Hieronim Jakubowski Jakubowski

Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and ...

• Journal of Investigative Dermatology
• August 2019

Dysregulation of Epigenetic Mechanisms of Gene Expression in the Pathologies of Hyperho...

• International Journal of Molecular Sciences
• June 2019

Serum Proteome Alterations in Human Cystathionine β-Synthase Deficiency and Ischemic St...

• International Journal of Molecular Sciences
• June 2019

Sex affects N-homocysteinylation at lysine residue 212 of albumin in mice

• Scientific Reports
• February 2019

Homocysteine Modification in Protein Structure/Function and Human Disease

• Physiological Reviews
• January 2019

Protein N-Homocysteinylation and Colorectal Cancer

• Trends in Cancer
• January 2019

Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Da...

• International Journal of Genomics
• September 2018

Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarcti...

• Journal of Internal Medicine
• September 2018

Garlic extract favorably modifies markers of endothelial function in obese patients –ra...

• Biomedicine & Pharmacotherapy
• June 2018

Genetic variation in paraoxonase 1 and homocysteine thiolactone accumulation in humans

• The FASEB Journal
• May 2018

Demethylation of methionine and keratin damage in human hair

• Amino Acids
• February 2018

Homocysteine Editing, Thioester Chemistry, Coenzyme A, and the Origin of Coded Peptide...

• Life
• February 2017

Simultaneous Determination of Methionine and Homocysteine by on-column derivatization w...

• Talanta
• December 2016

The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form a...

• The FASEB Journal
• October 2016

Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs

• PLoS Pathogens
• October 2016

Quantification of urinary S- and N-homocysteinylated protein and homocysteine-thiolacto...

• Analytical Biochemistry
• September 2016

Connective tissue damage by homocysteine

• The FASEB Journal
• August 2016

Effects of endurance and endurance–strength exercise on biochemical parameters of liver...

• Biomedicine & Pharmacotherapy
• May 2016

Aminoacyl-tRNA synthetases and the evolution of coded peptide synthesis: the Thioester ...

• FEBS Letters
• February 2016

Quantification of homocysteine and cysteine by derivatization with pyridoxal 5'-phospha...

• Analytical and Bioanalytical Chemistry
• January 2016

l -Arginine and vitamin C attenuate pro-atherogenic effects of high-fat diet on biomark...

• Biomedicine & Pharmacotherapy
• December 2015

Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes...

• Amino Acids
• March 2015

Paraoxonase 1 deficiency and hyperhomocysteinemia alter the expression of mouse kidney ...

• Molecular Genetics and Metabolism
• November 2014

The influence of selected antihypertensive drugs on zinc, copper, and iron status in sp...

• European Journal of Pharmacology
• September 2014

Labeled EF-Tus for Rapid Kinetic Studies of Pretranslocation Complex Formation

• ACS Chemical Biology
• August 2014

Inactivation of the Paraoxonase 1 Gene Affects the Expression of Mouse Brain Proteins I...

• Journal of Alzheimer s Disease
• August 2014

Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the ex...

• Molecular Genetics and Metabolism
• August 2014

Hyperhomocysteinemia and Bleomycin Hydrolase Modulate the Expression of Mouse Brain Pro...

• Journal of Alzheimer s Disease
• April 2014

Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins ...

• Amino Acids
• March 2014

Identification of N-homocysteinylation sites in plasma proteins

• Amino Acids
• November 2013

Effects of betaine on body composition, performance, and homocysteine thiolactone

• Journal of the International Society of Sports Nutrition
• August 2013

Correction

• Circulation
• April 2013

The Mechanism and Consequences of Homocysteine Incorporation Into Protein in Humans

• Phosphorus Sulfur and Silicon and the Related Elements
• April 2013

Design and properties of efficient tRNA:EF-Tu FRET system for studies of ribosomal tran...

• Protein Engineering Design and Selection
• February 2013

Homocysteine in Protein Structure/Function and Human Disease

• January 2013

N-homocysteinylation of ovine prion protein induces amyloid-like transformation

• Archives of Biochemistry and Biophysics
• October 2012

Paraoxonase 1 and homocysteine metabolism

• Amino Acids
• May 2012

Metabolism and Neurotoxicity of Homocysteine Thiolactone in Mice: Evidence for a Protec...

