All Stories

  1. Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease

    Article • Journal of Alzheimer s Disease, October 2023, IOS Press

    Hieronim Jakubowski Jakubowski

  2. Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1‐dependent epigenetic regulation of mTOR in cystathionine β‐synthase‐deficient mice

    Article • Journal of Inherited Metabolic Disease, July 2023, Wiley

    Hieronim Jakubowski Jakubowski

  3. Homocysteine Metabolites Impair the Phf8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of PHF8-targeting miR-22-3p and miR-1229-3p in Human Vascular Endothelial Cells

    Article • June 2023, Cold Spring Harbor Laboratory Press

    Hieronim Jakubowski Jakubowski

  4. Proteomic Exploration of Paraoxonase 1 Function in Health and Disease

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Hieronim Jakubowski Jakubowski

  5. Homocysteine Metabolites Inhibit Autophagy and Elevate Amyloid Beta by Impairing Phf8/H4K20me1-dependent Epigenetic Regulation of mTOR in Cystathionine β-Synthase-Deficient Mice

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Hieronim Jakubowski Jakubowski

  6. Depletion of bleomycin hydrolase (Blmh) downregulates histone demethylase Phf8, impairs mTOR signaling/autophagy, accelerates amyloid beta accumulation, and induces neurological deficits in mice

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Hieronim Jakubowski Jakubowski

  7. Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice

    Article • Cells, February 2023, MDPI AG

    Hieronim Jakubowski Jakubowski

  8. Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease

    Article • PLoS ONE, October 2022, PLOS

    Hieronim Jakubowski Jakubowski

  9. Cystathionine β‐synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice

    Article • The FASEB Journal, September 2022, Wiley

    Hieronim Jakubowski Jakubowski

  10. Homocysteine thiolactone contributes to a prognostic value of fibrin clot structure/function in coronary artery disease patients

    Article • July 2022, Cold Spring Harbor Laboratory Press

    Hieronim Jakubowski Jakubowski

  11. Cystathionine β-synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice

    Article • July 2022, Cold Spring Harbor Laboratory Press

    Hieronim Jakubowski Jakubowski

  12. Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson’s Disease

    Article • Nutrients, May 2022, MDPI AG

    Hieronim Jakubowski Jakubowski

  13. COVID-19 and One-Carbon Metabolism

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Hieronim Jakubowski Jakubowski

  14. B Vitamins Prevent Iron-Associated Brain Atrophy and Domain-Specific Effects of Iron, Copper, Aluminum, and Silicon on Cognition in Mild Cognitive Impairment

    Article • Journal of Alzheimer s Disease, November 2021, IOS Press

    Prof. Marcin Frankowski, Hieronim Jakubowski Jakubowski

  15. Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment

    Article • Journal of Alzheimer s Disease, June 2021, IOS Press

    Hieronim Jakubowski Jakubowski, Prof. Marcin Frankowski

  16. Changes in redox plasma proteome of Pon1−/− mice are exacerbated by a hyperhomocysteinemic diet

    Article • Free Radical Biology and Medicine, June 2021, Elsevier

    Hieronim Jakubowski Jakubowski

  17. Proteome-Wide Analysis of Protein Lysine N-Homocysteinylation in Saccharomyces cerevisiae

    Article • Journal of Proteome Research, April 2021, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  18. Anti‐ N ‐homocysteine‐protein autoantibodies are associated with impaired cognition

    Article • Alzheimer s & Dementia Translational Research & Clinical Interventions, January 2021, Wiley

    Hieronim Jakubowski Jakubowski

  19. Genetic Attenuation of Paraoxonase 1 Activity Induces Proatherogenic Changes in Plasma Proteomes of Mice and Humans

    Article • Antioxidants, November 2020, MDPI AG

    Hieronim Jakubowski Jakubowski

  20. Telomere Length and mtDNA Copy Number in Human Cystathionine β-synthase Deficiency

    Article • Free Radical Biology and Medicine, August 2020, Elsevier

    Hieronim Jakubowski Jakubowski

  21. Cystathionine β-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs−/− mice and thrombosis-prone CBS−/− humans

    Article • Scientific Reports, July 2020, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  22. Quantification of homocysteine thiolactone in human saliva and urine by gas chromatography-mass spectrometry

