All Stories

  1. Neutralization of acyl-CoA-binding protein attenuates glucocorticoid-mediated suppression of cancer immunosurveillance
  2. Acyl-CoA-binding protein as a driver of pathological aging
  3. An antibody against ACBP/DBI protects the heart, liver and lung against multiple types of injury
  4. Cystic Fibrosis: New Insights into Therapeutic Approaches
  5. The elusive “hunger protein”: an appetite-stimulatory factor that is overabundant in human obesity
  6. Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies
  7. A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice
  8. Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion
  9. Cell-autonomous, paracrine and neuroendocrine feedback regulation of autophagy by DBI/ACBP (diazepam binding inhibitor, acyl-CoA binding protein): the obesity factor
  10. Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity
  11. Contribution of annexin A1 to anticancer immunosurveillance
  12. Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade
  13. Trial watch: dendritic cell vaccination for cancer immunotherapy
  14. 4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects
  15. Caloric restriction promotes the stemness and antitumor activity of T lymphocytes
  16. Autophagy represses hepatic carcinogenesis
  17. A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers
  18. Tumor lysis with LTX-401 creates anticancer immunity
  19. Crizotinib – a tyrosine kinase inhibitor that stimulates immunogenic cell death
  20. Trial watch: dietary interventions for cancer therapy
  21. Metabolic enzymes expressed by cancer cells impact the immune infiltrate
  22. Failure of immunosurveillance accelerates aging
  23. Etiological involvement of CFTR in apparently unrelated human diseases
  24. Anticancer effects of anti-CD47 immunotherapy in vivo
  25. Spermidine reduces cancer-related mortality in humans
  26. The intimate relationship between gut microbiota and cancer immunotherapy
  27. Potent immunosuppressive effects of the oncometabolite R-2-hydroxyglutarate
  28. Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells
  29. Trial Watch: Toll-like receptor agonists in cancer immunotherapy
  30. Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
  31. Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions
  32. Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?
  33. Systemic autophagy in the therapeutic response to anthracycline-based chemotherapy
  34. Trial watch: peptide-based vaccines in anticancer therapy
  35. Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
  36. TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves
  37. Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts
  38. Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
  39. Repurposing therapies for the personalised treatment of cystic fibrosis
  40. Immune effectors responsible for the elimination of hyperploid cancer cells
  41. The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1
  42. Heating it up: Oncolytic viruses make tumors ‘hot’ and suitable for checkpoint blockade immunotherapies
  43. Mitochondrial permeability transition involves dissociation of F 1 F O ATP synthase dimers and C‐ring conformation
  44. Trial watch: Dendritic cell-based anticancer immunotherapy
  45. Se manger soi-même, avec modération, une condition pour garder un esprit sain dans un corps sain
  46. The oncolytic peptide LTX-315 triggers necrotic cell death