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  1. Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease
  2. The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1
  3. The Molecular Bases of Anti-oxidative and Anti-inflammatory Properties of Paraoxonase 1
  4. Homocysteine metabolites impair the PHF8/H4K20me1/mTOR/autophagy pathway by upregulating the expression of histone demethylase PHF8‐targeting microRNAs in human vascular endothelial cells and mice
  5. Association of GLOD4 with Alzheimer’s Disease in Humans and Mice
  6. Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease
  7. Association of GLOD4 with Alzheimer’s Disease in Humans and Mice
  8. Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease
  9. Association of Metallic and Nonmetallic Elements with Fibrin Clot Properties and Ischemic Stroke
  10. Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease
  11. Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1‐dependent epigenetic regulation of mTOR in cystathionine β‐synthase‐deficient mice
  12. Homocysteine Metabolites Impair the Phf8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of PHF8-targeting miR-22-3p and miR-1229-3p in Human Vascular Endothelial Cells
  13. Proteomic Exploration of Paraoxonase 1 Function in Health and Disease
  14. Homocysteine Metabolites Inhibit Autophagy and Elevate Amyloid Beta by Impairing Phf8/H4K20me1-dependent Epigenetic Regulation of mTOR in Cystathionine β-Synthase-Deficient Mice
  15. Depletion of bleomycin hydrolase (Blmh) downregulates histone demethylase Phf8, impairs mTOR signaling/autophagy, accelerates amyloid beta accumulation, and induces neurological deficits in mice
  16. Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice
  17. Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease
  18. Cystathionine β‐synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice
  19. Homocysteine thiolactone contributes to a prognostic value of fibrin clot structure/function in coronary artery disease patients
  20. Cystathionine β-synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice
  21. Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson’s Disease
  22. COVID-19 and One-Carbon Metabolism
  23. B Vitamins Prevent Iron-Associated Brain Atrophy and Domain-Specific Effects of Iron, Copper, Aluminum, and Silicon on Cognition in Mild Cognitive Impairment
  24. Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment
  25. Changes in redox plasma proteome of Pon1−/− mice are exacerbated by a hyperhomocysteinemic diet
  26. Proteome-Wide Analysis of Protein Lysine N-Homocysteinylation in Saccharomyces cerevisiae
  27. Anti‐ N ‐homocysteine‐protein autoantibodies are associated with impaired cognition
  28. Genetic Attenuation of Paraoxonase 1 Activity Induces Proatherogenic Changes in Plasma Proteomes of Mice and Humans
  29. Telomere Length and mtDNA Copy Number in Human Cystathionine β-synthase Deficiency
  30. Cystathionine β-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs−/− mice and thrombosis-prone CBS−/− humans
  31. Quantification of homocysteine thiolactone in human saliva and urine by gas chromatography-mass spectrometry
  32. Copper, heart disease and homocysteine thiolactone
  33. The Cbs Locus Affects the Expression of Senescence Markers and mtDNA Copy Number, but not Telomere Dynamics in Mice
  34. The Multispecies Probiotic Effectively Reduces Homocysteine Concentration in Obese Women: A Randomized Double-Blind Placebo-Controlled Study
  35. Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice
  36. Dysregulation of Epigenetic Mechanisms of Gene Expression in the Pathologies of Hyperhomocysteinemia
  37. Serum Proteome Alterations in Human Cystathionine β-Synthase Deficiency and Ischemic Stroke Subtypes
  38. Sex affects N-homocysteinylation at lysine residue 212 of albumin in mice
  39. Homocysteine Modification in Protein Structure/Function and Human Disease
  40. Protein N-Homocysteinylation and Colorectal Cancer
  41. Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice
  42. Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial
  43. Garlic extract favorably modifies markers of endothelial function in obese patients –randomized double blind placebo-controlled nutritional intervention
  44. Genetic variation in paraoxonase 1 and homocysteine thiolactone accumulation in humans
  45. Demethylation of methionine and keratin damage in human hair
  46. Homocysteine Editing, Thioester Chemistry, Coenzyme A, and the Origin of Coded Peptide Synthesis †
