All Stories

  1. Mechanical Power and Driving Pressure: Mechanisms of Lung Injury, Markers of Pathophysiology, or Therapeutic Targets?

    Article • Journal of Clinical Medicine, December 2025, MDPI AG

    Professor Gary F Nieman

  2. Computationally-directed mechanical ventilation in a porcine model of ARDS

    Article • Frontiers in Physiology, November 2025, Frontiers

    Professor Gary F Nieman

  3. Balancing the Scales: Using Ventilator Time to Counter Mass Loading

    Article • Journal of Applied Physiology, November 2025, American Physiological Society

    Professor Gary F Nieman

  4. Toward optimal mechanical ventilation of the injured lung: the role of expiratory duration

    Article • Critical Care, November 2025, Springer Science + Business Media

    Professor Gary F Nieman

  5. Comparison of early and late time-controlled adaptive ventilation on pulmonary gas exchange in anesthetized horses

    Article • Veterinary Anaesthesia and Analgesia, November 2025, Elsevier

    Professor Gary F Nieman

  6. The role of pulmonary surfactant on lung fluid balance

    Article • AJP Lung Cellular and Molecular Physiology, August 2025, American Physiological Society

    Professor Gary F Nieman

  7. Explosive Energy Bursts Linked to Ventilator-Induced Lung Injury

    Article • Proceedings of the National Academy of Sciences, March 2025, Proceedings of the National Academy of Sciences

    Donald Gaver, Professor Gary F Nieman

  8. Correction: Atelectrauma can be avoided if expiration is sufficiently brief: evidence from inverse modeling and oscillometry during airway pressure release ventilation

    Article • Critical Care, January 2025, Springer Science + Business Media

    Professor Gary F Nieman

  9. Meconium Influences Pulmonary Short-Chain Fatty Acid Concentration in Porcine Meconium Aspiration Model

    Article • Biomedicine Hub, December 2024, Karger Publishers

    Professor Gary F Nieman

  10. Atelectrauma can be avoided if expiration is sufficiently brief: evidence from inverse modeling and oscillometry during airway pressure release ventilation

    Article • Critical Care, October 2024, Springer Science + Business Media

    Professor Gary F Nieman

  11. Inconsistent Methods Used to Set Airway Pressure Release Ventilation in Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Regression Analysis

    Article • Journal of Clinical Medicine, May 2024, MDPI AG

    Professor Gary F Nieman

  12. Mechanical Power and Ventilator-induced Lung Injury: What Does Physics Have to Say?

    Article • American Review of Respiratory Disease, April 2024, American Thoracic Society

    Professor Gary F Nieman

  13. The use of protective mechanical ventilation during extracorporeal membrane oxygenation for the treatment of acute respiratory failure

    Article • Perfusion, January 2024, SAGE Publications

    Professor Gary F Nieman

  14. Time-Controlled Adaptive Ventilation (TCAV): a personalized strategy for lung protection

    Article • Respiratory Research, January 2024, Springer Science + Business Media

    Professor Gary F Nieman

  15. Airway pressure release ventilation for lung protection in acute respiratory distress syndrome: an alternative way to recruit the lungs

    Article • Current Opinion in Critical Care, December 2023, Wolters Kluwer Health

    Professor Gary F Nieman

  16. Sustained vs. Intratidal Recruitment in the Injured Lung During Airway Pressure Release Ventilation: A Computational Modeling Perspective

    Article • Military Medicine, November 2023, Oxford University Press (OUP)

    Professor Gary F Nieman

  17. Ratchet recruitment in the acute respiratory distress syndrome: lessons from the newborn cry

    Article • Frontiers in Physiology, November 2023, Frontiers

    Professor Gary F Nieman

  18. Time Controlled Adaptive Ventilation/Airway Pressure Release Ventilation Can be Used Effectively in Patients With or at High Risk of Acute Respiratory Distress Syndrome “Time is the Soul of the World” Pythagoras

    Article • Critical Care Medicine, August 2023, Wolters Kluwer Health

    Professor Gary F Nieman

  19. First Stabilize and then Gradually Recruit: A Paradigm Shift in Protective Mechanical Ventilation for Acute Lung Injury

    Article • Journal of Clinical Medicine, July 2023, MDPI AG

    Professor Gary F Nieman

  20. Ventilator-Induced Lung Injury as a Dynamic Balance Between Epithelial Cell Damage and Recovery

    Article • Annals of Biomedical Engineering, March 2023, Springer Science + Business Media

