article • Laboratory Investigation, May 2017, Nature

    Dr Hiroshi Kubo

  10. Serum extracellular vesicular miR-21-5p is a predictor of the prognosis in idiopathic pulmonary fibrosis

    Article • September 2016, Springer Science + Business Media

    Dr Hiroshi Kubo

  11. Increased rhinovirus replication in nasal mucosa cells in allergic subjects is associated with increased ICAM‐1 levels and endosomal acidification and is inhibited by L‐carbocisteine

    Article • Immunity Inflammation and Disease, April 2016, Wiley

    Dr Hiroshi Kubo

  12. Novel Monoclonal Antibody LpMab-17 Developed by CasMab Technology Distinguishes Human Podoplanin from Monkey Podoplanin

    Article • Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, April 2016, Mary Ann Liebert Inc

    Dr Hiroshi Kubo

  13. Isolation of individual cellular components from lung tissues of patients with lymphangioleiomyomatosis

    Article • AJP Lung Cellular and Molecular Physiology, March 2016, American Physiological Society

    Dr Hiroshi Kubo

  14. Receptor for advanced glycation end products expressed on alveolar epithelial cells is the main target for hyperoxia-induced lung injury

    Article • Respiratory Investigation, March 2016, Elsevier

    Dr Hiroshi Kubo

  15. The non-antibiotic macrolide EM900 inhibits rhinovirus infection and cytokine production in human airway epithelial cells

    Article • Physiological Reports, October 2015, Wiley

    Dr Hiroshi Kubo

  16. The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model

    Article • Transplantation Direct, October 2015, Wolters Kluwer Health

    Dr Hiroshi Kubo

  17. Increased circulating alveolar epithelial microparticles in COPD patients

    Article • September 2015, European Respiratory Society (ERS)

    Dr Hiroshi Kubo

  18. Establishment of alveolar epithelial progenitor cells from the lung with ABCA3 mutations

    Article • September 2015, European Respiratory Society (ERS)

    Dr Hiroshi Kubo

  19. The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells

    Article • Pulmonary Pharmacology & Therapeutics, August 2015, Elsevier

    Dr Hiroshi Kubo

  20. Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosisin vivo

    Article • Experimental Lung Research, July 2015, Taylor & Francis

    Dr Hiroshi Kubo

  21. Pulmonary administration of Am80 regenerates collapsed alveoli

    Article • Journal of Controlled Release, December 2014, Elsevier

    Dr Hiroshi Kubo

  22. Poster Presentation – Others

    Article • Respirology, October 2014, Wiley

    Dr Hiroshi Kubo

  23. Cyclin-dependent kinase-specific activity predicts the prognosis of stage I and stage II non-small cell lung cancer

    Article • BMC Cancer, October 2014, Springer Science + Business Media

    Dr Hiroshi Kubo

  24. Magnitude of influenza virus replication and cell damage is associated with interleukin-6 production in primary cultures of human tracheal epithelium

    Article • Respiratory Physiology & Neurobiology, October 2014, Elsevier

    Dr Hiroshi Kubo

  25. Additional treatment with clarithromycin reduces fever duration in patients with influenza

    Article • Respiratory Investigation, September 2014, Elsevier

    Dr Hiroshi Kubo

  26. Pulmonary administration of integrin-nanoparticles regenerates collapsed alveoli

    Article • Journal of Controlled Release, August 2014, Elsevier

    Dr Hiroshi Kubo

  27. Formoterol and budesonide inhibit rhinovirus infection and cytokine production in primary cultures of human tracheal epithelial cells

    Article • Respiratory Investigation, July 2014, Elsevier

    Dr Hiroshi Kubo

  28. The effects of neuraminidase inhibitors on the release of oseltamivir-sensitive and oseltamivir-resistant influenza viruses from primary cultures of human tracheal epithelium

    Article • Journal of Medical Virology, May 2014, Wiley

    Dr Hiroshi Kubo

  29. The role of microparticles in chronic obstructive pulmonary disease

    Article • International Journal of Chronic Obstructive Pulmonary Disease, March 2014, Taylor & Francis

    Dr Hiroshi Kubo, Dr Toru Takahashi

  30. Annual FEV1 changes and numbers of circulating endothelial microparticles in patients with COPD: a prospective study

    Article • BMJ Open, March 2014, BMJ

    Dr Hiroshi Kubo, Dr Toru Takahashi

  31. c-Kit immunoexpression delineates a putative endothelial progenitor cell population in developing human lungs

