PhD. Guillermo Lopez-Lluch

Age-related mitochondrial dysfunction as a key factor in COVID-19 disease

• Experimental Gerontology
• December 2020

Physiopathology of Lifestyle Interventions in Non-Alcoholic Fatty Liver Disease (NAFLD)

• Nutrients
• November 2020

Involvement of the mitochondrial nuclease EndoG in the regulation of cell proliferation...

• Redox Biology
• October 2020

High coenzyme Q10 plasma levels improve stress and damage markers in professional ...

• International Journal for Vitamin and Nutrition Research
• July 2020

Resveratrol Regulates the Expression of Genes Involved in CoQ Synthesis in Liver in Mic...

• Antioxidants
• May 2020

The Important Role of CoQ10 in Aging

• Antioxidants
• November 2019

ADCK2 Haploinsufficiency Reduces Mitochondrial Lipid Oxidation and Causes Myopathy Asso...

• Journal of Clinical Medicine
• September 2019

Calorie Restriction

• January 2019

PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-li...

• Proceedings of the National Academy of Sciences
• December 2018

Mitochondrial dysfunction in metabolism and ageing: shared mechanisms and outcomes?

• Biogerontology
• August 2018

The Impact of Aging, Calorie Restriction and Dietary Fat on Autophagy Markers and Mitoc...

• The Journals of Gerontology Series A
• July 2018

High-Intensity Interval Training Combined With Vibration and Dietary Restriction Improv...

• Dose-Response
• July 2018

Bioavailability of coenzyme Q 10 supplements depends on carrier lipids and solubilization

• Nutrition
• June 2018

SOX2 expression diminishes with ageing in several tissues in mice and humans

• Mechanisms of Ageing and Development
• March 2018

Coenzyme Q10 Supplementation in Aging and Disease

• Frontiers in Physiology
• February 2018

La expresión del complejo de síntesis de coenzima Q es regulada durante el envejecimiento

• Revista Española de Geriatría y Gerontología
• November 2017

Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity

• Mechanisms of Ageing and Development
• March 2017

Resveratrol primes the effects of physical activity in old mice

• British Journal Of Nutrition
• August 2016

mitochondria in muscle physiology

• Acta Physiologica
• July 2016

Omega-3 fatty acids partially revert the metabolic gene expression profile induced by l...

• Experimental Gerontology
• May 2016

Vacuolar H+-Pyrophosphatase AVP1 is Involved in Amine Fungicide Tolerance in Arabidopsi...

• Frontiers in Plant Science
• February 2016

Agin, calorie restriction and kidney

• Aging Cell
• February 2016

Calorie restriction as an intervention in ageing

• The Journal of Physiology
• January 2016

Análisis de la edad morfológica en nadadores y triatletas adolescentes

• Nutrición Hospitalaria
• January 2016

RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-tran...

• RNA Biology
• December 2015

Facing challenges in an ageing world

• Biogerontology
• August 2015

Mitochondrial responsibility in ageing process: innocent, suspect or guilty

• Biogerontology
• June 2015

Organ and tissue-dependent effect of resveratrol and exercise on antioxidant defenses o...

• Aging Clinical and Experimental Research
• May 2015

The influence of dietary fat source on liver and skeletal muscle mitochondrial modifica...

• Biogerontology
• April 2015

Anti-inflammatory effect of resveratrol in old mice liver

• Experimental Gerontology
• April 2015

Membrane-Bound CYB5R3 Is a Common Effector of Nutritional and Oxidative Stress Response...

• Antioxidants & Redox Signaling
• October 2014

The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice

• The Journals of Gerontology Series A
• October 2014

Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie ...

• Experimental Gerontology
• August 2014

Relationship between functional capacity and body mass index with plasma coenzyme Q10 a...

• Experimental Gerontology
• April 2014

Dietary Fat and Aging Modulate Apoptotic Signaling in Liver of Calorie-Restricted Mice

• The Journals of Gerontology Series A
• April 2014

Age-Dependent Effect of Every-Other-Day Feeding and Aerobic Exercise in Ubiquinone Leve...

• The Journals of Gerontology Series A
• February 2014

Physical activity affects plasma coenzyme Q10 levels differently in young and old humans

• Biogerontology
• January 2014

Modulation of Endogenous Antioxidant Activity by Resveratrol and Exercise in Mouse Live...

• The Journals of Gerontology Series A
• July 2013

Influencia de la capacidad funcional sobre el perfil lipídico, daño muscular y perfil b...

• Revista Andaluza de Medicina del Deporte
• June 2013

Inorganic Pyrophosphatase Defects Lead to Cell Cycle Arrest and Autophagic Cell Death t...

• Journal of Biological Chemistry
• March 2013

Alterations of Ultrastructural and Fission/Fusion Markers in Hepatocyte Mitochondria Fr...

• The Journals of Gerontology Series A
• February 2013

The influence of dietary lipid composition on liver mitochondria from mice following 1 ...

• Bioscience Reports
• December 2012

Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal ...

• AGE
• November 2012

The Influence of Dietary Lipid Composition on Skeletal Muscle Mitochondria From Mice Fo...

• The Journals of Gerontology Series A
• April 2012

Resveratrol in Cancer: Cellular and Mitochondrial Consequences of Proton Transport Inhi...