    Professor Gary F Nieman

  21. Protective ventilation in a pig model of acute lung injury: timing is as important as pressure

    Article • Journal of Applied Physiology, November 2022, American Physiological Society

    Professor Gary F Nieman

  22. Editorial: Protecting the acutely injured lung: Physiologic, mechanical, inflammatory, and translational perspectives

    Article • Frontiers in Physiology, September 2022, Frontiers

    Professor Gary F Nieman

  23. Unshrinking the baby lung to calm the VILI vortex

    Article • Critical Care, August 2022, Springer Science + Business Media

    Professor Gary F Nieman

  24. Myths and Misconceptions of Airway Pressure Release Ventilation: Getting Past the Noise and on to the Signal

    Article • Frontiers in Physiology, July 2022, Frontiers

    Professor Gary F Nieman

  25. Effect of low dose acetylsalicylic acid and anticoagulant on clinical outcomes in COVID‐19, analytical cross‐sectional study

    Article • Health Science Reports, July 2022, Wiley

    Professor Gary F Nieman

  26. Electric Cell-Substrate Impedance Sensing (ECIS) as a Platform for Evaluating Barrier-Function Susceptibility and Damage from Pulmonary Atelectrauma

    Article • Biosensors, June 2022, MDPI AG

    Professor Gary F Nieman

  27. Nano-chemically Modified Tetracycline-3 (nCMT-3) Attenuates Acute Lung Injury via Blocking sTREM-1 Release and NLRP3 Inflammasome Activation

    Article • Shock, May 2022, Wolters Kluwer Health

    Professor Gary F Nieman

  28. Assessment of Heterogeneity in Lung Structure and Function During Mechanical Ventilation: A Review of Methodologies

    Article • Journal of Engineering and Science in Medical Diagnostics and Therapy, April 2022, ASME International

    Professor Gary F Nieman

  29. A Ventilator Mode Cannot Set Itself, Nor Can It Be Solely Responsible for Outcomes*

    Article • Critical Care Medicine, March 2022, Wolters Kluwer Health

    Professor Gary F Nieman

  30. Mechanical Ventilation in Pediatric and Neonatal Patients

    Article • Frontiers in Physiology, March 2022, Frontiers

    Professor Gary F Nieman

  31. Effects of time-controlled adaptive ventilation on cardiorespiratory parameters and inflammatory response in experimental emphysema

    Article • Journal of Applied Physiology, February 2022, American Physiological Society

    Professor Gary F Nieman

  32. Hemostatic shape memory polymer foams with improved survival in a lethal traumatic hemorrhage model

    Article • Acta Biomaterialia, January 2022, Elsevier

    Professor Gary F Nieman

  33. Airway Pressure Release Ventilation in Acute Respiratory Failure Due to COVID-19: When One Door Closes

    Article • Critical Care Medicine, December 2021, Wolters Kluwer Health

    Professor Gary F Nieman

  34. Pulmonary Interstitial Matrix and Lung Fluid Balance From Normal to the Acutely Injured Lung

    Article • Frontiers in Physiology, December 2021, Frontiers

    Professor Gary F Nieman

  35. Acetylsalicylic Acid Compared with Enoxaparin for the Prevention of Thrombosis and Mechanical Ventilation in COVID-19 Patients: A Retrospective Cohort Study

    Article • Clinical Drug Investigation, July 2021, Springer Science + Business Media

    Professor Gary F Nieman

  36. Rationales and uncertainties for aspirin use in COVID-19: a narrative review

    Article • Family Medicine and Community Health, April 2021, BMJ

    Professor Gary F Nieman

  37. Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications

    Article • Journal of Applied Physiology, March 2021, American Physiological Society

    Professor Gary F Nieman

  38. Atelectrauma Versus Volutrauma: A Tale of Two Time-Constants

    Article • Critical Care Explorations, December 2020, Wolters Kluwer Health

    Professor Gary F Nieman

  39. Time-Controlled Adaptive Ventilation Versus Volume-Controlled Ventilation in Experimental Pneumonia

    Article • Critical Care Medicine, October 2020, Wolters Kluwer Health

    Professor Gary F Nieman

  40. The POOR Get POORer: A Hypothesis for the Pathogenesis of Ventilator-induced Lung Injury

    Article • American Review of Respiratory Disease, October 2020, American Thoracic Society