    Article • AJP Lung Cellular and Molecular Physiology, February 2014, American Physiological Society

    Dr Hiroshi Kubo

  32. Addition of oral cavity brushing and rehabilitation reduces fever in tube‐fed patients

    Article • Geriatrics and Gerontology International, October 2013, Wiley

    Dr Hiroshi Kubo

  33. The increase of microRNA-21 during lung fibrosis and its contribution to epithelial-mesenchymal transition in pulmonary epithelial cells

    Article • Respiratory Research, September 2013, Springer Science + Business Media

    Dr Hiroshi Kubo

  34. Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells

    Article • Physiological Reports, August 2013, Wiley

    Dr Hiroshi Kubo

  35. Ambroxol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells

    Article • Archives of Pharmacal Research, July 2013, Springer Science + Business Media

    Dr Hiroshi Kubo

  36. A Placebo-controlled Randomized Trial of Warfarin in Idiopathic Pulmonary Fibrosis: A Hidden Subgroup?

    Article • American Review of Respiratory Disease, May 2013, American Thoracic Society

    Dr Hiroshi Kubo

  37. Released Endothelial Microparticles In Vitro

    Article • Experimental Lung Research, April 2013, Taylor & Francis

    Dr Hiroshi Kubo, Dr Toru Takahashi

  38. Total synthesis and biological evaluation of (−)-exiguolide analogues: importance of the macrocyclic backbone

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Dr Hiroshi Kubo, Prof. Dr. Haruhiko Fuwa

  39. Increased Severity of 2009 Pandemic Influenza A Virus Subtype H1N1 Infection in Alveolar Type II Cells From Patients With Pulmonary Fibrosis

    Article • The Journal of Infectious Diseases, November 2012, Oxford University Press (OUP)

    Dr Hiroshi Kubo

  40. Levofloxacin Inhibits Rhinovirus Infection in Primary Cultures of Human Tracheal Epithelial Cells

    Article • Antimicrobial Agents and Chemotherapy, September 2012, ASM Journals

    Dr Hiroshi Kubo

  41. Analysis of gene expression profiles in alveolar epithelial type II-like cells differentiated from human alveolar epithelial progenitor cells

    Article • Respiratory Investigation, September 2012, Elsevier

    Dr Hiroshi Kubo

  42. Increased circulating endothelial microparticles in COPD patients: a potential biomarker for COPD exacerbation susceptibility

    Article • Thorax, July 2012, BMJ

    Dr Hiroshi Kubo, Dr Toru Takahashi

  43. Concise Review: Clinical Prospects for Treating Chronic Obstructive Pulmonary Disease with Regenerative Approaches

    Article • Stem Cells Translational Medicine, July 2012, Oxford University Press (OUP)

    Dr Hiroshi Kubo

  44. Levofloxacin Inhibits Rhinovirus Infection in Primary Cultures of Human Tracheal Epithelial Cells

    Article • Antimicrobial Agents and Chemotherapy, May 2012, ASM Journals

    Dr Hiroshi Kubo

  45. L-Carbocisteine Inhibits Respiratory Syncytial Virus Infection In Human Airway Epithelial Cells

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  46. Formoterol And Budesonide Inhibit Rhinovirus Infection In Human Airway Epithelial Cells

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  47. Tulobuterol Inhibits Rhinovirus Infection In Human Airway Epithelial Cells

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  48. Number Of Circulating Endothelial Microparticles Are Increased During Acute Exacerbation Of COPD; Potential Biomarkers For Progression Of Exacerbation

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  49. Gene Expression Profiles Of Alveolar Type II Cells From COPD Patients

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  50. Supplementation Of MiR-200c Or Inhibition Of MiR-21 Attenuates TGF-ß-Induced Epithelial-Mesenchymal Transition In Mouse Alveolar Type II Cells

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  51. An Anti-Cancer Effect Of Newly Synthesized Marine Macrolide, (-)-Exiguolide

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  52. Histone Deacetylase Inhibitor Restores The Gene Expression Of Human Lung Surfactant Protein C During Epithelial-Mesenchymal Transition In Vitro

    Article • May 2012, American Thoracic Society

    Dr Hiroshi Kubo

  53. A Novel Method for Isolating Individual Cellular Components from the Adult Human Distal Lung

    Article • American Journal of Respiratory Cell and Molecular Biology, April 2012, American Thoracic Society

