All Stories

  1. New Lipidyl-Cyclodextrins Obtained by Ring Opening of Methyl Oleate Epoxide Using Ball Milling

    Article • Biomolecules, February 2020, MDPI AG

    Pr. Fabien Gosselet, Professor Eric Monflier

  2. Ketone Bodies Promote Amyloid-β1–40 Clearance in a Human in Vitro Blood–Brain Barrier Model

    Article • International Journal of Molecular Sciences, January 2020, MDPI AG

    Pr. Fabien Gosselet

  3. A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters

    Article • International Journal of Molecular Sciences, November 2019, MDPI AG

    Pr. Fabien Gosselet

  4. Transient blood–brain barrier disruption is induced by low pulsed electrical fields in vitro: an analysis of permeability and trans-endothelial electric resistivity

    Article • Drug Delivery, January 2019, Taylor & Francis

    Pr. Fabien Gosselet

  5. A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow

    Article • Journal of Cerebral Blood Flow & Metabolism, December 2018, SAGE Publications

    Pr. Fabien Gosselet

  6. Corrigendum to “Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration” [Eur. J. Pharm. Biopharm. 127 (2018) 453–461]

    Article • European Journal of Pharmaceutics and Biopharmaceutics, December 2018, Elsevier

    Pr. Fabien Gosselet

  7. Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties

    Article • Frontiers in Cellular Neuroscience, October 2018, Frontiers

    Pr. Fabien Gosselet

  8. HIV Neuroinfection and Alzheimer’s Disease: Similarities and Potential Links?

    Article • Frontiers in Cellular Neuroscience, September 2018, Frontiers

    Pr. Fabien Gosselet

  9. ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier

    Article • Journal of Alzheimer s Disease, July 2018, IOS Press

    Pr. Fabien Gosselet

  10. Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment

    Article • International Journal of Pharmaceutics, July 2018, Elsevier

    Pr. Fabien Gosselet

  11. Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells

    Article • Molecular Pharmaceutics, June 2018, American Chemical Society (ACS)

    Pr. Fabien Gosselet

  12. Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2018, Elsevier

    Pr. Fabien Gosselet

  13. Food-Derived Hemorphins Cross Intestinal and Blood–Brain Barriers In Vitro

    Article • Frontiers in Endocrinology, April 2018, Frontiers

    Pr. Fabien Gosselet

  14. Petits mais costauds

    Article • médecine/sciences, April 2018, EDP Sciences

    Pr. Fabien Gosselet

  15. Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers

    Article • Fluids and Barriers of the CNS, October 2017, Springer Science + Business Media

    Pr. Fabien Gosselet

  16. Brain tissue binding explains discrepancy between in vitro and in vivo methods for assessing blood–brain barrier permeability of chemicals

    Article • Toxicology Letters, October 2017, Elsevier

    Pr. Fabien Gosselet

  17. Disease-Induced Alterations in Brain Drug Transporters in Animal Models of Alzheimer’s Disease

    Article • Pharmaceutical Research, September 2017, Springer Science + Business Media

    Pr. Fabien Gosselet

  18. Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

    Article • Journal of Medicinal Chemistry, May 2017, American Chemical Society (ACS)

    Pr. Fabien Gosselet

  19. Modélisation in vitro de la barrière hémato-encéphalique

    Article • médecine/sciences, April 2017, EDP Sciences

    Pr. Fabien Gosselet

  20. Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease

    Article • Molecules, February 2017, MDPI AG

    Pr. Fabien Gosselet

  21. Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases

    Article • Molecules, December 2016, MDPI AG

    Pr. Fabien Gosselet, Professor Eric Monflier

  22. ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier

    Article • Journal of Cerebral Blood Flow & Metabolism, November 2016, SAGE Publications

    Pr. Fabien Gosselet

  23. ST6GALNAC5 Expression Decreases the Interactions between Breast Cancer Cells and the Human Blood-Brain Barrier

    Article • International Journal of Molecular Sciences, August 2016, MDPI AG

    Pr. Fabien Gosselet

  24. Modulation of Amyloid-β1–40 Transport by ApoA1 and ApoJ Across an in vitro Model of the Blood-Brain Barrier

    Article • Journal of Alzheimer s Disease, July 2016, IOS Press

    Pr. Fabien Gosselet

  25. In vitro blood–brain barrier permeability predictions for GABA A receptor modulating piperine analogs

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2016, Elsevier

    Pr. Fabien Gosselet

  26. β-Cyclodextrins Decrease Cholesterol Release and ABC-Associated Transporter Expression in Smooth Muscle Cells and Aortic Endothelial Cells