• Journal of Alzheimer s Disease
• May 2012

Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bl...

• Amino Acids
• January 2012

Plasma total homocysteine is a determinant of carotid intima-media thickness and circul...

• Clinical Chemistry and Laboratory Medicine (CCLM)
• January 2012

Quality control in tRNA charging

• Wiley Interdisciplinary Reviews - RNA
• November 2011

Aggregation and structural changes of αS1-, β- and κ-caseins induced by homocysteinylation

• Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
• October 2011

Cation exchange HPLC analysis of desmosines in elastin hydrolysates

• Analytical and Bioanalytical Chemistry
• September 2011

Analysis of site-specific N-homocysteinylation of human serum albumin in vitro and in v...

• Journal of Proteomics
• June 2011

Chemical Biology of Homocysteine Thiolactone and Related Metabolites

• January 2011

Elevated concentrations of Nɛ-homocysteinyl-lysine isopeptide in acute myocardial infar...

• Clinical Chemistry and Laboratory Medicine (CCLM)
• January 2011

Direct monitoring of albumin lysine-525 N-homocysteinylation in human serum by liquid c...

• Analytical Biochemistry
• October 2010

Identification and origin of Nε-homocysteinyl-lysine isopeptide in humans and mice

• Amino Acids
• May 2010

Reduced Homocysteine-Thiolactonase Activity in Alzheimer's Disease

• Journal of Alzheimer s Disease
• March 2010

An on-column derivatization method for the determination of homocysteine-thiolactone an...

• Amino Acids
• March 2010

On-column derivatization with o-phthaldialdehyde for fast determination of homocysteine...

• Analytical and Bioanalytical Chemistry
• February 2010

Properties of Escherichia coli EF-Tu mutants designed for fluorescence resonance energy...

• Protein Engineering Design and Selection
• January 2010

The Role of Paraoxonase 1 in the Detoxification of Homocysteine Thiolactone

• November 2009

Modulation of paraoxonase 1 and protein N-homocysteinylation by leptin and the syntheti...

• Journal of Endocrinology
• November 2009

Paraoxonase 1 protects against protein N-homocysteinylation in humans

• The FASEB Journal
• October 2009

Homocysteine editing and growth inhibition in Escherichia coli

• Microbiology
• April 2009

Genetic or nutritional disorders in homocysteine or folate metabolism increase protein ...

• The FASEB Journal
• February 2009

Role of homocysteine in aortic calcification and osteogenic cell differentiation

• Atherosclerosis
• February 2009

Immunohistochemical detection of N-homocysteinylated proteins in humans and mice

• Biomedicine & Pharmacotherapy
• September 2008

New method for the determination of protein N-linked homocysteine

• Analytical Biochemistry
• September 2008

Mutations in cystathionine  -synthase or methylenetetrahydrofolate reductase gene incre...

• The FASEB Journal
• August 2008

Plasma homocysteine is a determinant of tissue necrosis factor-α in hypertensive patients

• Biomedicine & Pharmacotherapy
• July 2008

Fluorescence enhancement on silver nanostructures: studies of components of ribosomal t...

• February 2008

Facile syntheses of [35S]homocysteine-thiolactone, [35S]homocystine, [35S]homocysteine,...

• Analytical Biochemistry
• November 2007

Differential Regulation of Homocysteine Transport in Vascular Endothelial and Smooth Mu...

• Arteriosclerosis Thrombosis and Vascular Biology
• September 2007

Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase defici...

• Molecular Genetics and Metabolism
• June 2007

Modification by Homocysteine Thiolactone Affects Redox Status of Cytochromec

• Biochemistry
• May 2007

Mutations in methylenetetrahydrofolate reductase or cystathionine  -syntase gene, or a ...

