All Stories

  1. Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNA
  2. Deep visual proteomics uncovers nociceptor diversity and pain targets
  3. Mechanically-gated currents in mouse sensory neurons lacking PIEZO2
  4. Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNA
  5. Cluster nanoarchitecture and structural diversity of PIEZO1 at rest and during activation in intact cells
  6. A specialized cold sensing system in the naked mole-rat
  7. Ultrasensitive proteomics uncovers nociceptor diversity and novel pain targets
  8. Mechanically-gated currents in mouse sensory neurons lacking PIEZO2
  9. Mechanosensitive PIEZO2 channels shape coronary artery development
  10. The mechanotransduction protein STOML3 is required for proprioceptor plasticity following peripheral nerve regeneration
  11. Mechanosensitive PIEZO2 channels shape coronary artery development
  12. Piezo2 voltage-block regulates mechanical pain sensitivity
  13. Liver-like glycogen metabolism supports glycolysis in naked mole-rat heart during ischaemia
  14. Touch sensation requires the mechanically gated ion channel ELKIN1
  15. Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
  16. Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
  17. Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception
  18. Touch receptor end-organ innervation and function requires sensory neuron expression of the transcription factor Meis2
  19. Touch receptor end-organ innervation and function requires sensory neuron expression of the transcription factor Meis2
  20. Prox2 and Runx3 vagal sensory neurons regulate esophageal motility
  21. Role of TMEM100 in mechanically insensitive nociceptor un-silencing
  22. Lack of evidence for participation of TMEM150C in sensory mechanotransduction
  23. Piezo2 voltage-block regulates mechanical pain sensitivity
  24. Prox2+ and Runx3+ neurons regulate esophageal motility
  25. Touch receptor end-organ innervation and function requires sensory neuron expression of the transcription factor Meis2
  26. Immune competence and spleen size scale with colony status in the naked mole-rat
  27. In memoriam: Stephen B. McMahon, PhD, FMedSci December 21, 1954 to October 9, 2021
  28. Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception
  29. SPFH protein cage — one ring to rule them all
  30. The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology
  31. A Role for STOML3 in Olfactory Sensory Transduction
  32. Cultural transmission of vocal dialect in the naked mole-rat
  33. A Sweet Story of Metabolic Innovation in the Naked Mole-Rat
  34. African Naked Mole-Rats Demonstrate Extreme Tolerance to Hypoxia and Hypercapnia
  35. Hearing and Vocalizations in the Naked Mole-Rat
  36. The Somatosensory World of the African Naked Mole-Rat
  37. USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans
  38. SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes
  39. William D. Willis, Jr, MD, PhD Memorial Lecture: The evolutionary history of nerve growth factor and nociception
  40. USH2A is a skin end-organ protein necessary for vibration sensing in mice and humans
  41. TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration
  42. Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms
  43. The Sensory Coding of Warm Perception
  44. Collagen Organization Within the Cartilage of Trpv4−/− Mice Studied with Two‐Photon Microscopy and Polarized Second Harmonic Generation
  45. Rapid molecular evolution of pain insensitivity in multiple African rodents
  46. Publisher Correction: Lipidome determinants of maximal lifespan in mammals
  47. The sensory coding of warm perception
  48. The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice
  49. The neural circuits of thermal perception
  50. Specialized mechanoreceptor systems in rodent glabrous skin
  51. Specialized mechanoreceptor systems in rodent glabrous skin
  52. Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells
  53. Voltage gating of mechanosensitive PIEZO channels
  54. Mechanoelectrical transduction in chondrocytes
  55. The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord
  56. Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
  57. Voltage-gating of mechanosensitive PIEZO channels
  58. Congenital deafness is associated with specific somatosensory deficits in adolescents
  59. Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
  60. Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System
  61. Lipidome determinants of maximal lifespan in mammals
  62. Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes
  63. Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity
  64. Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain
  65. Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat
  66. Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
  67. A Molecular Signature of Myalgia in Myotonic Dystrophy 2