    Professor Gary F Nieman

  41. Ventilating Two Subjects with One Ventilator: Achievable but not Advisable

    Article • April 2020, Springer Science + Business Media

    Professor Gary F Nieman

  42. Mechanical Ventilation Lessons Learned From Alveolar Micromechanics

    Article • Frontiers in Physiology, March 2020, Frontiers

    Professor Gary F Nieman

  43. A Physiologically Informed Strategy to Effectively Open, Stabilize, and Protect the Acutely Injured Lung

    Article • Frontiers in Physiology, March 2020, Frontiers

    Professor Gary F Nieman

  44. Prevention and treatment of acute lung injury with time-controlled adaptive ventilation: physiologically informed modification of airway pressure release ventilation

    Article • Annals of Intensive Care, January 2020, Springer Science + Business Media

    Professor Gary F Nieman

  45. Surfactant delivery in rat lungs: Comparing 3D geometrical simulation model with experimental instillation

    Article • PLoS Computational Biology, October 2019, PLOS

    Marcel Filoche, Professor Gary F Nieman

  46. It Is Time to Treat the Patient and Not Just the Ventilator

    Article • Critical Care Medicine, August 2019, Wolters Kluwer Health

    Professor Gary F Nieman

  47. Time-controlled adaptive ventilation (TCAV) accelerates simulated mucus clearance via increased expiratory flow rate

    Article • Intensive Care Medicine Experimental, May 2019, Springer Science + Business Media

    Professor Gary F Nieman

  48. The time-controlled adaptive ventilation protocol: mechanistic approach to reducing ventilator-induced lung injury

    Article • European Respiratory Review, April 2019, European Respiratory Society (ERS)

    Professor Gary F Nieman

  49. Preemptive mechanical ventilation based on dynamic physiology in the alveolar microenvironment: Novel considerations of time-dependent properties of the respiratory system

    Article • Journal of Trauma and Acute Care Surgery, December 2018, Wolters Kluwer Health

    Professor Gary F Nieman

  50. Enteral administration of bacteria fermented formula in newborn piglets: A high fidelity model for necrotizing enterocolitis (NEC)

    Article • PLOS One, July 2018, PLOS

    Professor Gary F Nieman

  51. Biological Response to Time-Controlled Adaptive Ventilation Depends on Acute Respiratory Distress Syndrome Etiology*

    Article • Critical Care Medicine, June 2018, Wolters Kluwer Health

    Professor Gary F Nieman

  52. Acute lung injury: how to stabilize a broken lung

    Article • Critical Care, May 2018, Springer Science + Business Media

    Professor Gary F Nieman

  53. Last Word on Viewpoint: Looking beyond macrovenitlatory parameters and rethinking ventilator-induced lung injury

    Article • Journal of Applied Physiology, May 2018, American Physiological Society

    Professor Gary F Nieman

  54. Looking beyond macroventilatory parameters and rethinking ventilator-induced lung injury

    Article • Journal of Applied Physiology, May 2018, American Physiological Society

    Professor Gary F Nieman

  55. Excessive Extracellular ATP Desensitizes P2Y2 and P2X4 ATP Receptors Provoking Surfactant Impairment Ending in Ventilation-Induced Lung Injury

    Article • International Journal of Molecular Sciences, April 2018, MDPI AG

    MD TORU KOTANI, Professor Gary F Nieman

  56. Reply to Drs. Monjezi and Jamaati: Dynamic alveolar mechanics are more than a soap bubble on a capillary tube

    Article • Journal of Applied Physiology, February 2018, American Physiological Society

    Professor Gary F Nieman

  57. Physiology in Medicine: Understanding dynamic alveolar physiology to minimize ventilator-induced lung injury

    Article • Journal of Applied Physiology, June 2017, American Physiological Society

    Professor Gary F Nieman

  58. Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury

    Article • Purinergic Signalling, May 2017, Springer Science + Business Media

    Professor Gary F Nieman

  59. The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model

    Article • Intensive Care Medicine Experimental, May 2017, Springer Science + Business Media

    Professor Gary F Nieman

  60. Personalizing mechanical ventilation according to physiologic parameters to stabilize alveoli and minimize ventilator induced lung injury (VILI)

    Article • Intensive Care Medicine Experimental, February 2017, Springer Science + Business Media

    Professor Gary F Nieman

  61. Limiting ventilator-associated lung injury in a preterm porcine neonatal model

    Article • Journal of Pediatric Surgery, January 2017, Elsevier

    Professor Gary F Nieman

  62. Onset of Inflammation With Ischemia: Implications for Donor Lung Preservation and Transplant Survival

    Article • Arabian archaeology and epigraphy, September 2016, Elsevier

    Professor Gary F Nieman

  63. Lung stress, strain, and energy load: engineering concepts to understand the mechanism of ventilator-induced lung injury (VILI)

