All Stories

  1. An antibody against ACBP/DBI protects the heart, liver and lung against multiple types of injury
  2. Cystic Fibrosis: New Insights into Therapeutic Approaches
  3. The elusive “hunger protein”: an appetite-stimulatory factor that is overabundant in human obesity
  4. Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies
  5. A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice
  6. Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion
  7. Cell-autonomous, paracrine and neuroendocrine feedback regulation of autophagy by DBI/ACBP (diazepam binding inhibitor, acyl-CoA binding protein): the obesity factor
  8. Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity
  9. Contribution of annexin A1 to anticancer immunosurveillance
  10. Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade
  11. Trial watch: dendritic cell vaccination for cancer immunotherapy
  12. 4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects
  13. Caloric restriction promotes the stemness and antitumor activity of T lymphocytes
  14. Autophagy represses hepatic carcinogenesis
  15. A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers
  16. Tumor lysis with LTX-401 creates anticancer immunity
  17. Crizotinib – a tyrosine kinase inhibitor that stimulates immunogenic cell death
  18. Trial watch: dietary interventions for cancer therapy
  19. Metabolic enzymes expressed by cancer cells impact the immune infiltrate
  20. Failure of immunosurveillance accelerates aging
  21. Etiological involvement of CFTR in apparently unrelated human diseases
  22. Anticancer effects of anti-CD47 immunotherapy in vivo
  23. Spermidine reduces cancer-related mortality in humans
  24. The intimate relationship between gut microbiota and cancer immunotherapy
  25. Potent immunosuppressive effects of the oncometabolite R-2-hydroxyglutarate
  26. Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells
  27. Trial Watch: Toll-like receptor agonists in cancer immunotherapy
  28. Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
  29. Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions
  30. Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?
  31. Systemic autophagy in the therapeutic response to anthracycline-based chemotherapy
  32. Trial watch: peptide-based vaccines in anticancer therapy
  33. Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
  34. TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves
  35. Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts
  36. Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
  37. Repurposing therapies for the personalised treatment of cystic fibrosis
  38. Immune effectors responsible for the elimination of hyperploid cancer cells
  39. The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1
  40. Heating it up: Oncolytic viruses make tumors ‘hot’ and suitable for checkpoint blockade immunotherapies
  41. Mitochondrial permeability transition involves dissociation of F 1 F O ATP synthase dimers and C‐ring conformation
  42. Trial watch: Dendritic cell-based anticancer immunotherapy
  43. Se manger soi-même, avec modération, une condition pour garder un esprit sain dans un corps sain
  44. The oncolytic peptide LTX-315 triggers necrotic cell death