  47. Simultaneous Determination of Methionine and Homocysteine by on-column derivatization with o -phtaldialdehyde
  48. The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice
  49. Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs
  50. Quantification of urinary S- and N-homocysteinylated protein and homocysteine-thiolactone in mice
  51. Connective tissue damage by homocysteine
  52. Effects of endurance and endurance–strength exercise on biochemical parameters of liver function in women with abdominal obesity
  53. Aminoacyl-tRNA synthetases and the evolution of coded peptide synthesis: the Thioester World
  54. Quantification of homocysteine and cysteine by derivatization with pyridoxal 5'-phosphate and hydrophilic interaction liquid chromatography
  55. l -Arginine and vitamin C attenuate pro-atherogenic effects of high-fat diet on biomarkers of endothelial dysfunction in rats
  56. Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes in gene expression in human vascular endothelial cells
  57. Paraoxonase 1 deficiency and hyperhomocysteinemia alter the expression of mouse kidney proteins involved in renal disease
  58. The influence of selected antihypertensive drugs on zinc, copper, and iron status in spontaneously hypertensive rats
  59. Labeled EF-Tus for Rapid Kinetic Studies of Pretranslocation Complex Formation
  60. Inactivation of the Paraoxonase 1 Gene Affects the Expression of Mouse Brain Proteins Involved in Neurodegeneration
  61. Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease
  62. Hyperhomocysteinemia and Bleomycin Hydrolase Modulate the Expression of Mouse Brain Proteins Involved in Neurodegeneration
  63. Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis
  64. Identification of N-homocysteinylation sites in plasma proteins
  65. Effects of betaine on body composition, performance, and homocysteine thiolactone
  66. Correction
  67. The Mechanism and Consequences of Homocysteine Incorporation Into Protein in Humans
  68. Design and properties of efficient tRNA:EF-Tu FRET system for studies of ribosomal translation
  69. Homocysteine in Protein Structure/Function and Human Disease
  70. N-homocysteinylation of ovine prion protein induces amyloid-like transformation
  71. Paraoxonase 1 and homocysteine metabolism
  72. Metabolism and Neurotoxicity of Homocysteine Thiolactone in Mice: Evidence for a Protective Role of Paraoxonase 1
  73. Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase
  74. Plasma total homocysteine is a determinant of carotid intima-media thickness and circulating endothelial progenitor cells in patients with newly diagnosed hypertension
  75. Quality control in tRNA charging
  76. Aggregation and structural changes of αS1-, β- and κ-caseins induced by homocysteinylation
  77. Cation exchange HPLC analysis of desmosines in elastin hydrolysates
  78. Analysis of site-specific N-homocysteinylation of human serum albumin in vitro and in vivo using MALDI-ToF and LC-MS/MS mass spectrometry
  79. Chemical Biology of Homocysteine Thiolactone and Related Metabolites
  80. Elevated concentrations of Nɛ-homocysteinyl-lysine isopeptide in acute myocardial infarction: links with ADMA formation
  81. Direct monitoring of albumin lysine-525 N-homocysteinylation in human serum by liquid chromatography/mass spectrometry
  82. Identification and origin of Nε-homocysteinyl-lysine isopeptide in humans and mice
  83. Reduced Homocysteine-Thiolactonase Activity in Alzheimer's Disease
  84. An on-column derivatization method for the determination of homocysteine-thiolactone and protein N-linked homocysteine
  85. On-column derivatization with o-phthaldialdehyde for fast determination of homocysteine in human urine
  86. Properties of Escherichia coli EF-Tu mutants designed for fluorescence resonance energy transfer from tRNA molecules
  87. The Role of Paraoxonase 1 in the Detoxification of Homocysteine Thiolactone
  88. Modulation of paraoxonase 1 and protein N-homocysteinylation by leptin and the synthetic liver X receptor agonist T0901317 in the rat
  89. Paraoxonase 1 protects against protein N-homocysteinylation in humans
  90. Homocysteine editing and growth inhibition in Escherichia coli
  91. Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice
  92. Role of homocysteine in aortic calcification and osteogenic cell differentiation
  93. Immunohistochemical detection of N-homocysteinylated proteins in humans and mice
  94. New method for the determination of protein N-linked homocysteine
  95. Mutations in cystathionine  -synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans
  96. Plasma homocysteine is a determinant of tissue necrosis factor-α in hypertensive patients
  97. Fluorescence enhancement on silver nanostructures: studies of components of ribosomal translation in vitro
  98. Facile syntheses of [35S]homocysteine-thiolactone, [35S]homocystine, [35S]homocysteine, and [S-nitroso-35S]homocysteine
  99. Differential Regulation of Homocysteine Transport in Vascular Endothelial and Smooth Muscle Cells
  100. Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency
  101. Modification by Homocysteine Thiolactone Affects Redox Status of Cytochromec
  102. Mutations in methylenetetrahydrofolate reductase or cystathionine  -syntase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice
  103. Mechanisms of homocysteine toxicity in humans
  104. The molecular basis of homocysteine thiolactone-mediated vascular disease
  105. Mechanism of the Condensation of Homocysteine Thiolactone with Aldehydes
  106. Letter by Undas and Jakubowski Regarding Article, “Relationship Between Homocysteine and Mortality in Chronic Kidney Disease”
  107. Protective Mechanisms against Homocysteine Toxicity
  108. Plasma Homocysteine Affects Fibrin Clot Permeability and Resistance to Lysis in Human Subjects
  109. Synergistic, Random Sequential Binding of Substrates in Cobalamin-Independent Methionine Synthase†
  110. Folic acid administration and antibodies against homocysteinylated proteins in subjects with hyperhomocysteinemia
  111. The determination of homocysteine–thiolactone in human plasma
  112. Urinary Excretion of Homocysteine-Thiolactone in Humans
  113. Anti-N-homocysteinylated protein autoantibodies and cardiovascular disease
  114. Antibodies to N-homocysteinylated albumin as a marker for earlyonset coronary artery disease in men
  115. The effects of age and hyperhomocysteinemia on the redox forms of plasma thiols
  116. Purification of antibodies against N-homocysteinylated proteins by affinity chromatography on Nω-homocysteinyl-aminohexyl-Agarose
  117. Autoantibodies Against N -Homocysteinylated Proteins in Humans
  118. Molecular basis of homocysteine toxicity in humans
  119. Cross-talk between Cys34and Lysine Residues in Human Serum Albumin Revealed byN-Homocysteinylation
  120. On the health benefits of Allium sp.
  121. Homocysteine-Thiolactone and S-Nitroso-Homocysteine Mediate Incorporation of Homocysteine into Protein in Humans
  122. Metabolism of Homocysteine-thiolactone in Plants
  123. Genomic Association/Linkage of Sodium Lithium Countertransport in CEPH Pedigrees
  124. The determination of homocysteine-thiolactone in biological samples
  125. Homocysteine Is a Protein Amino Acid in Humans
  126. Protein N-homocysteinylation: implications for atherosclerosis
  127. Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions
  128. Genetic determinants of homocysteine thiolactonase activity in humans: implications for atherosclerosis
  129. Amino Acid Selectivity in the Aminoacylation of Coenzyme A and RNA Minihelices by Aminoacyl-tRNA Synthetases
  130. Homocysteine Thiolactone and Protein Homocysteinylation in Human Endothelial Cells
  131. Translational Incorporation ofS-Nitrosohomocysteine into Protein
  132. Calcium-dependent Human Serum Homocysteine Thiolactone Hydrolase
  133. Misacylation of tRNALyswith Noncognate Amino Acids by Lysyl-tRNA Synthetase†
  134. Aminoacylation of Coenzyme A and Pantetheine by Aminoacyl-tRNA Synthetases:  Possible Link between Noncoded and Coded Peptide Synthesis†
  135. Aminoacyl Thioester Chemistry of Class II Aminoacyl-tRNA Synthetases†
  136. Proofreading in trans by an aminoacyl-tRNA synthetase: a model for single site editing by isoleucyl-tRNA synthetase
  137. The Synthetic/Editing Active Site of an Aminoacyl-tRNA Synthetase:  Evidence for Binding of Thiols in the Editing Subsite†
  138. Evidence that Uncharged tRNA Can Inhibit a Programmed Translational Frameshift inEscherichia coli
  139. Proofreadingin Vivo
  140. Synthesis of cysteine-containing dipeptides by aminpacyl-tRNAsynthetases
  141. Role of carboxy-terminal region in proofreading function of methionyl-tRNA synthetase in Escherichia coli
  142. Editing function ofEscherichia coli cysteinyl-tRNA synthetase: cyclization of cysteine to cysteine thiolactone
  143. Synthesis of homocysteine thiolactone by methionyl-tRNA synthetase in cultured mammalian cells
  144. Role of the metF and metJ genes on the vitamin B12 regulation of methionine gene expression: Involvement of N5-methyltetrahydrofolic acid