    Article • Intensive Care Medicine Experimental, June 2016, Springer Science + Business Media

    Professor Gary F Nieman

  64. The 30-year evolution of airway pressure release ventilation (APRV)

    Article • Intensive Care Medicine Experimental, May 2016, Springer Science + Business Media

    Professor Gary F Nieman

  65. “Open the lung and keep it open”: a homogeneously ventilated lung is a ‘healthy lung’

    Article • Annals of Translational Medicine, April 2016, AME Publishing Company

    Professor Gary F Nieman

  66. DIFFERENTIAL SUSCEPTIBILITY OF HUMAN SP-B GENETIC VARIANTS ON LUNG INJURY CAUSED BY BACTERIAL PNEUMONIA AND THE EFFECT OF A CHEMICALLY MODIFIED CURCUMIN

    Article • Shock, April 2016, Wolters Kluwer Health

    Professor Gary F Nieman

  67. ARDS: what experimental models have taught us

    Article • Intensive Care Medicine, February 2016, Springer Science + Business Media

    Professor Gary F Nieman

  68. Preemptive mechanical ventilation can block progressive acute lung injury

    Article • World Journal of Critical Care Medicine, January 2016, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor Gary F Nieman

  69. Effect of Airway Pressure Release Ventilation on Dynamic Alveolar Heterogeneity

    Article • JAMA Surgery, January 2016, American Medical Association (AMA)

    Professor Gary F Nieman

  70. Protecting lungs with acute lung injury

    Article • Journal of Applied Physiology, December 2015, American Physiological Society

    Professor Gary F Nieman

  71. RETRACTED: Mechanical Ventilation as a Therapeutic Tool to Reduce ARDS Incidence

    Article • CHEST Journal, December 2015, Elsevier

    Professor Gary F Nieman

  72. The effects of airway pressure release ventilation on respiratory mechanics in extrapulmonary lung injury

    Article • Intensive Care Medicine Experimental, December 2015, Springer Science + Business Media

    Professor Gary F Nieman

  73. Alveolar instability (atelectrauma) is not identified by arterial oxygenation predisposing the development of an occult ventilator-induced lung injury

    Article • Intensive Care Medicine Experimental, June 2015, Springer Science + Business Media

    Professor Gary F Nieman

  74. Trauma in silico: Individual-specific mathematical models and virtual clinical populations

    Article • Science Translational Medicine, April 2015, American Association for the Advancement of Science

    Professor Gary F Nieman

  75. Predicting the response of the injured lung to the mechanical breath profile

    Article • Journal of Applied Physiology, April 2015, American Physiological Society

    Professor Gary F Nieman

  76. Commentaries on Viewpoint: The ongoing need for good physiological investigation: Obstructive sleep apnea in HIV patients as a paradigmCommentaries on Viewpoint: The ongoing need for good physiological investigation: Obstructive sleep apnea in HIV pati...

    Article • Journal of Applied Physiology, January 2015, American Physiological Society

    MD, PhD Jaime L Eugenín, Peter Kerkhof, Professor Gary F Nieman

  77. Electroporation-Mediated Gene Delivery of Na+,K+-ATPase, and ENaC Subunits to the Lung Attenuates Acute Respiratory Distress Syndrome in a Two-Hit Porcine Model

    Article • Shock, January 2015, Wolters Kluwer Health

    Professor Gary F Nieman

  78. Response to letter by Dr. M. S. A. Mohamed (Antagonizing reactive oxygen species during lung perfusion)

    Article • AJP Lung Cellular and Molecular Physiology, December 2014, American Physiological Society

    Professor Gary F Nieman

  79. Mechanical Breath Profile of Airway Pressure Release Ventilation

    Article • JAMA Surgery, November 2014, American Medical Association (AMA)

    Professor Gary F Nieman

  80. Airway Pressure Release Ventilation Reduces Conducting Airway Micro-Strain in Lung Injury

    Article • Journal of the American College of Surgeons, November 2014, Wolters Kluwer Health

    Professor Gary F Nieman

  81. Shear stress-related mechanosignaling with lung ischemia: lessons from basic research can inform lung transplantation

    Article • AJP Lung Cellular and Molecular Physiology, November 2014, American Physiological Society

    Professor Gary F Nieman

  82. Removal of Inflammatory Ascites Is Associated With Dynamic Modification of Local and Systemic Inflammation Along With Prevention of Acute Lung Injury