    Article • Journal of Chromatography B, July 2020, Elsevier

    Hieronim Jakubowski Jakubowski

  23. Copper, heart disease and homocysteine thiolactone

    Article • Journal of Internal Medicine, May 2020, Wiley

    Hieronim Jakubowski Jakubowski

  24. The Cbs Locus Affects the Expression of Senescence Markers and mtDNA Copy Number, but not Telomere Dynamics in Mice

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    Hieronim Jakubowski Jakubowski

  25. The Multispecies Probiotic Effectively Reduces Homocysteine Concentration in Obese Women: A Randomized Double-Blind Placebo-Controlled Study

    Article • Journal of Clinical Medicine, April 2020, MDPI AG

    Hieronim Jakubowski Jakubowski

  26. Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice

    Article • Journal of Investigative Dermatology, August 2019, Elsevier

    Hieronim Jakubowski Jakubowski

  27. Dysregulation of Epigenetic Mechanisms of Gene Expression in the Pathologies of Hyperhomocysteinemia

    Article • International Journal of Molecular Sciences, June 2019, MDPI AG

    Hieronim Jakubowski Jakubowski

  28. Serum Proteome Alterations in Human Cystathionine β-Synthase Deficiency and Ischemic Stroke Subtypes

    Article • International Journal of Molecular Sciences, June 2019, MDPI AG

    Hieronim Jakubowski Jakubowski

  29. Sex affects N-homocysteinylation at lysine residue 212 of albumin in mice

    Article • Scientific Reports, February 2019, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  30. Homocysteine Modification in Protein Structure/Function and Human Disease

    Article • Physiological Reviews, January 2019, American Physiological Society

    Hieronim Jakubowski Jakubowski

  31. Protein N-Homocysteinylation and Colorectal Cancer

    Article • Trends in Cancer, January 2019, Elsevier

    Hieronim Jakubowski Jakubowski

  32. Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice

    Article • International Journal of Genomics, September 2018, Hindawi Publishing Corporation

    Hieronim Jakubowski Jakubowski

  33. Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial

    Article • Journal of Internal Medicine, September 2018, Wiley

    Hieronim Jakubowski Jakubowski

  34. Garlic extract favorably modifies markers of endothelial function in obese patients –randomized double blind placebo-controlled nutritional intervention

    Article • Biomedicine & Pharmacotherapy, June 2018, Elsevier

    Hieronim Jakubowski Jakubowski

  35. Genetic variation in paraoxonase 1 and homocysteine thiolactone accumulation in humans

    Article • The FASEB Journal, May 2018, Federation of American Societies For Experimental Biology (FASEB)

    Hieronim Jakubowski Jakubowski, Rafał Głowacki, Joanna Perła-Kajan

  36. Demethylation of methionine and keratin damage in human hair

    Article • Amino Acids, February 2018, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  37. Homocysteine Editing, Thioester Chemistry, Coenzyme A, and the Origin of Coded Peptide Synthesis †

    Article • Life, February 2017, MDPI AG

    Hieronim Jakubowski Jakubowski

  38. Simultaneous Determination of Methionine and Homocysteine by on-column derivatization with o -phtaldialdehyde

    Article • Talanta, December 2016, Elsevier

    Hieronim Jakubowski Jakubowski

  39. The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice

    Article • The FASEB Journal, October 2016, Federation of American Societies For Experimental Biology (FASEB)

