All Stories

  1. Lipid transport across the mycobacterial cell envelope

    Article • IUCrJ, September 2021, International Union of Crystallography

    Dr Ghader Bashiri

  2. Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

    Article • Nature Communications, October 2019, Springer Science + Business Media

    Dr Ghader Bashiri

  3. The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe–2S cluster

    Article • Journal of Biological Chemistry, July 2019, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Ghader Bashiri

  4. A revised biosynthetic pathway for the cofactor F420 in prokaryotes

    Article • Nature Communications, April 2019, Springer Science + Business Media

    Dr Colin Scott, Dr Ghader Bashiri

  5. A revised biosynthetic pathway for the cofactor F420 in bacteria

    Article • November 2018, Cold Spring Harbor Laboratory Press

    Dr Ghader Bashiri, Dr Colin Scott

  6. Biosynthesis of the Thiopeptins and Identification of an F420H2-Dependent Dehydropiperidine Reductase

    Article • Journal of the American Chemical Society, August 2018, American Chemical Society (ACS)

    Dr Ghader Bashiri

  7. Development of NMR and thermal shift assays for the evaluation ofMycobacterium tuberculosisisocitrate lyase inhibitors

    Article • MedChemComm, January 2017, Royal Society of Chemistry

    Dr Ghader Bashiri

  8. Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis

    Article • FEBS Open Bio, October 2016, Wiley

    Dr Ghader Bashiri

  9. A NADH-accepting imine reductase variant: Immobilization and cofactor regeneration by oxidative deamination

    Article • Journal of Biotechnology, July 2016, Elsevier

    Dr Ghader Bashiri

  10. Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms

    Article • Structure, July 2016, Elsevier

    Dr Ghader Bashiri

  11. Elongation of the Poly-γ-glutamate Tail of F420Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) ofMycobacterium tuberculosis

    Article • Journal of Biological Chemistry, February 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Ghader Bashiri

  12. PdxH proteins of mycobacteria are typical members of the classical pyridoxine/pyridoxamine 5′-phosphate oxidase family

    Article • FEBS Letters, February 2016, Wiley

    Dr Ghader Bashiri

  13. Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex

    Article • Acta Crystallographica Section D Biological Crystallography, October 2015, International Union of Crystallography

    Dr Ghader Bashiri, Shaun Lott

  14. Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44

    Article • Journal of Biological Chemistry, June 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Ghader Bashiri

  15. A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    Dr Ghader Bashiri, Shaun Lott

  16. Use of a “silver bullet” to resolve crystal lattice dislocation disorder: A cobalamin complex of Δ1-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis

    Article • Journal of Structural Biology, February 2015, Elsevier

    Dr Ghader Bashiri

  17. Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein

    Article • Journal of Structural Biology, December 2014, Elsevier

    Dr Ghader Bashiri

  18. Production of recombinant proteins inMycobacterium smegmatisfor structural and functional studies

    Article • Protein Science, November 2014, Wiley

    Dr Ghader Bashiri

  19. Characterization of the proline-utilization pathway inMycobacterium tuberculosisthrough structural and functional studies

    Article • Acta Crystallographica Section D Biological Crystallography, March 2014, International Union of Crystallography

    Dr Ghader Bashiri, Edward Baker

  20. Uncovering the Enzymes that Catalyze the Final Steps in Oxytetracycline Biosynthesis

    Article • Journal of the American Chemical Society, May 2013, American Chemical Society (ACS)

    Dr Ghader Bashiri

  21. Tat–Dependent Translocation of an F420–Binding Protein of Mycobacterium tuberculosis

    Article • PLoS ONE, October 2012, PLOS

    Dr Ghader Bashiri

  22. Cloning, expression, purification, crystallization and preliminary X-ray studies of the C-terminal domain of Rv3262 (FbiB) fromMycobacterium tuberculosis

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, September 2011, International Union of Crystallography

    Dr Ghader Bashiri

  23. Metabolic Engineering of Cofactor F420 Production in Mycobacterium smegmatis

    Article • PLoS ONE, December 2010, PLOS

    Dr Ghader Bashiri

  24. Comparative bioactivation of the novel anti-tuberculosis agent PA-824 in Mycobacteria and a subcellular fraction of human liver

    Article • British Journal of Pharmacology, December 2010, Wiley

    Dr Ghader Bashiri

  25. Crystal Structures of F420-dependent Glucose-6-phosphate Dehydrogenase FGD1 Involved in the Activation of the Anti-tuberculosis Drug Candidate PA-824 Reveal the Basis of Coenzyme and Substrate Binding

    Article • Journal of Biological Chemistry, April 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Ghader Bashiri

  26. A new Gateway® vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis

    Article • Protein Expression and Purification, January 2008, Elsevier

    Dr Ghader Bashiri, Shaun Lott

  27. Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system

    Article • Protein Expression and Purification, July 2007, Elsevier

    Dr Ghader Bashiri