    Article • Shock, April 2014, Wolters Kluwer Health

    Professor Gary F Nieman

  83. Airway Pressure Release Ventilation Prevents Ventilator-Induced Lung Injury in Normal Lungs

    Article • JAMA Surgery, November 2013, American Medical Association (AMA)

    Professor Gary F Nieman

  84. Early application of airway pressure release ventilation may reduce mortality in high-risk trauma patients

    Article • Journal of Trauma and Acute Care Surgery, October 2013, Wolters Kluwer Health

    Professor Gary F Nieman

  85. Is Time the Missing Component in Protective Ventilation Strategies?*

    Article • Critical Care Medicine, October 2013, Wolters Kluwer Health

    Professor Gary F Nieman

  86. Preemptive Application of Airway Pressure Release Ventilation Prevents Development of Acute Respiratory Distress Syndrome in a Rat Traumatic Hemorrhagic Shock Model

    Article • Shock, September 2013, Wolters Kluwer Health

    Professor Gary F Nieman

  87. Bayesian inference of the lung alveolar spatial model for the identification of alveolar mechanics associated with acute respiratory distress syndrome

    Article • Physical Biology, April 2013, Institute of Physics Publishing

    Professor Gary F Nieman

  88. EARLY AIRWAY PRESSURE RELEASE VENTILATION PREVENTS ARDS—A NOVEL PREVENTIVE APPROACH TO LUNG INJURY

    Article • Shock, January 2013, Wolters Kluwer Health

    Professor Gary F Nieman

  89. Commentaries on Viewpoint: Unresolved mysteries

    Article • Journal of Applied Physiology, December 2012, American Physiological Society

    Professor Dmitriy A Yablonskiy, Professor Gary F Nieman

  90. Early stabilizing alveolar ventilation prevents acute respiratory distress syndrome

    Article • Journal of Trauma and Acute Care Surgery, August 2012, Wolters Kluwer Health

    Professor Gary F Nieman

  91. Lung recruitment

    Article • Critical Care Medicine, June 2012, Wolters Kluwer Health

    Professor Gary F Nieman

  92. Sepsis: Something old, something new, and a systems view

    Article • Journal of Critical Care, June 2012, Elsevier

    Professor Gary F Nieman

  93. Toward Computational Identification of Multiscale “Tipping Points” in Acute Inflammation and Multiple Organ Failure

    Article • Annals of Biomedical Engineering, April 2012, Springer Science + Business Media

    Professor Gary F Nieman

  94. A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine*

    Article • Critical Care Medicine, April 2012, Wolters Kluwer Health

    Professor Gary F Nieman

  95. Chemically Modified Tetracycline 3 Prevents Acute Respiratory Distress Syndrome in a Porcine Model of Sepsis + Ischemia/Reperfusion–Induced Lung Injury

    Article • Shock, April 2012, Wolters Kluwer Health

    Professor Gary F Nieman

  96. Amelia Earhart, alveolar mechanics, and other great mysteries

    Article • Journal of Applied Physiology, March 2012, American Physiological Society

    Professor Gary F Nieman

  97. Up in smoke

    Article • Critical Care Medicine, March 2012, Wolters Kluwer Health

    Professor Gary F Nieman

  98. Linking Inflammation, Cardiorespiratory Variability, and Neural Control in Acute Inflammation via Computational Modeling

    Article • Frontiers in Physiology, January 2012, Frontiers

    Professor Gary F Nieman

  99. Lung injury induced by sepsis: lessons learned from large animal models and future directions for treatment

    Article • Expert Review of Anti-infective Therapy, December 2011, Taylor & Francis

    Professor Gary F Nieman

  100. Jack of all trades: Pleiotropy and the application of chemically modified tetracycline-3 in sepsis and the acute respiratory distress syndrome (ARDS)

    Article • Pharmacological Research, December 2011, Elsevier

    Professor Gary F Nieman

  101. A Clinically Applicable Porcine Model of Septic and Ischemia/Reperfusion-Induced Shock and Multiple Organ Injury

    Article • Journal of Surgical Research, March 2011, Elsevier

    Professor Gary F Nieman

  102. Comparison of “Open Lung” Modes with Low Tidal Volumes in a Porcine Lung Injury Model

    Article • Journal of Surgical Research, March 2011, Elsevier

    Professor Gary F Nieman

  103. Continuous elevation of lung sound amplitudes, recorded at fixed flow rate, may indicate an increase in lung water content

