All Stories

  1. Deep visual proteomics uncovers nociceptor diversity and pain targets
  2. Mechanically-gated currents in mouse sensory neurons lacking PIEZO2
  3. Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNA
  4. Cluster nanoarchitecture and structural diversity of PIEZO1 at rest and during activation in intact cells
  5. A specialized cold sensing system in the naked mole-rat
  6. Ultrasensitive proteomics uncovers nociceptor diversity and novel pain targets
  7. Mechanically-gated currents in mouse sensory neurons lacking PIEZO2
  8. Mechanosensitive PIEZO2 channels shape coronary artery development
  9. The mechanotransduction protein STOML3 is required for proprioceptor plasticity following peripheral nerve regeneration
  10. Mechanosensitive PIEZO2 channels shape coronary artery development
  11. Piezo2 voltage-block regulates mechanical pain sensitivity
  12. Liver-like glycogen metabolism supports glycolysis in naked mole-rat heart during ischaemia
  13. Touch sensation requires the mechanically gated ion channel ELKIN1
  14. Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
  15. Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
  16. Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception
  17. Touch receptor end-organ innervation and function requires sensory neuron expression of the transcription factor Meis2
  18. Touch receptor end-organ innervation and function requires sensory neuron expression of the transcription factor Meis2
  19. Prox2 and Runx3 vagal sensory neurons regulate esophageal motility
  20. Role of TMEM100 in mechanically insensitive nociceptor un-silencing
  21. Lack of evidence for participation of TMEM150C in sensory mechanotransduction
  22. Piezo2 voltage-block regulates mechanical pain sensitivity
  23. Prox2+ and Runx3+ neurons regulate esophageal motility
  24. Touch receptor end-organ innervation and function requires sensory neuron expression of the transcription factor Meis2
  25. Immune competence and spleen size scale with colony status in the naked mole-rat
  26. In memoriam: Stephen B. McMahon, PhD, FMedSci December 21, 1954 to October 9, 2021
  27. Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception
  28. SPFH protein cage — one ring to rule them all
  29. The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology
  30. A Role for STOML3 in Olfactory Sensory Transduction
  31. Cultural transmission of vocal dialect in the naked mole-rat
  32. A Sweet Story of Metabolic Innovation in the Naked Mole-Rat
  33. African Naked Mole-Rats Demonstrate Extreme Tolerance to Hypoxia and Hypercapnia
  34. Hearing and Vocalizations in the Naked Mole-Rat
  35. The Somatosensory World of the African Naked Mole-Rat
  36. USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans
  37. SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes
  38. William D. Willis, Jr, MD, PhD Memorial Lecture: The evolutionary history of nerve growth factor and nociception
  39. USH2A is a skin end-organ protein necessary for vibration sensing in mice and humans
  40. TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration
  41. Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms
  42. The Sensory Coding of Warm Perception
  43. Collagen Organization Within the Cartilage of Trpv4−/− Mice Studied with Two‐Photon Microscopy and Polarized Second Harmonic Generation
  44. Rapid molecular evolution of pain insensitivity in multiple African rodents
  45. Publisher Correction: Lipidome determinants of maximal lifespan in mammals
  46. The sensory coding of warm perception
  47. The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice
  48. The neural circuits of thermal perception
  49. Specialized mechanoreceptor systems in rodent glabrous skin
  50. Specialized mechanoreceptor systems in rodent glabrous skin
  51. Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells
  52. Voltage gating of mechanosensitive PIEZO channels
  53. Mechanoelectrical transduction in chondrocytes
  54. The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord
  55. Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
  56. Voltage-gating of mechanosensitive PIEZO channels
  57. Congenital deafness is associated with specific somatosensory deficits in adolescents
  58. Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
  59. Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System
  60. Lipidome determinants of maximal lifespan in mammals
  61. Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes
  62. Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity
  63. Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain
  64. Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat
  65. Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
  66. A Molecular Signature of Myalgia in Myotonic Dystrophy 2
