All Stories

  1. Retroviral adapters hijack the RNA helicase UPF1 in a CRM1/XPO1-dependent manner and reveal proviral roles of UPF1

    Article • Nucleic Acids Research, May 2025, Oxford University Press (OUP)

    Helene Dutartre

  2. Lyon, at the center of the global virology research challenge

    Article • Virologie, April 2025, John Libbey Eurotext

    Helene Dutartre

  3. Peculiar transcriptional reprogramming with functional impairment of dendritic cells upon exposure to transformed HTLV-1-infected cells

    Article • PLoS Pathogens, September 2024, PLOS

    Helene Dutartre

  4. Peculiar transcriptional reprogramming with functional impairment of dendritic cells upon exposure to transformed HTLV-1-infected cells

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Helene Dutartre

  5. Isolation of Viral Biofilms From HTLV-1 Chronically Infected T Cells and Integrity Analysis

    Article • BIO-PROTOCOL, January 2024, Bio-Protocol, LLC

    Helene Dutartre

  6. HTLV-1 biofilm polarization maintained by tetraspanin CD82 is required for efficient viral transmission

    Article • mBio, December 2023, ASM Journals

    Helene Dutartre

  7. Tetraspanin CD82 maintains HTLV-1 biofilm polarization and is required for efficient viral transmission

    Article • May 2023, Cold Spring Harbor Laboratory Press

    Helene Dutartre

  8. STLV-1 Commonly Targets Neurons in the Brain of Asymptomatic Non-Human Primates

    Article • mBio, April 2023, ASM Journals

    Helene Dutartre

  9. Viral-induced neuroinflammation: Different mechanisms converging to similar exacerbated glial responses

    Article • Frontiers in Neuroscience, March 2023, Frontiers

    Helene Dutartre

  10. Un monde de virus

    Article • médecine/sciences, December 2022, EDP Sciences

    Helene Dutartre

  11. Is the HTLV-1 Retrovirus Targeted by Host Restriction Factors?

    Article • Viruses, July 2022, MDPI AG

    Helene Dutartre

  12. Immunoprofiling of fresh HAM/TSP blood samples shows altered innate cell responsiveness

    Article • PLoS Neglected Tropical Diseases, November 2021, PLOS

    Helene Dutartre

  13. Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread

    Article • Retrovirology, February 2021, Springer Science + Business Media

    Helene Dutartre

  14. Renaud Mahieux (1968-2020)

    Article • Virologie, December 2020, John Libbey Eurotext

    Helene Dutartre

  15. Microbial Biofilms: Human T-cell Leukemia Virus Type 1 First in Line for Viral Biofilm but Far Behind Bacterial Biofilms

