All Stories

  1. The evolution of IgE‐mediated type I hypersensitivity and its immunological value

    Article • Allergy, September 2020, Wiley

    Franco Falcone

  2. Use of BODIPY-Labeled ATP Analogues in the Development and Validation of a Fluorescence Polarization-Based Assay for Screening of Kinase Inhibitors

    Article • ACS Omega, April 2020, American Chemical Society (ACS)

    Franco Falcone

  3. Introduction of a C-terminal hexa-lysine tag increases thermal stability of the LacDiNac binding adhesin (LabA) exodomain from Helicobacter pylori

    Article • Protein Expression and Purification, November 2019, Elsevier

    Franco Falcone

  4. Characterization of human FcεRIα chain expression and gene copy number in humanized rat basophilic leukaemia (RBL) reporter cell lines

    Article • PLoS ONE, August 2019, PLOS

    Franco Falcone

  5. IPSE, a parasite-derived host immunomodulatory protein, is a potential therapeutic for hemorrhagic cystitis

    Article • AJP Renal Physiology, June 2019, American Physiological Society

    Franco Falcone, Abdulaziz Alouffi

  6. IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways

    Article • Scientific Reports, February 2019, Springer Science + Business Media

    Franco Falcone, Abdulaziz Alouffi

  7. Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis

    Article • The FASEB Journal, August 2018, Federation of American Societies For Experimental Biology (FASEB)

    Michael Hsieh, Franco Falcone, Abdulaziz Alouffi

  8. Polyionic Tags as Enhancers of Protein Solubility in Recombinant Protein Expression

    Article • Microorganisms, May 2018, MDPI AG

    Franco Falcone

  9. Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery

    Article • International Journal of Pharmaceutics, April 2018, Elsevier

    Franco Falcone

  10. RBL cells as models for in vitro studies of mast cells and basophils

    Article • Immunological Reviews, February 2018, Wiley

    Franco Falcone

  11. Screening natural libraries of human milk oligosaccharides against lectins using CaR-ESI-MS

    Article • The Analyst, January 2018, Royal Society of Chemistry

    Franco Falcone

  12. H-IPSE Is a Pathogen-Secreted Host Nucleus-Infiltrating Protein (Infiltrin) Expressed Exclusively by the Schistosoma haematobium Egg Stage

    Article • Infection and Immunity, September 2017, ASM Journals

    Franco Falcone, Abdulaziz Alouffi

  13. Use of Humanized RS-ATL8 Reporter System for Detection of Allergen-Specific IgE Sensitization in Human Food Allergy

    Article • January 2017, Springer Science + Business Media

    Franco Falcone

  14. Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

    Article • World Allergy Organization Journal, January 2016, Elsevier

    Franco Falcone

  15. Use of Humanized Rat Basophilic Leukemia Reporter Cell Lines as a Diagnostic Tool for Detection of Allergen-Specific IgE in Allergic Patients: Time for a Reappraisal?

    Article • Current Allergy and Asthma Reports, October 2015, Springer Science + Business Media

    Franco Falcone

  16. Live Imaging of Cellular Internalization of Single Colloidal Particle by Combined Label-Free and Fluorescence Total Internal Reflection Microscopy

    Article • Molecular Pharmaceutics, October 2015, American Chemical Society (ACS)

    Franco Falcone

  17. Structural basis of Lewisb antigen binding by the Helicobacter pylori adhesin BabA

    Article • Science Advances, August 2015, American Association for the Advancement of Science

    Franco Falcone

  18. Correction: PRAME Is a Golgi-Targeted Protein That Associates with the Elongin BC Complex and Is Upregulated by Interferon-Gamma and Bacterial PAMPs

    Article • PLoS ONE, June 2015, PLOS

    Franco Falcone

  19. Improved expression and purification of the Helicobacter pylori adhesin BabA through the incorporation of a hexa-lysine tag

    Article • Protein Expression and Purification, February 2015, Elsevier

    Franco Falcone

  20. The search for mast cell and basophil models - are we getting closer to pathophysiological relevance?

    Article • Allergy, December 2014, Wiley

    Dr Ekaterini Tiligada, Franco Falcone

  21. High prevalence of chitotriosidase deficiency in Peruvian Amerindians exposed to chitin-bearing food and enteroparasites

    Article • Carbohydrate Polymers, November 2014, Elsevier

    Franco Falcone

  22. Use of Humanised Rat Basophilic Leukaemia Cell Line RS-ATL8 for the Assessment of Allergenicity of Schistosoma mansoni Proteins

    Article • PLoS Neglected Tropical Diseases, September 2014, PLOS

    Franco Falcone

  23. Mechanism of phosphatidylserine inhibition of IgE/FcεRI-dependent anaphylactic human basophil degranulation via CD300a