    Dr. khoosheh khayati, Hieronim Jakubowski Jakubowski

  40. Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs

    Article • PLoS Pathogens, October 2016, PLOS

    Hieronim Jakubowski Jakubowski

  41. Quantification of urinary S- and N-homocysteinylated protein and homocysteine-thiolactone in mice

    Article • Analytical Biochemistry, September 2016, Elsevier

    Hieronim Jakubowski Jakubowski

  42. Connective tissue damage by homocysteine

    Article • The FASEB Journal, August 2016, Federation of American Societies For Experimental Biology (FASEB)

    Hieronim Jakubowski Jakubowski, Marta Rusek

  43. Effects of endurance and endurance–strength exercise on biochemical parameters of liver function in women with abdominal obesity

    Article • Biomedicine & Pharmacotherapy, May 2016, Elsevier

    Hieronim Jakubowski Jakubowski

  44. Aminoacyl-tRNA synthetases and the evolution of coded peptide synthesis: the Thioester World

    Article • FEBS Letters, February 2016, Wiley

    Hieronim Jakubowski Jakubowski

  45. Quantification of homocysteine and cysteine by derivatization with pyridoxal 5'-phosphate and hydrophilic interaction liquid chromatography

    Article • Analytical and Bioanalytical Chemistry, January 2016, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  46. l -Arginine and vitamin C attenuate pro-atherogenic effects of high-fat diet on biomarkers of endothelial dysfunction in rats

    Article • Biomedicine & Pharmacotherapy, December 2015, Elsevier

    Hieronim Jakubowski Jakubowski

  47. Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes in gene expression in human vascular endothelial cells

    Article • Amino Acids, March 2015, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  48. Paraoxonase 1 deficiency and hyperhomocysteinemia alter the expression of mouse kidney proteins involved in renal disease

    Article • Molecular Genetics and Metabolism, November 2014, Elsevier

    Hieronim Jakubowski Jakubowski

  49. The influence of selected antihypertensive drugs on zinc, copper, and iron status in spontaneously hypertensive rats

    Article • European Journal of Pharmacology, September 2014, Elsevier

    Hieronim Jakubowski Jakubowski

  50. Labeled EF-Tus for Rapid Kinetic Studies of Pretranslocation Complex Formation

    Article • ACS Chemical Biology, August 2014, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  51. Inactivation of the Paraoxonase 1 Gene Affects the Expression of Mouse Brain Proteins Involved in Neurodegeneration

    Article • Journal of Alzheimer s Disease, August 2014, IOS Press

    Hieronim Jakubowski Jakubowski

  52. Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease

    Article • Molecular Genetics and Metabolism, August 2014, Elsevier

    Hieronim Jakubowski Jakubowski

  53. Hyperhomocysteinemia and Bleomycin Hydrolase Modulate the Expression of Mouse Brain Proteins Involved in Neurodegeneration

    Article • Journal of Alzheimer s Disease, April 2014, IOS Press

    Hieronim Jakubowski Jakubowski

  54. Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis

    Article • Amino Acids, March 2014, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  55. Identification of N-homocysteinylation sites in plasma proteins

    Article • Amino Acids, November 2013, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  56. Effects of betaine on body composition, performance, and homocysteine thiolactone

    Article • Journal of the International Society of Sports Nutrition, August 2013, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  57. Correction

    Article • Circulation, April 2013, Wolters Kluwer Health

    Hieronim Jakubowski Jakubowski

  58. The Mechanism and Consequences of Homocysteine Incorporation Into Protein in Humans

    Article • Phosphorus Sulfur and Silicon and the Related Elements, April 2013, Taylor & Francis

    Hieronim Jakubowski Jakubowski

  59. Design and properties of efficient tRNA:EF-Tu FRET system for studies of ribosomal translation

    Article • Protein Engineering Design and Selection, February 2013, Oxford University Press (OUP)

    Hieronim Jakubowski Jakubowski

  60. Homocysteine in Protein Structure/Function and Human Disease

    Article • January 2013, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  61. N-homocysteinylation of ovine prion protein induces amyloid-like transformation