  145. Relationship between protein synthesis and concentrations of charged and uncharged tRNATrp in Escherichia coli.
  146. Negative correlation between the abundance of Escherichia coli aminoacyl-tRNA families and their affinities for elongation factor Tu-GTP
  147. Synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate (AppppA) from adenosine 5'-phosphosulfate and adenosine 5'-triphosphate catalyzed by yeast AppppA phosphorylase
  148. Phosphonate analogs of diadenosine 5',5'''-P1,P4-tetraphosphate as substrates or inhibitors of prokaryotic and eukaryotic enzymes degrading dinucloside tetraphosphates
  149. Adenosylhomocysteinase from yellow lupine
  150. Control of RNA and protein synthesis by the concentration of Trp-tRNATrp in Escherichia coli infected with bacteriophage MS2
  151. Substrate specificity of S-Adenosylhomocysteinase
  152. The mechanism of inhibition of valyl-tRNA synthetase by S-adenosylhomocysteine
  153. S-Adenosylhomocysteinase from yellow lupine seeds: stoichiometry and reactions of the enzyme.cntdot.adenosine complex
  154. Alternative pathways for editing non-cognate amino acids by aminoacyl-tRNA synthetases
  155. Valyl-tRNA synthetase from yellow lupin seeds: hydrolysis of the enzyme-bound noncognate aminoacyl adenylate as a possible mechanism of increasing specificity of the aminoacyl-tRNA synthetase
  156. Polyamines and yellow lupin aminoacyl-tRNA synthetases
  157. A role for protein-protein interactions in the maintenance of active forms of aminoacyl-tRNA synthetases
  158. Yellow lupin (Lupinus luteus) aminoacyl-tRNA synthetases
  159. Valyl-tRNA synthetase from yellow lupin seeds
  160. Adenosylhomocysteinase:Adenosine complex
  161. The mechanism of the aminoacylation of transfer ribonucleic acid The kinetics and stoichiometry of the lysis of aminoacyl-tRNA
  162. Incomplete aminoacylation of tRNALeu catalyzed in vitro by leucyl-tRNA synthetase from Escherichia coli B
  163. The determination of aminoacyl adenylate by thin-layer chromatography
  164. Use of ω-aminohexyl-sepharose in the fractionation of escherichia coli B aminoacyl-tRNA synthetases
  165. Fractionation of plant aminoacyl-tRNA synthetases on tRNA-sepharose columns
  166. The Plant Aminoacyl-tRNA Synthetases. Purification and Characterization of Valyl-tRNA, Tryptophanyl-tRNA and Seryl-tRNA Synthetases from Yellow-Lupin Seeds
  167. Transfer RNA methyltransferases from yellow lupin seeds: purification and properties
  168. ω-Aminohexyl-Sepharose 4B, a new support for tRNA fractionation
  169. Chromatography of plant aminoacyl-tRNA synthetases on ω-aminoalkyl sepharose columns
  170. Homocysteine Metabolism and Pathological Implications: The Homocysteine Thiolactone Hypothesis of Vascular Disease