    Article • Journal of Allergy and Clinical Immunology, September 2014, Elsevier

    Franco Falcone

  24. Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules

    Article • Experimental Cell Research, April 2014, Elsevier

    Franco Falcone

  25. Serological Screening of the Schistosoma mansoni Adult Worm Proteome

    Article • PLoS Neglected Tropical Diseases, March 2014, PLOS

    Franco Falcone

  26. Helminth Allergens, Parasite-Specific IgE, and Its Protective Role in Human Immunity

    Article • Frontiers in Immunology, January 2014, Frontiers

    Franco Falcone

  27. Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Franco Falcone

  28. Basophils and Mast Cells

    Article • January 2014, Springer Science + Business Media

    Franco Falcone

  29. Purification of Basophils from Peripheral Human Blood

    Article • January 2014, Springer Science + Business Media

    Franco Falcone

  30. Use of Humanized Rat Basophil Leukemia (RBL) Reporter Systems for Detection of Allergen-Specific IgE Sensitization in Human Serum

    Article • January 2014, Springer Science + Business Media

    Franco Falcone

  31. Uptake and transport of B 12 -conjugated nanoparticles in airway epithelium

    Article • Journal of Controlled Release, November 2013, Elsevier

    Franco Falcone

  32. Evidence Supporting a Role for Mammalian Chitinases in Efficacy of Caspofungin against Experimental Aspergillosis in Immunocompromised Rats

    Article • PLoS ONE, October 2013, PLOS

    Franco Falcone

  33. The history of mast cell and basophil research - some lessons learnt from the last century

    Article • Allergy, August 2013, Wiley

    Franco Falcone

  34. Optimisation and Use of Humanised RBL NF-AT-GFP and NF-AT-DsRed Reporter Cell Lines Suitable for High-Throughput Scale Detection of Allergic Sensitisation in Array Format and Identification of the ECM–Integrin Interaction as Critical Factor

    Article • Molecular Biotechnology, July 2013, Springer Science + Business Media

    Franco Falcone

  35. Basophilic histamine content and release during venom immunotherapy: Insights by flow cytometry

    Article • Cytometry Part B Clinical Cytometry, February 2013, Wiley

    Franco Falcone

  36. PRAME Is a Golgi-Targeted Protein That Associates with the Elongin BC Complex and Is Upregulated by Interferon-Gamma and Bacterial PAMPs

    Article • PLoS ONE, February 2013, PLOS

    Franco Falcone

  37. Anti-Fas/CD95 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) differentially regulate apoptosis in normal and neoplastic human basophils

    Article • Leukemia & Lymphoma, October 2012, Taylor & Francis

    Franco Falcone

  38. Prediction of tolerance in children with IgE mediated cow's milk allergy by microarray profiling and chemometric approach

    Article • Journal of Immunological Methods, August 2012, Elsevier

    Franco Falcone

  39. Ligand density and clustering effects on endocytosis of folate modified nanoparticles

    Article • RSC Advances, January 2012, Royal Society of Chemistry

    Franco Falcone

  40. Individual IL-3 priming is crucial for consistent in vitro activation of donor basophils in patients with chronic urticaria

    Article • Journal of Allergy and Clinical Immunology, December 2011, Elsevier

    Franco Falcone

  41. The role of basophils in the pathogenesis of allergic disease

    Article • Clinical & Experimental Allergy, May 2011, Wiley

    Franco Falcone

  42. Multiple protein extract microarray for profiling human food-specific immunoglobulins A, M, G and E

    Article • Journal of Immunological Methods, February 2011, Elsevier

    Franco Falcone

  43. Interleukin-4-Inducing Principle fromSchistosoma mansoniEggs Contains a Functional C-Terminal Nuclear Localization Signal Necessary for Nuclear Translocation in Mammalian Cells but Not for Its Uptake

    Article • Infection and Immunity, January 2011, ASM Journals

    Franco Falcone

  44. Experimental hookworm infection: a randomized placebo-controlled trial in asthma

    Article • Clinical & Experimental Allergy, February 2010, Wiley

    Franco Falcone

  45. Antigen-driven basophil activation is indicative of early Necator americanus infection in IgE-seronegative patients

    Article • Journal of Allergy and Clinical Immunology, December 2009, Elsevier

    Franco Falcone

  46. Alginate encapsulation technology supports embryonic stem cells differentiation into insulin-producing cells

    Article • Journal of Biotechnology, December 2009, Elsevier

    Franco Falcone

  47. Basophils as critical orchestrators of Th2-type immune responses

    Article • Expert Review of Clinical Immunology, November 2009, Taylor & Francis

    Franco Falcone

  48. Safety of hookworm infection in individuals with measurable airway responsiveness: a randomized placebo-controlled feasibility study