  67. A Probabilistic Model for Estimating the Depth and Threshold Temperature of C-fiber Nociceptors
  68. ASICs and mammalian mechanoreceptor function
  69. Photoswitchable fatty acids enable optical control of TRPV1
  70. GABA Blocks Pathological but Not Acute TRPV1 Pain Signals
  71. PIEZO2 is required for mechanotransduction in human stem cell–derived touch receptors
  72. Piezo2 is the major transducer of mechanical forces for touch sensation in mice
  73. A somatosensory circuit for cooling perception in mice
  74. Sensory mechanotransduction at membrane-matrix interfaces
  75. Inhibition of c-Kit signaling is associated with reduced heat and cold pain sensitivity in humans
  76. Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch
  77. Pro‐neurotrophins, sortilin, and nociception
  78. Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination
  79. Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objects
  80. Subunit‐specific inhibition of acid sensing ion channels by stomatin‐like protein 1
  81. Nerve Growth Factor and Nociception: From Experimental Embryology to New Analgesic Therapy
  82. Natural Selection and Pain Meet at a Sodium Channel
  83. Stomatin-domain protein interactions with acid-sensing ion channels modulate nociceptor mechanosensitivity
  84. Hairy Sensation
  85. A stomatin dimer modulates the activity of acid-sensing ion channels
  86. Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1
  87. Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons
  88. Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: Comparative analysis using six species of bathyergidae
  89. A Genetic Basis for Mechanosensory Traits in Humans
  90. Stomatin-domain proteins
  91. Presynaptically Localized Cyclic GMP-Dependent Protein Kinase 1 Is a Key Determinant of Spinal Synaptic Potentiation and Pain Hypersensitivity
  92. The Transcription Factor c-Maf Controls Touch Receptor Development and Function
  93. Gαq/11 signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization
  94. The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat
  95. KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
  96. Erratum: Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
  97. Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons
  98. The Cav3.2 T-type calcium channel regulates temporal coding in mouse mechanoreceptors
  99. Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice
  100. The Molecular and Cellular Identity of Peripheral Osmoreceptors
  101. Functional Neurokinin and NMDA Receptor Activity in an Animal Naturally Lacking Substance P: The Naked Mole-Rat
  102. Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
  103. Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation
  104. RAPID REPORT: Anin vivotethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors
  105. Evidence for a protein tether involved in somatic touch
  106. Absence of Histamine-Induced Itch in the African Naked Mole-Rat and “Rescue” by Substance P
  107. Nociceptors: a phylogenetic view
  108. Peripheral sensitisation of nociceptors via G-proteindependent potentiation of mechanotransduction currents
  109. Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development
  110. Speed and Temperature Dependences of Mechanotransduction in Afferent Fibers Recorded From the Mouse Saphenous Nerve
  111. Stretching it for pain
  112. Selective Inflammatory Pain Insensitivity in the African Naked Mole-Rat (Heterocephalus glaber)
  113. Nociceptive Tuning by Stem Cell Factor/c-Kit Signaling
  114. Stomatin and Sensory Neuron Mechanotransduction
  115. Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury
  116. A stomatin-domain protein essential for touch sensation in the mouse
  117. Mechanosensitive currents in the neurites of cultured mouse sensory neurones
  118. A role for T-type Ca2+ channels in mechanosensation
  119. The high threshold mechanotransducer: A status report
  120. Chapter 13 Finding Sensory Neuron Mechanotransduction Components
  121. A plethora of painful molecules [Curr. Opin. Neuro. 14 (2004) 443]
  122. The sensory mechanotransduction ion channel ASIC2 (acid sensitive ion channel 2) is regulated by neurotrophin availability
  123. The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function
  124. The AMPA Receptor Subunits GluR-A and GluR-B Reciprocally Modulate Spinal Synaptic Plasticity and Inflammatory Pain
  125. Role of T-Type Calcium Current in Identified D-Hair Mechanoreceptor Neurons Studied In Vitro
  126. A plethora of painful molecules
  127. Mechanosensation and pain
  128. A T-type calcium channel required for normal function of a mammalian mechanoreceptor
  129. Identification of Caveolae-like Structures on the Surface of Intact Cells Using Scanning Force Microscopy
  130. cGMP-mediated signaling via cGKIα is required for the guidance and connectivity of sensory axons