    Dr Hiroshi Kubo

  54. Repetitive pneumonia and wheezing in an elderly patient after radiation therapy

    Article • Geriatrics and Gerontology International, March 2012, Wiley

    Dr Hiroshi Kubo

  55. Tissue engineering for pulmonary diseases: Insights from the laboratory

    Article • Respirology, March 2012, Wiley

    Dr Hiroshi Kubo

  56. Inhibitory effects of tiotropium on rhinovirus infection in human airway epithelial cells

    Article • European Respiratory Journal, February 2012, European Respiratory Society (ERS)

    Dr Hiroshi Kubo

  57. Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma

    Article • Cancer Science, February 2012, Wiley

    Dr Hiroshi Kubo

  58. l-carbocisteine inhibits respiratory syncytial virus infection in human tracheal epithelial cells

    Article • Respiratory Physiology & Neurobiology, January 2012, Elsevier

    Dr Hiroshi Kubo

  59. Gene expression profiles of alveolar type II cells of chronic obstructive pulmonary disease: a case–control study

    Article • BMJ Open, January 2012, BMJ

    Dr Hiroshi Kubo

  60. Administration of a specific inhibitor of neutrophil elastase attenuates pulmonary fibrosis after acute lung injury in mice

    Article • Experimental Lung Research, December 2011, Taylor & Francis

    Dr Hiroshi Kubo

  61. Prevention of Chronic Obstructive Pulmonary Disease Exacerbation by Angiotensin-Converting Enzyme Inhibitors in Individuals with Impaired Swallowing

    Article • Journal of the American Geriatrics Society, October 2011, Wiley

    Dr Hiroshi Kubo

  62. Evidence for Human Lung Stem Cells

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, August 2011, New England Journal of Medicine (NEJM/MMS)

    Dr Hiroshi Kubo

  63. Surfactant protein C G100S mutation causes familial pulmonary fibrosis in Japanese kindred

    Article • European Respiratory Journal, August 2011, European Respiratory Society (ERS)

    Dr Hiroshi Kubo

  64. A New Flow-Cytometric Method For Isolating Component Cells Individually From Adult Human Distal Lungs

    Article • May 2011, American Thoracic Society

    Dr Hiroshi Kubo

  65. A Novel Differentiation Assay System For Human Alveolar Epithelial Type II Cells From Alveolar Epithelial Stem/Progenitor Cells In Vitro

    Article • May 2011, American Thoracic Society

    Dr Hiroshi Kubo

  66. Expression Patterns Of Two Important Regulatory Micrornas In Epithelial-Mesenchymal Transition During Experimental Bleomycin-Induced Lung Fibrosis

    Article • May 2011, American Thoracic Society

    Dr Hiroshi Kubo

  67. Circulating Endothelial Microparticles Are Increased In Patients With COPD; A Potential Novel Biomarker For COPD

    Article • May 2011, American Thoracic Society

    Dr Hiroshi Kubo

  68. An Anti-Cancer Effect Of Newly Synthesized Macrolide Compounds

    Article • May 2011, American Thoracic Society

    Dr Hiroshi Kubo

  69. Impaired endothelial progenitor cell mobilization and colony-forming capacity in chronic obstructive pulmonary disease

    Article • Respirology, April 2011, Wiley

    Dr Hiroshi Kubo

  70. The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury

    Article • Cellular and Molecular Immunology, April 2011, Springer Science + Business Media

    Dr Hiroshi Kubo, Prof Mochammad Hatta

  71. Molecular basis of lung tissue regeneration

    Article • General Thoracic and Cardiovascular Surgery, April 2011, Springer Science + Business Media

    Dr Hiroshi Kubo

  72. Receptor for advanced glycation end products binds to phosphatidylserine and assists in the clearance of apoptotic cells

    Article • EMBO Reports, March 2011, EMBO

    Dr Hiroshi Kubo, Dr Toru Takahashi

  73. Isolation of alveolar epithelial type II progenitor cells from adult human lungs

    Article • Laboratory Investigation, March 2011, Elsevier

    Dr Hiroshi Kubo

  74. Inducible disruption of autophagy in the lung causes airway hyper-responsiveness

    Article • Biochemical and Biophysical Research Communications, February 2011, Elsevier