    Article • Archives of Biochemistry and Biophysics, October 2012, Elsevier

    Hieronim Jakubowski Jakubowski

  62. Paraoxonase 1 and homocysteine metabolism

    Article • Amino Acids, May 2012, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  63. Metabolism and Neurotoxicity of Homocysteine Thiolactone in Mice: Evidence for a Protective Role of Paraoxonase 1

    Article • Journal of Alzheimer s Disease, May 2012, IOS Press

    Hieronim Jakubowski Jakubowski

  64. Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase

    Article • Amino Acids, January 2012, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  65. Plasma total homocysteine is a determinant of carotid intima-media thickness and circulating endothelial progenitor cells in patients with newly diagnosed hypertension

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2012, De Gruyter

    Hieronim Jakubowski Jakubowski

  66. Quality control in tRNA charging

    Article • Wiley Interdisciplinary Reviews - RNA, November 2011, Wiley

    Hieronim Jakubowski Jakubowski

  67. Aggregation and structural changes of αS1-, β- and κ-caseins induced by homocysteinylation

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, October 2011, Elsevier

    Hieronim Jakubowski Jakubowski

  68. Cation exchange HPLC analysis of desmosines in elastin hydrolysates

    Article • Analytical and Bioanalytical Chemistry, September 2011, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  69. Analysis of site-specific N-homocysteinylation of human serum albumin in vitro and in vivo using MALDI-ToF and LC-MS/MS mass spectrometry

    Article • Journal of Proteomics, June 2011, Elsevier

    Hieronim Jakubowski Jakubowski

  70. Chemical Biology of Homocysteine Thiolactone and Related Metabolites

    Article • January 2011, Elsevier

    Hieronim Jakubowski Jakubowski

  71. Elevated concentrations of Nɛ-homocysteinyl-lysine isopeptide in acute myocardial infarction: links with ADMA formation

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2011, De Gruyter

    Hieronim Jakubowski Jakubowski

  72. Direct monitoring of albumin lysine-525 N-homocysteinylation in human serum by liquid chromatography/mass spectrometry

    Article • Analytical Biochemistry, October 2010, Elsevier

    Hieronim Jakubowski Jakubowski

  73. Identification and origin of Nε-homocysteinyl-lysine isopeptide in humans and mice

    Article • Amino Acids, May 2010, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  74. Reduced Homocysteine-Thiolactonase Activity in Alzheimer's Disease

    Article • Journal of Alzheimer s Disease, March 2010, IOS Press

    Hieronim Jakubowski Jakubowski

  75. An on-column derivatization method for the determination of homocysteine-thiolactone and protein N-linked homocysteine

    Article • Amino Acids, March 2010, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  76. On-column derivatization with o-phthaldialdehyde for fast determination of homocysteine in human urine

    Article • Analytical and Bioanalytical Chemistry, February 2010, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  77. Properties of Escherichia coli EF-Tu mutants designed for fluorescence resonance energy transfer from tRNA molecules

    Article • Protein Engineering Design and Selection, January 2010, Oxford University Press (OUP)

    Hieronim Jakubowski Jakubowski

  78. The Role of Paraoxonase 1 in the Detoxification of Homocysteine Thiolactone

    Article • November 2009, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  79. Modulation of paraoxonase 1 and protein N-homocysteinylation by leptin and the synthetic liver X receptor agonist T0901317 in the rat

    Article • Journal of Endocrinology, November 2009, Bioscientifica

    Hieronim Jakubowski Jakubowski

  80. Paraoxonase 1 protects against protein N-homocysteinylation in humans

    Article • The FASEB Journal, October 2009, Federation of American Societies For Experimental Biology (FASEB)

    Hieronim Jakubowski Jakubowski

  81. Homocysteine editing and growth inhibition in Escherichia coli

    Article • Microbiology, April 2009, Society for General Microbiology

    Hieronim Jakubowski Jakubowski

  82. Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice

    Article • The FASEB Journal, February 2009, Federation of American Societies For Experimental Biology (FASEB)

