All Stories

  1. Expansion of the TLO gene family enhances the virulence of Candida species

    Article • PLoS ONE, July 2018, PLOS

    Prof Gary P Moran

  2. Candida albicans hyphal expansion causes phagosomal membrane damage and luminal alkalinization

    Article • June 2018, Cold Spring Harbor Laboratory Press

    Prof Gary P Moran

  3. The Microbiome of Potentially Malignant Oral Leukoplakia Exhibits Enrichment for Fusobacterium, Leptotrichia, Campylobacter, and Rothia Species

    Article • Frontiers in Microbiology, December 2017, Frontiers

    Prof Gary P Moran

  4. The Candida albicans TOR-Activating GTPases Gtr1 and Rhb1 Coregulate Starvation Responses and Biofilm Formation

    Article • mSphere, November 2017, ASM Journals

    Prof Gary P Moran

  5. Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition

    Article • Proceedings of the National Academy of Sciences, May 2017, Proceedings of the National Academy of Sciences

    Prof Gary P Moran

  6. Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp.

    Article • PLoS Genetics, October 2016, PLOS

    Prof Gary P Moran

  7. ThePorphyromonas gingivalishemagglutinins HagB and HagC are major mediators of adhesion and biofilm formation

    Article • Molecular Oral Microbiology, February 2016, Wiley

    Prof Gary P Moran

  8. The Histone-Deacetylase-Inhibitor Suberoylanilide Hydroxamic Acid Promotes Dental Pulp Repair Mechanisms Through Modulation of Matrix Metalloproteinase-13 Activity

    Article • Journal of Cellular Physiology, December 2015, Wiley

    Prof Gary P Moran

  9. Candida albicans exhibits enhanced alkaline and temperature induction of Efg1-regulated transcripts relative to Candida dubliniensis

    Article • Genomics Data, December 2015, Elsevier

    Prof Gary P Moran

  10. Transcriptional profiling of suberoylanilide hydroxamic acid (SAHA) regulated genes in mineralizing dental pulp cells at early and late time points

    Article • Genomics Data, September 2015, Elsevier

    Prof Gary P Moran

  11. Telomeric ORFS in Candida albicans: Does Mediator Tail Wag the Yeast?

    Article • PLoS Pathogens, February 2015, PLOS

    Prof Gary P Moran

  12. Anin vivocomparison of internal bacterial colonization in two dental implant systems: Identification of a pathogenic reservoir

    Article • Acta Odontologica Scandinavica, November 2014, Informa Healthcare

    Prof Gary P Moran

  13. Telomeric ORFs (TLOs) in Candida spp. Encode Mediator Subunits That Regulate Distinct Virulence Traits

    Article • PLoS Genetics, October 2014, PLOS

    Prof Gary P Moran, Dr Karsten Hokamp

  14. An Introduction to the Medically Important Candida Species

    Article • April 2014, ASM Journals

    Prof Gary P Moran

  15. Comparative adherence of Candida albicans and Candida dubliniensis to human buccal epithelial cells and extracellular matrix proteins

    Article • Medical Mycology, March 2014, Oxford University Press (OUP)

    David C Coleman, Prof Gary P Moran

  16. Biocompatibility effects of indirect exposure of base-metal dental casting alloys to a human-derived three-dimensional oral mucosal model

    Article • Journal of Dentistry, November 2013, Elsevier

    Prof Gary P Moran

  17. Response of Extraintestinal Pathogenic Escherichia coli to Human Serum Reveals a Protective Role for Rcs-Regulated Exopolysaccharide Colanic Acid

    Article • Infection and Immunity, October 2013, ASM Journals

    Prof Gary P Moran, Steve Smith

  18. Influence of S. mutans on Base-metal Dental Casting Alloy Toxicity

    Article • Journal of Dental Research, October 2012, SAGE Publications

    Prof Gary P Moran

  19. Transcript profiling reveals rewiring of iron assimilation gene expression in Candida albicans and C. dubliniensis

    Article • FEMS Yeast Research, September 2012, Oxford University Press (OUP)

    Prof Gary P Moran

  20. Influence of doxorubicin on fluconazole susceptibility and efflux pump gene expression of Candida dubliniensis

    Article • Medical Mycology, May 2012, Oxford University Press (OUP)