    Article • Critical Care, February 2011, Springer Science + Business Media

    Professor Gary F Nieman

  104. Peritoneal Negative Pressure Therapy Prevents Multiple Organ Injury in a Chronic Porcine Sepsis and Ischemia/Reperfusion Model

    Article • Shock, November 2010, Wolters Kluwer Health

    Professor Gary F Nieman

  105. Titration of Mean Airway Pressure and FiO2 During High Frequency Oscillatory Ventilation in a Porcine Model of Acute Lung Injury

    Article • Journal of Surgical Research, November 2010, Elsevier

    Professor Gary F Nieman

  106. Loss of Airway Pressure During HFOV Results in an Extended Loss of Oxygenation: A Retrospective Animal Study

    Article • Journal of Surgical Research, August 2010, Elsevier

    Professor Gary F Nieman

  107. Plateau and Transpulmonary Pressure With Elevated Intra-Abdominal Pressure or Atelectasis

    Article • Journal of Surgical Research, March 2010, Elsevier

    Professor Gary F Nieman

  108. Dynamic alveolar mechanics in acute lung injury

    Article • Critical Care Medicine, January 2010, Wolters Kluwer Health

    Professor Gary F Nieman

  109. The role of time and pressure on alveolar recruitment

    Article • Journal of Applied Physiology, March 2009, American Physiological Society

    Professor Gary F Nieman

  110. An Official ATS Conference Proceedings: Advances in Small-Animal Imaging Application to Lung Pathophysiology

    Article • Proceedings of the American Thoracic Society, July 2008, American Thoracic Society

    Professor Gary F Nieman

  111. Clinically applicable porcine model of abdominal compartment syndrome

    Article • Critical Care, January 2008, Springer Science + Business Media

    Professor Gary F Nieman

  112. Negative pressure therapy improved outcome in a clinically applicable abdominal compartment syndrome porcine model

    Article • Critical Care, January 2008, Springer Science + Business Media

    Professor Gary F Nieman

  113. Alveolar instability caused by mechanical ventilation initially damages the nondependent normal lung

    Article • Critical Care, September 2007, Springer Science + Business Media

    Professor Gary F Nieman

  114. Using pressure–volume curves to set proper PEEP in acute lung injury

    Article • Nursing in Critical Care, August 2007, Wiley

    Professor Gary F Nieman

  115. Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics

    Article • Critical Care, June 2007, Springer Science + Business Media

    Professor Gary F Nieman

  116. Correlation between alveolar recruitment /derecruitment and inflection points on the pressure-volume curve

    Article • Intensive Care Medicine, May 2007, Springer Science + Business Media

    Professor Gary F Nieman

  117. Effect of positive end-expiratory pressure and tidal volume on lung injury induced by alveolar instability

    Article • Critical Care, February 2007, Springer Science + Business Media

    Professor Gary F Nieman

  118. A 4-Dimensional Model of the Alveolar Structure

    Article • The Journal of Physiological Sciences, January 2007, Physiological Society of Japan

    Professor Gary F Nieman

  119. Absence of Alveolar Tears in Rat Lungs with Significant Alveolar Instability

    Article • Respiration, January 2007, Karger Publishers

    Professor Gary F Nieman

  120. CHEMICALLY MODIFIED TETRACYCLINE (COL-3) IMPROVES SURVIVAL IF GIVEN 12 BUT NOT 24 HOURS AFTER CECAL LIGATION AND PUNCTURE

    Article • Shock, December 2006, Wolters Kluwer Health

    Professor Gary F Nieman

  121. Chemically Modified Tetracycline Improves Contractility in Porcine Coronary Ischemia/Reperfusion Injury

    Article • Journal of Cardiac Surgery, May 2006, Hindawi Publishing Corporation

    Professor Gary F Nieman

  122. Can Systemic Diseases Co-induce (Not Just Exacerbate) Periodontitis? A Hypothetical “Two-hit” Model

    Article • Journal of Dental Research, February 2006, SAGE Publications

    Professor Gary F Nieman

  123. Can ventilator mode reduce ventilator-induced lung injury?*

    Article • Critical Care Medicine, February 2006, Wolters Kluwer Health

    Professor Gary F Nieman

  124. Dynamic alveolar mechanics in four models of lung injury

    Article • Intensive Care Medicine, December 2005, Springer Science + Business Media