    Hieronim Jakubowski Jakubowski

  83. Role of homocysteine in aortic calcification and osteogenic cell differentiation

    Article • Atherosclerosis, February 2009, Elsevier

    Hieronim Jakubowski Jakubowski

  84. Immunohistochemical detection of N-homocysteinylated proteins in humans and mice

    Article • Biomedicine & Pharmacotherapy, September 2008, Elsevier

    Hieronim Jakubowski Jakubowski

  85. New method for the determination of protein N-linked homocysteine

    Article • Analytical Biochemistry, September 2008, Elsevier

    Hieronim Jakubowski Jakubowski

  86. Mutations in cystathionine  -synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans

    Article • The FASEB Journal, August 2008, Federation of American Societies For Experimental Biology (FASEB)

    Hieronim Jakubowski Jakubowski

  87. Plasma homocysteine is a determinant of tissue necrosis factor-α in hypertensive patients

    Article • Biomedicine & Pharmacotherapy, July 2008, Elsevier

    Hieronim Jakubowski Jakubowski

  88. Fluorescence enhancement on silver nanostructures: studies of components of ribosomal translation in vitro

    Article • February 2008, SPIE

    Hieronim Jakubowski Jakubowski

  89. Facile syntheses of [35S]homocysteine-thiolactone, [35S]homocystine, [35S]homocysteine, and [S-nitroso-35S]homocysteine

    Article • Analytical Biochemistry, November 2007, Elsevier

    Hieronim Jakubowski Jakubowski

  90. Differential Regulation of Homocysteine Transport in Vascular Endothelial and Smooth Muscle Cells

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2007, Wolters Kluwer Health

    Hieronim Jakubowski Jakubowski

  91. Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency

    Article • Molecular Genetics and Metabolism, June 2007, Elsevier

    Hieronim Jakubowski Jakubowski

  92. Modification by Homocysteine Thiolactone Affects Redox Status of Cytochromec

    Article • Biochemistry, May 2007, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  93. Mutations in methylenetetrahydrofolate reductase or cystathionine  -syntase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice

    Article • The FASEB Journal, February 2007, Federation of American Societies For Experimental Biology (FASEB)

    Hieronim Jakubowski Jakubowski

  94. Mechanisms of homocysteine toxicity in humans

    Article • Amino Acids, February 2007, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  95. The molecular basis of homocysteine thiolactone-mediated vascular disease

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2007, De Gruyter

    Hieronim Jakubowski Jakubowski

  96. Mechanism of the Condensation of Homocysteine Thiolactone with Aldehydes

    Article • Chemistry - A European Journal, October 2006, Wiley

    Hieronim Jakubowski Jakubowski

  97. Letter by Undas and Jakubowski Regarding Article, “Relationship Between Homocysteine and Mortality in Chronic Kidney Disease”

    Article • Circulation, October 2006, Wolters Kluwer Health

    Hieronim Jakubowski Jakubowski

  98. Protective Mechanisms against Homocysteine Toxicity

    Article • Journal of Biological Chemistry, June 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  99. Plasma Homocysteine Affects Fibrin Clot Permeability and Resistance to Lysis in Human Subjects

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2006, Wolters Kluwer Health

    Hieronim Jakubowski Jakubowski

  100. Synergistic, Random Sequential Binding of Substrates in Cobalamin-Independent Methionine Synthase†

    Article • Biochemistry, April 2006, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  101. Folic acid administration and antibodies against homocysteinylated proteins in subjects with hyperhomocysteinemia