    Prof Gary P Moran

  21. Distribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda

    Article • Medical Mycology, April 2012, Oxford University Press (OUP)

    David C Coleman, Prof Gary P Moran

  22. Candida albicansversusCandida dubliniensis: Why IsC. albicansMore Pathogenic?

    Article • International Journal of Microbiology, January 2012, Hindawi Publishing Corporation

    David C Coleman, Prof Gary P Moran

  23. Base-metal dental casting alloy biocompatibility assessment using a human-derived three-dimensional oral mucosal model

    Article • Acta Biomaterialia, January 2012, Elsevier

    Prof Gary P Moran

  24. Development of a discriminatory biocompatibility testing model for non-precious dental casting alloys

    Article • Dental Materials, December 2011, Elsevier

    Prof Gary P Moran

  25. Fungal Infections of Humans

    Article • October 2011, Wiley

    Prof Gary P Moran

  26. Triclosan Antagonizes Fluconazole Activity against Candida albicans

    Article • Journal of Dental Research, October 2011, SAGE Publications

    David C Coleman, Prof Gary P Moran

  27. Effects of surface finishing conditions on the biocompatibility of a nickel–chromium dental casting alloy

    Article • Dental Materials, July 2011, Elsevier

    David C Coleman, Prof Gary P Moran

  28. The Candida albicans-Specific Gene EED1 Encodes a Key Regulator of Hyphal Extension

    Article • PLoS ONE, April 2011, PLOS

    Prof Gary P Moran

  29. Microbiological Screening of Irish Patients with Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Reveals Persistence of Candida albicans Strains, Gradual Reduction in Susceptibility to Azoles, and Incidences of Clinical Signs of Oral Can...

    Article • Journal of Clinical Microbiology, March 2011, ASM Journals

    David C Coleman, Prof Gary P Moran

  30. Differential virulence of Candida albicansandC. dubliniensis: A role for Tor1 kinase?

    Article • Virulence, January 2011, Taylor & Francis

    Prof Gary P Moran

  31. Comparative Genomics and the Evolution of Pathogenicity in Human Pathogenic Fungi

    Article • Eukaryotic Cell, November 2010, ASM Journals

    David C Coleman, Prof Gary P Moran

  32. Differential Filamentation of Candida albicans and Candida dubliniensis Is Governed by Nutrient Regulation of UME6 Expression

    Article • Eukaryotic Cell, July 2010, ASM Journals

    David C Coleman, Prof Gary P Moran

  33. Mechanisms of antifungal drug resistance inCandida dubliniensis

    Article • Future Microbiology, June 2010, Future Medicine

    David C Coleman, Prof Gary P Moran

  34. Comparison of two DNA microarrays for detection of plasmid-mediated antimicrobial resistance and virulence factor genes in clinical isolates of Enterobacteriaceae and non-Enterobacteriaceae

    Article • International Journal of Antimicrobial Agents, June 2010, Elsevier

    Prof Gary P Moran

  35. Longitudinal Genotyping of Candida dubliniensis Isolates Reveals Strain Maintenance, Microevolution, and the Emergence of Itraconazole Resistance

    Article • Journal of Clinical Microbiology, March 2010, ASM Journals

    Prof Gary P Moran

  36. Comparative Transcript Profiling of Candida albicans and Candida dubliniensis Identifies SFL2, a C. albicans Gene Required for Virulence in a Reconstituted Epithelial Infection Model

    Article • Eukaryotic Cell, December 2009, ASM Journals

    David C Coleman, Prof Gary P Moran

  37. Purification and germination of Candida albicans and Candida dubliniensis chlamydospores cultured in liquid media

    Article • FEMS Yeast Research, November 2009, Oxford University Press (OUP)

    David C Coleman, Prof Gary P Moran

  38. Molecular Epidemiology of Candida Species

    Article • September 2009, Springer Science + Business Media

    Prof Gary P Moran

  39. Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans

    Article • Genome Research, September 2009, Cold Spring Harbor Laboratory Press

    David C Coleman, Prof Gary P Moran

  40. Genetic Differences between Avian and Human Isolates of Candida dubliniensis

    Article • Emerging Infectious Diseases, September 2009, Centers for Disease Control and Prevention (CDC)

    David C Coleman, Prof Gary P Moran

  41. A Ser29Leu Substitution in the Cytosine Deaminase Fca1p Is Responsible for Clade-Specific Flucytosine Resistance in Candida dubliniensis