    Dr Hiroshi Kubo

  75. Total Synthesis and Biological Assessment of (−)‐Exiguolide and Analogues

    Article • Chemistry - A European Journal, January 2011, Wiley

    Dr Hiroshi Kubo, Prof. Dr. Haruhiko Fuwa

  76. Procaterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells

    Article • European Journal of Pharmacology, January 2011, Elsevier

    Dr Hiroshi Kubo

  77. Inhibitory effects of carbocisteine on type A seasonal influenza virus infection in human airway epithelial cells

    Article • AJP Lung Cellular and Molecular Physiology, June 2010, American Physiological Society

    Dr Hiroshi Kubo

  78. Autotaxin Is Involved In Pulmonary Edema During Acid-induced Acute Lung Injury

    Article • May 2010, American Thoracic Society

    Dr Hiroshi Kubo

  79. Isolation Of Alveolar Epithelial Type II Progenitor Cells From The Adult Human Lungs

    Article • May 2010, American Thoracic Society

    Dr Hiroshi Kubo

  80. Tiotropium Inhibits Rhinovirus Infection In Human Airway Epithelial Cells

    Article • May 2010, American Thoracic Society

    Dr Hiroshi Kubo

  81. Levofloxacin Inhibits Rhinovirus Infection In Human Airway Epithelial Cells

    Article • May 2010, American Thoracic Society

    Dr Hiroshi Kubo

  82. Dynamic And Multilineage Expression Of C-kit In Developing Human Lungs

    Article • May 2010, American Thoracic Society

    Dr Hiroshi Kubo

  83. Tranexamic Acid Inhibits Infection Of Seasonal Human Influenza Virus In Airway Epithelial Cells

    Article • May 2010, American Thoracic Society

    Dr Hiroshi Kubo

  84. Mobilization Of Endothelial Progenitor Cells By Thoracic Surgery Was Decreased In Patients With Pulmonary Emphysema

    Article • May 2010, American Thoracic Society

    Dr Hiroshi Kubo

  85. Isolation and Characterization of Murine Multipotent Lung Stem Cells

    Article • Stem Cells and Development, April 2010, Mary Ann Liebert Inc

    Dr Hiroshi Kubo

  86. Lung Repair and Regeneration — Animal Models

    Article • March 2010, World Scientific Pub Co Pte Lt

    Dr Hiroshi Kubo

  87. Clarithromycin Inhibits Type A Seasonal Influenza Virus Infection in Human Airway Epithelial Cells

    Article • Journal of Pharmacology and Experimental Therapeutics, December 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Hiroshi Kubo

  88. Carbocisteine inhibits oxidant-induced apoptosis in cultured human airway epithelial cells

    Article • Respirology, September 2009, Wiley

    Dr Hiroshi Kubo

  89. Seizure and Pneumonia in an Elderly Patient with Systemic Lupus Erythematosus

    Article • Journal of the American Geriatrics Society, September 2009, Wiley

    Dr Hiroshi Kubo

  90. Macrolide antibiotics inhibit respiratory syncytial virus infection in human airway epithelial cells

    Article • Antiviral Research, August 2009, Elsevier

    Dr Hiroshi Kubo

  91. l-Carbocisteine reduces neutrophil elastase-induced mucin production

    Article • Respiratory Physiology & Neurobiology, June 2009, Elsevier

    Dr Hiroshi Kubo

  92. Effects of pneumococcal vaccination on hospitalization and exacerbations in elderly Japanese chronic obstructive pulmonary disease patients

    Article • Geriatrics and Gerontology International, May 2009, Wiley

    Dr Hiroshi Kubo

  93. New Preservation Solution for Endogenous Tissue Stem Cells.

    Article • April 2009, American Thoracic Society

    Dr Hiroshi Kubo

  94. Ambroxol Inhibits Rhinovirus Infection in Human Airway Epithelial Cells.

    Article • April 2009, American Thoracic Society

    Dr Hiroshi Kubo

  95. Inhibitory Effects of Procaterol on Rhinovirus Infection in Human Airway Epithelium.

    Article • April 2009, American Thoracic Society

    Dr Hiroshi Kubo

  96. Mesenchymal Stem Cells with Alveolar Epithelial Phenotype Were Isolated from Adult Human Lungs.

    Article • April 2009, American Thoracic Society

    Dr Hiroshi Kubo

  97. Carbocisteine Inhibits Receptor Expression and Infection of Human Influenza Virus in Airway Epithelial Cells.

    Article • April 2009, American Thoracic Society

    Dr Hiroshi Kubo

  98. CD117 Positive Cells without Mast Cell Lineage Are Localized in the Lung Parenchyma and Alveolar Wall in Adult Human Lungs.