    Article • Thrombosis and Haemostasis, January 2006, Thieme Publishing Group

    Hieronim Jakubowski Jakubowski

  102. The determination of homocysteine–thiolactone in human plasma

    Article • Analytical Biochemistry, February 2005, Elsevier

    Hieronim Jakubowski Jakubowski

  103. Urinary Excretion of Homocysteine-Thiolactone in Humans

    Article • Clinical Chemistry, February 2005, AACC

    Hieronim Jakubowski Jakubowski

  104. Anti-N-homocysteinylated protein autoantibodies and cardiovascular disease

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2005, De Gruyter

    Hieronim Jakubowski Jakubowski

  105. Antibodies to N-homocysteinylated albumin as a marker for earlyonset coronary artery disease in men

    Article • Thrombosis and Haemostasis, January 2005, Thieme Publishing Group

    Hieronim Jakubowski Jakubowski

  106. The effects of age and hyperhomocysteinemia on the redox forms of plasma thiols

    Article • Journal of Laboratory and Clinical Medicine, November 2004, Elsevier

    Hieronim Jakubowski Jakubowski

  107. Purification of antibodies against N-homocysteinylated proteins by affinity chromatography on Nω-homocysteinyl-aminohexyl-Agarose

    Article • Journal of Chromatography B, August 2004, Elsevier

    Hieronim Jakubowski Jakubowski

  108. Autoantibodies Against N -Homocysteinylated Proteins in Humans

    Article • Stroke, June 2004, Wolters Kluwer Health

    Hieronim Jakubowski Jakubowski

  109. Molecular basis of homocysteine toxicity in humans

    Article • Cellular and Molecular Life Sciences, February 2004, Springer Science + Business Media

    Hieronim Jakubowski Jakubowski

  110. Cross-talk between Cys34and Lysine Residues in Human Serum Albumin Revealed byN-Homocysteinylation

    Article • Journal of Biological Chemistry, December 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  111. On the health benefits of Allium sp.

    Article • Nutrition, February 2003, Elsevier

    Hieronim Jakubowski Jakubowski

  112. Homocysteine-Thiolactone and S-Nitroso-Homocysteine Mediate Incorporation of Homocysteine into Protein in Humans

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2003, De Gruyter

    Hieronim Jakubowski Jakubowski

  113. Metabolism of Homocysteine-thiolactone in Plants

    Article • Journal of Biological Chemistry, December 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  114. Genomic Association/Linkage of Sodium Lithium Countertransport in CEPH Pedigrees

    Article • Hypertension, November 2002, Wolters Kluwer Health

    Hieronim Jakubowski Jakubowski

  115. The determination of homocysteine-thiolactone in biological samples

    Article • Analytical Biochemistry, September 2002, Elsevier

    Hieronim Jakubowski Jakubowski

  116. Homocysteine Is a Protein Amino Acid in Humans

    Article • Journal of Biological Chemistry, July 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  117. Protein N-homocysteinylation: implications for atherosclerosis

    Article • Biomedicine & Pharmacotherapy, October 2001, Elsevier

    Hieronim Jakubowski Jakubowski

  118. Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions

    Article • Journal of Molecular Biology, August 2001, Elsevier

    Hieronim Jakubowski Jakubowski

  119. Genetic determinants of homocysteine thiolactonase activity in humans: implications for atherosclerosis

    Article • FEBS Letters, February 2001, Wiley

    Hieronim Jakubowski Jakubowski

  120. Amino Acid Selectivity in the Aminoacylation of Coenzyme A and RNA Minihelices by Aminoacyl-tRNA Synthetases

    Article • Journal of Biological Chemistry, September 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  121. Homocysteine Thiolactone and Protein Homocysteinylation in Human Endothelial Cells

    Article • Circulation Research, July 2000, Wolters Kluwer Health

    Hieronim Jakubowski Jakubowski

  122. Translational Incorporation ofS-Nitrosohomocysteine into Protein

    Article • Journal of Biological Chemistry, May 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  123. Calcium-dependent Human Serum Homocysteine Thiolactone Hydrolase

    Article • Journal of Biological Chemistry, February 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  124. Misacylation of tRNALyswith Noncognate Amino Acids by Lysyl-tRNA Synthetase†