  68. A Probabilistic Model for Estimating the Depth and Threshold Temperature of C-fiber Nociceptors
  69. ASICs and mammalian mechanoreceptor function
  70. Photoswitchable fatty acids enable optical control of TRPV1
  71. GABA Blocks Pathological but Not Acute TRPV1 Pain Signals
  72. PIEZO2 is required for mechanotransduction in human stem cell–derived touch receptors
  73. Piezo2 is the major transducer of mechanical forces for touch sensation in mice
  74. A somatosensory circuit for cooling perception in mice
  75. Sensory mechanotransduction at membrane-matrix interfaces
  76. Inhibition of c-Kit signaling is associated with reduced heat and cold pain sensitivity in humans
  77. Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch
  78. Pro‐neurotrophins, sortilin, and nociception
  79. Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination
  80. Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objects
  81. Subunit‐specific inhibition of acid sensing ion channels by stomatin‐like protein 1
  82. Nerve Growth Factor and Nociception: From Experimental Embryology to New Analgesic Therapy
  83. Natural Selection and Pain Meet at a Sodium Channel
  84. Stomatin-domain protein interactions with acid-sensing ion channels modulate nociceptor mechanosensitivity
  85. Hairy Sensation
  86. A stomatin dimer modulates the activity of acid-sensing ion channels
  87. Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1
  88. Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons
  89. Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: Comparative analysis using six species of bathyergidae
  90. A Genetic Basis for Mechanosensory Traits in Humans
  91. Stomatin-domain proteins
  92. Presynaptically Localized Cyclic GMP-Dependent Protein Kinase 1 Is a Key Determinant of Spinal Synaptic Potentiation and Pain Hypersensitivity
  93. The Transcription Factor c-Maf Controls Touch Receptor Development and Function
  94. Gαq/11 signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization
  95. The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat
  96. KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
  97. Erratum: Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
  98. Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons
  99. The Cav3.2 T-type calcium channel regulates temporal coding in mouse mechanoreceptors
  100. Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice
  101. The Molecular and Cellular Identity of Peripheral Osmoreceptors
  102. Functional Neurokinin and NMDA Receptor Activity in an Animal Naturally Lacking Substance P: The Naked Mole-Rat
  103. Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
  104. Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation
  105. RAPID REPORT: Anin vivotethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors
  106. Evidence for a protein tether involved in somatic touch
  107. Absence of Histamine-Induced Itch in the African Naked Mole-Rat and “Rescue” by Substance P
  108. Nociceptors: a phylogenetic view
  109. Peripheral sensitisation of nociceptors via G-proteindependent potentiation of mechanotransduction currents
  110. Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development
  111. Speed and Temperature Dependences of Mechanotransduction in Afferent Fibers Recorded From the Mouse Saphenous Nerve
  112. Stretching it for pain
  113. Selective Inflammatory Pain Insensitivity in the African Naked Mole-Rat (Heterocephalus glaber)
  114. Nociceptive Tuning by Stem Cell Factor/c-Kit Signaling
  115. Stomatin and Sensory Neuron Mechanotransduction
  116. Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury
  117. A stomatin-domain protein essential for touch sensation in the mouse
  118. Mechanosensitive currents in the neurites of cultured mouse sensory neurones
  119. A role for T-type Ca2+ channels in mechanosensation
  120. The high threshold mechanotransducer: A status report
  121. Chapter 13 Finding Sensory Neuron Mechanotransduction Components
  122. A plethora of painful molecules [Curr. Opin. Neuro. 14 (2004) 443]
  123. The sensory mechanotransduction ion channel ASIC2 (acid sensitive ion channel 2) is regulated by neurotrophin availability
  124. The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function
  125. The AMPA Receptor Subunits GluR-A and GluR-B Reciprocally Modulate Spinal Synaptic Plasticity and Inflammatory Pain
  126. Role of T-Type Calcium Current in Identified D-Hair Mechanoreceptor Neurons Studied In Vitro
  127. A plethora of painful molecules
  128. Mechanosensation and pain
  129. A T-type calcium channel required for normal function of a mammalian mechanoreceptor
  130. Identification of Caveolae-like Structures on the Surface of Intact Cells Using Scanning Force Microscopy
  131. cGMP-mediated signaling via cGKIα is required for the guidance and connectivity of sensory axons