    Professor Gary F Nieman

  125. CHEMICALLY MODIFIED TETRACYCLINE PREVENTS THE DEVELOPMENT OF SEPTIC SHOCK AND ACUTE RESPIRATORY DISTRESS SYNDROME IN A CLINICALLY APPLICABLE PORCINE MODEL

    Article • Shock, October 2005, Wolters Kluwer Health

    Professor Gary F Nieman

  126. Pulmonary impedance and alveolar instability during injurious ventilation in rats

    Article • Journal of Applied Physiology, August 2005, American Physiological Society

    Professor Gary F Nieman

  127. Dynamic alveolar mechanics and ventilator-induced lung injury

    Article • Critical Care Medicine, March 2005, Wolters Kluwer Health

    Professor Gary F Nieman

  128. THE DEVELOPMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AFTER GUT ISCHEMIA/REPERFUSION INJURY FOLLOWED BY FECAL PERITONITIS IN PIGS: A CLINICALLY RELEVANT MODEL

    Article • Shock, February 2005, Wolters Kluwer Health

    Professor Gary F Nieman

  129. Severity of Injury is Underestimated in the Absence of Autopsy Verification

    Article • Journal of Trauma and Acute Care Surgery, July 2004, Wolters Kluwer Health

    Professor Gary F Nieman

  130. Alveolar Instability Causes Early Ventilator-induced Lung Injury Independent of Neutrophils

    Article • American Review of Respiratory Disease, January 2004, American Thoracic Society

    Professor Gary F Nieman

  131. Positive End-Expiratory Pressure after a Recruitment Maneuver Prevents Both Alveolar Collapse and Recruitment/Derecruitment

    Article • American Review of Respiratory Disease, June 2003, American Thoracic Society

    Professor Gary F Nieman

  132. Metalloproteinase inhibition reduces lung injury and improves survival after cecal ligation and puncture in rats

    Article • Journal of Surgical Research, May 2003, Elsevier

    Professor Gary F Nieman

  133. Alveolar inflation during generation of a quasi-static pressure/volume curve in the acutely injured lung

    Article • Critical Care Medicine, April 2003, Wolters Kluwer Health

    Professor Gary F Nieman

  134. Tidal volume increases do not affect alveolar mechanics in normal lung but cause alveolar overdistension and exacerbate alveolar instability after surfactant deactivation

    Article • Critical Care Medicine, December 2002, Wolters Kluwer Health

    Professor Gary F Nieman

  135. Alveolar mechanics alter hypoxic pulmonary vasoconstriction*

    Article • Critical Care Medicine, June 2002, Wolters Kluwer Health

    Professor Gary F Nieman

  136. Invasive Arterial BP Monitoring in Trauma and Critical Care

    Article • CHEST Journal, October 2001, Elsevier

    Professor Gary F Nieman

  137. Metalloproteinase Inhibition Prevents Acute Respiratory Distress Syndrome

    Article • Journal of Surgical Research, August 2001, Elsevier

    Professor Gary F Nieman

  138. Visual Validation of the Mechanical Stabilizing Effects of Positive End-Expiratory Pressure at the Alveolar Level

    Article • Journal of Surgical Research, August 2001, Elsevier

    Professor Gary F Nieman

  139. Altered alveolar mechanics in the acutely injured lung

    Article • Critical Care Medicine, May 2001, Wolters Kluwer Health

    Professor Gary F Nieman

  140. A Role for the Anti-Inflammatory Properties of Tetracyclines in the Prevention of Acute Lung Injury

    Article • Current Medicinal Chemistry, February 2001, Bentham Science Publishers

    Professor Gary F Nieman

  141. The Mechanism of Lung Volume Change during Mechanical Ventilation

    Article • American Review of Respiratory Disease, November 1999, American Thoracic Society

    Professor Gary F Nieman

  142. Matrix Metalloproteinase Inhibitor Prevents Acute Lung Injury After Cardiopulmonary Bypass

    Article • Circulation, July 1999, Wolters Kluwer Health

    Professor Gary F Nieman

  143. Soluble Tumor Necrosis Factor Receptor Prevents Post-pump Syndrome

    Article • Journal of Surgical Research, May 1999, Elsevier

    Professor Gary F Nieman

  144. VIDEOMICROSCOPY PROVIDES ACCURATE IN VIVO ASSESSMENT OF PULMONARY MICROVASCULAR REACTIVITY IN RABBITS

    Article • Shock, May 1999, Wolters Kluwer Health

    Professor Gary F Nieman

  145. Multiple sequential insults cause post-pump syndrome

    Article • The Annals of Thoracic Surgery, April 1999, Elsevier

    Professor Gary F Nieman

  146. Aerosolized Surfactant Improves Pulmonary Function in Endotoxin-induced Lung Injury

    Article • American Review of Respiratory Disease, September 1998, American Thoracic Society