    Article • Biochemistry, June 1999, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  125. Aminoacylation of Coenzyme A and Pantetheine by Aminoacyl-tRNA Synthetases:  Possible Link between Noncoded and Coded Peptide Synthesis†

    Article • Biochemistry, April 1998, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  126. Aminoacyl Thioester Chemistry of Class II Aminoacyl-tRNA Synthetases†

    Article • Biochemistry, September 1997, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  127. Proofreading in trans by an aminoacyl-tRNA synthetase: a model for single site editing by isoleucyl-tRNA synthetase

    Article • Nucleic Acids Research, July 1996, Oxford University Press (OUP)

    Hieronim Jakubowski Jakubowski

  128. The Synthetic/Editing Active Site of an Aminoacyl-tRNA Synthetase:  Evidence for Binding of Thiols in the Editing Subsite†

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  129. Evidence that Uncharged tRNA Can Inhibit a Programmed Translational Frameshift inEscherichia coli

    Article • Journal of Molecular Biology, August 1995, Elsevier

    Hieronim Jakubowski Jakubowski

  130. Proofreadingin Vivo

    Article • Journal of Biological Chemistry, July 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Hieronim Jakubowski Jakubowski

  131. Synthesis of cysteine-containing dipeptides by aminpacyl-tRNAsynthetases

    Article • Nucleic Acids Research, January 1995, Oxford University Press (OUP)

    Hieronim Jakubowski Jakubowski

  132. Role of carboxy-terminal region in proofreading function of methionyl-tRNA synthetase in Escherichia coli

    Article • Biochemistry, September 1994, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  133. Editing function ofEscherichia coli cysteinyl-tRNA synthetase: cyclization of cysteine to cysteine thiolactone

    Article • Nucleic Acids Research, January 1994, Oxford University Press (OUP)

    Hieronim Jakubowski Jakubowski

  134. Synthesis of homocysteine thiolactone by methionyl-tRNA synthetase in cultured mammalian cells

    Article • FEBS Letters, February 1993, Wiley

    Hieronim Jakubowski Jakubowski

  135. Role of the metF and metJ genes on the vitamin B12 regulation of methionine gene expression: Involvement of N5-methyltetrahydrofolic acid

    Article • Biochemical and Biophysical Research Communications, January 1992, Elsevier

    Hieronim Jakubowski Jakubowski

  136. Relationship between protein synthesis and concentrations of charged and uncharged tRNATrp in Escherichia coli.

    Article • Proceedings of the National Academy of Sciences, February 1990, Proceedings of the National Academy of Sciences

    Hieronim Jakubowski Jakubowski

  137. Negative correlation between the abundance of Escherichia coli aminoacyl-tRNA families and their affinities for elongation factor Tu-GTP

    Article • Journal of Theoretical Biology, August 1988, Elsevier

    Hieronim Jakubowski Jakubowski

  138. Synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate (AppppA) from adenosine 5'-phosphosulfate and adenosine 5'-triphosphate catalyzed by yeast AppppA phosphorylase

    Article • Biochemistry, April 1988, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  139. Phosphonate analogs of diadenosine 5',5'''-P1,P4-tetraphosphate as substrates or inhibitors of prokaryotic and eukaryotic enzymes degrading dinucloside tetraphosphates

    Article • Biochemistry, June 1987, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  140. Adenosylhomocysteinase from yellow lupine

    Article • January 1987, Elsevier

    Hieronim Jakubowski Jakubowski

  141. Control of RNA and protein synthesis by the concentration of Trp-tRNATrp in Escherichia coli infected with bacteriophage MS2

    Article • Journal of Molecular Biology, August 1983, Elsevier

    Hieronim Jakubowski Jakubowski

  142. Substrate specificity of S-Adenosylhomocysteinase

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, January 1983, Elsevier

    Hieronim Jakubowski Jakubowski

  143. The mechanism of inhibition of valyl-tRNA synthetase by S-adenosylhomocysteine

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, December 1982, Elsevier

    Hieronim Jakubowski Jakubowski

  144. S-Adenosylhomocysteinase from yellow lupine seeds: stoichiometry and reactions of the enzyme.cntdot.adenosine complex