• Current Pharmaceutical Design
• April 2012

Sirtuin-Dependent Metabolic Control and Its Role in the Aging Process

• March 2012

Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues

• Free Radical Biology and Medicine
• June 2011

Caloric restriction reduces IgA levels and modifies cytokine mRNA expression in mouse s...

• The Journal of Nutritional Biochemistry
• June 2011

Muscle Physiology Changes Induced by Every Other Day Feeding and Endurance Exercise in ...

• PLoS ONE
• November 2010

Complex I-Associated Hydrogen Peroxide Production Is Decreased and Electron Transport C...

• PLoS ONE
• September 2010

Is coenzyme Q a key factor in aging?

• Mechanisms of Ageing and Development
• April 2010

N-acetylcysteine, coenzyme Q10 and superoxide dismutase mimetic prevent mitochondrial c...

• Chemico-Biological Interactions
• September 2009

NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast

• Aging Cell
• April 2009

HDAC and Hsp90 inhibitors down-regulatePTTG1/securin but do not induce aneuploidy

• Genes Chromosomes and Cancer
• February 2009

Protein Kinase C as an Effector of Lipid-Derived Second Messengers

• September 2008

Enhanced induction of apoptosis in a radio-resistant bladder tumor cell line by combine...

• Radiation and Environmental Biophysics
• September 2008

Mitochondrial biogenesis and healthy aging

• Experimental Gerontology
• September 2008

Molecular Bases of Caloric Restriction Regulation of Neuronal Synaptic Plasticity

• Molecular Neurobiology
• August 2008

Dicoumarol down-regulates human PTTG1/Securin mRNA expression through inhibition of Hsp90

• Molecular Cancer Therapeutics
• March 2008

Caloric Restriction Increases Learning Consolidation and Facilitates Synaptic Plasticit...

• Journal of Neuroscience
• September 2007

Resveratrol improves health and survival of mice on a high-calorie diet

• Nature
• November 2006

Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

• Proceedings of the National Academy of Sciences
• January 2006

Coenzyme Q distribution in HL-60 human cells depends on the endomembrane system

• Biochimica et Biophysica Acta (BBA) - Biomembranes
• July 2005

Mouse liver plasma membrane redox system activity is altered by aging and modulated by ...

• AGE
• June 2005

Dicoumarol relieves serum withdrawal-induced G0/1 blockade in HL-60 cells through a sup...

• Biochemical Pharmacology
• June 2005

Inhibition of COX activity by NSAIDs or ascorbate increases cAMP levels and enhances di...

• Archives of Biochemistry and Biophysics
• April 2005

Coenzyme Q and the regulation of intracellular steady-state levels of superoxide in HL-...

• BioFactors
• January 2005

Specificity of coenzyme Q10 for a balanced function of respiratory chain and endogenous...

• Biochimica et Biophysica Acta (BBA) - Bioenergetics
• January 2005

Demethoxy-Q, An Intermediate of Coenzyme Q Biosynthesis, Fails to Support Respiration i...

• Journal of Biological Chemistry
• April 2004

Calorie restriction attenuates age-related alterations in the plasma membrane antioxida...

• Experimental Gerontology
• March 2004

Effects of microinjected small GTPases on the actin cytoskeleton of human neutrophils

• Journal of Anatomy
• October 2003

Antioxidant response induced by serum withdrawal protects HL-60 cells against inhibitio...

• BioFactors
• January 2003

• Journal of Bioenergetics and Biomembranes
• January 2003

Involvement of protein kinase D in Fcγ-receptor activation of the NADPH oxidase in neut...

• Biochemical Journal
• April 2002

Involvement of protein kinase D in Fcγ-receptor activation of the NADPH oxidase in neut...

• Biochemical Journal
• April 2002

Ceramide-dependent Caspase 3 Activation is Prevented by Coenzyme Q from Plasma Membrane...

• Free Radical Research
• January 2002

Protein kinase C-δ C2-like domain is a binding site for actin and enables actin redistr...

• Biochemical Journal
• July 2001

Protein kinase C-δ C2-like domain is a binding site for actin and enables actin redistr...

• Biochemical Journal
• July 2001

Cellular redox state and activating protein-1 are involved in ascorbate effect on calci...

• PROTOPLASMA
• March 2001

Extramitochondrial Functions of Coenzyme Q

• August 2000

Coenzyme Q Protects Cells Against Serum Withdrawal-Induced Apoptosis by Inhibition of C...

• Antioxidants & Redox Signaling
• June 2000

Plasma membrane redox system protects cells against oxidative stress

• Redox Report
• April 2000

Redox regulation of cAMP levels by ascorbate in 1,25-dihydroxy- vitamin D3-induced diff...

• Biochemical Journal
• April 1998

Ascorbate and α-Tocopherol Prevent Apoptosis Induced by Serum Removal Independent of Bcl-2

• Archives of Biochemistry and Biophysics
• July 1997

• Journal of Bioenergetics and Biomembranes
• January 1997

Ascorbate Increases the 1,25 Dihydroxyvitamin D 3 -Induced Monocytic Differentiation of...

• Calcified Tissue International
• October 1996

Plasma membrane redox system during HL-60 induced differentiation

• PROTOPLASMA
• March 1995