  132. GFRα2/neurturin signalling regulates noxious heat transduction in isolectin B4-binding mouse sensory neurons
  133. Neurotrophin-4
  134. The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice
  135. Erratum: corrigendum: The mammalian sodium channel BNC1 is required for normal touch sensation
  136. The Homeodomain Factor Lbx1 Distinguishes Two Major Programs of Neuronal Differentiation in the Dorsal Spinal Cord
  137. Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons
  138. The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice
  139. BDNF but not NT-4 is required for normal flexion reflex plasticity and function
  140. Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin
  141. Lack of Neurotrophin-4 Causes Selective Structural and Chemical Deficits in Sympathetic Ganglia and Their Preganglionic Innervation
  142. Neurotrophins, nociceptors and pain
  143. The mammalian sodium channel BNC1 is required for normal touch sensation
  144. Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors
  145. Cellular Sources of Enhanced Brain-Derived Neurotrophic Factor Production in a Mouse Model of Allergic Inflammation Notice to Professional Recruitment and Announcement Advertisers
  146. Abundant Production of Brain-Derived Neurotrophic Factor by Adult Visceral Epithelia
  147. Isolectin B4-Positive and -Negative Nociceptors Are Functionally Distinct
  148. Stomatin, a MEC-2 Like Protein, Is Expressed by Mammalian Sensory Neurons
  149. Stability and plasticity of primary afferent projections following nerve regeneration and central degeneration
  150. A new role for neurotrophins: involvement of brain‐derived neurotrophic factor and neurotrophin‐4 in hair cycle control
  151. Neurotrophins: A Link between Airway Inflammation and Airway Smooth Muscle Contractility in Asthma?
  152. BDNF overexpression induces differential increases among subsets of sympathetic innervation in murine back skin
  153. A New Role for Neurotrophin-3
  154. Point Mutation in trkB Causes Loss of NT4-Dependent Neurons without Major Effects on Diverse BDNF Responses
  155. Neurotrophin-3 Involvement in the Regulation of Hair Follicle Morphogenesis
  156. A role for BDNF in mechanosensation
  157. Receptive Properties of Embryonic Chick Sensory Neurons Innervating Skin
  158. Severe neuropathies in mice with targeted mutations in the ErbB3 receptor
  159. Receptive Properties of Mouse Sensory Neurons Innervating Hairy Skin
  160. Neurotrophins Live or Let Die: Does p75NTR Decide?
  161. Maintenance of Modality-specific Connections in the Spinal Cord after Neonatal Nerve Growth Factor Deprivation
  162. Neurotrophins and the specification of neuronal phenotype
  163. Roles of neurotrophin-3 during early development of the peripheral nervous system
  164. Physiology of the Neurotrophins
  165. Specific Subtypes of Cutaneous Mechanoreceptors Require Neurotrophin-3 Following Peripheral Target Innervation
  166. Neurotrophic factors and pain
  167. Peripheral and Central Mechanisms of NGF-induced Hyperalgesia
  168. NMDA receptors and activity-dependent tuning of the receptive fields of spinal cord neurons
  169. Regulation of cutaneous C-fiber heat nociceptors by nerve growth factor in the developing rat
  170. An ultrastructural size principle
  171. Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli
  172. Nerve growth factor and nociception
  173. Central hyperexcitability triggered by noxious inputs
  174. Muscle Afferents Innervating Skin Form Somatotopically Appropriate Connections in the Adult Rat Dorsal Horn
  175. Regulation of myelinated nociceptor function by nerve growth factor in neonatal and adult rats
  176. Neonatal Anti-NGF Treatment Reduces the Aδ- and C-Fibre Evoked Vasodilator Responses in Rat Skin: Evidence That Nociceptor Afferents Mediate Antidromic Vasodilatation
  177. Regulation of Afferent Connectivity in the Adult Spinal Cord by Nerve Growth Factor
  178. Removing constraints on neural sprouting
  179. Dorsal Horn Plasticity Following Re-routeing of Peripheral Nerves: Evidence for Tissue-Specific Neurotrophic Influences from the Periphery
  180. Physiological properties of primary sensory neurons appropriately and inappropriately innervating skeletal muscle in adult rats
  181. Physiological properties of primary sensory neurons appropriately and inappropriately innervating skin in the adult rat
  182. Requirement for nerve growth factor in the development of myelinated nociceptors in vivo
  183. The consequences of long-term topical capsaicin application in the rat
  184. Increase of blood flow in skin and spinal cord following activation of small diameter primary afferents
  185. Quantitative analysis of peptide levels and neurogenic extravasation following regeneration of afferents to appropriate and inappropriate targets