    Article • Antimicrobial Agents and Chemotherapy, August 2009, ASM Journals

    David C Coleman, Prof Gary P Moran

  42. Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress

    Article • Molecular Microbiology, March 2009, Wiley

    David C Coleman, Prof Gary P Moran

  43. The expression of genes involved in the ergosterol biosynthesis pathway inCandida albicansandCandida dubliniensisbiofilms exposed to fluconazole

    Article • Mycoses, March 2009, Wiley

    Prof Gary P Moran

  44. CYP56 (Dit2p) in Candida albicans: Characterization and Investigation of Its Role in Growth and Antifungal Drug Susceptibility

    Article • Antimicrobial Agents and Chemotherapy, July 2008, ASM Journals

    David C Coleman, Prof Gary P Moran

  45. Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans

    Article • BMC Microbiology, January 2008, Springer Science + Business Media

    Prof Gary P Moran

  46. Multilocus Sequence Typing Reveals that the Population Structure of Candida dubliniensis Is Significantly Less Divergent than That of Candida albicans

    Article • Journal of Clinical Microbiology, December 2007, ASM Journals

    David C Coleman, Prof Gary P Moran

  47. Differential regulation of the transcriptional repressor NRG1 accounts for altered host-cell interactions in Candida albicans and Candida dubliniensis

    Article • Molecular Microbiology, November 2007, Wiley

    David C Coleman, Prof Gary P Moran

  48. Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans

    Article • Fungal Genetics and Biology, September 2007, Elsevier

    David C Coleman, Prof Gary P Moran

  49. 8th ASM Conference on Candida and Candidiasis: Molecular Tools Provide Insights into Host–pathogen Interactions

    Article • Mycopathologia, July 2006, Springer Science + Business Media

    Prof Gary P Moran

  50. Fungal Diseases of Humans

    Article • December 2005, Wiley

    Prof Gary P Moran

  51. Candida dubliniensis: Ten years on

    Article • FEMS Microbiology Letters, December 2005, Oxford University Press (OUP)

    David C Coleman, Prof Gary P Moran

  52. Azole susceptibility and resistance in Candida dubliniensis

    Article • Biochemical Society Transactions, October 2005, Portland Press Ltd.

    Prof Gary P Moran

  53. Reduced Azole Susceptibility in Genotype 3 Candida dubliniensis Isolates Associated with Increased CdCDR1 and CdCDR2 Expression

    Article • Antimicrobial Agents and Chemotherapy, April 2005, ASM Journals

    Dominique Sanglard, David C Coleman, Prof Gary P Moran

  54. Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis

    Article • Microbiology, October 2004, Society for General Microbiology

    David C Coleman, Prof Gary P Moran

  55. Comparison of the epidemiology, drug resistance mechanisms, and virulence of and

    Article • FEMS Yeast Research, January 2004, Oxford University Press (OUP)

    David C Coleman, Prof Gary P Moran

  56. Molecular Mechanisms of Itraconazole Resistance in Candida dubliniensis

    Article • Antimicrobial Agents and Chemotherapy, August 2003, ASM Journals

    Dominique Sanglard, David C Coleman, Prof Gary P Moran

  57. The Candida dubliniensis CdCDR1 Gene Is Not Essential for Fluconazole Resistance

    Article • Antimicrobial Agents and Chemotherapy, September 2002, ASM Journals

    David C Coleman, Prof Gary P Moran

  58. MDR1-Mediated Drug Resistance inCandida dubliniensis

    Article • Antimicrobial Agents and Chemotherapy, December 2001, ASM Journals

    David C Coleman, Prof Gary P Moran

  59. Isogenic Strain Construction and Gene Targeting inCandida dubliniensis

    Article • Journal of Bacteriology, May 2001, ASM Journals

    David C Coleman, Prof Gary P Moran

  60. Candidiasis

    Article • AIDS, April 1997, Wolters Kluwer Health

    David C Coleman, Prof Gary P Moran

  61. Molecular genetic approaches to identification, epidemiology and taxonomy of non-albicans Candida species

    Article • Journal of Medical Microbiology, June 1996, Society for General Microbiology

    Prof Gary P Moran

  62. Analysis of Drug Resistance in Pathogenic Fungi

    Article • Wiley

    Prof Gary P Moran