All Stories

  1. Synthetic Lethality between PTEN loss and Pyruvate Dehydrogenase Kinase 1

    Article • Cell Reports, August 2019, Elsevier

    Dr Evangelos Pazarentzos

  2. Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  3. The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood–brain barrier in vitro

    Article • Brain Research, October 2016, Elsevier

    Dr Evangelos Pazarentzos

  4. RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK–positive lung cancer

    Article • Nature Medicine, August 2015, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  5. Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3CβD1067V kinase domain mutation

    Article • Oncogene, May 2015, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  6. NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer

    Article • Cell Reports, April 2015, Elsevier

    Dr Evangelos Pazarentzos

  7. AXL Mediates Resistance to PI3Kα Inhibition by Activating the EGFR/PKC/mTOR Axis in Head and Neck and Esophageal Squamous Cell Carcinomas

    Article • Cancer Cell, April 2015, Elsevier

    Dr Evangelos Pazarentzos

  8. Adaptive stress signaling in targeted cancer therapy resistance

    Article • Oncogene, February 2015, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  9. The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

    Article • Nature Genetics, February 2015, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  10. Stefan Grimm, 1963–2014, a tragic loss for the scientific community

    Article • Cell Death and Differentiation, January 2015, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  11. IkBa inhibits apoptosis via interacting with VDAC and Hexokinase 2

    Article • The EMBO Journal, October 2014, EMBO

    Dr Evangelos Pazarentzos

  12. Mitochondrial Ca2+ influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction

    Article • Cell Death and Differentiation, June 2014, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  13. The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis

    Article • Oncogene, April 2014, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  14. CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex

    Article • Journal of Cell Science, February 2014, The Company of Biologists

    Dr Evangelos Pazarentzos

  15. Anticancer Gene Transfer for Cancer Gene Therapy

    Article • January 2014, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  16. Dose-dependent Neuroprotection of VEGF165 in Huntington's Disease Striatum

    Article • Molecular Therapy, October 2013, Elsevier

    Dr Evangelos Pazarentzos

  17. De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, August 2012, Elsevier

    Dr Evangelos Pazarentzos

  18. De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF

    Article • Cell Death and Differentiation, December 2011, Springer Science + Business Media

    Dr Evangelos Pazarentzos

  19. Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction

    Article • The EMBO Journal, December 2010, Wiley

    Dr Evangelos Pazarentzos

  20. Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction

    Article • Cell Death and Differentiation, August 2010, Springer Science + Business Media

    Dr Evangelos Pazarentzos