• The FASEB Journal
• February 2007

Mechanisms of homocysteine toxicity in humans

• Amino Acids
• February 2007

The molecular basis of homocysteine thiolactone-mediated vascular disease

• Clinical Chemistry and Laboratory Medicine (CCLM)
• January 2007

Mechanism of the Condensation of Homocysteine Thiolactone with Aldehydes

• Chemistry - A European Journal
• October 2006

Letter by Undas and Jakubowski Regarding Article, “Relationship Between Homocysteine an...

• Circulation
• October 2006

Protective Mechanisms against Homocysteine Toxicity

• Journal of Biological Chemistry
• June 2006

Plasma Homocysteine Affects Fibrin Clot Permeability and Resistance to Lysis in Human S...

• Arteriosclerosis Thrombosis and Vascular Biology
• June 2006

Synergistic, Random Sequential Binding of Substrates in Cobalamin-Independent Methionin...

• Biochemistry
• April 2006

Folic acid administration and antibodies against homocysteinylated proteins in subjects...

• Thrombosis and Haemostasis
• January 2006

The determination of homocysteine–thiolactone in human plasma

• Analytical Biochemistry
• February 2005

Urinary Excretion of Homocysteine-Thiolactone in Humans

• Clinical Chemistry
• February 2005

Anti-N-homocysteinylated protein autoantibodies and cardiovascular disease

• Clinical Chemistry and Laboratory Medicine (CCLM)
• January 2005

Antibodies to N-homocysteinylated albumin as a marker for earlyonset coronary artery di...

• Thrombosis and Haemostasis
• January 2005

The effects of age and hyperhomocysteinemia on the redox forms of plasma thiols

• Journal of Laboratory and Clinical Medicine
• November 2004

Purification of antibodies against N-homocysteinylated proteins by affinity chromatogra...

• Journal of Chromatography B
• August 2004

Autoantibodies Against N -Homocysteinylated Proteins in Humans

• Stroke
• June 2004

Molecular basis of homocysteine toxicity in humans

• Cellular and Molecular Life Sciences
• February 2004

Cross-talk between Cys34and Lysine Residues in Human Serum Albumin Revealed byN-Homocys...

• Journal of Biological Chemistry
• December 2003

On the health benefits of Allium sp.

• Nutrition
• February 2003

Homocysteine-Thiolactone and S-Nitroso-Homocysteine Mediate Incorporation of Homocystei...

• Clinical Chemistry and Laboratory Medicine (CCLM)
• January 2003

Metabolism of Homocysteine-thiolactone in Plants

• Journal of Biological Chemistry
• December 2002

Genomic Association/Linkage of Sodium Lithium Countertransport in CEPH Pedigrees

• Hypertension
• November 2002

The determination of homocysteine-thiolactone in biological samples

• Analytical Biochemistry
• September 2002

Homocysteine Is a Protein Amino Acid in Humans

• Journal of Biological Chemistry
• July 2002

Protein N-homocysteinylation: implications for atherosclerosis

• Biomedicine & Pharmacotherapy
• October 2001

Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural framewor...

• Journal of Molecular Biology
• August 2001

Genetic determinants of homocysteine thiolactonase activity in humans: implications for...

• FEBS Letters
• February 2001

Amino Acid Selectivity in the Aminoacylation of Coenzyme A and RNA Minihelices by Amino...

• Journal of Biological Chemistry
• September 2000

Translational Incorporation ofS-Nitrosohomocysteine into Protein

• Journal of Biological Chemistry
• May 2000

Calcium-dependent Human Serum Homocysteine Thiolactone Hydrolase

• Journal of Biological Chemistry
• February 2000

Misacylation of tRNALyswith Noncognate Amino Acids by Lysyl-tRNA Synthetase†

• Biochemistry
• June 1999

Aminoacylation of Coenzyme A and Pantetheine by Aminoacyl-tRNA Synthetases:  Possible L...

• Biochemistry
• April 1998

Aminoacyl Thioester Chemistry of Class II Aminoacyl-tRNA Synthetases†

• Biochemistry
• September 1997

Proofreading in trans by an aminoacyl-tRNA synthetase: a model for single site editing ...

• Nucleic Acids Research
• July 1996

The Synthetic/Editing Active Site of an Aminoacyl-tRNA Synthetase:  Evidence for Bindin...