    Article • April 2009, American Thoracic Society

    Dr Hiroshi Kubo

  99. A Macrolide Antibiotic Clarithromycin Inhibits Receptor Expression and Infection of Human Influenza Virus in Airway Epithelial Cells.

    Article • April 2009, American Thoracic Society

    Dr Hiroshi Kubo

  100. Intranasal HGF Administration Ameliorates the Physiologic and Morphologic Changes in Lung Emphysema

    Article • Molecular Therapy, August 2008, Elsevier

    Dr Hiroshi Kubo

  101. Identification of Pendrin as a Common Mediator for Mucus Production in Bronchial Asthma and Chronic Obstructive Pulmonary Disease

    Article • The Journal of Immunology, April 2008, The American Association of Immunologists

    Dr Hiroshi Kubo

  102. Submucosal gland cells in human lower airways produce MUC5AC protein

    Article • Respirology, March 2008, Wiley

    Dr Hiroshi Kubo

  103. Erythromycin attenuates MUC5AC synthesis and secretion in cultured human tracheal cells infected with RV14

    Article • Respirology, February 2008, Wiley

    Dr Hiroshi Kubo

  104. Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice

    Article • Journal of Clinical Investigation, October 2007, American Society for Clinical Investigation

    Dr Hiroshi Kubo, Akira Suzuki

  105. The role of the receptor for advanced glycation end-products in lung fibrosis

    Article • AJP Lung Cellular and Molecular Physiology, September 2007, American Physiological Society

    Dr Hiroshi Kubo

  106. RESPONSE LETTER TO DR. ANTON

    Article • Journal of the American Geriatrics Society, June 2007, Wiley

    Dr Hiroshi Kubo

  107. Impairment of the swallowing reflex in exacerbations of COPD

    Article • Thorax, May 2007, BMJ

    Dr Hiroshi Kubo

  108. Endogenous Secretory Receptor for Advanced Glycation End Products in Non–Small Cell Lung Carcinoma

    Article • American Review of Respiratory Disease, January 2007, American Thoracic Society

    Dr Hiroshi Kubo

  109. Possibility of alveolar regeneration

    Article • Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics, January 2007, The Japan Geriatrics Society

    Dr Hiroshi Kubo

  110. Mechanisms of mucin production by rhinovirus infection in cultured human airway epithelial cells

    Article • Respiratory Physiology & Neurobiology, December 2006, Elsevier

    Dr Hiroshi Kubo

  111. Interleukin-1β gene polymorphisms associated with risk of lung cancer in Japanese

    Article • Lung Cancer, November 2006, Elsevier

    Dr Hiroshi Kubo

  112. Interaction of non-adherent suspended neutrophils to complement opsonized pathogens: a new assay using optical traps

    Article • BDJ, October 2006, Springer Science + Business Media

    Dr Hiroshi Kubo

  113. PARALYTIC ILEUS AFTER DISCONTINUATION OF CHOLINESTERASE INHIBITOR

    Article • Journal of the American Geriatrics Society, October 2006, Wiley

    Dr Hiroshi Kubo

  114. IL-17A promotes the growth of airway epithelial cells through ERK-dependent signaling pathway

    Article • Biochemical and Biophysical Research Communications, September 2006, Elsevier

    Dr Hiroshi Kubo

  115. DYSPHAGIA IN A PATIENT WITH RAPIDLY ENLARGED THORACIC AORTIC ANEURYSM

    Article • Journal of the American Geriatrics Society, August 2006, Wiley

    Dr Hiroshi Kubo

  116. ARTERIAL CARBOXYHEMOGLOBIN CONCENTRATIONS AS A PREDICTOR OF CHEMOSENSITIVITY IN ELDERLY PATIENTS WITH ADVANCED LUNG CANCER

    Article • Journal of the American Geriatrics Society, February 2006, Wiley

    Dr Hiroshi Kubo

  117. Randomized Phase II Trial Comparing Nitroglycerin Plus Vinorelbine and Cisplatin With Vinorelbine and Cisplatin Alone in Previously Untreated Stage IIIB/IV Non–Small-Cell Lung Cancer