    Professor Gary F Nieman

  147. Endotoxin-stimulated alveolar macrophage recruitment of neutrophils and modulation with exogenous surfactant

    Article • Critical Care Medicine, August 1998, Wolters Kluwer Health

    Professor Gary F Nieman

  148. Exogenous surfactant and positive end-expiratory pressure in the treatment of endotoxin-induced lung injury

    Article • Critical Care Medicine, August 1998, Wolters Kluwer Health

    Professor Gary F Nieman

  149. Surfactant replacement in the treatment of sepsis-induced adult respiratory distress syndrome in pigs

    Article • Critical Care Medicine, June 1996, Wolters Kluwer Health

    Professor Gary F Nieman

  150. PULMONARY SURFACTANT FUNCTION FOLLOWING ENDOTOXIN

    Article • Shock, April 1996, Wolters Kluwer Health

    Professor Gary F Nieman

  151. Segmental pulmonary vascular resistance following wood smoke inhalation

    Article • Critical Care Medicine, July 1995, Wolters Kluwer Health

    Professor Gary F Nieman

  152. Effects of wood and cotton smoke on the surface properties of pulmonary surfactant

    Article • Respiration Physiology, June 1994, Elsevier

    Professor Gary F Nieman

  153. UNILATERAL SMOKE INHALATION INCREASES PULMONARY BLOOD FLOW TO THE INJURED LUNG

    Article • Journal of Trauma and Acute Care Surgery, May 1994, Wolters Kluwer Health

    Professor Gary F Nieman

  154. Comparison of high-frequency jet to conventional mechanical ventilation in the treatment of severe smoke inhalation injury

    Article • Burns, April 1994, Elsevier

    Professor Gary F Nieman

  155. Exosurf treatment following wood smoke inhalation

    Article • Burns, October 1993, Elsevier

    Professor Gary F Nieman

  156. Methylprednisolone does not protect the lung from inhalation injury

    Article • Burns, October 1991, Elsevier

    Professor Gary F Nieman

  157. Distribution of extravascular lung water after acute smoke inhalation

    Article • Journal of Applied Physiology, June 1990, American Physiological Society

    Professor Gary F Nieman

  158. Smoke inhalation

    Article • Burns, December 1988, Elsevier

    Professor Gary F Nieman

  159. Effects of Crystalloid on Lung Fluid Balance After Smoke Inhalation

    Article • Annals of Surgery, July 1988, Wolters Kluwer Health

    Professor Gary F Nieman

  160. Effect of increased alveolar surface tension on segmental pulmonary vascular resistance

    Article • Journal of Applied Physiology, January 1988, American Physiological Society

    Professor Gary F Nieman

  161. Surfactant displacement by meconium free fatty acids: An alternative explanation for atelectasis in meconium aspiration syndrome

    Article • The Journal of Pediatrics, May 1987, Elsevier

    Professor Gary F Nieman

  162. Effects of lung volume and alveolar surface tension on pulmonary vascular resistance

    Article • Journal of Applied Physiology, April 1987, American Physiological Society

    Professor Gary F Nieman

  163. Microvascular membrane permeability in high surface tension pulmonary edema

    Article • Journal of Applied Physiology, January 1986, American Physiological Society

    Professor Gary F Nieman

  164. High surface tension pulmonary edema induced by detergent aerosol

    Article • Journal of Applied Physiology, January 1985, American Physiological Society

    Professor Gary F Nieman

  165. High-frequency jet ventilation versus conventional ventilation after surfactant displacement in dogs

    Article • Critical Care Medicine, September 1984, Wolters Kluwer Health

    Professor Gary F Nieman

  166. High surface tension pulmonary edema

    Article • Journal of Surgical Research, June 1983, Elsevier

    Professor Gary F Nieman

  167. Alveolar function following surfactant deactivation

    Article • Journal of Applied Physiology, October 1981, American Physiological Society

    Professor Gary F Nieman

  168. The Effect of Smoke Inhalation on Pulmonary Surfactant

    Article • Annals of Surgery, February 1980, Wolters Kluwer Health

    Professor Gary F Nieman

  169. Inhalation of cannabis smoke in rats

    Article • Pharmacology Biochemistry and Behavior, July 1973, Elsevier

    Professor Gary F Nieman