    Article • Frontiers in Physiology, May 2016, Frontiers

    Pr. Fabien Gosselet, Professor Eric Monflier

  27. Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin

    Article • Planta Medica, April 2016, Thieme Publishing Group

    Professor Matthias Hamburger, Dr Maria A Deli, Pr. Fabien Gosselet

  28. Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines

    Article • PLoS ONE, March 2016, PLOS

    Pr. Fabien Gosselet

  29. Adapting coculture in vitro models of the blood–brain barrier for use in cancer research: maintaining an appropriate endothelial monolayer for the assessment of transendothelial migration

    Article • Laboratory Investigation, February 2016, Springer Science + Business Media

    Pr. Fabien Gosselet

  30. Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models

    Article • Toxicology in Vitro, December 2015, Elsevier

    Professor Dieter G. Weiss, Pr. Fabien Gosselet

  31. Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier

    Article • Journal of Alzheimer s Disease, October 2015, IOS Press

    Pr. Fabien Gosselet

  32. Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid

    Article • Molecular Neurobiology, June 2015, Springer Science + Business Media

    Pr. Fabien Gosselet

  33. In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes

    Article • Brain Research, January 2015, Elsevier

    Pr. Fabien Gosselet

  34. Blood–Brain Barrier Proteomics: Towards the Understanding of Neurodegenerative Diseases

    Article • Archives of Medical Research, November 2014, Elsevier

    Pr. Fabien Gosselet

  35. Effects of oxysterols on the blood–brain barrier: Implications for Alzheimer’s disease

    Article • Biochemical and Biophysical Research Communications, April 2014, Elsevier

    Pr. Fabien Gosselet

  36. Amyloid-β Peptides, Alzheimer's Disease and the Blood-brain Barrier

    Article • Current Alzheimer Research, December 2013, Bentham Science Publishers

    Pr. Fabien Gosselet

  37. Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells

    Article • Brain Research, June 2013, Elsevier

    Pr. Fabien Gosselet

  38. Truncated thioredoxin (Trx‐80) promotes pro‐inflammatory macrophages of the M1 phenotype and enhances atherosclerosis

    Article • Journal of Cellular Physiology, March 2013, Wiley

    Pr. Fabien Gosselet

  39. Apolipoprotéine E et intégrité de la barrière hémato-encéphalique

    Article • médecine/sciences, November 2012, EDP Sciences

    Pr. Fabien Gosselet

  40. Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-β Peptide Accumulation

    Article • Journal of Alzheimer s Disease, June 2012, IOS Press

    Pr. Fabien Gosselet

  41. Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro

    Article • Fluids and Barriers of the CNS, January 2012, Springer Science + Business Media

    Pr. Fabien Gosselet

  42. A differential proteomic approach identifies structural and functional components that contribute to the differentiation of brain capillary endothelial cells

    Article • Journal of Proteomics, December 2011, Elsevier

    Dr LUC CAMOIN, Pr. Fabien Gosselet

  43. Modelling the Neurovascular Unit and the Blood-Brain Barrier with the Unique Function of Pericytes

    Article • Current Neurovascular Research, November 2011, Bentham Science Publishers

    Pr. Fabien Gosselet

  44. La barrière hémato-encéphalique

    Article • médecine/sciences, November 2011, EDP Sciences

    Pr. Fabien Gosselet

  45. The Mysterious Link between Cholesterol and Alzheimer?s Disease: Is the Blood-Brain Barrier a Suspect?

    Article • Journal of Alzheimer’s Disease & Parkinsonism, January 2011, OMICS Publishing Group

    Pr. Fabien Gosselet

  46. Apical-to-Basolateral Transport of Amyloid-β Peptides through Blood-Brain Barrier Cells is Mediated by the Receptor for Advanced Glycation End-Products and is Restricted by P-Glycoprotein

    Article • Journal of Alzheimer s Disease, November 2010, IOS Press

    Pr. Fabien Gosselet

  47. Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood–brain barrier: Use of an in vitro model

    Article • Brain Research, January 2009, Elsevier

    Pr. Fabien Gosselet

  48. Physiological Pathway for Low-Density Lipoproteins across the Blood-Brain Barrier: Transcytosis through Brain Capillary Endothelial Cells In Vitro

    Article • Endothelium, January 2008, Taylor & Francis

    Pr. Fabien Gosselet

  49. BMP2 and BMP6 control p57Kip2 expression and cell growth arrest/terminal differentiation in normal primary human epidermal keratinocytes

    Article • Cellular Signalling, April 2007, Elsevier

    Pr. Fabien Gosselet

  50. UVB-induced mutations in human key gatekeeper genes governing signalling pathways and consequences for skin tumourigenesis

    Article • Photochemical & Photobiological Sciences, August 2003, Springer Science + Business Media

    Pr. Fabien Gosselet