    Article • Clinical & Experimental Allergy, July 2009, Wiley

    Franco Falcone

  49. Total internal reflection microscopy for live imaging of cellular uptake of sub-micron non-fluorescent particles

    Article • Journal of Microscopy, July 2008, Wiley

    Franco Falcone

  50. A comparison of procedures for purifying human basophils to near homogeneity

    Article • Inflammation Research, March 2008, Springer Science + Business Media

    Franco Falcone

  51. A rapid two-step procedure for the purification of human peripheral blood basophils to near homogeneity

    Article • Clinical & Experimental Allergy, March 2008, Wiley

    Franco Falcone

  52. Human chitotriosidase is expressed in the eye and lacrimal gland and has an antimicrobial spectrum different from lysozyme

    Article • Microbes and Infection, January 2008, Elsevier

    Franco Falcone

  53. A novel tool for the detection of allergic sensitization combining protein microarrays with human basophils

    Article • Clinical & Experimental Allergy, December 2007, Wiley

    Franco Falcone

  54. Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population

    Article • Infection Genetics and Evolution, December 2007, Elsevier

    Franco Falcone

  55. The 21st century renaissance of the basophil? Current insights into its role in allergic responses and innate immunity

    Article • Experimental Dermatology, November 2006, Wiley

    Franco Falcone

  56. Lack of protease activated receptor (PAR) expression in purified human basophils

    Article • Inflammation Research, April 2005, Springer Science + Business Media

    Franco Falcone

  57. Parasite role reversal: worms on trial

    Article • Trends in Parasitology, April 2005, Elsevier

    Franco Falcone

  58. Le polynucléaire basophile et immunité anti-parasitaire : une mise à jour

    Article • Revue Française d Allergologie et d Immunologie Clinique, January 2004, Elsevier

    Franco Falcone

  59. The Innate Allergenicity of Helminth Parasites

    Article • Clinical Reviews in Allergy & Immunology, January 2004, Springer Science + Business Media

    Franco Falcone

  60. Molecular Characterization of an Interleukin-4-inducing Factor fromSchistosoma mansoniEggs

    Article • Journal of Biological Chemistry, March 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Franco Falcone

  61. A Brugia malayi Homolog of Macrophage Migration Inhibitory Factor Reveals an Important Link Between Macrophages and Eosinophil Recruitment During Nematode Infection

    Article • The Journal of Immunology, November 2001, The American Association of Immunologists

    Franco Falcone

  62. A glycoprotein from Schistosoma mansoni eggs binds non-antigen-specific immunoglobulin E and releases interleukin-4 from human basophils

    Article • Parasite Immunology, August 2001, Wiley

    Franco Falcone

  63. Ascaris suum-Derived Products Induce Human Neutrophil Activation via a G Protein-Coupled Receptor That Interacts with the Interleukin-8 Receptor Pathway

    Article • Infection and Immunity, June 2001, ASM Journals

    Franco Falcone

  64. Do basophils play a role in immunity against parasites?

    Article • Trends in Parasitology, March 2001, Elsevier

    Franco Falcone

  65. The New Subfamily of Cathepsin-Z-like Protease Genes Includes Tc-cpz-1, a Cysteine Protease Gene Expressed in Toxocara canis Adults and Infective Stage Larvae

    Article • Experimental Parasitology, March 2000, Elsevier

    Franco Falcone

  66. A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA

    Article • RNA, February 2000, Cold Spring Harbor Laboratory Press

    Franco Falcone

  67. Vaccination against helminth parasites - the ultimate challenge for vaccinologists?

    Article • Immunological Reviews, October 1999, Wiley

    Dr Martin Holland, Franco Falcone

  68. Early Interleukin–4: Its Role in the Switch towards a Th2 Response and IgE–Mediated Allergy

    Article • International Archives of Allergy and Immunology, January 1999, Karger Publishers

    Dr Martin Holland, Franco Falcone

  69. A three-step procedure for the purification of human basophils from buffy coat blood

    Article • Inflammation Research, April 1997, Springer Science + Business Media

    Franco Falcone

  70. Purified human peripheral blood basophils release interleukin-13 and preformed interleukin-4 following immunological activation

    Article • European Journal of Immunology, October 1996, Wiley

    Franco Falcone

  71. Human basophils release interleukin-4 after stimulation withSchistosoma mansoni egg antigen

    Article • European Journal of Immunology, May 1996, Wiley

    Franco Falcone