All Stories

  1. Diketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465A
  2. Richness of cultivable endophytic fungi along an altitudinal gradient in wet forests of Costa Rica
  3. Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
  4. Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts
  5. Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis
  6. Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts
  7. The Combined Use of Alphavirus Replicons and Pseudoinfectious Particles for the Discovery of Antivirals Derived from Natural Products
  8. Naphthalenones and Isocoumarins from a Costa Rican Fungus Xylariaceae sp. CR1546C
  9. Uncovering the Cultivable Microbial Diversity of Costa Rican Beetles and Its Ability to Break Down Plant Cell Wall Components
  10. Identification of Protein Kinase C Activation as a Novel Mechanism for RGS2 Protein Upregulation through Phenotypic Screening of Natural Product Extracts
  11. Correction to “Baulamycins A and B, Broad-Spectrum Antibiotics Identified as Inhibitors of Siderophore Biosynthesis in Staphylococcus aureus and Bacillus anthracis”
  12. Identification of polyphenols from antiviral Chamaecrista nictitans extract using high-resolution LC–ESI–MS/MS
  13. Baulamycins A and B, Broad-Spectrum Antibiotics Identified as Inhibitors of Siderophore Biosynthesis in Staphylococcus aureus and Bacillus anthracis
  14. Isolation of Major Components from the Roots of Godmania aesculifolia and Determination of Their Antifungal Activities
  15. Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor
  16. Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300
  17. Phenolic compounds as antiangiogenic CMG2 inhibitors from costa rican endophytic fungi1
  18. Inhibition of Tumor Cells Interacting with Stromal Cells by Xanthones Isolated from a Costa Rican Penicillium sp.
  19. A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity
  20. Titration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase Inhibitors
  21. Complementary Cell-Based High-Throughput Screens Identify Novel Modulators of the Unfolded Protein Response
  22. Subcutaneous antifungal screening of Latin American plant extracts againstSporothrix schenckiiandFonsecaea pedrosoi
  23. Asterogynins: Secondary Metabolites from a Costa Rican Endophytic Fungus
  24. Screening of Latin American plants for antiparasitic activities against malaria, Chagas disease, and leishmaniasis
  25. Value of the ethnomedical information for the discovery of plants with antifungal properties. A survey among seven Latin American countries
  26. Study of the diversity of culturable actinomycetes in the North Pacific and Caribbean coasts of Costa Rica
  27. Molecular data indicate that Rhytidhysteron rufulum (ascomycetes, Patellariales) in Costa Rica consists of four distinct lineages corroborated by morphological and chemical characters
  28. Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite
  29. The Sorcerer II Global Ocean Sampling Expedition: Northwest Atlantic through Eastern Tropical Pacific
  30. Screening of Latin American Plants for Cytotoxic Activity
  31. Unusual Microbial Xylanases from Insect Guts
  32. Natural product based inhibitors of the thioredoxin–thioredoxin reductase system
  33. SEPARATION OF CRUDE PLANT EXTRACTS WITH HIGH SPEED CCC FOR PRIMARY SCREENING IN DRUG DISCOVERY
  34. Germacranolides from Mikania guaco
  35. β-Carboline monoterpenoid glucosides from Palicourea adusta
  36. Kaurene diterpenes from Mikania vitifolia
  37. Potent nor-triterpenoid blockers of the voltage-gated potassium channel Kv1.3 from Spachea correae
  38. Diterpenes and sesquiterpenes from Mikania banisteriae
  39. (+)-α-copaen-8-one and other constituents from Neomirandea species
  40. Diterpenes from Fleischmannia hymenophylla and Brickellia laciniata
  41. Ent-Clerodane derivatives from Chromolaena connivens
  42. Ent-clerodane derivatives and other constituents from representatives of the subgenus Ageratina
  43. Heliangolides from Viguiera sylvatica
  44. Sesquiterpene lactones and other constituents from Calea prunifolia and C. Peckii
  45. Clibadiolide, a sesquiterpene lactone esterified with a homoditerpene from Clibadium pittierii
  46. Germacranolides and other constituents from Ageratina species
  47. Seco-manool and other constituents from Fleischmannia microstemon