    Article • Frontiers in Microbiology, September 2020, Frontiers

    Helene Dutartre

  16. Letter to the Editor

    Article • Journal of Virological Methods, February 2020, Elsevier

    Helene Dutartre

  17. HTLV-1 infection of myeloid cells: from transmission to immune alterations

    Article • Retrovirology, December 2019, Springer Science + Business Media

    Helene Dutartre

  18. STLV-1 as a model for studying HTLV-1 infection

    Article • Retrovirology, December 2019, Springer Science + Business Media

    Helene Dutartre

  19. SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function

    Article • Scientific Reports, November 2019, Springer Science + Business Media

    Helene Dutartre

  20. HTLV-1 Extracellular Vesicles Promote Cell-to-Cell Contact

    Article • Frontiers in Microbiology, September 2019, Frontiers

    Helene Dutartre

  21. Sensing of cell-associated HTLV by plasmacytoid dendritic cells is regulated by dense β-galactoside glycosylation

    Article • PLoS Pathogens, February 2019, PLOS

    Dr Marlene DREUX, Helene Dutartre

  22. Cytokine Networks Dysregulation during HTLV-1 Infection and Associated Diseases

    Article • Viruses, December 2018, MDPI AG

    Helene Dutartre

  23. How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy

    Article • Frontiers in Microbiology, March 2018, Frontiers

    Helene Dutartre

  24. HTLV-1 et cellules dendritiques

    Article • médecine/sciences, February 2018, EDP Sciences

    Helene Dutartre

  25. HTLV-1, the Other Pathogenic Yet Neglected Human Retrovirus: From Transmission to Therapeutic Treatment

    Article • Viruses, December 2017, MDPI AG

    Helene Dutartre

  26. How does susceptibility to HTLV-1 infection varies with the maturation state of dendritic cells?

    Article • Future Virology, October 2017, Future Medicine

    Helene Dutartre, Gerges Rizkallah

  27. Quand le cytosquelette d’actine fait le jeu des rétrovirus

    Article • médecine/sciences, October 2017, EDP Sciences

    Helene Dutartre, Gerges Rizkallah

  28. Correction: Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells

    Article • PLoS Pathogens, July 2017, PLOS

    Gerges Rizkallah, Helene Dutartre

  29. Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells

    Article • PLoS Pathogens, April 2017, PLOS

    Helene Dutartre

  30. Quantitative Analysis of Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection Using Co-Culture with Jurkat LTR-Luciferase or Jurkat LTR-GFP Reporter Cells

    Article • January 2017, Springer Science + Business Media

    Helene Dutartre

  31. Les cellules dendritiques folliculaires des ganglions stockent du VIH-1 infectieux malgré les traitements antirétroviraux

    Article • médecine/sciences, October 2016, EDP Sciences

    Helene Dutartre

  32. Cell-Free versus Cell-to-Cell Infection by Human Immunodeficiency Virus Type 1 and Human T-Lymphotropic Virus Type 1: Exploring the Link among Viral Source, Viral Trafficking, and Viral Replication

    Article • Journal of Virology, June 2016, ASM Journals

    Helene Dutartre

  33. Viral Source-Independent High Susceptibility of Dendritic Cells to Human T-Cell Leukemia Virus Type 1 Infection Compared to That of T Lymphocytes

    Article • Journal of Virology, August 2015, ASM Journals

    Helene Dutartre

  34. Transmission intercellulaire de HTLV-1

    Article • médecine/sciences, June 2015, EDP Sciences

    Gerges Rizkallah, Helene Dutartre

  35. ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity

    Article • Retrovirology, November 2014, Springer Science + Business Media

    Helene Dutartre

  36. Alpha Interferon Restricts Human T-Lymphotropic Virus Type 1 and 2 De Novo Infection through PKR Activation

    Article • Journal of Virology, October 2013, ASM Journals

    Professor renaud mahieux, Helene Dutartre

  37. Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

    Article • Immunity, April 2013, Elsevier

    Helene Dutartre

  38. Brucella β 1,2 Cyclic Glucan Is an Activator of Human and Mouse Dendritic Cells

    Article • PLoS Pathogens, November 2012, PLOS

    Professor Ignacio Moriyon, Helene Dutartre

  39. Phosphoramidate Dinucleosides as Inhibitors of Hepatitis C Virus Subgenomic Replicon and NS5B Polymerase Activity

    Article • Antiviral Research, May 2011, Elsevier

    Johan Neyts, Helene Dutartre

  40. 3′-Deoxy Phosphoramidate Dinucleosides as Improved Inhibitors of Hepatitis C Virus Subgenomic Replicon and NS5B Polymerase Activity

    Article • Journal of Medicinal Chemistry, September 2010, American Chemical Society (ACS)

    Johan Neyts, Helene Dutartre

  41. Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step

    Article • Antiviral Research, October 2009, Elsevier

    Johan Neyts, Helene Dutartre

  42. A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase

    Article • Antiviral Research, June 2009, Elsevier

    Johan Neyts, Helene Dutartre

  43. The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

    Article • Journal of Virology, April 2009, ASM Journals

    Helene Dutartre

  44. Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors

    Article • Journal of Medicinal Chemistry, September 2008, American Chemical Society (ACS)

    Johan Neyts, Helene Dutartre

  45. Comparative Virtual and Experimental Medium Throughput Screening for Hepatitis C Virus Polymerase Inhibitors

    Article • Antiviral Research, May 2008, Elsevier

    Helene Dutartre

  46. The Imidazopyrrolopyridine Analogue AG110 Is a Novel, Highly Selective Inhibitor of Pestiviruses That Targets the Viral RNA-Dependent RNA Polymerase at a Hot Spot for Inhibition of Viral Replication

    Article • Journal of Virology, August 2007, ASM Journals

    Johan Neyts, Helene Dutartre

  47. Substituted Imidazopyridines as Potent Inhibitors of Hepatitis C Virus Replication that Target the Viral Polymerase

    Article • Antiviral Research, June 2007, Elsevier

    Johan Neyts, Helene Dutartre

  48. The Imidazopyrrolopyridine Analogue AG110 is a Novel, Highly Selective Inhibitor of Pestivirus Replication and Targets the viral RNA-dependent RNA Polymerase