  131. GFRα2/neurturin signalling regulates noxious heat transduction in isolectin B4-binding mouse sensory neurons
  132. Neurotrophin-4
  133. The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice
  134. Erratum: corrigendum: The mammalian sodium channel BNC1 is required for normal touch sensation
  135. The Homeodomain Factor Lbx1 Distinguishes Two Major Programs of Neuronal Differentiation in the Dorsal Spinal Cord
  136. Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons
  137. The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice
  138. BDNF but not NT-4 is required for normal flexion reflex plasticity and function
  139. Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin
  140. Lack of Neurotrophin-4 Causes Selective Structural and Chemical Deficits in Sympathetic Ganglia and Their Preganglionic Innervation
  141. Neurotrophins, nociceptors and pain
  142. The mammalian sodium channel BNC1 is required for normal touch sensation
  143. Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors
  144. Cellular Sources of Enhanced Brain-Derived Neurotrophic Factor Production in a Mouse Model of Allergic Inflammation Notice to Professional Recruitment and Announcement Advertisers
  145. Abundant Production of Brain-Derived Neurotrophic Factor by Adult Visceral Epithelia
  146. Isolectin B4-Positive and -Negative Nociceptors Are Functionally Distinct
  147. Stomatin, a MEC-2 Like Protein, Is Expressed by Mammalian Sensory Neurons
  148. Stability and plasticity of primary afferent projections following nerve regeneration and central degeneration
  149. A new role for neurotrophins: involvement of brain‐derived neurotrophic factor and neurotrophin‐4 in hair cycle control
  150. Neurotrophins: A Link between Airway Inflammation and Airway Smooth Muscle Contractility in Asthma?
  151. BDNF overexpression induces differential increases among subsets of sympathetic innervation in murine back skin
  152. A New Role for Neurotrophin-3
  153. Point Mutation in trkB Causes Loss of NT4-Dependent Neurons without Major Effects on Diverse BDNF Responses
  154. Neurotrophin-3 Involvement in the Regulation of Hair Follicle Morphogenesis
  155. A role for BDNF in mechanosensation
  156. Receptive Properties of Embryonic Chick Sensory Neurons Innervating Skin
  157. Severe neuropathies in mice with targeted mutations in the ErbB3 receptor
  158. Receptive Properties of Mouse Sensory Neurons Innervating Hairy Skin
  159. Neurotrophins Live or Let Die: Does p75NTR Decide?
  160. Maintenance of Modality-specific Connections in the Spinal Cord after Neonatal Nerve Growth Factor Deprivation
  161. Neurotrophins and the specification of neuronal phenotype
  162. Roles of neurotrophin-3 during early development of the peripheral nervous system
  163. Physiology of the Neurotrophins
  164. Specific Subtypes of Cutaneous Mechanoreceptors Require Neurotrophin-3 Following Peripheral Target Innervation
  165. Neurotrophic factors and pain
  166. Peripheral and Central Mechanisms of NGF-induced Hyperalgesia
  167. NMDA receptors and activity-dependent tuning of the receptive fields of spinal cord neurons
  168. Regulation of cutaneous C-fiber heat nociceptors by nerve growth factor in the developing rat
  169. An ultrastructural size principle
  170. Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli
  171. Nerve growth factor and nociception
  172. Central hyperexcitability triggered by noxious inputs
  173. Muscle Afferents Innervating Skin Form Somatotopically Appropriate Connections in the Adult Rat Dorsal Horn
  174. Regulation of myelinated nociceptor function by nerve growth factor in neonatal and adult rats
  175. Neonatal Anti-NGF Treatment Reduces the Aδ- and C-Fibre Evoked Vasodilator Responses in Rat Skin: Evidence That Nociceptor Afferents Mediate Antidromic Vasodilatation
  176. Regulation of Afferent Connectivity in the Adult Spinal Cord by Nerve Growth Factor
  177. Removing constraints on neural sprouting
  178. Dorsal Horn Plasticity Following Re-routeing of Peripheral Nerves: Evidence for Tissue-Specific Neurotrophic Influences from the Periphery
  179. Physiological properties of primary sensory neurons appropriately and inappropriately innervating skeletal muscle in adult rats
  180. Physiological properties of primary sensory neurons appropriately and inappropriately innervating skin in the adult rat
  181. Requirement for nerve growth factor in the development of myelinated nociceptors in vivo
  182. The consequences of long-term topical capsaicin application in the rat
  183. Increase of blood flow in skin and spinal cord following activation of small diameter primary afferents
  184. Quantitative analysis of peptide levels and neurogenic extravasation following regeneration of afferents to appropriate and inappropriate targets