    Article • Journal of Clinical Oncology, February 2006, American Society of Clinical Oncology (ASCO)

    Dr Hiroshi Kubo

  118. NEUTROPHILS IN A PATIENT WITH JOB'S SYNDROME ARE LESS VISCOELASTIC THAN THOSE IN NORMAL SUBJECTS

    Article • CHEST Journal, October 2005, Elsevier

    Dr Hiroshi Kubo

  119. Is Cell Therapy in Acute Lung Injury a Realistic Dream?

    Article • American Review of Respiratory Disease, October 2005, American Thoracic Society

    Dr Hiroshi Kubo

  120. Erythromycin increases bactericidal activity of surface liquid in human airway epithelial cells

    Article • AJP Lung Cellular and Molecular Physiology, October 2005, American Physiological Society

    Dr Hiroshi Kubo

  121. Anticoagulant Therapy for Idiopathic Pulmonary Fibrosis

    Article • CHEST Journal, September 2005, Elsevier

    Dr Hiroshi Kubo

  122. Interleukin-1β Gene Polymorphisms Associated With COPD

    Article • CHEST Journal, August 2005, Elsevier

    Dr Hiroshi Kubo

  123. Increased circulating endothelial progenitor cells in patients with bacterial pneumonia: evidence that bone marrow derived cells contribute to lung repair

    Article • Thorax, May 2005, BMJ

    Dr Hiroshi Kubo

  124. Association of susceptibility to the development of lung adenocarcinoma with the heme oxygenase-1 gene promoter polymorphism

    Article • Human Genetics, February 2005, Springer Science + Business Media

    Dr Hiroshi Kubo

  125. The proton pump inhibitor lansoprazole inhibits rhinovirus infection in cultured human tracheal epithelial cells

    Article • European Journal of Pharmacology, February 2005, Elsevier

    Dr Hiroshi Kubo

  126. Medical Treatments and Cares for Geriatric Syndrome: New Strategies Learned from Frail Elderly

    Article • The Tohoku Journal of Experimental Medicine, January 2005, Tohoku University Medical Press

    Dr Hiroshi Kubo

  127. Inflammatory and Bronchospastic Factors in Asthma Exacerbations Caused by Upper Respiratory Tract Infections

    Article • The Tohoku Journal of Experimental Medicine, January 2005, Tohoku University Medical Press

    Dr Hiroshi Kubo

  128. Tissue Repair and Regeneration after Lung Injury: The Role of Bone Marrow —Derived Cells

    Article • THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA, January 2005, Japan Society for Clinical Anesthesia

    Dr Hiroshi Kubo

  129. Hepatocyte growth factor induces angiogenesis in injured lungs through mobilizing endothelial progenitor cells

    Article • Biochemical and Biophysical Research Communications, November 2004, Elsevier

    Dr Hiroshi Kubo

  130. Interferon-γ: a key contributor to hyperoxia-induced lung injury in mice

    Article • AJP Lung Cellular and Molecular Physiology, November 2004, American Physiological Society

    Dr Hiroshi Kubo

  131. Effects of carbenoxolone on alveolar fluid clearance and lung inflammation in the rat

    Article • Critical Care Medicine, September 2004, Wolters Kluwer Health

    Dr Hiroshi Kubo

  132. ARTERIAL CARBOXYHEMOGLOBIN CONCENTRATIONS IN ELDERLY PATIENTS WITH OPERABLE NON‐SMALL CELL LUNG CANCER

    Article • Journal of the American Geriatrics Society, August 2004, Wiley

    Dr Hiroshi Kubo

  133. Clinical significance of heparanase activity in primary resected non-small cell lung cancer

    Article • Lung Cancer, August 2004, Elsevier

    Dr Hiroshi Kubo

  134. A new therapy for Alzheimer's disease

    Article • Geriatrics and Gerontology International, June 2004, Wiley

    Dr Hiroshi Kubo

  135. Enhancement of the endotoxin recognition pathway by ventilation with a large tidal volume in rabbits

    Article • AJP Lung Cellular and Molecular Physiology, June 2004, American Physiological Society