    Article • Biochemistry, November 1981, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  145. Alternative pathways for editing non-cognate amino acids by aminoacyl-tRNA synthetases

    Article • Nucleic Acids Research, January 1981, Oxford University Press (OUP)

    Hieronim Jakubowski Jakubowski

  146. Valyl-tRNA synthetase from yellow lupin seeds: hydrolysis of the enzyme-bound noncognate aminoacyl adenylate as a possible mechanism of increasing specificity of the aminoacyl-tRNA synthetase

    Article • Biochemistry, October 1980, American Chemical Society (ACS)

    Hieronim Jakubowski Jakubowski

  147. Polyamines and yellow lupin aminoacyl-tRNA synthetases

    Article • FEBS Letters, January 1980, Wiley

    Hieronim Jakubowski Jakubowski

  148. A role for protein-protein interactions in the maintenance of active forms of aminoacyl-tRNA synthetases

    Article • FEBS Letters, July 1979, Wiley

    Hieronim Jakubowski Jakubowski

  149. Yellow lupin (Lupinus luteus) aminoacyl-tRNA synthetases

    Article • Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, December 1978, Elsevier

    Hieronim Jakubowski Jakubowski

  150. Valyl-tRNA synthetase from yellow lupin seeds

    Article • FEBS Letters, November 1978, Wiley

    Hieronim Jakubowski Jakubowski

  151. Adenosylhomocysteinase:Adenosine complex

    Article • Biochemical and Biophysical Research Communications, October 1978, Elsevier

    Hieronim Jakubowski Jakubowski

  152. The mechanism of the aminoacylation of transfer ribonucleic acid The kinetics and stoichiometry of the lysis of aminoacyl-tRNA

    Article • Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, October 1978, Elsevier

    Hieronim Jakubowski Jakubowski

  153. Incomplete aminoacylation of tRNALeu catalyzed in vitro by leucyl-tRNA synthetase from Escherichia coli B

    Article • Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, April 1978, Elsevier

    Hieronim Jakubowski Jakubowski

  154. The determination of aminoacyl adenylate by thin-layer chromatography

    Article • Analytical Biochemistry, September 1977, Elsevier

    Hieronim Jakubowski Jakubowski

  155. Use of ω-aminohexyl-sepharose in the fractionation of escherichia coli B aminoacyl-tRNA synthetases

    Article • Journal of Chromatography A, September 1977, Elsevier

    Hieronim Jakubowski Jakubowski

  156. Fractionation of plant aminoacyl-tRNA synthetases on tRNA-sepharose columns

    Article • Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, October 1975, Elsevier

    Hieronim Jakubowski Jakubowski

  157. The Plant Aminoacyl-tRNA Synthetases. Purification and Characterization of Valyl-tRNA, Tryptophanyl-tRNA and Seryl-tRNA Synthetases from Yellow-Lupin Seeds

    Article • European Journal of Biochemistry, March 1975, Wiley

    Hieronim Jakubowski Jakubowski

  158. Transfer RNA methyltransferases from yellow lupin seeds: purification and properties

    Article • Nucleic Acids Research, January 1975, Oxford University Press (OUP)

    Hieronim Jakubowski Jakubowski

  159. ω-Aminohexyl-Sepharose 4B, a new support for tRNA fractionation

    Article • Journal of Chromatography A, January 1975, Elsevier

    Hieronim Jakubowski Jakubowski

  160. Chromatography of plant aminoacyl-tRNA synthetases on ω-aminoalkyl sepharose columns

    Article • FEBS Letters, August 1973, Wiley

    Hieronim Jakubowski Jakubowski

  161. Homocysteine Metabolism and Pathological Implications: The Homocysteine Thiolactone Hypothesis of Vascular Disease

    Article • Wiley

    Hieronim Jakubowski Jakubowski