    Article • Antiviral Research, June 2007, Elsevier

    Johan Neyts, Helene Dutartre

  49. General Catalytic Deficiency of Hepatitis C Virus RNA Polymerase with an S282T Mutation and Mutually Exclusive Resistance towards 2′-Modified Nucleotide Analogues

    Article • Antimicrobial Agents and Chemotherapy, September 2006, ASM Journals

    Helene Dutartre

  50. Structural and Functional Basis for ADP-Ribose and Poly(ADP-Ribose) Binding by Viral Macro Domains

    Article • Journal of Virology, September 2006, ASM Journals

    Helene Dutartre

  51. Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases

    Article • Virology, July 2006, Elsevier

    Professor philippe Desprès, Helene Dutartre

  52. Synthesis and Anti-BVDV Activity of Acridones As New Potential Antiviral Agents1

    Article • Journal of Medicinal Chemistry, April 2006, American Chemical Society (ACS)

    Johan Neyts, Helene Dutartre

  53. A Novel, Highly Selective Inhibitor of Pestivirus Replication That Targets the Viral RNA-Dependent RNA Polymerase

    Article • Journal of Virology, January 2006, ASM Journals

    Johan Neyts, Helene Dutartre

  54. The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymerases

    Article • BMC Bioinformatics, October 2005, Springer Science + Business Media

    Helene Dutartre

  55. A Relaxed Discrimination of 2′-O-Methyl-GTP Relative to GTP between de Novo and Elongative RNA Synthesis by the Hepatitis C RNA-dependent RNA Polymerase NS5B

    Article • Journal of Biological Chemistry, February 2005, Elsevier

    Helene Dutartre

  56. The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world

    Article • Proceedings of the National Academy of Sciences, March 2004, Proceedings of the National Academy of Sciences

    Professor Eric J. Snijder, Helene Dutartre

  57. Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets

    Article • Molecular Pharmacology, March 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Helene Dutartre

  58. Dimer stabilization upon activation of the transcriptional antiterminator LicT 1 1Edited by T. Richmond

    Article • Journal of Molecular Biology, December 2001, Elsevier

    Helene Dutartre

  59. Sites of positive and negative regulation in the Bacillus subtilis antiterminators LicT and SacY

    Article • Molecular Microbiology, September 2001, Wiley

    Dr Dominique G Le Coq, Helene Dutartre

  60. Parameters involved in the recognition of fresh human leukemic blasts by tumor-specific cytolytic T cell clones: a model study

    Article • Leukemia Research, October 2000, Elsevier

    Helene Dutartre

  61. Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 1 Nef Proteins Show Distinct Patterns and Mechanisms of Src Kinase Activation

    Article • Journal of Virology, July 1999, ASM Journals

    Helene Dutartre

  62. Human Immunodeficiency Virus Type 1 Nef Protein Sensitizes CD4+ T Lymphoid Cells to Apoptosis via Functional Upregulation of the CD95/CD95 Ligand Pathway

    Article • Blood, February 1999, American Society of Hematology

    Helene Dutartre

  63. The Human Immunodeficiency Virus Type 1 NEF Protein Binds the Src-Related Tyrosine Kinase Lck SH2 Domain Through a Novel Phosphotyrosine Independent Mechanism

    Article • Virology, August 1998, Elsevier

    Helene Dutartre

  64. The role of HIV1 Nef in T-cell activation: Nef impairs induction of Th1 cytokines and interacts with the Src family tyrosine kinase Lck

    Article • Research in Virology, January 1997, Elsevier

    Helene Dutartre

  65. Similarity between Nef of primate lentiviruses and p15E of murine and feline leukaemia viruses

    Article • AIDS, April 1996, Wolters Kluwer Health

    Helene Dutartre

  66. Physical and Functional Interaction of Nef with Lck

    Article • Journal of Biological Chemistry, March 1996, Elsevier

    Helene Dutartre

  67. Characterization of a Monoclonal Antibody Specific for the Ras-Related GTP-Binding Protein Rho A

    Article • Biochemical and Biophysical Research Communications, November 1993, Elsevier

    Helene Dutartre