    Dr Hiroshi Kubo

  136. Effects of antiplatelet agents on pulmonary haemodynamic response to fMLP in endotoxin primed rats

    Article • Thorax, January 2004, BMJ

    Dr Hiroshi Kubo

  137. Bone marrow‐derived cells contribute to lung regeneration after elastase‐induced pulmonary emphysema

    Article • FEBS Letters, December 2003, Wiley

    Dr Hiroshi Kubo

  138. Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines

    Article • Blood, September 2003, American Society of Hematology

    Dr Hiroshi Kubo

  139. Effects of rewarming on nuclear factor-??B and interleukin 8 expression in cold-preserved alveolar epithelial cells

    Article • Transplantation, July 2003, Wolters Kluwer Health

    Dr Hiroshi Kubo

  140. Dexamethasone Upregulates 11β-Hydroxysteroid Dehydrogenase Type 2 in BEAS-2B Cells

    Article • American Review of Respiratory Disease, May 2003, American Thoracic Society

    Dr Hiroshi Kubo

  141. Single dexamethasone injection increases alveolar fluid clearance in adult rats*

    Article • Critical Care Medicine, April 2003, Wolters Kluwer Health

    Dr Hiroshi Kubo

  142. Early Changes in Alveolar Fluid Clearance by Nitric Oxide after Endotoxin Instillation in Rats

    Article • American Review of Respiratory Disease, January 2003, American Thoracic Society

    Dr Hiroshi Kubo

  143. Care for Older People

    Article • Internal Medicine, January 2003, Japanese Society of Internal Medicine

    Dr Hiroshi Kubo

  144. Prevention of respiratory infections in the elderly

    Article • Geriatrics and Gerontology International, September 2002, Wiley

    Dr Hiroshi Kubo

  145. Endothelial signal transduction system enhances neutrophil‐induced pulmonary vascular permeability

    Article • European Respiratory Journal, March 2000, European Respiratory Society (ERS)

    Dr Hiroshi Kubo

  146. Superoxide possibly produced in endothelial cells mediates the neutrophil-induced lung injury

    Article • The Annals of Thoracic Surgery, February 2000, Elsevier

    Dr Hiroshi Kubo

  147. Superoxide anion mediates pulmonary vascular permeability caused by neutrophils in cardiopulmonary bypass

    Article • Surgery Today, August 1999, Springer Science + Business Media

    Dr Hiroshi Kubo

  148. Activated Alveolar Macrophage-Derived Nitric Oxide Predicts the Development of Lung Damage After Marrow Transplantation in Mice

    Article • CHEST Journal, July 1999, Elsevier

    Dr Hiroshi Kubo

  149. Stimulated Neutrophils Evoke Signal Transduction to Increase Vascular Permeability in Rat Lungs.

    Article • The Tohoku Journal of Experimental Medicine, January 1999, Tohoku University Medical Press

    Dr Hiroshi Kubo

  150. L- and P-Selectin and CD11/CD18 in Intracapillary Neutrophil Sequestration in Rabbit Lungs

    Article • American Review of Respiratory Disease, January 1999, American Thoracic Society

    Dr Hiroshi Kubo

  151. Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

    Article • Journal of Experimental Medicine, October 1997, Rockefeller University Press

    Dr Hiroshi Kubo

  152. Cyclooxygenase Metabolites Possibly Produced by Endothelial Cells Mediate the Lung Injury Caused by Mechanically Stimulated Leukocytes.

    Article • The Tohoku Journal of Experimental Medicine, January 1997, Tohoku University Medical Press

    Dr Hiroshi Kubo

  153. Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase.

    Article • Journal of Clinical Investigation, June 1996, American Society for Clinical Investigation

    Dr Hiroshi Kubo

  154. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice

    Article • Journal of Experimental Medicine, May 1996, Rockefeller University Press

    Dr Hiroshi Kubo

  155. Adhesion Molecule CD18 on Polymorphonuclear Cells Correlates to the Lung Injury Caused by Continuous Infusion of Endotoxin in Sheep.

    Article • The Tohoku Journal of Experimental Medicine, January 1995, Tohoku University Medical Press

    Dr Hiroshi Kubo

  156. Stimulation of Pulmonary Intravascular Macrophages Increases Microvascular Permeability in Awake Sheep.

    Article • The Tohoku Journal of Experimental Medicine, January 1993, Tohoku University Medical Press

    Dr Hiroshi Kubo

  157. Lung function in operated lung after lobectomy.

    Article • January 1991, Japanese Association for Chest Surgery

    Dr Hiroshi Kubo

  158. 肥満患者肺切除例の急性期術後合併症に関する検討

    Article • January 1990, Japanese Association for Chest Surgery

    Dr Hiroshi Kubo