• Biochemistry
• January 1996

Evidence that Uncharged tRNA Can Inhibit a Programmed Translational Frameshift inEscher...

• Journal of Molecular Biology
• August 1995

Proofreadingin Vivo

• Journal of Biological Chemistry
• July 1995

Synthesis of cysteine-containing dipeptides by aminpacyl-tRNAsynthetases

• Nucleic Acids Research
• January 1995

Role of carboxy-terminal region in proofreading function of methionyl-tRNA synthetase i...

• Biochemistry
• September 1994

Editing function ofEscherichia coli cysteinyl-tRNA synthetase: cyclization of cysteine ...

• Nucleic Acids Research
• January 1994

Synthesis of homocysteine thiolactone by methionyl-tRNA synthetase in cultured mammalia...

• FEBS Letters
• February 1993

Role of the metF and metJ genes on the vitamin B12 regulation of methionine gene expres...

• Biochemical and Biophysical Research Communications
• January 1992

Relationship between protein synthesis and concentrations of charged and uncharged tRNA...

• Proceedings of the National Academy of Sciences
• February 1990

Negative correlation between the abundance of Escherichia coli aminoacyl-tRNA families ...

• Journal of Theoretical Biology
• August 1988

Synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate (AppppA) from adenosine 5'-phosph...

• Biochemistry
• April 1988

Phosphonate analogs of diadenosine 5',5'''-P1,P4-tetraphosphate as substrates or inhibi...

• Biochemistry
• June 1987

Adenosylhomocysteinase from yellow lupine

• January 1987

Control of RNA and protein synthesis by the concentration of Trp-tRNATrp in Escherichia...

• Journal of Molecular Biology
• August 1983

Substrate specificity of S-Adenosylhomocysteinase

• Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
• January 1983

The mechanism of inhibition of valyl-tRNA synthetase by S-adenosylhomocysteine

• Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
• December 1982

S-Adenosylhomocysteinase from yellow lupine seeds: stoichiometry and reactions of the e...

• Biochemistry
• November 1981

Alternative pathways for editing non-cognate amino acids by aminoacyl-tRNA synthetases

• Nucleic Acids Research
• January 1981

Valyl-tRNA synthetase from yellow lupin seeds: hydrolysis of the enzyme-bound noncognat...

• Biochemistry
• October 1980

Polyamines and yellow lupin aminoacyl-tRNA synthetases

• FEBS Letters
• January 1980

A role for protein-protein interactions in the maintenance of active forms of aminoacyl...

• FEBS Letters
• July 1979

Yellow lupin (Lupinus luteus) aminoacyl-tRNA synthetases

• Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
• December 1978

Valyl-tRNA synthetase from yellow lupin seeds

• FEBS Letters
• November 1978

Adenosylhomocysteinase:Adenosine complex

• Biochemical and Biophysical Research Communications
• October 1978

The mechanism of the aminoacylation of transfer ribonucleic acid The kinetics and stoic...

• Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
• October 1978

Incomplete aminoacylation of tRNALeu catalyzed in vitro by leucyl-tRNA synthetase from ...

• Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
• April 1978

The determination of aminoacyl adenylate by thin-layer chromatography

• Analytical Biochemistry
• September 1977

Use of ω-aminohexyl-sepharose in the fractionation of escherichia coli B aminoacyl-tRNA...

• Journal of Chromatography A
• September 1977

Fractionation of plant aminoacyl-tRNA synthetases on tRNA-sepharose columns

• Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
• October 1975

The Plant Aminoacyl-tRNA Synthetases. Purification and Characterization of Valyl-tRNA, ...

• European Journal of Biochemistry
• March 1975

Transfer RNA methyltransferases from yellow lupin seeds: purification and properties

• Nucleic Acids Research
• January 1975

ω-Aminohexyl-Sepharose 4B, a new support for tRNA fractionation

• Journal of Chromatography A
• January 1975

Chromatography of plant aminoacyl-tRNA synthetases on ω-aminoalkyl sepharose columns

• FEBS Letters
• August 1973

Homocysteine Metabolism and Pathological Implications: The Homocysteine Thiolactone Hyp...